It generally takes 10 to 12 years for a new drug to hit the market. The pharmaceutical industry invests huge sums in these early stages of research and development. In spite of the rapidly rising research and development expenditures fewer and fewer blockbuster drugs are being developed. Longer lead times and aggressive generic post-patent competition have narrowed the timeframe for the pharmaceutical companies to profit on their investments.In the face of these threats the pharmaceutical industry has developed a battery of strategies to prolong market exclusivity and to maximize return on investment. These emerging strategies are commonly known as Life cycle management (LCM), which actually is more of a concept than a method.

The report examines the factors which may be a contributing cause to the problems that are present when ferritic stainless steel are eddy current tested in a warm condition. The work is carried out at Fagersta Stainless AB in Fagersta which manufactures stainless steel wire. In the rolling mill there is an eddy current equipment for detection of surface defects on the wire. The ferritic stainless steels cause a noise when testing and this noise complicates the detection of defects.Because of this, a study was made of how the noise related to factors such as steel grade, temperature, size and velocity. By observing the signal and with the possibilities to change the equipment settings the capability to let a signal filter reduce the noise level were evaluated.

ABB and Prevas have initiated a collaboration to sell a system to optimize steel industry furnaces, called FOCS. The purpose of this thesis is to investigate possibilities for integrating Prevas FOCS and ABB 800xA.The result of the investigation is used for an implementation of a prototype of the integrated system. The study shows a general method that can be used when implementing two software systems. The prototype of the integrated systems is made with usability principles in mind. This is a very important aspect in order to create a good working environment for the operators of a steel plant.

Atlas Copco Secoroc tillhör en av de tre ledande tillverkarna av bergborr- verktyg. Sandvik Steel har under en längre tid varit Atlas Copco Secorocs enda leverantör av hålvalsat borrstål. Samarbetet mellan företagen har lett till specialiserade produkter och en relation som är svår och tidsödande att bygga upp med en ny leverantör. Relationen har dock blivit påfrestad då leveransprecisionen från Sandvik Steel inte är tillräckligt hög. Den låga leveransprecisionen medför att Atlas Copco Secoroc får svårt att leverera sina produkter i tid.

This M.Sc. thesis is a material application evaluation commissioned by the advanced body engineering department at SAAB Automobile AB. The purpose of the thesis is to evaluate implementation of the innovative sandwich design material Hybrix into an automobile body. Today the most commonly material used in the body is galvanized steel sheets and by shifting material to Hybrix several problematic issues have to be dealt with. Hybrix is an innovative sandwich sheet that inherits thin stainless steel face sheets and a stainless steel fibrous core.

The company Olofsfors AB manufactures drive belts for forest machinery, known as ECO-Tracks, and abrasion-resistant steel and cutting edges for graders, excavators and tractors, known as Bruxite and SharqEdges. Manufacturing these products requires the steel to be heated and molded, then submerged in water and hardened. The water used in the hardening of steel is pumped to the process from pits below the floor and then pumped back to the pit after it?s been used. Since the temperature of this water rises after being used to harden the steel the temperature of the pumping pit needs to be adjusted to maintain its setpoint of 21°C.

Life Cycle Cost, often abbreviated as LCC, is a common tool for comparing the total cost of different alternatives, such as heating and cooling methods. Common heating and cooling methods in Sweden are geothermal energy, district heating and district cooling. This report aims to evaluate how different heating and cooling methods differ from each other while being applied on three different types of buildings, using selected LCC-models. Information about the selected LCC-models wasretrieved from each separate model and its website. Reports and agencies were used as sources for information about the heating and cooling methods.

AbstractThe work will give the picture of what four- and five-year-olds know about the water cycle in nature and in the society. Is there any difference depending on whether a boy or a girl is answering? The work will as well try to describe a picture of how a pre-school could plan their work on a sustainable society, science, and increased gender equality. To answer these questions the information has been received from interviews with children and by studying pre-school?s local plan.    Earlier research on the area of water shows that it is important before working with a new topic to find out what knowledge the children already have, so that the process could be as worthwhile as possible.

