Determination of serum thymidine kinase 1 (TK-1) activity is used as a tumour marker in both human and veterinary medicine. TK-1 is an intracellular enzyme involved in a salvage pathway of DNA synthesis. The expression of TK-1 is cell cycle dependent and the activity increases markedly after the G1 to S transition in the cell cycle and then declines rapidly in G2. The pronounced proliferative activity in tumour cells result in a higher TK-1 enzyme activity within the cell. The fact that the increased TK-1 activity can be measured in serum makes TK-1 a useful marker in diagnostics of neoplastic diseases and it provides information regarding prognosis and treatment effectiveness. In human medicine a radioactive based test is used to determine the TK-1 serum activity.

I denna kandidatuppsats avlägsnas organiska föroreningar från vatten genom användning av textilier, vars yta belagts med nanopartiklar utav ämnet titandioxid. När titandioxid belyses med UV-strålning sker en fotokatalytisk reaktion, vilket i sin tur bryter ned bland annat bakterier och organiska färgämnen. I hopp om att finna ultimat vidhäftning mot textil passande titandioxid har olika typer av beläggningar studerats; akrylbaserade, sol-gel och slutligen en hybrid. Dessutom har fem olika konstruktioner av textila bindningar jämförts i syfte att undersöka dess påverkan på den fotokatalytiska effekten. Förorenade vatten är ett stort problem, både i utvecklingsländer och i industriella sammanhang.

Uppsalahem is the leading housing corporation in Uppsala with its over 160 real estate properties. Uppsalahem is owned by the municipality of Uppsala, which has a climate and energy goal that aims for 100 MW of solar energy to be installed in Uppsala by 2030. The 100 MW goal, combined with Uppsalahem?s environmental policy, is a strong incentive to investigate the possibility of installing PV modules on the many available roof areas that Uppsalahem possesses. The objective of this thesis is to create a foundation for future decisions regarding PV systems for Uppsalahem.

This thesis within the field of Integrated Product development at the Royal Insitute ofTechnology, performed at Primary Development Dishcare at AB Electrolux, is supposed to finda solution to enhance the hygiene inside an Electrolux dishwasher. The outcomes of this thesisare functional prototypes to evaluate the efficiency of disinfection by the use of Ultra VioletLight and Ozone.The thesis has followed Electrolux Primary Development process, with delivarables andcheckpoints.Ultra violett light with a wavelength of around 264 nm penetrates through the cell wall ofbacteria and micro organisms and causes a molecular rearrangement of the cells DNA. Thisprevent the bacteria from reproducing and it is considered dead. Commonly used UV-C lampstransmits the wavelength 254 nm which is very close to the optimum for germicidal action.A competitive brand have reacently launched a dishwasher claiming to achieve greaterdisinfection with an UV feature. This dishwasher was tested during the thesis and proven tohave a very low effect on the hygienic result.Two prototypes were devolped and tested for UV disinfection of dishware.

During the milling of Sandvik Coromant?s world leading Drill with replaceable inserts,the CoroDrill880©, burrs appear around the milled surfaces. The burrs are removedusing different methods, one of which is deburring with special brushing machines thatare integrated into milling cells. The machines of the type Sinjet, use a Siemensguidance system. The deburring results are not satisfying and manual deburring isrequired afterwards.

The company Sol & Energiteknik wanted to examine the possibility to make a standardhouse totally energy independent. Based upon this I have, during the spring of 2007,examined the possibilities available at the market today through litterature studies, contactwith several companies and reading reports at the internet.The first thing to examine has been to determine the energy consumption for a standardhouse, and find out if there are better technologies to be used for energy conservation.My conclusion in this matter is that there are possibilities today for building a house moreenergy efficient.When I had reached the point at which my design for the house was decided, I also hadto choose the different products to use to produce energy as well as to store that energy.To produce heat and electricity to the house I decided to use a wind turbine and a solarwater heater.The most difficult part of designing a house that is energy independent is that theproduced energy must be stored somehow. Storing the heat is relatively easy beacuse theheat can be stored in a large water tank. The electricity is a bigger problem beacuse itmust be stored in batteries, which today are too expensive to be used in a standard house.In the future producing and storing hydrogen might be used to produce electricity, buttoday that technology is both expensive and not tested enough.My final conclusion is that a standard house can not be built to be totally energyindependent today, unless it is very expensive to connect the house to the electricitynetwork. As an alternative solution I came up with a proposal for a house which isconnected to the electricity network and have some amount of own produced energy.This house prooved to be a good investment if you choose to build it today, and it couldbe a very good investment in the long run beacuse energy prices increase every year..

With the climate change issues growing in importance on the social agenda, the field of urban masterplanning is of no exception when it comes to minimizing the carbon footprint in a variety of projects. The aim of this thesis has been to prepare the Carbon Critical Masterplanning tool, a software plugin for carbon dioxide emissions assessment developed by Atkins, to be used in Swedish conditions. The main targets were to improve the areas of the tool associated with energy conversion and renewable energy sources, and to test the tool in a real case. A planned construction of a new campus in Albano, Stockholm was chosen for the pilot study. A 3D model was built in the tool and the carbon footprint was calculated for a variety of combinations for energy supply to the future area.

