Sahlgrenska Academy at University of Gothenburg Department of Internal Medicine and Clinical NutritionAbstractTitle: Can Probiotics prevent atopic dermatitis in children with high risk?Author: Laura Pienihäkkinen and Max OlinSupervisor: Heléne Bertéus ForslundExaminer: Anna WinkvistProgramme: Dietician study programme, 180/240 ECTSType of paper: Examination paper, 15 hpDate: May 22, 2012Background Allergic disease is today common, this including atopic dermatitis, which is the most common inflammatory skin disease in the world. Heredity has been shown to play a major role in the development of this disease. It is therefore of high interest for both the individual and society to find effective methods for preventing atopic dermatitis in individuals with high risk profile. Probiotics are beneficial for the bacterial profile in the intestine and it is therefore of interest to study if they through their anti-inflammatory effect could prevent atopic dermatitis.Objective The aim was to study whether administration of Probiotics to the mother and the child (directly or via breast milk) could prevent atopic dermatitis in children with high risk profile (at least one first degree relative with a diagnosed allergic disease).Search strategy A systematic literature search was done in databases PubMed and Scopus with search terms maternal, prenatal, Probiotics, allergy, atopic dermatitis, prevention, and children.Selection criteria Randomized, controlled human studies and original articles in English were included.

About 10 % of the adult women population in Sweden are treated annually for urinary tract infections. The increasing bacterial resistance towards antibiotics is classified by WHO (World Health Organization) and ECDC (European Centre for Disease Prevention and Control) as one of the greatest treats for human health in a global perspective. To find alternatives scientists are studying the possibility to use Probiotics to reduce the frequency of recurring urinary tract infections. This literature study examines five randomized double blinded placebo controlled studies where different strains of Lactobacillus have been used as a prophylactic to women suffering from recurrent urinary tract infections and bacterial vaginosis. Overall the studies do not display enough promising results to recommend the use of Probiotics as a prophylax or cure..

Iron deficiency is one of the most frequent micronutrient deficiencies around the world. Low iron bioavailability simultaneously with a high iron requirement is a high risk factor for developing iron deficiency. Probiotics are microorganisms that confer a health benefit on the host. Prebiotics are oligosaccharides which provide a health benefit on the host due to a positive modulation of the microflora in the gut. The aim of this paper is to evaluate if there is a connection between pro-and/or prebiotics and iron bioavailability.

Abstract Cavities used to be a very common problem but over time humans have learned to take care of their teeth. However, there are still many who have problems. This problem is due to microorganisms and in particular the various streptococci and lactobacilli producing acids which loosens up the enamel on teeth. These bacteria can be found at various places in the mouth and saliva. Besides being a discomfort it can be a major problems and the damaged tooth needs to be removed or make a dental filling. The aim of the study was to see how intake of probiotic tablets containing Lactobacillus reuteri PTA ATCC 5289 and Lactobacillus reuteri DSM 17938 affects the levels of oral Streptococcus mutans and lactobacilli over a three-week period.

Bakgrund och syfte: Intresset för enteral administrering av probiotika i förebyggandet av infektioner och diarré har på senare tid ökat. Nosokomiala infektioner och diarré är ett stort problem hos intensivvårdpatienter.  Syftet med denna studie var att undersöka hur enteral probiotika påverkar sjukdomsförloppet hos intensivvårdspatienter, med avseende på mortalitet, infektioner totalt, ventilatorassocierad pneumoni (VAP) och diarré.Metod: En systematisk litteraturstudie med sökning i Pubmed och Cinahl genomfördes med följande Meshtermer; Probiotics, lactobacillus, critical illness och intensive care unit. Därefter genomfördes en metaanalys av randomiserade kontrollerade studier, utförda på vuxna intensivvårdspatienter, där man jämfört patienter som erhållit probiotika med patienter som fått placebo eller annan behandling.Resultat: Totalt 15 studier med sammanlagt 1293 patienter inkluderades. Ingen signifikans med avseenden på mortalitet, infektioner totalt, VAP och diarré kunde utläsas i metaanalysen.

