Mast cells have for a long time been known to accumulate around tumors (Maltby et al., 2009). Studies show that they may be important and sometimes essential in tumor angiogenesis, tumor growth and metastasis of tumors (Soucek, et al., 2007; Xiang et al., 2010). In an expression array study (Wensman et al, submitted manuscript) performed on mouse mast cells exposed to tumor conditioned medium, the gene 4-1BB was among the most up-regulated genes compared to control medium. 4-1BB codes for a membrane receptor protein of the tumor necrosis factor superfamily and has been shown to be important in T cell regulation in tumor diseases. This study was performed to investigate if human mast cells up-regulate 4-1BB when they get exposed to tumor conditioned medium.

To date, the genus Helicobacter consist of 26 different species and even more species are yet to be characterized. Helicobacter has been detected in connection with diseases in the liver and pancreas in humans and animals. Helicobacter spp. are gram negative, curved, S-shaped or spiral shaped bacteria. They are microaerophilic and have flagella that make them motile. Helicobacter, present in the gastric mucosa neutralize the gastric acid through production of urease that hydrolyses urea to ammonia and bicarbonate.

Försämrat immunförsvar och ökad risk att drabbas av bakterie- och virusinfektioner förekommer hos patienter med blodsjukdomarna multipelt myelom, Waldenströms makroglobulinemi samt hos vissa patienter med blodsjukdomen monoklonal gammopati av oklar signifikans. Infektionerna kräver ofta antibiotikabehandling och behandling med antivirala medel. I dagsläget är det svårt att förutsäga vilka av patienterna som kommer att drabbas av svåra och ibland livshotande infektioner. Därför ges många av patienterna förebyggande antibiotikabehandling.I studiens början sattes en enzyme-linked immunosorbent assay (ELISA) för detektion av antikroppar mot Moraxella catarrhalis upp. I studien undersöktes om antikroppstitrar i serum mot bakterien Moraxella catarrhalis var lägre hos patientgrupperna än hos friska kontrollpersoner i samma ålder och om variationer förekom mellan patientgrupperna samt hur kontrollgrupper i olika åldrar skiljde sig från varandra.

This thesis investigates and analyses the social media strategy of eight companies. How the companies measure and evaluate their activity and investments in social media channels in general, and Facebook in particular is studied through qualitative interviews. The findings are then compared and analysed. Findings indicate that companies' social media presences to a large extent are dependent on individual employees with high levels of interest for the area and that companies that have integrated social media into their others operations see more value from their efforts..

In modern dairy production the milking frequency is increased in some herds due to introducing of automatic milking systems or the farmers decision to milk high producing dairy cows more than two times a day. With more frequent milkings the milk yield increases while the content of fat and protein decreases. However, how the composition of protein is influenced is not fully evaluated. The purpose of this study was therefore to see if a higher milking frequency had any impact on the milk production and especially on the protein composition. This study was conducted as a half udder experiment.

The purpose of this study was to gain greater knowledge of how preschool teachers and children using an experimental- and activity box in biology. To find this out, I have used the participant observation method and semi-structured interviews since my study is qualitative. The result of the work led to a greater understanding of the biologybox. It was shown that preschool teachers' involvement is very important for children and that the biologybox contained good and inspiring materials. Although educators desired that there was more material to choose from as well as the usage time of the biologybox should be longer than 3 weeks..

Rift Valley Fever (RVF) is a disease caused by Rift Valley Fever virus (RVFV), which is an arbovirus. An arbovirus is a virus that is transmitted by an arthropod vector, in this case a mosquito. The virus is a member of the Phlebovirus genus in the family Bunyaviridae. It was first identified in the Rift Valley in Kenya in 1930. The disease is a zoonosis but mainly affects domestic ruminants inducing massive abortions and a high mortality among young animals.

