The process of drug discovery is very slow and expensive. There is a need for reliable in silico methods; however the performance of these methods differs.This work presents a targeted study on how the drug discovery methods used in OpenEye?s tools ROCS, EON and FRED perform on targets with small ligands. It was examined if 12 compounds (markers) somewhat similar to AMP could be detected by ROCS in a random data set comprised of 1000 compounds. It was also examined if EON could find any electrostatic similarities between the queries and the markers.

The purpose of this master thesis is to evaluate how the current share price and market consensus affect security analysts target price and if an investor should pay any attention to it. Empirical data is primarily collected from qualitative interviews with ten security analysts but also from a quantitative e-mail survey. Our main finding is that security analysts are indeed affected by each others earnings forecasts as well as the current share price. This is not strange, it is in several aspects rational. Security analysts has often nothing to gain by standing out too much and not either by spending too much time trying to create their own opinions due to lack of time or the complexity of what is analyzed.

ABSTRACT TITLE: Oil price shocks impact on the British and the Swedish stock markets SEMINAR DATE: 2007-06-07 COURSE: Bachelor thesis in Business Administration and Economics, 10 Swedish credits (15 ECTS) AUTHORS: Carl Hersaeus, Sven Piehl Trygg ADVISORS: Hossein Asgharian, Göran Andersson KEY WORDS: Dummy Variables, United Kingdom, Oil Price, OLS, Regressions, Stock Markets, and Sweden PURPOSE: The purpose of this paper is to study whether, and how, oil price shocks have an impact on British and Swedish stock markets. METHODOLOGY: Our paper is based on secondary data, focused on historical spot prices on Brent oil and stock indices from Sweden and UK. We construct dummy variables to register positive and negative disturbances in the oil price. Furthermore we try to find a relation between the price disturbances and the different stock indices. THEORY: We take off from earlier studies, which prove that there is a relation between oil prices and stock markets.

The purpose of this report is to compile and examine the cost of renovation of moisture-damaged bathrooms, to derive a target price. The target price can then be used by insurance companies to estimate the ultimate cost of future bathroom renovations.       The method is based on the compilation and comparison of the cost of repairs of previous water damage in bathrooms. The calculations compiled based on repair estimates for different insurance losses from one of the leading insurance companies in Sweden.       The result shows the average price per square meter of floor area for different sizes of bathrooms. The average price is the basis for the estimate of future renovation costs of bathrooms. The results further show that the bathroom finishes, area and the distance between the entrepreneur and the location of the renovation have great impact on the final repairing cost.

This report will try to evaluate the use of rented concrete casting moulds, which are used to build walls and system of joists. The evaluation is only examining the economical aspects.The cost of using concrete casting moulds is a big part of the total production expenses. Therefore it is important that the calculated price not exceeds the final costs of the casting moulds. The calculated price is the price used in the process of making an offer.The evaluation consists of a comparison of the calculated price and the final costs for three building projects. It also evaluates the exploitation of the concrete casting moulds for each project.The report is made by Sven Gynne and Anders Alexandersson at School of Engineering, Jonkoping University, in cooperation with PEAB Jonkoping.

AimThe purpose of this study is to analyze factors that affect the price on tenant-owner apartments in the central parts of Uppsala. Special attention is put on analyzing how the monthly fee and the location affect the price. The hypotheses are that the monthly fee and the distance to the central part of the city have a negative effect on the price. A number of additional price affecting factors was taken in consideration during this study.MethodThis study is mainly based on data supplied to us by Mäklarstatistik. The supplied data consists of information about tenant-owner apartment sales in Uppsala during a year under 2008 and 2009.

During the past 20 years, the price of forest estates in Sweden has raised more than the price of timber. The purpose of this study is to investigate if it, despite this development, is possible to buy a forest estate based on economic grounds. Different forest parameters will also be studied to analyse their effect on the profitability. The study is done in cooperation with the company LRF Konsult. Purchase price of 34 forest estates near the coast of Norrbotten, Sweden, has been compared to yield valuation. For the valuation, guidelines from the Swedish author Lantmäteriet was used.

