It generally takes 10 to 12 years for a new drug to hit the market. The pharmaceutical industry invests huge sums in these early stages of research and development. In spite of the rapidly rising research and development expenditures fewer and fewer blockbuster drugs are being developed. Longer lead times and aggressive generic post-patent competition have narrowed the timeframe for the pharmaceutical companies to profit on their investments.In the face of these threats the pharmaceutical industry has developed a battery of strategies to prolong market exclusivity and to maximize return on investment. These emerging strategies are commonly known as Life cycle management (LCM), which actually is more of a concept than a method.

Denna studie är utförd inom lärarutbildningen och kursen Språk och språkutveckling. Syftet med arbetet har varit att undersöka hur elever i år 1 agerar under boksamtal och vilket lärande som gestaltas i dessa samtal. Sex elever i år 1 har deltagit i en serie boksamtal som planerats och genomförts med inspiration av den sokratiska samtalsmodellen (Lindström, 2000). Studiens resultat har belysts med tre teoretiska perspektiv; ett didaktiskt perspektiv, ett receptionsteoretiskt perspektiv samt ett läsförståelseteoretiskt perspektiv. Tre kategorier av läsförståelsestrategier identifierades; att fråga, att göra inferenser och att läsa.

The point of the study is to investigate educational and vocational counselors' strategies on drop in calls. In order to answer the purpose, the issues concerning the educational and vocational counselors' strategies and guidance models/methods at drop-in calls investigated.Qualitative interviews were conducted with six educational and vocational counselors'.In the study it appears that the educational and vocational counselors' are unable to have any strategies for drop-in conversation because the applicant will come spontaneously and the educational and vocational counselors' lack information about the individual and its purpose of the interview. Guidance models/methods designed to facilitate for the applicant and give them a sense of understanding about them selves there environment and results in a clarification of the election, not often used during the drop-in calls.These are not often used due to the lack of time because the intention of the call is to provide with information to the applicant in as little time as possible. In an educational and vocational counselors? perspective the guidance that is offered at drop-in calls defective..

The WT1 gene is a complex gene originally known to suppress cancer in kidneys. Studies of WT1 knockout mice have confirmed the important role of WT1 in the pathogenesis of Wilms? tumour, a tumour which counts for 95% of all childhood renal tumours. In that case the WT1 gene acts as a tumour suppressor gene. Subsequent research has shown that the WT1 gene in many other cases acts as an oncogene, e g in leukemia or lung cancer (even though these cancer forms can emerge as a result of many other aetiological factors).

In Kenya the Maasai pastoralists have based their livelihoods on dairy production and the production goal is to maintain a sufficient milk supply throughout the year. The pastoral dairy production has two vital characteristics; breeding and milking. Traditionally, breeding is the men?s responsibility, while milking is the duty of women. Depending on this partition of chores between men and women, they also have different management routines, ambitions and strategies regarding the milk production.

Modern semiconductor design methods makes it possible to design increasingly complex system-on-a-chips (SOCs). Testing such SOCs becomes highly expensive due to the rapidly increasing test data volumes with longer test times as a result. Several approaches exist to compress the test stimuli and where hardware is added for decompression. This master?s thesis presents a test data compression method based on a modified facsimile code.

In this study I investigated whether the strength in the manual response for emotional and neutral stimulus search arrays can explain some of the difference in reaction times (RT:s) for emotional stimuli, or not. Earlier, perceptual, cognitive and attentional processes has mostly been used to explain the variance in RT:s. Thirtythree individuals were asked to, as fast as possible, detect a target picture among distractor pictures in 3 rows x 4 columns arranged search arrays. The pictures were categorized in fear relevant animals (snake, spider) and neutral animals (cat). The results showed, more correct responses for cat target.