Since early civilization, herbal tea has been used as remedies for an abundance of different diseases. Among these herbal remedies, peppermint (Mentha piperita) was used for its effect on bowel related ailments. Even though peppermint was not described until late 17th century, it has been used since 1000 years before Christ by the Egyptians. In present day it is still considered a remedy for stomach pain etcetera, and much of the recent research is concentrated on the positive effects of peppermint on pain and bowel diseases. A large section of the research is also reviewing positive effects of peppermint on cancer, allergy and also on its potential as antibacterial agent.

The purpose of this paper is to understand the climate of the street and how it can be modified to better meet the needs of the street and the user groups. At the same time the conditions of the street and its surroundings also has to be taken into account. To accomplish this it is necessary to have a broad knowledge of the climate conditions in the city. Therefore an overview of the climate elements and how these are modified in the built-up areas are given. The part of the paper which deals with the city climate has a global approach to be able to give an as complete picture as possible.

This thesis examines the environmental benefits resulting from the choice of environmental certification scheme, with focus on energy. This was carried out by studying the measures that were implemented as a result of the certification of Sweco's three largest office buildings in Stockholm, Gothenburg and Malmö. The office property in Stockholm has been certified with the Swedish Environmental Building, Gothenburg with the British BREEAM and Malmö with the U.S system LEED.The results from the study indicate that an environmental certification can reduce the energy consumption by up to 59 percent and the water consumption by 20 to 66 percent. However; the interviews, literature study and simulations in MATLAB indicate that the size and scope of these environmental benefits depend on several identified factors: the type of building and its conditions, system selection, grade level, the choice of indicators, the ambition of those involved and when in time the certification process begins. The comparison between Environmental Building, LEED and BREEAM showed that Environmental Building for the office property in Stockholm gave the largest environmental benefit in terms of reduced energy consumption thanks to several large measures.

Thymidine kinase 1 (TK1) is an intracellular enzyme involved in ?the salvage pathway? where the uncomplete parts of DNA are transformed into DNA precursors. The expression of TK1 is cell cykle specific, with the highest level during S-phase when DNA-synthesis is most active. One kind of TK1 is present in serum and an increase in TK1 activity in serum is due to either the level of DNA synthesis in the body or the number of cells dying in a state of replication. This can be used and is used as a marker for prognosis and evaluation of treatment in human patients with leukemia and lymphoma.

This thesis includes an energy survey of the Herrgården pre-school, which has a modern heating- and ventilation system, and a comparison with Östers pre-school which has an older system. An energy survey of Östers pre-school has already been done by a group of three students and all the calculations and values have been collected from that survey. As of today, both pre-schools are heated thru district heating. It will be much easier to make smart and feasible energy-saving-measures by first conducting the energy survey.Herrgården pre-school in Gävle houses 81 children, therteen teachers, one cleaner and one cook. It was finished in the middle of 2009 and the staff has been very pleased with the in-door climate.

Bergvik Skog is one of the leading forest companies in Sweden who use airborne laser scanning for forestry information. They utilize laser data retrieved by the Swedish National Land Survey to describe the forest holdings and facilitate planning for thinning and final felling operations. However, the possibility to identify stands with clearing needs by using laser scanning data has not been tested in a large scale. The data used in the current study are field data from The Swedish National Forest Inventory in combination with laser data from the Swedish National Land Survey acquired in 2009. The collected data is used to find one or several laser variables that best describe the relationship of the field measured samples with clearing needs.

This is a literature study in which I investigate if there are scientific studies that form the basis of the Swedish dog world views concerning the spaying of bitches. The positive impacts are said to be reduced problems with pseudopregnancy, reduced risk of pyometra, reduced risk of mammary and uterine tumors, an earlier cease of bone growth, a more active and happier dog and a bitch who is more tolerant of other dogs. The negative consequences are said to be urinary incontinence, increased aggressiveness, lower metabolism and the increased risk of obesity, a more lethargic individual and altered coat.There are studies indicating that spaying reduces behavioral problems associated with heat and pseudopregnancy. Assuming no ovary tissue persists after the procedure, and there is no progesterone production, the risk of pyometra decreases. Early spaying, before the first heat, reduces the risk of mammary tumors.

This thesis includes an energy survey of the Herrgården pre-school, which has a modern heating- and ventilation system, and a comparison with Östers pre-school which has an older system. An energy survey of Östers pre-school has already been done by a group of three students and all the calculations and values have been collected from that survey. As of today, both pre-schools are heated thru district heating. It will be much easier to make smart and feasible energy-saving-measures by first conducting the energy survey.Herrgården pre-school in Gävle houses 81 children, therteen teachers, one cleaner and one cook. It was finished in the middle of 2009 and the staff has been very pleased with the in-door climate.