This is a thesis project in the field of information technology which begins by evaluating existing food price comparison systems and subsequently aims to design an improved, web based system for said purpose. The system features interfaces for price reporting, price comparisons as well as various search and review functions. The objective is to create a system able to compete with existing price comparison systems, which requires careful selection of products that can be found in all foodstores that also represent different households; a user-friendly price reporting and price comparison interface and an efficient tool for ensuring the validity of reported prices.The designed system features a more accurate formula for calculating average prices in events where the real price is missing; a more reliable security mechanism forv alidation of reported prices and a more comprehensible interface for viewing price reports, reporting prices, reviewing stores and products in comparison with existing systems. The system does, however, suffer from some optimization issues primarily in the form of inefficient database modeling; SQL queries and JavaScript code although testing has shown that these shortcomings do not hamper overall performance to such a degree that usability is compromised. Further usability testing performed on the system with five test subjects shows that a high level of overall user-friendliness has been achieved even though some special features, such as the detailed report containing price information per product for each store need to be improved.It is not possible to say at this time whether or not the designed system will be able to compete with existing ones or if the very concept of food price comparisons per se is viable in terms of profitability and marketability.

Today's Swedish large-scale forestry uses almost exclusively computer-aided bucking. It allows the harvester computer, using an optimisation price list (steering price list), to maximize the value of each tree. The optimisation price list can be adjusted so that the industry gets the raw material it demands from the forest. There are various simulation programs that can be used when constructing a optimisation price list. The simulation program merchandise a database of stem shapes using a given price list and mimics a harvester's work. To get the demanded raw material for the industry it is important to use a well-adjusted optimisation price list.

The great debate topic in media and among real estate agents in spring 2011 wasspecially reduced prices. Specially reduced prices means that a property is advertised at a considerably lower price than the evaluated current market value of the property. This is to attract more bidders in a potential bidding. It is in this case not completely established by law what is meant by considerably lower price, why this concept is difficult to interpret. Real estate agents got lot of criticism due to the output prices which were too low compared to the final prices.

An industry in distress was the breeding ground for a noted pricing strategy, labeled name-your-price. The industry was the music industry and the pricing strategy bears reminiscence of how medieval buskers earned their living during the dark ages; by letting the customers decide how much the good was worth, embodied by a thrown coin into a hat or similar collector. Translated into the contemporary corporate environment of today, where technical innovations provides access to the intellectual property for free, a few mighty economic actors have once again turned to the strategy were it all started; letting the customer set the price. The hat has been replaced by a box for your credit card number and the live music by a MP3 file, but the similarity is striking. The business model have been applied in other industries as well with various levels of success, thus the purpose of this thesis is to set up a framework for where the name-your-price strategy is applicable.

The purpose of this study is to examine which factors played an important role in the food price crisis of 2007-2008. Theories used are Microeconomic theory, explaining changes in supply and demand, and Macroeconomic theory, explaining the impact of changes in exchange rate on prices. A theory regarding speculation is also used to explain the impact of speculative activities effects on price. The method used is multiple regression analysis in order to determine the effects which ethanol production, oil price and dollar exchange rate had on the surge in the price of corn, rice and wheat.The data used is in monthly observations during the period 2005-2008. However, other factors are taken into consideration during the study, such as production quantity, stock size, economic growth, speculative activity and population growth.

In this paper the discourseand social practice of the Swedish culture funding system Skapande Skola hasbeen mapped out and examined. The material for analysis was takenfrom regulating documents, information texts and media texts, and alsofrom four interviews that were conducted. The theoretical foundation is builton theories from Pierre Bourdieu, Michel Foucault and the theoretical frameworkof New Public Management. The survey has resulted in three major points ofinterest. They are presented throughout the text.

In 1993 the internal market within the European Union was formed and ensured free movement of goods, services, capital and people. This led to the removal of trade barriers between members of the European Union. When opening up for competition, price differences between countries decreased and more jobs were created. A single currency was introduced by eleven countries in 1999 with the goal of reducing transaction costs, eliminating exchange rate risk and to further simplify trade. In 2001 Greece joined the collaboration and introduced the euro.

Many studies have shown that unethical acting can affect the share price of the company negatively. However, this is not always the case. The aim of this thesis is therefore to examine what it is that can cause the share price to be affected negatively by unethical acting exposed in media. This qualitative study is primarily based on interviews with institutional investors, but also with economic journalists and investor relations managers. Our conclusion is that there are three main reasons why the share price can be affected by unethical acting, namely economic consequences, the management's behaviour and psychological factors.