A substantial part of the Swedish outdoor education is being practiced in so called ?school forests?. The concept school forest was first introduced in the 1980?s by the organization Skogen i Skolan. The definition of a school forest is an area that is being used for educational purposes, over which the school and the land owner has reached an agreement of how the school may utilize it.

Today there is a research project undertaken by the Swedish University of Agricultural Sciences along with Wången (a highschool specialized in trotter training), which focuses on trotting horse training, performance and health. The project investigates how exercise intensity and feeding strategies affect the development of growing horses. The project includes two groups of horses where all 16 horses are fed in the same way. One group of eight individuals are trained 100% compared to conventional training and the other group are trained 20% less than the other group. All horses are trained twice a week and are out at pasture beyond that.

The purpose of this study is to give a picture of the current status for the recruitment to forest machine operator educations in Sweden, how many the educators are and the outcome of this activity. The three at present different types of education are upper secondary school, polytechnic school and vocational school. The method used for the survey is telephone interviews, pre-broadcast issues were discussed and the responses were recorded. The results are then compiled and presented in linear form. The conclusions one can draw is that education is desirable and important. To get young people interested in forest machine operator education it is very important that the forest industry continues to develop attractive employment..

Sweden's drinking water quality is considered to be high partly due to a high quality of the raw water and a well developed sewage infrastructure. Despite this, there is water contamination that could be prevented by installation of a sophisticated early warning system. Some of the major players in the production of drinking water have already invested in different types of early warning systems to ensure drinking water of high quality. There are various forms of early warning systems where automatic monitoring of E. Coli is an interesting alternative.

The milk production has developed rapidly the last years. The milk production per cow is increasing and the production units are larger with an increasing number of animals and a decreasing number of workers. Many milk producers invest in automatic milking systems (AM) to meet this change. In these systems the cows can voluntary decide milking frequency and usually the milking frequency are higher than two times per day. But how does the milking frequency effect the composition of the milk? The aim of the present study was to study the effect of milking frequency on the milk composition and the milk fat quality.

Purpose: The purpose of this thesis is to investigate to what a few preschool teachers and mother-tongue teachers consider the influence mother-tongue training has on children. The thesis also looks into how these teachers cooperate and view about the mother-tongue training organization structure and what support mother-tongue teachers get in the concerned preschools. More specifically:What influences do three preschool teachers and three mother-tongue teachers consider that mother-tongue training has on the development of the children?Which support do the three mother-tongue teachers receive from the preschool principals and other preschool pedagogues in their work? - Is there any cooperation between them?In what way do the three preschool teachers and the three mother-tongue teachers think that the mother-tongue training organization structure affect the children?s status in the group?Method: In order to achieve a deeper understanding of the context, a qualitative method based on interviews and observations was employed and relied upon. Three preschool teachers and three mother-tongue teachers from two different preschools in the same municipality were interviewed to acquire answers to the questions concerned.Result: The result of this enquiry shows a direct and explicit comprehension that mother-tongue is immensely important for children?s development.

This final thesis is a basic inquiry into a countryside programme for the municipality of Hässleholm. By interviewing people who live in the countryside in the municipality of Hässleholm I?ve tried to get a picture of how the thoughts on development of countryside are. Trough these interviews I?ve also tried to find out how people on the countryside defines the concept of countryside.

The purpose of this master´s thesis was to investigate the role and function of the annual reports of public libraries: for what purpose are they put together and how are they evaluated and utilised. The study presents different views on the structure and content of library annual reports. Focusing on a specific public library and its municipal administration, the authors identify and describe problems and possibilities regarding the library annual reports. The study also provides a general view of their occurrence, their addressees and the importance attached to them.In a review of current literature on accounting and activity reports the authors place the annual reports of public libraries in a wider context. The study also presents two current models of performance measurement - the Intangible Assets Monitor and the Balanced Scorecard - which were developed in the private sector, and the authors discuss their relevance when applied to public libraries.Data were collected both in interviews and by means of a questionnaire.