Purpose The purpose of this study is to evaluate the treatment results and adverse drug effects for 14 dogs receiving a new paclitaxel preparat named Paccal vet. The evaluated dogs are chosen to enter a pharmacogenomical study. Therefore, this paper intends to give an introduction to pharmacogenomics. Finally this study also aims at finding the homologue genesequenses in dogs to seven genes that are important for metabolism of paclitaxel in humans. Materials and metods The dogs went through 2-4 cycles of paclitaxel treatment, they received a new water-soluble formula named Paccal vet, at dosages of 100-150mg/m2. Treatment results and adverse effects are listed for each dog in table 1.

Service branding is a subject that has been excluded from the traditional branding theory. Our main purpose with this paper is to distinguish what characterizes service branding. To do this, we have looked in to both service marketing theory as well as branding theory. We have also looked at the existing theory concerning service branding. Six qualitative interviews have been performed to explain what characterizes service branding.

As self-service technologies become more common in service provisions, a deeper understanding is needed of how customer satisfaction is affected by automated service encounters. Drawing from theories of customer satisfaction, human interaction, and the dynamics of complex service provisions, the differences between automated and interpersonal service encounters in the initial part of a service provision are examined in terms of customers? evaluation of the service encounter itself, overall satisfaction, as well as the service encounter?s impact on global evaluations and evaluations of other non-dependant service encounters. The study was performed on people travelling by air on Swedish domestic routes. Passengers were asked to evaluate the airline?s performance on different attributes of the air travel they had undertaken, as well as to form an overall evaluation of the service.

This article presents a retrospective case study combined with a review of the current literature concerning canine gestational diabetes. A total of 14 cases have been collected from six different clinics in Sweden. There are few previously published reports on canine gestational diabetes. Gestational diabetes is a disease that rarely occurs in pregnant bitches. The condition is due to the rise of progesterone that occurs during the estrus cycle.

Measurement of plasma concentrations of natriuretic peptides have been suggested to be of diagnostic and prognostic value in canine cardiac disease. In several previous canine studies, however, a considerable overlap between investigated groups has been identified. A reliable natriuretic peptide test for use in clinical practice requires establishment of reference values for natriuretic peptides in healthy dogs and cut-off values for subclinical disease as well as for clinical signs of congestive heart failure. Numerous physiological, pathological and pharmacological factors, aside heart function, may influence concentration of natriuretic peptides. A potential effect of dog breed on natriuretic peptide concentration has been suggested but has, to our knowledge, not previously been specifically studied.

Problemformulering: Går det att uppnå en signifikant återkommande överavkastning samt riskjusterad överavkastning i förhållande till den svenska aktiemarknaden genom systematiskt följande av investeringsstrategin ?Dogs of the Dow??Syfte: Syftet är att undersöka huruvida teorin ?Dogs of the Dow? är applicerbar på den svenska aktiemarknaden i sökandet efter en signifikant återkommande överavkastning i förhållande till marknaden. Med detta hoppas det finnas en positiv differens av den riskjusterade överavkastningen gentemot index.Metod: Studien samlar in primärdata för empirin via SIX Trust, SIX Edge samt från Riksbankens hemsida. Sekundärdata härstammar från vetenskapliga artiklar uthämtade från främst JStor och EBSCO Host. Även studentlitteratur, tidigare studier utgör sekundärdata.

The effects of dexmedetomidine and butorphanol sedation on skin reactivity during intradermal testing in healthy dogs were evaluated. The effects of dexmedetomidine and butorphanol were compared to medetomidine, a sedative agent having scientific proof of not interfering with skin test reactivity, in a randomised, double blind, cross over study performed on 8 adult dogs. The dogs were sedated with medetomidine (Domitor vet.®, 0,01 ml kg-1) intravenously, or dexmedetomidine and butorphanol intramuscularly (Dexdomitor vet.®, 0,01 ml kg-1; Dolorex vet., 0,01 ml kg-1) after which they received intradermal injections of positive control solutions (histamine 0,1 mg ml-1, 0,05 mg ml-1, 0,025 mg ml-1), a negative control solution (0,9 % NaCl) and allergen extract (Dermatophagoides farinae, Cladosporium and Artemisia vulgaris). After a wash out period the trial was repeated with a reversed sedation protocol.Skin reactivity (wheal size, induration and erythema) and quality of sedation (immobilization, response to stimuli and injections as well as over all working conditions) were evaluated. The combination of dexmedetomidine and butorphanol provided reliable, good sedation and analgesia without adverse effects.

