The search for antibiotic compounds from the natural environment has been going on for seven decades, ever since penicillin entered the market and antibiotic treatments became routine. The evolutionary pressure put on the pathogenic microorganisms induced a rapid spreading of naturally occurring resistance genes, leaving only the option of finding new antibiotics to treat the resistant pathogens. Microorganisms have been extensively mined for their biosynthetic abilities to produce biologically active compounds. To date, more than 23 000 microbial natural products have been discovered. The Actinomycetales are ubiquitous bacteria that have been used for antibiotic discovery for more than half a century, and over 10 000 natural products have been identified from the order.

Background: The speech- and language deficit aphasia affects 12 000 persons annually in Sweden. Aphasia is caused by injury in the brain and the most common etiology is stroke. According to the tool for describing and assessing aphasia, A-FROM (Kagan et al., 2008), the four following aspects of aphasia need to be considered: severity of aphasia, participation in life situations, communication and language environment and personal factors. Several different interventions and treatments can be performed in every domain. There is scientific evidence for interventions performed by speech and language pathologists; however, the question is yet being discussed since results are unambiguous.Purpose: The main purpose of this study is to investigate which aphasia interventions performed by speech and language pathologists that are supported by evidence.

The purpose of this study was to create a deeper understanding for, and shine a light on the exit process for former criminal gang members. Which conditions appear to be important and what may constitute the enabling and inhibiting factors of an exit process? The study was based on qualitative semi-structured interviews with respondents who themselves have experience of a criminal lifestyle and gang affiliation, and with professionals in social work. Our theoretical approach is based on Helen Ebaugh?s definition of an exit process, labeling theories, strain theory and control theory.

Sports research in the field of social science has shown that regular physical activity leads to wellbeing and positively affects the quality of life. A natural part of being an athlete is learning the functions of the human body, and what?s harmful and destructive, such as drugs (RF 1995). Doping is a constant problem in professional sport. Doping and manipulation of medical preparations in order to maximise performance is one of modern sport?s major problems, according to Blom and Lindroth (1995).I thought it would be interesting to see what the next generation of athletes thinks of doping.

This master thesis concerns the occupational safetyenvironment at Outokompu Stainless, Avesta Work.The study is of a sociotechnical approach wherehumans are involved and interconnected in the samesystem with technology and organisation. In order toreach the corporation?s goal of zero accidents with losttime injury, the work of improving and maintainoccupational safety and health has to regard behaviourand cultural aspects. The aim of this study is todescribe the safety culture at a specific production unitand research what work which has to be done in orderto change and improve the safety culture at AvestaWork.There are several opportunities for improvementpointed out in this paper and here are some mainresults presented. First and foremost, the concern ofsafety among blue-collar is often secondary due toproduction.

When designing roads it?s important to knowwhat loads will bedriven on it. The axles on heavy vehicles can either have super single tires ordual tires which, according to studies, damage the roads differently. The SwedishTransport Administration is developing an understanding for the character ofthese different kinds of axle and tire types on the loads induced on Swedishroads. In this thesis a field study was conducted to determine the distributionbetween axles with super single tires and axles with dual tires on heavy vehicles.A highway, a country road and a national road were investigated during thestudy.

Varje år drabbas ett tusental människor i Sverige av allvarlig brännskada, en skada som kommer att förändra deras liv för alltid. Sjuksköterskan kan dagligen möta människor som känner sig stigmatiserade, kanske utan att hon vet om det. Den brännskadade kan inte dölja sitt yttre och sjuksköterskan kan inte låta bli att lägga märke till det. Syftet med denna studie är att belysa hur människor som drabbats av allvarlig brännskada upplever sin livssituation efter skadan. Resultatet är sammanställt genom analys av sex kvalitativa artiklar.

Background: Critical conditions to become an attractive supplier of knowledge based IT-services in the B2B market are many. Besides the fact of supplying a service of high quality one must as a supplier communicate values which are understandable and desirable for a new buyer. Buying a knowledge based IT-service involves several risks; the consultant might not have sufficient knowledge or have difficulties understanding the corporate culture and collaborating with other staff within the client?s organization. Since services are intangible offers and it can be intricate to put right price level for something which can only be evaluated when the project is finished, puts severe strain on suppliers competing with other companies in the same market when looking for new clients.