During the last two years Gothenburg has become a central point in Sweden foractivists in the area of disability. The essay explores which strategies that activist usesin purpose to pay attention to and criticize the Normate. By doing so, five cripactivists have been interviewed about their experiences and feelings about how theymanage to stand up against different types of power relations. The activists describehow they develop different strategies to change their identity positions and takecontrol over themselves.The essay intends to contribute with a crip theoretic view in combination withmaterial feminisms and resistance theory. The conclusions of the essay shows that thenormate is incorporated in both social and material matter and how the activist?s usesthe strategy Critical Disability to negotiate their identity position.

This thesis examines the USA?s response to the military coup in Myanmar 2021 through a comparative analysis of the two dominant international relations theories: realism and liberalism. The study uses a qualitative text analysis of the US Burma act of 2021 to test the explanatory power of the theories in the formulation of US policy. The results shows that liberal theory has the greater explanatory power, as the US response was systematically motivated by a normative desire to restore democracy in Myanmar. However, some realist tendencies could be observed, especially through exception clauses preserving US national security interest and the mention of China?s support for the military junta in Myanmar.

This thesis aims to explore the process where strategies for music artists are created by record companies. We describe and analyze how decisions regarding signing, distribution, marketing, bookings and co-operations are made. Through our study we find that the strategy process can be described as a pattern according to Mintzberg's definition. The "inside-out" perspective is dominating and the record companies base their strategies on internal core competencies and the artistry and will of the music artist. The underlying causes of this are the uncertainty that characterizes the industry; the focus on social relations; and the importance of cultural legitimacy..

The study has shown that retailers in the mid-price segment differentiate their brand through developing a strong company identity around the brand. The personality involves store atmosphere, merchandise and advertising. Larger companies have chosen to lay the responsibility on management level, which facilitates on store level. By controlling the strategies on a central level the company can make sure that the stores are steered in the direction that the company wants them to be steered in, and also that they follow the positioning-concept. The company can also devote its efforts to working with its core value, which is service.

Dementia may cause difficulties in communicating. People suffering from dementia are therefore often described as being unable to take part in meaningful conversation. The responsibility to create understanding in a conversation is shared by all participants. By means of different strategies, participants in conversation can construct understanding through collaboration. How these strategies are utilized in conversation where one or more of the participants suffer from dementia is relatively unknown.

In this paper I have conducted an analysis to critically examine survey questionnaire forms used in political research to measure trust and distrust. During the first step of the analysis I aimed to identify how the concepts where used in the forms. The second step involved examining if it was possible to relate the questions and items to five theoretical assumptions based on theories of trust (and distrust). The third step was to examine the quality of the forms, in relation to survey and questionnaire designs.The results of the analysis showed that the institutes that conduct the studies tended to use similar questions to measure trust. Some of the forms that where analyzed had very many questions, which could lead to exhaustion for those participating in studies.

The aim of this paper is to investigate the subject matter of visual communication in presentation brochures of two Swedish regions: Region Halland and Region Dalarna. My focuses are the following questions: what is the aim of the brochures and in what ways does the visual material relate to that aim? How can strategic communication be defined through a visual perspective and in what ways is it useful in the context of presentation brochures of the regions? What sort of communicational functions are specific for the visual material in relation to the written language of the brochures? Lead by these questions, I start by analyzing the brochures through a textual analysis and a social semiotic approach. The result shows that the aim seems to be both political and commercial, but that the visual elements relate more strongly to the commercial aim than to the political aim by the way they strive to present a positive image of the region. The visual elements work in strategic ways that I define as visual strategies.

The purpose of this study was to examine work related stressors and related coping strategies among case managers at a domestic violence shelter in the United States. We further wanted to examine whether locus of control among the participants could be related to work related stress and coping strategies. Qualitative interviews were performed with eight case managers to gain knowledge about the stressors and coping strategies they used by examining their thoughts, feelings and experiences. The result showed that the case managers experience a number of stressors in their work environment such as system problems (e.g., lack of re¬sources and time pressure) and emotional stress. Coping responses among the case managers included efforts to alter the problem, so called problem focused coping, efforts to control emo¬tions, so called emotions focused coping and social support from colleagues.