This literature study aims to examine the existence of cancer stem cells in breast cancer. The cancer stem cell theory states that there is a hierarchical organization within a tumour, in which a small subpopulation of the cells can initiate new tumours and maintain tumour growth whilst the bulk of the tumour cannot. These tumour initiating cells have shown to possess many characteristics similar to those of adult stem cells, which is why they are often referred to as cancer stem cells. Both cell types have the capacity of asymmetric division and have shown to possess mechanisms of resistance to both apoptosis and cancer drugs. The cancer stem cell theory elucidates many biological aspects such as the heterogeneity of tumours and the relapse of many cancers after what appeared to be successful treatments.

Aim: To investigate how three of the biggest political parties in Sweden made use of socialmedia in the election campaign in 2010, and to get a picture of how the parties perceive therole of social media in political communication today and in the future.Method: The research is conducted through personal interviews and qualitative textualanalysis.Theory: The theory that the study is based on is Habermas theory of the public sphereMain results: Social media is today an excellent channel for communication and informationbetween politicians and voters, and they will probably become increasingly important inpolitical communication in the future. So far, they are only an addition to the traditional mediaand are in no way substituted for them. Internet and some social media is an excellent forumfor political debate and opinion-former..

The purpose of this paper is to examine and analyze past development of mutual funds in large and small mutual fund companies and see if there are any differences between these two segments. Limitations on the number of funds have been made by choosing Nordic mutual fund companies that invest in emerging markets over an 11-year period. The study is made on 66 mutual funds managed by 13 mutual fund companies in which the segment of small fund companies includes seven fund companies with assets under management less than 100 billion SEK and the segment of large mutual fund companies includes six fund companies with assets under management more than 400 billion SEK. In the comparison of the segments the Sharpe ratio has been used to calculate the risk-adjusted return. The study shows small differences of the risk-adjusted return between the segments.

Following the wake of the AIDS-catastrophe in the beginning of the eighties, homosexual men or 'men who have sex with men' (MSM) have been barred from donating blood throughout the planet. In this thesis I look into the different discourses at play in the context of creating the legal framework for blood donation in Sweden. Genealogically tracing the emergence of the category of MSM and mapping how the category is brought to use in contemporary negotiations on blood safety, I scrutinize how scientific truth is established within blood transfusion practice. I argue that the rationality of risk group exclusion is contingent on economical grounds, and that the foucauldian concept of biopolitics could productively be used to understand this rationality. In particular, the concept of the 'biopolitics of blood' can be employed in order to understand the reluctance from the involved actors to acknowledge the heteronormative consequences of the legal framework of contemporary blood donation..

Parents today can be very stressed at the drop off and pick up of their children, this leads to that they sometimes miss important information that is pinned to the walls for example. Papers has the ability to disappear, a blog collects all in one place. Today, almost everything is digitized.This study has examined what a blog is and how schools and preschools can use it. The blog is used as a communication site for the preschools and school. This exam graduate work is made of three blog analysis, the analysis is made to see if the blogs can help the preschool and school to communicate wiht the parents.The theory I have decided to use in this study is the sociocultural theory.

This study examines the effects of credit risk and information disclosure in the new bank regulating system Basel II on bank and bank customer. The effects are then discussed in a perspective of the economic man and information asymmetric theories. Furthermore is the Basel II effects on the capital adequacy of Andelsbanken för Åland examined.The approach of the study is qualitative and several interviews with individuals on different levels of the examined bank, Andelsbanken för Åland, have been carried out during the collecting of empirical facts about the effects of the regulating change from the Basel I system to Basel II.The research findings are as follows:Andelsbanken för Åland have increased its capital adequacy ratio from 12,7 percent to 14,4 percent, mostly due to lower risk weights on housing mortgages compared to Basel I. Andelsbanken för Åland have started to use a completely new credit risk and customer assessment system which classifies every customer and gives them a credit rating. The system cause a much heavier information gathering of the customers profile as well as a much better assessment of risk than the previous system, which the bank finds positive.

Aim: The aim of this study is to understand why people have changed their preferred community over time. What are the main factors when changing to a new one?Method/material: The method has consisted of personal interviews with six different people in the ages between 20-22 and of different gender. The main material that has been used in this essay is the theory of Uses and Gratifications as explained by Denis McQuail, the theory of Convergence culture by Henry Jenkins and the theory about Communites of Practice by Etienne Wenger.Main results: This study shows a heavy affection that the use of communities often centers round the people around the community, rather than the functions that the communities themselves provides. Having people that you know on the community you choose is a vital part for people or at least having the support of other people and changing to another community at the same time.

Children are a group of patients that require special knowledge from the anesthesia staff, both general and specific. Theoretical knowledge and practical experience is necessary to adequately care for the child as it anatomically, physiologically and mentally may differ from adult patients.A growing problem in the pediatric population is overweight and obesity. From a stagnation in the early 2000s the prevalence of overweight and obesity among children in the world are again increasing.The purpose of this study was to examine peri-operative care of overweight and obese children.Systematic searches were done in PubMed, CINAHL and Scopus. After the quality audit according to SBU, twelve articles were included for analysis.Results suggest that overweight and obese children have a higher risk of respiratory peri-operative complications. The risk of hospital admission after outpatient surgery was also greater in this group as well as higher costs for health care.Overweight and obese children are complex subjects with more frequent peri-operative risk factors than normal-weight children.

