The aim of this master thesis was to examine a possible connection between chromatin functions and the DNA damage repair system, with the imprinted IGF2/H19 locus as a bait. Interactions can occur within and between chromosomes and it has been shown that H19 ICR on both alleles can communicate with alleles on other chromosomes. The methylation-sensitive insulator protein CTCF is bound on the maternal H19 ICR and acts as an insulator by blocking the IGF2 promoter to access its enhancers. This is possible by formation of loop structures by CTCF that enables intra and inter-chromosomal interactions. CTCF is poly(ADP-ribosyl)ated by PARP-1 when it is bound to H19 ICR.

An increased demand for processed goods on the property market has contributed toinvestments within the Swedish sawmill industry. The purpose with this study is to make amarket investigation of pre cut lengths within a defined geographic area. The constituent forthis investigation is HAL (AB Hilmer Andersson) who invests in a new plane facility and twofinger jointing machines in affiliation to their sawmill in Lässerud, the vest part of Värmland.To investigate the demand of pre cut lengths and identifies the value creating factors and costfactors which the customer within the segments industry and property market perceive, havedifferent customer value theories been used. Theories of customer value and the theory aboutoffering has been the source of creating the qualitative interview with a selection of currentand new potential customers for HAL.The result of the study first gives an introduction of HAL?s new offering and a description ofHAL?s current customers, which gives the reader an understanding of why searching for newcustomers is made in the defined area.

Denna uppsats behandlar svenska börsnoterade fastighetsbolags tillvägagångssätt att värdera sitt fastighetsbestånd. Både när det kommer till metod och typ av värdering (graden av intern kontra extern).Vidare undersöks faktorer som står till grund för dessa och hur företagens värdering har förändrats sen en kortare tid tillbaka.Uppsatsen kombinerar analyser av finansiella årsredovisningar från svenska börsnoterade fastighetsbolag med ett par kvalitativa intervjuer med några av de högst respekterade och uppsatta personerna i fastighetsvärlden.Analyserna visar på att en majoritet av fastighetsbolagen använder en hög grad extern värdering tillsammans med avkastningsbaserade värderingsmetoder. Även en förändring av fördelningen mellan intern och extern värdering under de senaste fyra åren konstateras och reflekteras över.I intervjuerna jämförs bland annat interna och externa värderingars riktighet och trovärderighet ur två väldigt olika perspektiv. Här tas även problematik upp och skillnader i teori och praktik..

The purpose of this essay is to examine whether the descriptions of Stalin's terror in history textbooks for high school changed from the 1950s until the 2010s. Since previous research shows that textbook content is influenced from different directions and that it dominates in teaching, therefore I want to find out what similarities and differences that exist in the textbooks. The survey is based on a qualitative approach because I want to have a profound picture of the descriptions of Stalin's terror. The results of the survey show that the number of casualties and the descriptions on the famine has changed over time. Furthermore, textbooks also found it difficult to distinguish between terror, politics and ideology.

E-Series 450 is a chainsaw designed by Husqvarna AB to the semi-professional user. Husqvarna is a world leader when it comes to chainsaws, trimmers, lawn mowers and garden tractors. The problem in hand can be addressed by the question. ?How easy can we start a chainsaw? The purposehas been to provide a solution to the question above and give Husqvarna a good base of which they can continue towards a finished product.

The effects of social media usage in a professional context, specifically the effects on social media usage in relation to leadership have been studied in order to determine weather or not usage can be productive for leadership in general. The study concludes that there are several benefits as well as drawbacks to leadership in using social media, but has yet to conclude weather productive or not. This study gives an overview of a relatively unexplored subject.Leadership in terms of leader, communication and group dynamics have been defined and explained in accordance with existing literature. A  brief review of computer and Internet history attempts to explain the formation and evolution of social media. Risks in terms of risks related to leadership and risks related to IT-security are taken into consideration and have been briefly explained.

The effects of social media usage in a professional context, specifically the effects on social media usage in relation to leadership have been studied in order to determine weather or not usage can be productive for leadership in general. The study concludes that there are several benefits as well as drawbacks to leadership in using social media, but has yet to conclude weather productive or not. This study gives an overview of a relatively unexplored subject.Leadership in terms of leader, communication and group dynamics have been defined and explained in accordance with existing literature. A  brief review of computer and Internet history attempts to explain the formation and evolution of social media. Risks in terms of risks related to leadership and risks related to IT-security are taken into consideration and have been briefly explained.

