Since several lifestyle diseases are associated with obesity much research is carried out within the area. Researchers have found that oxidation of fatty acids within the body?s cells may give rise to peripheral signals which regulate food intake, but it is still unclear where such a mechanism takes place. Although much evidence suggests that it is the hepatocytes in the liver that send signals regulating food intake, some researchers have begun to question this theory. Instead they argue that the mechanism takes place within the enterocytes since they are well localised in the gut for such assignment.

 Genotyping can be used to link genetic variation among individuals to certain diseases or conditions. Some known disorders and states that are dependent on single nucleotide polymorphism (SNPs) are lactose intolerance, venous thrombosis, hereditary hemochromatosis and the difference in sensibility among people to metabolise drugs.In this project a new kit, TaqManÒ Sample-to-SNP KitÔ for extraction of DNA and preparation of the extract for genotyping with real-time PCR and allelic discrimination, was evaluated. QIAamp® DNA Blood Biorobot® MDx Kit was used as the reference method.The purpose of the comparison was to find a method that makes DNA extraction from blood samples cheaper and faster, but with the same reliability as the reference procedure.The results of the evaluation showed a complete agreement of the genotype results between the methods tested, which means that the new method was as reliable as the reference method. The costs of reagents and material would be reduced with 52% if the new method is adopted, that alone would result in a cost reduction of 144 000SEK a year with a sample volume of 650 samples/month. The time for DNA extraction would also be reduced with the new procedure. .

Syftet med denna litteraturstudie är att belysa omvårdnaden för familjer till barn med hjärtfel ur ett familjeperspektiv. Vården av hjärtsjuka barn och ungdomar kräver en kunskap om dessa sjukdomar inte enbart hos sjukvårdspersonal inom den högspecialiserade barnkardiologin utan inom ett flertal andra specialiteter. Studien omfattar sjuksköterskans omvårdnad av familjer, förberedelser för hemgång, samarbetet mellan olika yrkeskategorier, familjens reaktioner vid denna krissituation och de bearbetningsmodeller som finns till förfogande för att underlätta bearbetningsprocessen. Vidare forskning inom detta område är nödvändig. The purpose of this study is to illuminate the care of families to children with heartdisease from a familyperspective.

Abstract      Background: Stroke, caused by a blood clot or a bleeding in the brain, is one of the large endemic diseases in Sweden. The symptoms are very individual and depend on where the stroke is located. The nurse is a key person due to the importance to individualize the rehabilitation of the patient. The consequences after a stroke are not only visible functions reductions but also cognitive and practical problems. Stroke often leads to extensive changes in life, and individuals who get a stroke have to adjust their daily life. Aim: The aim of the study was to describe individuals? experiences of changes in daily life, one year or more after a stroke. Method: An inductive, qualitative approach was used.

Stroke is caused by a bleeding or infarct in the brain and is one of the most common diseases in Sweden today. The purpose of the study was to evaluate if Ronnie Gardiner?s Rhythm Therapy (RGR-therapy) has any effect, regarding motor control and the subjective experienced health related quality of life, on people who have been affected by stroke. The examination group consisted of eight people. The intervention consisted of RGR-therapy once a week during a period of nine weeks.

BACKGROUND: Chronic Obstructive Pulmonary Disease (COPD) is a slow progressive disease affecting the family caregivers by limiting their lifestyle. Subsequently the situation can be experienced as stressful for both the afflicted and the relatives. To easier understand the needs of the caregivers of family members suffering from COPD have, it is important to get an insight into their experience of every-day life, so that medical staff can help, support and promote their health according to their needs. AIM: To illustrate caregivers? experiences of living with a family member suffering from Chronic Obstructive Pulmonary Disease.

Cows are ruminants and they need fibers in their feed and sufficient eating time to function psychologically and physiologically. Many of our cows don?t get enough forage and too much concentrates, which given in the wrong way may cause health and behavior problems. Too much concentrates at once makes the pH in the rumen sink and this may cause decreased fiber utilization since the microbes in the rumen are negatively affected by this. The cow may also get serious problems such as laminitis and abomasal dislocation.

The workplace is perhaps the most developed arena for prevention of diseases and injuries among employees. In addition, according to the Swedish Work Environment Act, the employer is responsible to address physical and psychosocial risk factors. Moreover, many employers use health promotion, primarily related to individuals and their ambition to maintain or improve health, for example through dietary means and exercise. The aim of this study is to investigate health inspirers in municipal activities and their perceived support and motivation in work related to health promotion at the workplace. A qualitative method was chosen where six health inspirers within Ludvika kommun were interviewed.