Climate change and the sea level rise that it contributes to is an ever more pressing issue for costal municipalities around the world. Today there is a great deal of scientific reports and projections on what these changes could entail. However, resent studies on south Swedish costal municipalities have shown great discrepancies when it comes to how these scientific projections are implemented in the municipal planning and adaptation strategies. In an effort to understand the underlying reasons for this lack of concurrence, this paper has applied Rolf Lidskogs theory of the hetrogenity of science. The theory gives an explanation to the complications in the science-policy interface, by describing complicating factors in the communication between these actors.

Traditionally risk-based measures have been used to assess animal welfare in legislation and certification schemes. With increased knowledge and research, debate today tends to focus on and advocate the use of animal-based measures. However this is not a panacea for welfare and the most sound conclusion should be that assessment of animal welfare needs both. The aim of this thesis is to identify the points that need to be taken into consideration to find the optimal balance in the use of input and outcome measures according to the aim of the assessment and how these should be applied when designing a certification scheme? To answer this, a comparison of the use of resource-based, management-based and animal-based measures in two certification schemes for dairy cow welfare, Freedom Food (UK) and Svenskt Sigill (SWE), was made.

In Jan Jagers and Stefaan Walgrave theory about populism as a political communication-style they claim that one can find this in the rhetoric of political parties. In their study of Belgian politics they found that the extreme-right party Vlaams Block has embraced this populism to a larger extent than other parties. Based on this theory this thesis aims at finding populism as a communication-style in three different Swedish political parties with the purpose to see if the extreme-right party ?The Sweden Democrats? will show populism to a larger extent than other parties, as was the case in the Belgian study.Based on Jagers and Walgraves operational definition of populism as a political communication-style this thesis applies it to the rhetoric of three different parties being ?The Social Democratic Party?, ?The Moderate Party? and ?The Sweden Democrats?. This is done in order to be able to clarify on the one hand if their theory is applicable to the Swedish case and on the other hand to what extent populism as a communication-style exists in Swedish political rhetoric.The method for this thesis has been a qualitative text analysis since and leads to the result that Jagers and Walgraves theory of populism as a communication-style is applicable to the Swedish case and that ?The Sweden Democrats? to a larger extent uses this political communication style, than the two other parties..

AbstractTitle: The debut of gluten ? Does timing of gluten introduction affect the risk ofceliac disease in high-risk children?Author: Sandra Hagwall Frohm and Maria IngmarSupervisor: Frode SlindeExaminer: Mette AxelsenProgramme: Programme in dietetics, 180/240 ECTSType of paper: Bachelor?s thesis in clinical nutrition, 15 hpDate: May 26, 2015Background: Celiac disease is a chronic disease in which the intestinal mucosa is damaged bygluten exposure, and the only treatment is a lifelong gluten-free diet. The disease affects about1 % of the population worldwide, but the majority are undiagnosed. Ingestion of gluten and thegenotype HLA-DQ2/8 are required for disease development, although additional genetic andenvironmental factors are believed to be of importance. One hypothesis is that timing of glutenintroduction in infants affects the disease risk.

SAMMANDRAGHistorisk Simulation, Delta-Normal och RiskMetrics prestation utvärderas med hjälp av Kupiecs Backtest. Value at Risk (VaR) beräknas med tre olika konfidensnivåer utifrån Affärsvärldens Generalindex och HSBC kopparindex. Utifrån överträdelser från verkligt utfall undersöks vilken VaR-modell som estimerar marknadsrisken bäst. VaR-modellernas prestation jämförs, och i analysen utreds hur konfidensnivå och tillgångars egenskaper påverkar VaR-modellernas prestation. Resultaten visar att Historisk Simulation presterar bättre än Delta-Normal och RiskMetrics på den högsta konfidensnivån vilket troligtvis beror på att RiskMetrics och Delta-Normal antar normalfördelning.

Kovenanter ett amerikanskt fenomen som successivt har spridit sig över världen. I Sverige börjades olika typ av kovenanter användas under 1960-talet som kreditvillkor vid företagsfinansiering. Men även om kovenanter blivit ett vanligt verktyg inom den svenska kreditverksamheten sedan 1960-talet, finns det fortfarande bristande kunskaper om dess praktiska användande. Denna studies syfte är att utforska hur bankers användning av kovenanter i låneavtal påverkas av företagsspecifika, relationsspecifika, lånespecifika och andra faktorer. Studien är inriktad till att studera svenska bankernas användning av kovenanter vid företagskreditgivning och kommer därför inte att behandla privat och offentlig sektor.  Studiens ansats är abduktiv, som möjliggör en växling mellan teori och empiri.

Rättspsykiatriska patienter är en grupp med mycket psykosocial belastning i barndomen och mer forskning behövs kring bland annat huruvida det finns samband mellan denna psykosociala belastning, framtida brottslighet och bedömd risk för våld. Denna studies syfte var att jämföra brottslighet, psykosocial belastning i barndomen samt initiala riskbedömningar gjorda med HCR-20 på kvinnor respektive män vårdade vid Rättspsykiatriska Regionkliniken i Sundsvall. Vidare undersöktes ifall förekomst av psykosocial belastning i barndomen korrelerade med bedömd risk för våld bedömd med HCR-20 eller med brottslighet hos patienterna. Studiens sampel bestod av 10 kvinnor och 39 män varav majoriteten vårdades enligt LRV. Data samlades in från journaler, rättspsykiatriska undersökningar och domar samt genom enskilda intervjuer.