Rheumatoid arthritis is an autoimmune disease, where joints are attacked by the own immune system, leading to chronic inflammation and destruction of bone and cartilage. Inflammation is a complex process, controlled by many different substances. One of them is adenosine, which has anti-inflammatory properties. In this project, three polymorphisms in different genes, involved in synthesis and signaling of adenosine, were genotyped for 188 patients with RA and 362 controls without RA. The results shows that for the polymorphism in A2a, a gene coding for an adenosine receptor, there was no significant difference in genotype distribution between the groups.

Background: Sleep-disturbances in persons with Alzheimer´s disease are prevalent. They are characterized as increased frequency and duration of awakenings, decreased slow-wave sleep, REM-sleep and increase of day-time napping. Depression and lower quality of life are associated with sleep-disturbances. Altogether a significant source of stress for caregivers and an important factor in institutionalization. Non-pharmacological treatment alternatives are rare.Method: Single-case A-B-C design, with non-concurrent multiple baselines, a pilotstudy.Aim: To explore if an educational program on sleep, sleep disturbances and behavioural change directed towards caregivers improved sleep, depression and quality of life in persons with Alzheimer´s disease living at home.

SummaryPatients with burn injuries involving more than 20 percent of the total body surface area lose a lot of fluid and are in the risk of developing a severe hypovolemia. Fluid resuscitation is a corner stone in burn care and is important for preventingfurthercomplications. The most common resuscitation formula is the Parkland Formula. Hourly urine output is a measure used to evaluate if the fluid given is sufficient enough to maintain a sustainable tissue perfusion. Inhalation injury, abuse of alcohol and drugs are some of the factors that may increase the amountoffluid needed.

My purpose with this paper is to investigate how yong girls with immigrant backgrounds experience the social citizenship.I have focused on civil rights and obligations but also on the experience of access to education, employment and social community.Finally, I have chosen to look at the social citizenship from a gender perspective..

Patienter som är inlagda på vårdavdelningar på sjukhus har olika upplevelser av rummets utformning och inredning. Vår erfarenhet är att patientrum har vita väggar, textilier med diskreta färger och inga tavlor. Vad kännetecknar en utformning och inredning som är hälsobringande för patienten? En omgivning som människor är tillfreds med skapar balans i tillvaron och stärker det psykiska välbefinnandet och den fysiska hälsan. En viss form av arkitektur kan också bidra till uppkomsten av stress.

The purpose of this essay was to in a specific project for unemployed youths between 18 and 24 years, from an ecological point of view, examine how the youths experienced their unemployment and also to compare the purpose and structure of the project with the participants' experience.Important questions in my essay were how the unemployment affected the youths' identity and social circumstances, if the participants found the project meaningful, and experienced that they could influence how the project was formed, if the purpose of the project was in accordance with the youths' experience and how the ecological perspective could be used to understand the situation of the youths.To answer these questions one interview was made with one of the employees and five interviews were made with participant youths.The results of the essay was that the youths' experience of the project were very much individual. All of the participants found something in the project meaningful and most of them thought that it was possible to influence the project in some way. Something that both the youths and the employee pointed out as important was the employees and their supporting role..

Background: Many elderly are feeling lonely and insecure in their homes; it?s difficult for them to cope with their life situation after discharge from hospital. There is therefore a need to get a deeper understanding of their situation and the need for action, thus possibly preventing a new hospital admission. Recent research shows that a better coordination is necessary when elderly are discharged from hospital and that the quality of the discharge is essential for how they cope at home afterwards.Purpose: To get a deeper knowledge of older people´s experiences associated with frequent readmissions to hospital.Method: A qualitative research approach was used trough interviews with open questions. Ten persons with an age of 75 years and older who had a readmission to hospital within one month was interviewed.

This thesis investigates how web agencys in Stockholm use, value and incoroprate the terms usability, user experience and interaction design in their work process. The purpose of this study is to investigate how creative professionals works with the notions of usability, user experience and interaction design with focus on the end user. Our definition of creative professionals is every employee at a web agency involved in the work process of developing digital artefacts in any capacity. We wanted to investigate how these notions are considered, consciously or unconsciously, during the workprocess. Semi-structured interviews were conducted at three different web agencys with eight different employees.

Since 1999 auditors have an obligation, according to 42-44 §§ aktiebolagslagen (2005:551), to report suspicions of crime. The obligation to report means that the auditor is legally obliged to report any suspicious economical crime potentially committed by the executive director or a member of the board to a district attorney. Prior to the enactment it was almost impossible for the auditor to report any criminal suspicion due to the professional confidentiality. According to Ekobrottsmyndigheten the number of crime suspicion reports filed by auditors has reduced by 50 percent in the Stockholm-region between 2006 and 2010. However, after the enactment crime suspicion reports increased successively each year.