The fact that animals have feelings is something that is commonly agreed. Many authors showhow animals' views of their environment is quite similar with human views. Animals, whichare slaughtered without prior stunning, find the moment of slaughter unpleasant and stressing.This is shown in numerous of scientific studies. The cognitive ability of animals can becompared to how they experience feelings and scientists have shown how the structures in thebrain that involves feelings and cognitive behaviours in animals are very much the same asthe structures in human brains. Because of this, some scientists consider that behaviour inanimals can be directly interpreted into human feelings.Halal- and kosher slaughter comes from traditions.

Today the individual ventilated cage system (IVC-system) is a commonly used housing system for mice in research facilities. IVC systems have HEPA- filters and are designed to control both supply and exhausted air at cage level, as well as temperature and relative humidity in the cages. This creates an optimal environment for the mouse and at the same time a protection against the risk of cross-infection between cages and the outside environment. The aim of this study was to evaluate the health and welfare of breeding females and pups of two different strains of laboratory mice (NMRI nude mice and C57BL/6N) in three different kinds of IVC-systems; Arrowmight, Allentown and Tecniplast. The NMRI nude (Nu) females gave birth to 18 litters in Allentown, 16 litters in Arrowmight and 15 litters in Tecniplast.

Studier har visat att utrustningsorsakade munhåleskador är vanligt hos svenska rid- och travhästar i träning. Förekomst av utrustningsrelaterade skador på regelbundet ridna Islandshästar finns dock inte beskriven i litteraturen. Inte heller har ett tävlingsmoments eventuella inverkan på munhälsan hos hästar undersökts. Tre olika grupper av Islandshästar i olika rid/träningsstatus har undersökts. Grupp 1 bestod av tävlande hästar som precis avslutat ett tävlingsdeltagande.

This study is about children that have been forced to flee to another country, due to conflict, poverty or natural disasters, without their families. They are known as unaccompanied refugee children. The aim of the study is to, by focusing on individual children's feelings and experiences of being forced to flee create greater knowledge and understanding of what is hidden behind some of the statistic of migration.To answer the aim of the study, I used the following research questions: How is a child affected by being forced to leave home and to flee to a foreign country? How does an unaccompanied refugee child perceive the exodus? How do the unaccompanied refugee children handle their situation during the flight and at arrival in Sweden?The study is based on a qualitative method and consists in semi-structured interviews with five unaccompanied refugee children aged 17 to 21. The theoretical framework is based on three theoretical concepts; refugee crisis, identity and coping.The study results show that these children are a very vulnerable group, who were forced to be exposed to several losses and traumas.

SammanfattningSyftet med denna uppsats var att undersöka och belysa hur föräldrar till barn och unga med förvärvade hjärnskador i grundskole- samt gymnasieålderåldern, upplever samverkan mellan hemmet och skolan samt skolans stödinsatser.Vi har använt oss av flera metoder i studien genom tillämpning av triangulering med intervjuer, enkäter och skriftliga källor. Intervjuer genomfördes med fyra föräldrar till barn och unga med förvärvade hjärnskador. Enkäter till pedagoger samt ett informationsbrev levererades till fem skolor. Fyra skolor med sammanlagt 16 pedagoger besvarade enkäten. Föräldraenkäterna med informationsbrev skickades till sex föräldrar och samtliga returnerades till oss.

This report deals with an exam report written by Olle Hjalmarsson and Thomas Likar, students at Högskolan i Halmstad. The project was carried out for Haldex Traction AB in Landskrona whose business consist of manufacturing automatic all wheel drive systems (AWD-system). These systems consist of a plate clutch which activates all four wheels of a 4-wheel driven vehicle. An important component in these clutches is the accumulator which basically consists of a piston under the load of a spring which creates an oil pressure with the help of an electric motor used for actuating the clutch.At Haldex difficulties has been experienced regarding the assembly of the accumulator parts due to the small tolerances between the piston and the hole of the accumulator in the cast aluminium housing. Attempts have been made to assemble the parts in existing robot cells.

Introduction: Urinary retention is a common postoperative complication associated with bladder distension. Permanent damage to the bladder affects the patient?s quality of life and may lead to a lifelong inability to empty the bladder and needs of self-catheterization with the risk of urinary tract infection. Bladder distension was classified as the fourth largest health care related injury in Sweden in 2013. Bladder distension may occur before the operation starts and is more common among orthopedic patients.