It generally takes 10 to 12 years for a new drug to hit the market. The pharmaceutical industry invests huge sums in these early stages of research and development. In spite of the rapidly rising research and development expenditures fewer and fewer blockbuster drugs are being developed. Longer lead times and aggressive generic post-patent competition have narrowed the timeframe for the pharmaceutical companies to profit on their investments.In the face of these threats the pharmaceutical industry has developed a battery of strategies to prolong market exclusivity and to maximize return on investment. These emerging strategies are commonly known as Life cycle management (LCM), which actually is more of a concept than a method.

Den förtätade staden ses idag som en självklar del av en hållbar stadsutveckling. Vi lever i en urbaniseringstid och frågor kring hur vi kan skapa en förtätad stad av god kvalitet står högt på agendan. När allt fler människor lever i staden skapas ökad efterfrågan på samhällsservice i staden, som till exempel barnomsorg. I Sverige är det kommunen som ansvarar för att tillgodose medborgarna med denna service. Den svenska förskolan, som är den institution där detta behov till stor del ska tillgodoses, har i sin tur krav på god pedagogisk verksamhet samt en bra miljö för barnen, såväl inne som ute. Den här uppstasen handlar om hur förskolans utemiljö konstrueras i den urbana kontexten.

Storage of biomass is associated with problems like heat development, biomasslosses, and reduction of the fuel quality. Certain processes such as biological- andchemical degradation are responsible for these storage problems. This master?sthesis was carried out at Vattenfall Research and Development AB and is alignedtowards quantifying the biomass losses from short-term storage (1-2 months) ofbark and recovered wood. The biomass was stored in outdoor piles during differentseasons, campaign 1 (summer) and campaign 2 (autumn).

The study emanates from the national quality registry for persons with severe and profound hearing impairment. The aim was to examine possible differences between signing deaf and adults with acquired severe hearing loss, with reference to self-assessed problems, how the hearing loss influences daily life.In total 234 adults aged 30-90 years were included (128 women, 106 men). In the registry, there are background variables and questions that the patients have answered. The results, indicated on a visual analogue scale (VAS) from 0-100, from a question ?To which extent does your hearing loss at present influence your life?? were analysed.The study was performed by pooling the results of VAS and dividing the patients into signing deaf and those with acquired severe hearing loss, and in age groups 30-60 and 61-90 years.

Titel: Human being and Christian ? creationtheology of Gustaf Wingren.Analysis of an accentshift from a juridical theological metaphor to a biological theological metaphor.Author: Tove Pilroth.The purpose of the essay is to analyse the meaning and the consequences, in a critical and constructive way, of an accentshift of interpretation and understanding of the gospel, from a juridical theological metaphor to a biological theological metaphor. The purpose is presented in the frame of the creationtheology of Wingren. To be able to make the research and to answer the purpose of the essay, the following questions are essential:The human being is captive and redemption is liberation. If we are serious about that the gospel gives the human being rehabilitation, satisfaction, liberation and a life and a future with God, the essential question is which metaphor, a juridical or a biological, that speaks to the human being in the best way? What is the meaning of an accentshift from a juridical to a biological metaphor? How does the creationtheologhy of Wingren, from a biological metaphor, meets the situation of the existence for the human being, her longing for life, health and meaning? What kind of theological resources are present in the creationtheology of Wingren, in the confrontation with future theological challenges?The essay is stressing the need of pluralism in the interpretation of the gospel.

Background: When a child gets cancer it involves the whole family. The view of family focused care has change over the years. It has been shown that the family needs support to manage their life situation, when their child is ill. Aim: The aim of this study was to illustrate the family?s life situation, when a child gets cancer.