Our companion animals can, with or without symptoms, carry infectious agents which have a potential to induce diseases in man, so called zoonoses. An immune compromised person has an increased risk of becoming infected by various agents, and thus also has an increased risk to become infected by one?s own companion animals. A study was carried out within the veterinary program at SLU, Sweden, based on a questionnaire answered by 31 physicians, 31 veterinarians and interviews of 30 immune compromised persons in Sweden. The study investigated the following questions: Which zoonoses do physicians and veterinarians consider to be the most important to inform immunecompromised persons about? How are immunecompromised persons being informed by their physicians about the risk of catching zoonoses from their companion animals? How are the owners of zoonosis-infected animals being informed by their veterinarians about zoonoses? Does veterinary medicine and human medicine communicate about zoonoses, in order to take the best care of immunecompromised persons in contact with animals? The results of our study imply that: - Physicians and veterinarians differ about which zoonoses immunecompromised persons should be informed about. - Only oral information is passed to immunecompromised persons and animal owners.

This study deals with work environment from a legal perspective. The study includes legislative history, legislation today and one empirical study. The legislation that concerns work environment (health and safety) in Sweden today is found in the Swedish Work Environment Act (WEA), the Work Environment Ordinance (WEO), Provisions issued by the Work Environment Authority, related legislations and also collective agreements. The WEA, passed by the parliament in 1977, came into force on the 1st of July 1978 and it defines the framework for Provisions issued by the Work Environment Authority, which is an authority superintended by the Swedish government. These Provisions contain more detailed stipulations and obligations with reference to the working environment.

An ageing population calls for enlarged needs of care and treatments that is followed by an increased demand on social and medical care. Present organization and structure are not adjusted to these new requirements. Due to this fact, necessary alterations ought to be made between and within the different institutional and non-institutional care actors. This work should be settled locally. In this study, the aim was to describe "Chealth care nearby" as being a new standard of care as well as investigate its significance in the co-operation and collaboration between different care actors.

The state of health in Sweden demonstrates a high average length of life at the same time as diseases, due to luxurious living, grew into more and more widespread public health problems. Finding out that information is not enough to get man to live healthy has been conducive to a pedagogic based health education. An illustration of such an education is Public health pedagogy at the University of Kristianstad. The question is, does this education correspond to the new claims that society lays to health work? Our purpose was to throw light upon how individuals, qualified as public health pedagogues, look upon their work on one hand and how different clusters of thought from their study programme are conceived as activated in their professional exercise on the other.

This paper aims to, through a literature review, examine how to best design and adapt calf huts to meet the calf's physiological requirements and reduce the infection pressure for enteric and respiratory diseases. It illuminates how the calf relates to different temperatures and climate, which temperature control mechanisms it uses and its ability to perform these regulations, as well as providing a summary of the past decades´ research on the calf huts housing system. These two theory chapters, along with a concluding discussion, provide a better understanding of how to, especially in temperate climates, design the most suitable calf hut, which cater to the calf's both thermal comfort and physical health. The literature suggests that the calf's own temperature control works well to counteract the temperature outside the desired range, and that one of the most important factors rather is ventilation of a calf hut, which reduces moisture and pathogens. The conclusion of this paper is mainly that there is not an obvious way to place and construct a calf hutch and that most design principles contribute to both positive and negative effects simultaneously.

Background: Inflammatory bowel disease (IBD) is an umbrella term for ulcerative colitis and Crohn's disease. These are characterized by a chronic inflammation of the intestinal mucosa. Living with chronic illness meant that life changed significantly. Quality of life was affected for these individuals and was stressful in their lives. Aim: The aim was to describe the experiences of living with inflammatory bowel disease. Method: A qualitative literature review was chosen to analyze articles that were related to the aim of this study. Results: Based on the chosen articles five themes were created; Commuting between hope and fear, symptoms of the disease and medication become everyday focus, struggling with  the new identity, desire to control the disease- do I control my illness or does it control me and social relationships are affected. Conclusion: Inflammatory bowel disease is a distressing disease and can cause limitations in social life due to lack of knowledge by others about the disease. The affected felt a loss of control in their life due to the difficulty in managing the symptoms.

The development of quantitative, real-time PCR (qPCR) combined with the mapping of the canine genome opens new possibilities in veterinary medicine. This method provides a quick and accurate quantification of the expression of a specific gene at a given point in time and thereby also information of how the gene expression for a certain protein is influenced by various conditions and diseases. One possible area of application is identifying bio markers for cancer. Recently the protein serglycin (the core protein of an intracellular proteoglycan) was found to act as a selective marker for the disease acute myeloid leukemia in humans (Niemann et al, 2007). Serglycin is produced by most hematopoietic cells, although mast cells account for the largest amount of serglycin.