In this project a LC-MS-method for the analysis of gamma-hydroxybutyrate, gamma-butyrolactone, 1,4-butanediol, amphetamine and methadone was developed.Initially, the efficiency of the ionisation of the analytes was evaluated with respect to the ionisation technique (ESI, APCI and APPI) and the composition of the mobile phase. In the next step a number of different columns was tested in order to find the one with the greatest potential for separation of the substances in question. Using the selected column, the separation was optimised by means of experimental design and the software The Unscrambler 7.8. The parameters studied were the flow rate, the column temperature and the mobile phase composition. The response variables were the resolution between the target compounds and the retention time of the last eluting compound.These experiments showed that, in order to obtain the best ionisation, the mobile phase should consist of 5 mM formic acid in water and acetonitrile.

One of the most discussed archaeological subjects is the neolitisation, and the start of a neolithic lifestyle which is characterized by several significant events. The traditional view has been that settled people were cultivating and breeding, but this picture has been questioned and changed in later years. The development is principally based on two models; that already neolithic people immigrated and took over, or that the new lifestyle gradually developed out of the existing cultures. Southern Scandinavia was characterized by a settlement pattern with permanent settlements which were complemented by temporary special settlements, but in time more domestic settlements originated. On the British Isles the settlements didn´t consist of permanent agricultural settlements but instead did the people here move freely between several short term settlements.  .

This report is the result of my examination work in Textdesign at Mälardalen University, Eskilstuna. The purpose with this work was to develop an accessible information material for the target group ?normal bowlers? that gives them the information they need to make their own decision on the lanes, because they often miss a coach during an away game. The focus was to target adjust the material through the theories readability, legibility and reading value, together with the method qualitative interviews. The result became a tested information booklet about how to read a lane pattern paper with additional information within the subject..

The purpose of this study is to observe which method that is used when it comes to teaching geometry. The study aims to take a closer look at four different ways of teaching: illustrations, using practical objects, brainstorming and verbal communication. The method used to get the results is observation. With the result, we can deduce primarily that the educators make use of the four didactic methods to varying degrees. There are similarities between most of the teachers but also differences between them.

In this study the practical work with the EU Water Framework starts on the island of Gotland. 33 lakes and 32 streams have been characterized and classified regarding to their ecological status. The aim with the characterisation is to create a uniform discription of all waterbodies and a comparable estimation for the future. The aim with the classification is both to study the waterbodies ecological status and to gain knowledge of where the resources should be concentrated so that the ecological status in all waterbodies will be good in 2015.The characterisation has been done according to the EU Water Framework Directive, and the factors that have been applied are the mean depth and area of the lake. The length and size on the catchment area are the factors that have been used on streams.

The purpose of this paper is to interpret two stories of creation and compare them to each other with focus on the gender perspective. The interpretation is generally limited to the creation of mankind and how women are represented in each particular story.  The stories I?m interpreting is the story of creation from the Holy Bible, the so called genesis, and from The Nag Hammadi Library?s story of creation called On the origin of the world. I want to show the difference between these two stories when it comes to the women?s position and in what level she is described.

The purpose of this essay was to identify the primary stakeholder in aid organisations, by which we mean whom they make their annual report for, and to analyse if there were any differences considering the design of their annual reports depending on which their primary stakeholder is. The method we used to explain the choice of primary stakeholder and the differences in the annual reports was a multiple case study. The collected data came from telephone interviews with 23 representatives from aid organisations and a review of annual reports. The results were analysed through pattern matching. We found that aid organisations do not have a primary stakeholder as in incorporated organisations.

Studies in the field of interaction design and the human memory claim there can be positive effects on the memory when information is presented for the user as a graphical pattern rather than a series of numbers. This thesis aims to influence designers to choose graphical patterns as an interface for information display. Low-fi and hi-fi prototypes of graphical patterns were constructed and tested in a variety of configurations by two users. The users showed differences in the ability to memorize a sequence of digits depending on how this sequence was presented. This study suggests that users are more easily able to recall information presented via a graphical user interface than when the same information is only presented digitally..

