Abstract Tripeptidyl-peptidase II (TPPII), is present in most eukaryotic cells. It cuts tripeptides from the N-terminus of peptides and is especially important for degrading peptides longer than 15 amino acids. TPPII also tailors long peptides into suitable substrates for the enzymes which transport and produce the peptides that MHC I present. Increased levels of TPPII have also been found in certain cancer cells, thus it is of interest to determine if TPPII could be used as a tumour marker.The aim of this study was to optimise and evaluate 3 different methods for quantifying TPPII. Western blot, enzyme-linked immunosorbent assay (ELISA) and fluorophore-linked immunosorbent assay (FLISA) protocols were optimised regarding incubation times and antibody dilutions.

The purpose of this paper is to investigate the possibility of replacing data from highspeed filming (Qualisys motion capture) with data from Inertial Measurement Units (X-io technologies), when used to run a model of torso and pelvis in OpenSim. Qualisys motion capture data is used as the golden standard to validate the result visually and with Bland-Altman plots.In order to obtain comparable data experiments are conducted where both methods of collecting data are used simultaneously. Data from the IMU's then need to be processed in Matlab before it can be used to run the OpenSim modell. Several Matlab programs rotate the IMU data to a static reference frame, filter and integrate it, then create viritual markers that correspond to Qualisys' optical markers.The conclusion is that using IMU as a method for collecting data can replace Qualisys in some applications, but not in ones that require high precision. However, this paper only begins the examination of IMU's and there are most likely improvements to be made..

A common assumption in marketing is the wider variety of product a corporation has, the better for the consumer: more product - more choices. Companies often develop a line extension to broaden consumer range through product attributes including quality, function and design. These developed attributes within the product are not always optimal for the consumer. As a result, companies often become entangled in having a price higher than the cost and benefit of the products. This essay aims to analyze the consumer value of line extension products and how these evaluations relate to extended line product pricing.

The aim of this piece of work is to highlight and investigate young female?s motivation in participation of P.E classes and the degree to which the content of classes affect their motivation. To support this piece of work two theories have been utilized, the Self-determination Theory and a gender related perspective theory. The research consists of six qualitative interviews of young females who are perceived to be less motivated. These interviews focus on their views and attitudes in relation to P.E within the Swedish high school setting.

Syftet med denna studie är att utreda begreppen big data och analytics. Utifrån vetenskapliga teorier om begreppen undersöks hur konsultföretag uppfattar och använder sig av big data och analytics. För att skapa en nyanserad bild har även en organisation inom vården undersökts för att få kunskap om hur de kan dra nytta av big data och analytics. Ett antal viktiga svårigheter och framgångsfaktorer kopplade till båda begreppen presenteras. De svårigheterna kopplas sedan ihop med en framgångsfaktor som anses kunna bidra till att lösa det problemet.

Three-dimensional computer graphics enjoys a wide range of applications of which games and movies are only few examples. By incorporating three-dimensional computer graphics in to a simulator the simulator is able to provide the operator with visual feedback during a simulation. Simulators come in many different flavors where flight and radar simulators are two types in which three-dimensional rendering of large terrains constitutes a central component.Ericsson Microwave Systems (EMW) in Skövde is searching for an algorithm that (a) can handle terrain data that is larger than physical memory and (b) has an adjustable error metric that can be used to reduce terrain detail level if an increase in load on other critical parts of the system is observed. The aim of this paper is to identify and evaluate existing algorithms for terrain rendering in order to find those that meet EMW: s requirements. The objectives are to (i) perform a literature survey over existing algorithms, (ii) implement these algorithms and (iii) develop a test environment in which these algorithms can be evaluated form a performance perspective.The literature survey revealed that the algorithm developed by Lindstrom and Pascucci (2001) is the only algorithm of those examined that succeeded to fulfill the requirements without modifications or extra software.

Title: Sibling experiences ? to grow up with a sibling with Asperger syndromAuthors: Anna-Lena Hedlund and Monica OlofssonKey words: Asperger, siblings, relations, supportTo grow up with a sibling diagnosed with Asperger syndrome may differ from what is considered as normal. It can be challenging, but also instructive in some ways. This study examines how it is experienced by the siblings with no diagnosis. The aim is also to investigate how many of them who acquired some kind of support or, if not, would have wished that.Qualitative data are collected by means of five interviews with non-diagnosed siblings.