Att sluta eller inte sluta? En litteraturstudie om tobaksavvänjningsmetoder Bjellman, K. Tobaksbruket har en lång historia, och de tobaksrelaterade sjukdomarna kostar samhället miljarder i sjukvårdskostnader och produktionsbortfall varje år. Andelen rökare minskar stadigt i Sverige, idag röker ca 15 procent av befolkningen. Resultaten från olika metoder för tobaksavvänjning är tämligen blygsamma, och ugefär nittio procent av de som slutar röka gör det på egen hand.

E-Series 450 is a chainsaw designed by Husqvarna AB to the semi-professional user. Husqvarna is a world leader when it comes to chainsaws, trimmers, lawn mowers and garden tractors. The problem in hand can be addressed by the question. ?How easy can we start a chainsaw? The purposehas been to provide a solution to the question above and give Husqvarna a good base of which they can continue towards a finished product.

AbstractThe purpose of this essay is to investigate how a local authority acts when anunexpected event occur. It´s done with a basis in two crisis communicationstheories; Coombs SCCT theory and Gilpin and Murphys complexity theory,which largely are each other?s opposites. To conduct the study, a case studyof the floods that hit Kristinehamn in the summer of 2014 was carried out,which gave us a good opportunity the achieve the aim of the study. Themethod used was qualitative research interviews.

Development and construction of an electronic Breakout box is the main work for this thesis. The box is a part of a test system for the component Fuel Flow Transmitter and should convert signals to be suitable for a frequency counter. A previously constructed Breakoutbox for this purpose is being old and needed to be recreated. So SAAB Aerotech, Aircraft services, the company for the thesis work wanted to construct a new, more sustainable Breakoutbox adapted to a more modern technology. The signals to the box comes from the transmitter and should be converted to suitable signals for a frequency counter so it can show pulse and time difference between the signals.

Real estate managers work in a hard branch with big competition and skeptical customers. For most people, buying a property is the biggest private purchase of their lives. This puts a big pressure on the real estate agent to make the process run smooth. But how does the customer know which real estate manager to choose? We have researched what effect the real estate managers clothing has on the customers? first impression and how clothing affects customers? choice of real estate agents.To answer our questions we´ve done 13 projective interviews with ten customers and three real estate agents, where we showed four pictures with the same person dressed in different styles.

The written sources concerning the process of christianization in Sweden has for a long time been limited to two main texts, Rimberts vita of St. Ansgarius and Adam of Bremen´s History of the bishops of Hamburg. This is due to a rigid source criticism in the beginning of the 20th century, which put other material ? in particular the norse sagas ? out of consideration. The last twenty years however, new questions have been raised concerning the christianization, partly because of new archaeological findings, new interpretations of the significance of runic stones and the recent debate about the formation of the Swedish medieval kingdom.

A hearing loss may affect the identity development and participation among adolescents. To understand adolescents with hearing loss in modern society, it?s of great importance to ascertain how identity- and participation processes occur in new areas, such as the internet.Objective: The aim of this study was to investigate what research shown regarding identity development among adolescents with hearing loss and whether social processes on the internet may influence the participation of this group.Method: A literature review was conducted to obtain a cohesive framework of research about participation processes and identity development among adolescents. Included articles have been published 1995-2015.Results: The results show the importance of the individual?s identification with the surrounding.

Jag har i mitt projekt jobbat med mönsterformgivning och produktion av vävda möbeltyger, digitaltryckta tapeter- och textilier för en fiktiv hemmiljö. Mina designbeslut grundar sig på en fiktiv karaktär, Mr Chester Jester, hans estetiska preferenser och behov i samrådan med mina egna. Arbetets resultat är en gestaltning av världen han lever i, komprimerad till ett hemma hos reportage på gränsen mellan verklighet och illusion. Jag har jobbat med dubbelhet och speglingar - av mönster, av rummet, av tekniker och mig själv. Jag har undersökt illusionens verklighet och verklighetens illusion.My bachelor project is a work of pattern design and production of woven upholstery fabrics, digital prints on textile materials and wallpaper, made for a fictional home environment.