Since the first wolf was taken as a companion animal a lot have happened with the biology of these animals. Is it possible that changes in the gut microbiota of the domestic dog are involved in the increasing numbers of animals with gastrointestinal disorders? Probiotics have been proven to promote the immune system of dogs by increasing concentrations of neutrophils and monocytes, decreasing the fragility of erythrocytes and increasing the serum IgG concentrations. Probiotics have also been shown to improve the fecal consistency, fecal dry matter and defecation frequency of dogs. The aim of this study was to find out if the bacterial counts in the gut of dogs differed from the gut of wolves, with the focus on lactobacilli.

Bakgrund: I Sverige drabbas vuxna av i genomsnitt en till två förkylningar per år och barnminst dubbelt så ofta. Totalt betalade Försäkringskassan ut 4 656 667 vab-dagar (vård avbarn) under år 2010. Probiotiska bakterier i tarmen konkurrerar med sjukdomsframkallandeorganismer och reducerar dess förekomst i tarmfloran. Om probiotika kan användas för attminska eller åtminstone förkorta sjukdomstiden skulle det vara en enkel metod till en relativtlåg kostnad vilket sparar tid, pengar och lidande för alla parter.Syfte: Syftet med denna systematiska översiktsartikel var att undersöka huruvida ett dagligtintag av probiotika skulle kunna skydda mot eller lindra förkylning, feber ochinfluensasymtom.Sökväg: Litteratursökning i databaserna PubMed och Scopus har genomförts. Sökord somanvändes i olika kombinationer var: Probiotics, effect, common cold, fever, flu, influenza,respiratory diseases, lactobacillus och bifidus.Urvalskriterier: Inklusionskriterier vid litteratursökningen var humanstudier i RCT-form därinterventionen varit dagligt bruk av probiotika.

Lactobacillus reuteri has been used as Probiotics in piglet and chicken feedings as well as in different diary products for humans. In this EEF-work I have shown that L. reuteri can be an alternative for treatment of vaginitis in laboratory rats used for breeding. In a breeding stock with 3000 animals some animals had a vaginal infection with ??haemolytic streptococci group G.

Obesity is a problem that increases exponentially in humans and companion animals. It is defined as a big accumulation of fat in the body and is usually connected with several diseases. This study describes how obesity can be diagnosed, in which way the gut flora can affect obesity, if the gut flora is genetically influenced or not, and how it differs between individuals with obesity and obesity-related diseases. Conclusions of the study are that both the bacterial strains Bacteriodetes and Firmicutes probably have a connection to obesity. The intestinal flora is probably also genetically related.

Probiotika, nyttiga bakterier som är välgörande för människan, förekommer allt mer i olika produkter riktade till små barn ? alltifrån droppar och kapslar till modersmjölksersättningar och grötar. Inom barnhälsovården saknar barnsjuksköterskan/ distriktssköterskan vägledning och riktlinjer angående probiotika i små barns kost. Syftet med litteraturstudien var att undersöka evidens angående probiotikas hälsoeffekter i preventivt syfte på friska små barn. Metoden var en litteraturstudie baserad på 20 vetenskapliga artiklar.

Bakgrund: Ett lämpligt näringsintag är viktigt för främjandet och bevarandet av både den allmänna och orala hälsan. Karies är en multifaktoriell sjukdom där kosten har en betydelsefull roll. Kosten kan bidra till både kariesförekomst och kariesprevention. Functional food definieras som ?livsmedel som ger hälsovinster utöver basnutritionen? och ?livsmedel som har en eller flera tillsatser som modifierats för att bidra till en hälsosam kosthållning?.

Probiotics is a special group of health products on the market. The most common type of  these is live cultures of lactic acid fermenting bacteria from raw milk . These include, among others, yogurt and various trademarks such as Hälsofil ®, Acidophilus ®, Dofilus ® and Kefir ®. Such products are often used by patients who are treated with antibiotics to combat the intestinal flora eliminated, thus causing digestive problems. The present work deals with yet another type of health product, viz.