Arbetet handlar om hur man som höft och knäopererad patient känner sig bemött på en ortopedisk vårdavdelning efter att ha fått en protes inopererad. Dessa operationer kan i efterförloppet vara mycket smärtsamma och behöver i regel lång rehabilitering, vilket ställer stora krav på personalens sätt att vårda och bemöta patienter i postoperativt skede.Syftet är att beskriva hur patienter efter höft och knäprotesoperationer upplever personalens bemötande på ortopedisk vårdavdelning.En litteraturstudie är gjord utifrån kvalitativa artiklar som har bearbetats och analyserats enligt Evans metod som utgångspunkt för ett deskriptivt resultat.Resultatet presenteras utifrån tre teman; Att känna sig bemött som en unik individ: som skildrar patienters upplevelser av hur personalen tillgodoser varje enskild patients behov. Att känna sig professionellt omhändertagen: beskriver hur patienter känner när de blir väl omhändertagna under sin postoperativa tid på avdelningen. Att känna sig förbisedd: beskriver att patienter känner sig försummade och negligerade under sin postoperativa tid på vårdavdelningen. För att patienter med höft och knäproteser skall uppleva vården som positiv diskuteras vikten av att sjuksköterskan ger god information till patienten, att hon får fortlöpande utbildning och att vårdpersonalen arbetar med etiska reflektioner..

The purpose of my study was to examine how teachers in physical education experience different frame factors impact on their outdoor education and their choice of didactic approach. My study is based on Lundgren´s frame factor theory and Peitersen´s didactic learning model. I have used a qualitative research method to answer my questions. I have been using semi-structured interviews to interview six PE teachers who all teach at high school level.Based on my results we see that the teachers experience teaching hours and class sizes as the frame factors that mainly affect the outdoor education. Teachers often choose to split up the outdoor activities into sequences in order to achieve better learning.

Success in treatment with platinum-based chemotherapy against different types of cancer tumors is limited by side-effects such as hearing loss which can have a large impact on the individual`s quality of life. It is of great importance to continue with studies that address this complex of problems.Objective: The aim of this literature review is to investigate the impact of platinum-based chemotherapy on hearing in children and adolescents treated for different types of cancer.Method: A descriptive review of literature was made based on sources from 15 different studies on the impact of platinum-based chemotherapy on hearing in the target group.Results: The survey of the studies shows that platinum-based chemotherapy causes incidence of hearing loss by differing degree in the target group. Dosage of a platinum-based substance appeared to be the most significant factor. Treatment with both cisplatin and carboplatin was more ototoxic than treatment with only one of these. Greater risk for hearing loss was to a higher degree observed in younger children.

The purpose of this study was to examine the problematic and frustrating aspects of parenthood in the modern runaway world of today. In other words, we wanted to study how parents in Sweden experienced their life as parents in the beginning of the 21th century.We wanted to find answers to the following questions:What kind of problems do parents experience and how do they deal with these problems?What would parents consider to be typical for them as parents compared to how they remember their own parents?What do parents think about family politics?Do parents think they need parent education?If parents want parent education, why do they want it?To answer these questions we used qualitative interviews. With this method we got information from six parents and five professional parent educators who was kind enough to let us interview them. We also gathered information about the subject through literature and news articles.The result of the study can be divided into three parts.

Stigmatisering kring människor som lever med humant immunbristvirus (HIV) är utbredd. Patienter som lever med viruset har inte bara symptomen av infektionen att ta itu med, de måste också handskas med den diskriminering och de fördomar som finns. Tidigare studier har visat att kunskapsnivån om hiv är låg bland hälso- och sjukvårdspersonal och att de är rädda för att själva smittas när de vårdar hivsmittade patienter. Tidigare studier visar även att sjukvårdpersonal dömer människor med HIV på grund av fördomar kring människors bakgrund och livsstil. Syftet med denna studie var att belysa patienter med HIV/AIDS upplevelser av mötet med vården.

Well-functioning bicycle paths are relevant issues in today´s society as a way to increase active transport. Active transport means working for a better global climate, urban environment and public health. What we experience on a bicycle affects the choice of a bicycle path and is a subject where there is much left to explore. This essay examines methods in environmental psychology literature that measure the experiences of landscape. The aim is to find and apply methods to measure the experience of two bicycle paths in the Skåne plains.