Amyotrophic lateral sclerosis is one of the major neurodegenerative diseases, causing an ascending paralysis that usually kills the patient within a few years from disease onset. The motor neurons show aggregates of proteins which in approximately 20 % of cases of the familial form contain mutated SOD1 protein. Trehalose is a disaccharide which has been shown to reduce protein aggregation and increase viability in cell models and alleviate symptoms in animal models of several neurodegenerative diseases associated with protein aggregation. When given orally to the SOD1G93A mouse model of ALS, trehalose failed to slow down the disease progression, which has led to questions about the uptake and distribution of the molecule in this mouse strain. The aim of this study was to investigate whether significant levels of trehalose reach the central nervous system of the SOD1G93A mouse after oral administration. This was performed by a trehalose assay of the brain of trehalose treated animals. A glucose assay was optimised for use in small samples of brain lysate after the digestion of trehalose into glucose by trehalase, and the difference in glucose concentration before and after digestion represented the trehalose level.

The aim of this essay was to study how the communities work with groups as a support to children with addictive parents, and to increase my understanding of the groups meaning as a support. My main questions have been: How are the child group sessions formed? What kind of experience does the group leaders have regarding their functions? The study is a qualitative investigation that has been turned to prefessionals in the subject area and  is based on 6 interviews and secondary sources. The material has been analyzed from a narrativ theory as well as a salutogent perspective. Research shows that children growing up in an addictive environment often have decreased psychological health and are overrepresented amongst those who developed a future addiction.

This paper deals with the food economy in the Mesolithic ? Neolithic settlement Sjöholmenfrom excavation in 1961 lead by Ingeborg Tillander. This material has been compared withthe material from Ringsjöholm and Ageröd V since these places are situated near each other.The paper has three different parts there we go deeper in to birds, beaver and small vertebrae,fishes and carnivores. Another large part in the paper are taphonomic processes, faunal historyand previous research about Sjöholmen..

This essay examines the olfactory reading as a possible way to make sense of a fragmented novel, in this case Sara Stridsberg?s debut Happy Sally (2004). Through close reading, the essay identifies the source of the smells, who perceives it, and how this is portrayed in the text. The smell?s position in the text is understood in relation to Maurice Merleau-Ponty?s phenomenology, where the body, as created in the literary text, is considered as a source of knowledge.

This paper describes the work done trying to diminish the noise present in the signal from an IR-detector. The project was aiming towards two different kinds of applications; heat protection and presence detection. The hypothesis was that the signal-noise ratio would decrease if a filter and a proper installation were used for the detector. Some experiments were executed to determine what kind of filter were the most suitable for each application and how these could be installed. After executing the experiments and evaluate the results we recommend to use a specific filter for each application.

Background: Small businesses are key participants in the growth at the Swedish market, partly for the labour opportunities, the technology and economic development. These companies should get resources to grow, both political and economic resources. The medtech companies in an introduction and expansion phase meet with problems concerning the financing of their growth. Key participants whom offer financing are Venture Capitalists.Purpose: The purpose of this study is to examine Venture Capitalists demands on medtech companies in an introduction and expansion phase. A comparison between the demands and how well medtech companies achieve them will be done.

Cardiovascular disease is the leading cause of death in the Western world. For persons who have had a myocardial infarction the following rehabilitation and the group training, which is a part of this, are very important. The cardiac rehabilitation is designed to limit the physiological and psychological effects of cardiovascular disease. Purpose: This study aimed to examine how patients with cardiovascular disease experienced group training in relation to the International Classification of Function, Disability and Health, ICF. Method: A qualitative interview study was performed according to Malterud, inspired by the Grounded Theory method.

The purpose of this study was to illuminate the everyday work of school counsellors in the City of Stockholm with a gender perspective by studying the school counsellors ? talk about masculinity and femininity. The aim was to reach an understanding of how parts of the counsellors everyday work are influenced by gender through the perspective of the school counsellor. The study was conducted using qualitative methods. Six school counsellors, five woman and one man, were interviewed.

Title: Older people's experiences of exercise training: a survey based on a descriptive design.Course: Public Health: Theory and method of application and degree, 30 credits. University of Gävle, health education program.Author: Helena AnderssonPurpose: According to earlier research the western population is aging. This may affect, the older peoples`s physical disability in one form or another. The consequences may be that the need off care can increase. However elderly can prevent a variety of age-related diseases by being physically active.

The aim of this study was to investigate whether the Swedish Institute of public health care uses paternalistic information in their alcohol publications. My intention has also been to examine to what extent the paternalistic information is being used. This is determined simply by how frequently paternalistic information is found in the publications. I chose to analyse five publications that contain alcohol related information and had a clear motive. My results show that all five publications use paternalistic methods with the intention to change readers, or people in their surroundings, alcoholic behaviour. Though this is quite a small essay, I have suggested extended research of the subject ? preferably of all 176 alcoholic publications presented by the Institute of public health care..

In this paper, a small business network with around 30 users is analyzed with respect to security, performance and usability. Based on this analysis, two suggestions on how to solve the problems listed are given. The first suggestion focus on keeping a low budget, while the other tries to deal with the problems more thoroughly. One advantage of the first suggestion is, in addition to not straining the company's budget more than nessecary, it does not involve too great changes in the way the network is used and administered. On the other hand, the smaller budget leads to certain compromises, and there is a risk that similar problems occur again if, for example, the company would grow.

This paper discusses normativity in selecting musical phonograms in public libraries. The purpose is to gain an increased understanding of music activity in public libraries. To do this I have interviewed five music librarians about their visions, ideals and goals with their work. The questions discussed concern ambitions with the music activity and how to keep up to date with current record releases. For the theoretical frame I use two kinds of material.

Sahlgrenska Academyat University of GothenburgDepartment of Internal Medicine and Clinical NutritionAbstractTitle: Is pricing a way to affect share of fruits and vegetables in a diet?Author: Maria PopovSupervisor: Heléne Bertéus ForslundExaminer: Ingrid LarssonProgramme: Dietician study programme, 180/240 ECTSType of paper: Examination paper, 15 hpDate: May 23, 2013Background: Fruits and vegetables (FV) are important for health, including occurrence of diabetes, obesity and cardiovascular diseases. Said diseases cause most cases of illness and death in high-income countries. Only a small part of the population achieves the FV-intake goal, so a higher FV-intake is desirable. Besides general information campaigns there is another method of influencing what people might buy.Objective: To examine whether different pricing is connected to FV-intake or ?purchase.Search strategy: Databases PubMed, Scopus and Summon were searched with ?vegetable consumption", "price/pricing policy" and "food choice? in different combinations.Selection criteria: Studies performed after year 2000 on at least 18 years old persons from North America, Europe or Australia, examining changes in FV-price and -purchase.

In today´s labour market, men and women are segregated, both vertically and horizontally. Exceptions to the rule of gender segregation are few. There is, however, one managerial group where women and men are equal in numbers: school principals. In a short period of time, the distribution in terms of sex among principals in Sweden has changed dramatically. How does gender equality in numbers affect gender equality in a qualitative sense? That is the focus of this thesis.

Like many small-time companies there is a need to improve the flow of materials at HSP-Gripen AB. The company develops and manufactures hydraulic-powered grapples for the machine- and forest industry. By mapping the material flow in the current production and gathering necessary data, suggestions on how different parts of the production could be controlled is presented in this dissertation. This has been achieved by the study of relevant scientific literature. The suggested ways of controlling the production consist of 2-bin systems, hybrid material flow system as well as a cyclic product-planning.