Alternativ splicing av pre-mRNA ger upphov till proteindiversitet. Histonmodifieringar kopplas till den alternativa splicingens reglering genom adaptorsystem som overfor den epigenetiska informationen direkt till splicingfaktorerna. De cis- agerande RNA- elementen pa exoner och introner med tillhorande trans- reglerande splicingfaktorer paverkas darfor direkt av specifika histonmodifieringar. En sammankopplande integrerad modell over en rad DNA- baserade processer foreslas. Denna komplexa modell ger en bild av interaktioner och paverkan mellan dessa delar.

This essay set out to propose a problematic interpretation of the socio-cultural perspective on learning. Its purpose is to show how the socio-cultural perspective on learning defines the concept of knowledge in an incomplete way. The aim becomes then that of giving a more comprehensive description of this concept, and, to this end, to construct a new, broader pedagogic discourse. The investigation starts with a deconstructive analysis of Roger Säljö?s socio-cultural text in order to point out the incompleteness of the concept of knowledge.

Coordinator of public health has recently become a new profession in the field of Health Promotion. During the last few years the pedagogic perspective has been increasingly important for the coordinators as a way of adapting their work methods to the circumstances. The conditions for coordinators of public health differ between municipalities and thus their tasks and responsibilities may vary with the local structure. According to the literature there are several ways to conduct Health Promotion and it is in the hands of the coordinator to adjust the methods to fit local conditions. The purpose of the study was to examine what influences the coordinators of public health and how that affects their work methods.

Family centres are established to serve families with children and the personnel usually consists of units of social-workers, preschool staff, paediatric nurses and midwives. The purpose of the study was to examine the social-workers preventive work with families at the family centre. To fulfil the purpose, a qualitative interview with five social-workers was conducted. The theoretical framework referred to attachment and empowerment theory. The results of the study showed that the main part of the work consists of giving advice and support to parents.

Inom skogsnäringen sker idag en omfattande strukturomvandling. Från att ha varit en fragmenterad bransch med många små aktörer går nu företagen samman i internationella koncerner. Bland kooperativa företag sker även en utveckling mot alternativa former av kooperativa företag. Dessa bildas för att bättre möta omvärldens krav. Bland annat ägar-strukturen är under förändring genom att externa ägare bjuds in i olika utsträckning.

Varje år begår ungefär 1100 personer självmord i Sverige, fortfarande finns det många obesvarade frågor om hur självmord kan förhindras. Syftet med denna studie är att undersöka om graden av social integration i ett samhälle kan förklara de skillnader i självmordstal som råder mellan Sveriges kommuner. Èmile Durkheims teori om egoistiska självmord har använts som teoretisk utgångspunkt och i tolkningen av studiens resultat. Studien bygger på data från statistikansvariga myndigheter samt data över självuppskattad hälsa från den nationella folkhälsoenkäten. För att analysera datan har vi använt oss av korrelationsanalyser och regressionsanalyser som vi gjort i statistikprogrammet SPSS.

Lymphoma is a group of malignant tumour diseases developing in the secondary lymphatic system. These diseases can develop in all organs as lymphocytes are ubiquitously in the body. In connection to mucus membranes we find mucosa-associated lymphoid tissue, MALT, in which lymphoma can spontaneously but slowly develop, mostly at chronic inflammation or at autoimmune diseases. Today these diseases are incureable with the exception of some cases caused by Helicobacter pylori-infection. Antibiotic treatment of these cases can induce remissions.MALT-lymphomas have characteristic histological and molecular properties.

Rapporten ingår i ett FoU- projekt för Högskolan Dalarna, där målet är att ta fram en konstruktion utan ångspärr som ska klara dagens mått på lufttäthet och fuktkrav.Syftet med denna rapport är att utreda hur fukt påverkar en byggnad medmassivträstomme och olika isoleringsmaterial utan ångspärr. Mineralull och träfiberisolering jämförs mot varandra för att se hur dessa påverkarfuktbelastningen i en väggkonstruktion. Testobjektet är lokaliserat i Dalarna, inget fukttillskott har funnits inomhus i byggnaden.För att genomföra detta arbete har tre stycken olika metoder används. Ensimulering, verkliga uppmätta värden och en provtagning. Fuktsimuleringen genomfördes med hjälp av programmet WUFI, uppmätta värden i form av relativ fuktighet och temperatur har samlats in kontinuerligt under två års tid från väggkonstruktionen via mätsensorer.