AbstractNowadays, companies and organizations manage large amounts of data to be used as support in decision making. A good solution for data management is in the form of data warehouses. A data warehouse is used to gather information from multiple sources within a company and arrange the information in a way that makes it easy to retrieve and analyze. Designing a data warehouse is not a simple task. The study herein will focus on what a data warehouse is and how the ETL process is used for data storage in the data warehouse. ETL stands for Extract, Transform and Load and is the process that retrieves data, transforms it and finally loads it into the data warehouse.

This literature review summarizes available data on infection with the parasitic roundworm, Ascaridia galli, as a cause of disease in poultry, including the consequences of a conversion to alternative production systems. Ascaridia galli has a direct life cycle with resistant eggs that survive and are easily spread in the environment, especially in systems with bedding materials where the faecal contact is high. The infection is usually subclinical but depending on the infection dose, the symptoms range from weight loss and diarrhea to mortality. Factors such as the feed composition and genetic variation among different hybrids clearly affect the establishment rate of the infection. Ascaridia galli will probably become an increasing problem, with a shift from the traditional battery cages to alternative systems where the risk of re-infection is high.

The absence of female directors on Swedish corporate boards is currently a hot topic for both politicians and business leaders all over the world. This thesis aims to discuss reasons for the scarcity of women on boards in Swedish publicly listed companies as well as what actions are taken to alter the composition of these boards. A rigorous selection of gender theories have been used together with data collected from in-depth interviews with mainly board members and nomination committees. Extensive analysis has led to findings that historical perceptions of differences between men and women linger as of today, which prevents women to reach top executive levels as well as board positions. The increasing use of headhunters has encouraged companies to look beyond male-dominated networks in an attempt to widen the range of potential board nominees.

From an environmental and climate perspective we are becoming more and more aware of what we eat. Consumers want to know how their food is produced and where it is coming from. A term commonly used in this discussion is local produce. At this time, there is no clear definition of the term and a wide range of definitions can be found. However, despite this lack of definition, the term is often being used by producers, traders and consumers..

This paper researches how the palimpsest concept is used in relation to landscape, and how it can function as a tool within landscape architecture. Palimpsest originally refers to old parchment handwritings, where new text has been applied on top of effaced, but still discernable, earlier writing. Superimposition of information is the core of the palimpsest concept, used within a range of scientific as well as cultural fields. The purpose of this paper is to find how a landscape palimpsest can be distinguished among the many different layers of landscape, such as historical or cultural, and to examine the potential use of the concept in theory and practice of the landscape architecture field. The study is conducted as a literature survey, examining the use of the palimpsest concept within academic works related to landscape.

The main purpose of a Flight Data Recorder (FDR) is to facilitate the investigation of incidents. In order to interpret the data that has been recorded in the FDR the data has to be visualized in some way. This can be done with software on a computer or with hardware that is specific for the model of aircraft that the data originates from.The aim of this project is to visualize data for six parameters from the FDR of Saab 2000 in an avionics rig. The avionics rig resembles the cockpit of Saab 2000 and the displays in it are identical to the ones found in the plane. All six parameters are shown on the same display.Due to safety regulation vital systems in aircraft are doubled, with one system on the left side and one on the right.

The calcium homeostasis in the body is normally strict regulated to be kept within very narrow limits. This regulation is due to the action of parathyroid hormone (PTH) which is synthesized in the chief cells of the parathyroid glands. In different diseases, the calcium homeostasis is disturbed and this could either be due to a dysfunction of the parathyroid gland itself, or it could have a completely different explanation. To investigate disturbed calciumhomeostasis, ionized calcium and PTH can be analyzed from a blood sample. There are a lot of different assays to measure PTH in humans.

The purpose of this master?s thesis is to examine how librarians perceive the importance of staff reading groups in helping to make fiction more accessible to adult users of public libraries. The study also examines how librarians perceive the learning processes in such groups, and what these learning processes involve and how they appear. The empirical data was acquired via observations of four staff reading groups and interviews with seven public librarians who took part in the groups. In part, the empirical data is interpreted by means of Lena Wilhelmsson?s analytical tool, which deals with changes of perspective within an organised group.