The bark from prehistory ? an osteological analysis on dog bones from the Stone Age settlements of Hemmor and Gullrum at Gotland and a theoretic study of the secular and sacred roles of the dog during the Neolithic.Dog bones from two Pitted Ware Culture (around 2500 BC) settlements, Hemmor in När parish and Gullrum in Näs parish/Havdhem parish, at southern Gotland, Sweden are analyzed. The analysis contains a study of age, withers height and size estimation as well as skeletal changes and pathologies. The attempt of the analysis is to highlight the secular and sacred role of the dog during the Neolithic at Gotland. The dog bones were collected during excavations in the years 1890 and 1903 and were found across the entire surfaces of the settlements.Although there were no specific dog breeds during the Stone Age, the dogs at Hemmor and Gullrum show a wide range of size (withers height spans from 39,74 cm to 56,47 cm) and may therefore have been used for different purposes depending on their size.

Malassezia otitis in dogs is a common cause of visit to a veterinary service. In otitis externa due to Malassezia overgrowth the dog has a higher number of yeast organisms and/or a local inflammatory response to the micro organism. Common clinical signs include pruritus, erythema, swelling and increased exudate production. Clinical symptoms and results from cytology of ear swabs from the ear canal is the mainstay for diagnosis. Any underlying condition has to be identified and corrected to avoid relapse. The treatment options for infective otitis externa are based upon topical administration of eardrops containing antibiotics, steroids and antifungals.

The prime aim of this thesis was to investigate whether high or low iodine intake during certain periods of life was, or was not a strong risk factor for the development of canine lymphocytic thyroiditis (CLT). And secondly, if a high or low selenium intake in a combination with high or low iodine intake also may have an influence on that risk factor. To investigate this, a dietary questionnaire was sent out to dog owners. The dogs were selected from an ongoing genetic study of CLT. The questions investigated brand and type of feed during different life stages (puppy, junior and adult) and also if there were any use of dietary supplements.

Syftet med föreliggande litteraturstudie var att beskriva på vilket sätt licensierade vårdhundar kan fungera som ett komplement i omvårdnaden av barn med autismspektrumtillstånd. Syftet var också att beskriva kvaliteten av artiklarna utifrån den metodologiska aspekten urval. En litteraturstudie med deskriptiv ansats genomfördes utifrån två artiklar med kvalitativ ansats, två artiklar med kvantitativ ansats, fyra artiklar med kvalitativ ansats och kvantitativa mätningar, samt två artiklar med kvantitativ ansats och kvalitativa inslag i form av observationer. De inkluderade artiklarna hade publicerats mellan åren 1989 och 2013. De databaser som användes för artikelsökningen var Academic Search Elite, Cinahl och PubMed med sökorden: Dogs, Child, Autism Spectrum Disorders, Animal-assisted, Service dogs, Autism samt Therapy Dogs.

Castration of dogs holds many reasons and opinions, therefore methods, traditions and rea-sons vary. The approaches have during time changed from mostly surgical castrations to also including hormonal treatments. Castration is used to control the dog's reproductive abilities, for medical reasons and to possibly rectify problems of behavioral nature. How common a particular method of castration is in a country is highly dependent on the country's traditions. In Sweden it is most common with castration for medical reasons, such as possible elimina-tion of diseases, for example, benign colorectal tumors.

The histiocytic diseases are generally rare in dogs and not much is known about the disease. The disease complex that includes both a reactive form and a tumour form, is however common in certain breeds, among them the Bernese Mountain Dog. As the literature is very limited on the subject of histiocytic diseases, my aim with this thesis has been to gather current knowledge of these diseases. I have also attempted to estimate the frequency of the diseases among the Swedish Bernese Mountain Dogs and investigate if they appear to be more common among certain families..

Idiopathic pulmonary fibrosis (IPF) is a chronic respiratory disease with an estimated incidence of 3-6 cases per 100 000 inhabitants in Sweden. There is no cure for the disease, which inevitably leads to death. A similar disease has been found among terrier dogs, with an especially high prevalence in the West Highland White Terrier (WHWT). Dogs with pulmonary fibrosis become lethargic with exercise intolerance, and in some cases they develop cough and respiratory distress. This thesis gives a brief review of the field of pulmonary fibrosis and presents a method for analyzing surfactant proteins in bronchoalveolar lavage (BAL) in the dog.

Aggression is a normal part of a dog?s behaviour repertoire and has always been an evolutionary relevant behaviour. Even if aggression in some contexts is relevant, it is one of the most common problem behaviour reported by dog owners. It has been discussed if some breeds are more likely to show aggression and therefore should be banned. On the 1st of January 2008 a new act was enforced by the Swedish government giving the police force greater authority in decisions to apprehend and euthanize dogs if they after an appropriate evaluation of the dog?s temperament think it is necessary.