The company Olofsfors AB manufactures drive belts for forest machinery, known as ECO-Tracks, and abrasion-resistant steel and cutting edges for graders, excavators and tractors, known as Bruxite and SharqEdges. Manufacturing these products requires the steel to be heated and molded, then submerged in water and hardened. The water used in the hardening of steel is pumped to the process from pits below the floor and then pumped back to the pit after it?s been used. Since the temperature of this water rises after being used to harden the steel the temperature of the pumping pit needs to be adjusted to maintain its setpoint of 21°C.

This thesis has been performed at Uddeholms AB with the purpose to investigate theparameters affecting the formation of inclusions during the manufacturing of a low carbonmanganese-steel.A follow-up, steel and slag sampling and evaluations in microscope have been done for a totalof five heats.The results for each heat have been evaluated in relation to the theory from the literaturesurvey and suggestions for changes in the process to reduce the amount of inclusions whichhave a negative effect on the steel quality have been given.The project extends over a large process where many parameters affect the formation ofinclusions. However, a tendency that a higher addition of alloys seems to increase the totalamount of inclusions before and after the vacuum degassing is seen.The majority of the studied inclusions seem to approach the composition of the top slag aftervacuum degassing. Ladle glaze may cause the inclusions which had a different compositioncompared to that of the slag.A high or low ladleage together with a high argon flow during vacuum degassing seems todissolve particles from the refractory which later on get trapped inside the inclusions.The floatation for two heats has been studied where a short floatation seems to give a higheramount of inclusions in casted material.In machined material so called stringers were found. The main composition of those stringerswas pure alumina. Inclusions with a composition of pure alumina were not found in the liquidsteel, thus the pure alumina inclusions must be formed during the casting.

I denna rapport har det utförts två fallstudier från två olika vindkraftsanläggningar och med hjälp av en utarbetad modell har livscykelkostnaderna jämförts för de två fallstudierna.Resultatet visade att livscykelkostnaden per producerad kWh sjunker allteftersom den installerade effekten blir högre.Kostnadsmodellen som utarbetats och tillämpats för resultaten har visat sig ha hög verifierbarhet då resultaten har varit jämförbara med litterära studier..

The company Olofsfors AB manufactures drive belts for forest machinery, known as ECO-Tracks, and abrasion-resistant steel and cutting edges for graders, excavators and tractors, known as Bruxite and SharqEdges. Manufacturing these products requires the steel to be heated and molded, then submerged in water and hardened. The water used in the hardening of steel is pumped to the process from pits below the floor and then pumped back to the pit after it?s been used. Since the temperature of this water rises after being used to harden the steel the temperature of the pumping pit needs to be adjusted to maintain its setpoint of 21°C.

The last decade has created an increasing pressure on companies to decrease their impact on the environment and to increase their effectiveness of recycling the company?s resources, especially for the steel industry. Companies have also started to realize the economic aspects of an effective internal reverse logistics. In the past the value of an effective internal reverse logistic was something that companies tend to underestimate and there are few academic studies done in this area. The purpose of this essay has been to identify key factors to create an effective in plant storage, transport, sorting and handling of returned steel. From these factors a generalized model for creating an effective return steel flow will be developed.

Digital preservation is a relatively new subject to Swedish archives. Alhough computers have been used for a long time, preservation has been made on paper and stored on shelves. These days a lot of cities in Sweden have investigated how to best secure the digital information for the future through electronic archiving, e-archives. One option is to hand in the information as soon as possible, but to let the producer keep the information ownership yet some time. The idea is to let the producers of the information answer questions and hand out material, since they are more competent on their field.

Suggestion for a new operahouse in stockholm, förslag på nytt operahus i stockholm. Stockholmsoperan..