Concurrently with higher demands on comparability between companies, all Swedish listed parent companies are guilty to apply international accounting standards, IFRS/IAS, no later than January 1, 2005. In this thesis IFRS 7 Financial instruments: Disclosures, that treats information about financial instruments, is investigated. IFRS 7 aims to establish a good international standard for disclosures about financial instruments. The purpose of this thesis is to study differences in the interpretation of IFRS 7 Financial instruments: Disclosures between Swedish life insurance companies, problems ? if any ? that associate with the recommendation, the recommendation?s effect on accounting and the attitudes towards IFRS amongst the Swedish life insurance companies.

The aim of the study is to gain a deeper understanding of how young people's current identity is affected by their criminal background. We also want to understand the impact of resources in these young people?s social networks (that is their social capital) on their life course and formation and reformation of their identity. The theoretical frameworks used (as a tool to be able to analyze the empirical data) are theories of stigma, identity and social capital. The empirical study was conducted using semi-structured interviews that focused on questions about the life-story of informants.

Over the last decade the conversation on entrepreneurship has been both worldwide and intense. In Sweden, as in many other countries, this conversation has also concerned women?s entrepreneurship. Parallel with this conversation has been the debate on women in leading position in large corporations. This thesis aims to find out why and how women use entrepreneurship to handle existing conditions in life (such as the hardship of combining a traditional career with a traditional family life) and to create new conditions that suit them better.

This thesis, titled ?Change, choice and conditions?, is written by Lina Skantze and Bianca Zandén. The study explores the process in which individuals? attempt to end their criminal career, focusing on the interplay between path of life, choices, and conditions. The method is qualitative, and the empirical material consists of interviews with four young adults that all have experience of criminality.

Syftet med denna studie var att jämföra antalet anpassade utomhuslekplatser i Norrlands kommuner sedan 2001, och få svar på de ansvarigas uppfattning gällande tillgänglighet och anpassning, då tidigare studier visat på brister gällande dessa områden. Barn med funktionsnedsättning riskerar att uppleva social isolering och diskriminering om utomhuslekplatsers fysiska miljö skapar barriärer. Enligt funktionshinderpolitiken ska Sveriges allmänna platser och byggnader vara tillgängliga för alla år 2016. Metod: En enkätundersökning med mixad metod genomfördes där enkäter postades till de ansvariga för utomhuslekplatser i Norrlands 54 kommuner. Resultat: Resultatet jämfördes genomgående med en studie från 2001.

The aim of this study was to examine former criminals? experiences of help and support of importance to leave a criminal life style. The study consists of six interviews with former criminals and earlier studies on the subject. These studies show that relapse in crime are most common among those who are socially excluded from society. They also show that important factors to end a life in criminality are for example a supportive social network.

This study is based on interviews with heads of unit, care staff and senior representatives from a total of six people. We have in this study directed our focus on care quality in the elderly as a concept in development. It appears, when the elderly do not have any dependents, it is even more important that staff supports some extra where no relatives are involved.Quality of life is the broader concept of good quality care and where a good quality of care is a necessary condition for a good quality of life. According to the social services care is the target that older people will live a good life and be allowed to live in a safe environment, which we intend to investigate in this study. Opportunity for greater influence should now be given to older people and their families on how interventions should be designed and implemented.

This is a final thesis on the landscape architecture program at the Swedish University of Agricultural Sciences. It is the end of five years of studies and comprises 30 ECTS. This thesis is about the camp area Sjöröd, located by Gyllebosjön (the Gyllebo Lake) on Österlen in Skåne, southern Sweden. The thesis results in plan for how the area could be used in the future. It also raises the questions; what scouting of today is, how it is to be developed for the future, what a camp is and which aims the scout movement has set up for itself and its activities. The thesis also treats what is typical for Skåne, for Österlen and for the area around Sjöröd as a starting point.

In todays society sports has become a major part in people?s life, with the emerging of professionalization it?s become a thriving business that generates big money. An outcome of this evolution of sports as meant that most athletes must put more time and energy in to their athletics to have a chance to reach their dreams of being a professional athlete. And if an athletes dream get cut short somehow, the process of moving out of sport has been shown to somtimes be a difficult process for athletes that don?t have anything to fall back on.