Author: Gabriella Agné and Helena LarssonTitle: Disability policy program ? a case study of a municipals implementation of UNs Convention on the Rights of Persons with Disabilities.Supervisor: Marianne Westring-NordhAssessor: Ulf DruggeThis study aims to examine how a small municipal in southern Sweden works with the implementation of the UN Convention on the Rights of Persons with Disabilities and examine the assistant officers knowledge about this work and user organizations inclusion and user involvement.The study operates from a qualitative approach based on the results of nine semi-structured interviews with local politicians, assistance officers and representatives from three different user organizations.The results show that the municipal has chosen to work with the implementation of the convention by creating policy programs for their departments through dialogue with user organizations, and by mapping the accessibility to public places. The results also show that the assistant officers have been given no information regarding the convention or the policy programs from their employers and instead operate from national legislations and prepositions. The user organizations feel that they were initially included in the process, but that their impact has later been removed due to structural reorganization..

The structural rationalization of rural firms in Sweden has led to many new creative ways of developing companies. The agriculture sector is characterized by the need of capital in form of buildings, labor and inventory. The rationalization process has led to free capacity in rural firms when new technology make buildings and inventory not longer necessary for the production process. To get a better cost coverage this free capacity can be used to start-up new business areas that help the rural firm to growth.The study aims to identify factors that motives entrepreneurs in rural firms to develop new business areas. The purpose is also to analyze driving forces that lies behind development of rural firms and the forces that support or not support development in rural firms.The study is built upon five cases that all can be categorized as firms with different size and orientation.

The intention of this essay is to inquire into the (re-)constitution of gendered/sexed identities in a gothicistic discourse. The used material is the work Atlantica, chapter 5, vol. 2, written by the Swedish historian/Medical professor Olof Rudbeck. I have chosen this chapter for its description of mythological characters relationship with the earth, the sun and the moon. A description based on a concept of strength and reproduction as gendered characteristics.

Introduction: Public health is based on the determinants of health. They mutually influence each other. Structural factors and life conditions contribute to health inequality both within and between countries. Health inequality can be seen between different social groups, which can be the cause of differences in living conditions, health behavior and disease vulnerability. One of the consequences of this is segregation which means that certain groups live apart, where this distribution can be connected to economic resources and/or ethnicity.

This is an interview based qualitative case study on two Women's Migrant Associations in Malmoe, which I interpret as being part of a women's movement, with characteristics of a new social movement. The aim of this study is to get a deeper understanding on how the collective identity is being constructed, in this women's movement where the membership is not based on an exclusive ethnic identity.I make a two dimensional analysis that departs from a social constructivist underpinning, including the theories Transversial Politics, Postcolonial feminism and New Social Movement Theory.First I analyze the construction of collective identity from the external social and cultural context, and get confirmed that the collective identity of the movement is based on a common experience of social exclusion and a plurality of actions that aims to fight the structural injustices based on gender and ethnic discrimination. Secondly I analyze how the collective identity is being constructed and maintained from the interactions between the members of the movement, from an understanding of Transversial Politics. My findings show that the members of the movement interact in a participatory democratic way which generally corresponds to Transversial Politics. According to Transversial Politics this can lead to a construction of an empowered inclusive collective identity for the members and as my empirical study confirms it also means possibilities for deconstruction of boundaries between social groups..

Coordinator of public health has recently become a new profession in the field of Health Promotion. During the last few years the pedagogic perspective has been increasingly important for the coordinators as a way of adapting their work methods to the circumstances. The conditions for coordinators of public health differ between municipalities and thus their tasks and responsibilities may vary with the local structure. According to the literature there are several ways to conduct Health Promotion and it is in the hands of the coordinator to adjust the methods to fit local conditions. The purpose of the study was to examine what influences the coordinators of public health and how that affects their work methods.

Purpose: The purpose of this thesis is to test for the existence of Capital Structure Arbitrage oppertunities in the equity-credit markets. Methodology: The mispricing of Credit Default Swap contracts are calculated and used as input in an Equity-Credit market trading strategy. The returns are then evaluated with a modified Value-at-Risk simulation. Theoretical perspectives: A Merton-based structural model, CreditGrades, is used for credit pricing and a mispricing-convergence trading-strategy between the credit and equity markets is implemented. Empirical foundation: Daily quotes for the Credit Default Swap spread of 37 European firms were collected for a period of two years, as well as equity-prices for the same period and the previous two years, used for model calibration.