Swedish sawmills of today suffer from unsatisfying economy with high costs and low benefits. The economical result depends on how well the sawmill can use their raw material. Iggesund Timber AB, a sawmill in the Holmen group, produces a large amount is enduse orientated products for the woodworking industry. Therefore the aim of this student thesis was to investigate the possibility of automatic enduse orientated quality grading of Scots Pine (Pinus sylvestris) saw logs by using a gamma-ray log scanner. Iggesund Timber AB has the possibility to grade logs automatically with TINA, a two way gamma-ray log scanner. Grading and classification of Scots Pine logs in Sweden today are mainly manual but can in some rare cases be automatic.

The catchphrase this project has been; the boundaries between ornamentation and improvisation are fluid.My aim was to focus on my work process, giving me the space and time so develop my design further regarding shape, color and combination of different styles in patterns.This is an explorative project where patterns were created without a predetermined product of which the patterns would be applied. In a later stage the character of the pattern determined which product that would be most suitable for application.It resulted in a collection of patterns for wallpaper and clothing. The motives are foxes, geometrical shapes and squares from a notebook. These motives form an ornamental expression in the patterns with the purpose of embellishment and therefore increase the emotional value of the product..

Maternal behaviour is crucial for the development of the rat pups? behaviour and stressresponses later in life. There are numerous studies evaluating the effects of the dams?behaviours on the pups, but not many addressing what can be made for wellbeing of the ratdams when breeding. Few studies have addressed the question of how the commonly usedrearing environment effects the dams? behaviour and in the long run how it effect the ratsreared to become our research models.

This study was conducted in the "Kåtaberget" forest reserve in Västerbotten in the summer of 1999. In the summer of 1995, a prescribed burning was performed in the reserve. In some places where coarse dry woody debris (logs and stumps) was present, the fire consumed the wood, as well as parts of the humus layer, creating deep-burned patches. The low intensity ground fire also created dead woody debris by burning off living trees with open fire scars, as well as standing dead trees. In this study, the post-fire tree seedling establishment was examined, with special attention given to the former presence of woody debris. The study also includes a survey of the areal extent of deep-burned patches, as well as an examination of tree seedling establishment in these patches, compared to other burnt ground.

Amyotrophic lateral sclerosis is one of the major neurodegenerative diseases, causing an ascending paralysis that usually kills the patient within a few years from disease onset. The motor neurons show aggregates of proteins which in approximately 20 % of cases of the familial form contain mutated SOD1 protein. Trehalose is a disaccharide which has been shown to reduce protein aggregation and increase viability in cell models and alleviate symptoms in animal models of several neurodegenerative diseases associated with protein aggregation. When given orally to the SOD1G93A mouse model of ALS, trehalose failed to slow down the disease progression, which has led to questions about the uptake and distribution of the molecule in this mouse strain. The aim of this study was to investigate whether significant levels of trehalose reach the central nervous system of the SOD1G93A mouse after oral administration. This was performed by a trehalose assay of the brain of trehalose treated animals. A glucose assay was optimised for use in small samples of brain lysate after the digestion of trehalose into glucose by trehalase, and the difference in glucose concentration before and after digestion represented the trehalose level.

One way of signalling commands to the horse during riding is through applying tension on the reins to create bit pressure in the horse?s mouth (Terada et al., 2006; Clayton et al., 2011). The skilfulness of the rider in using the hands when applying bit pressure has consequences both for the horse?s performance and welfare (Manfredi et al., 2010). At the trot there are large vertical deviations of the horse?s body which the rider must adjust and adapt to (Terada et al., 2006) and an unsteady hand due to inability to follow the horse?s movement can be a source of discomfort and conflict behaviour in the horse (Heleski et al., 2009).

This report is about how accessibility in Eskilstuna's central trade street Kungsgatan can be improved, based on my background as spatial configuration designer, and by Eskilstuna's residents' opinions. In this report I explain what methods I have used, and how I attained my results. The goal of this project was to create ideal accessibility in the central part of Kungsgatan in Eskilstuna. Since Fristadstorget was rebuilt, and since the city is growing in terms of housing and residents, accessibility will in the near future be even more limited for visitors than it is today. My design proposal is designed based on street conditions, residents' opinions and Eskilstuna's existing ideas..