The main objective of this study is to divide a number of colorectal cancer cases into subgroups based on their molecular features using cluster analysis. The data used is supplied by a research group at Pathology, the Department of Medical Biosciences, Umeå University, and consists, after some preparation, of 455 observations which is a larger data set than many similar studies. The molecular variables that the clustering is based on are CIMP (CpG Island Methylator Phenotype), MSI (Micro Satellite Instability), BRAF- and KRAS-mutations. These are categorical variables and consequently the clustering method used is PAM (Partitioning Around Medoids) which is particularly useful with data on diverse variable level. The final analysis results in four subgroups that are represented by different combinations of attributes on the aforementioned variables.

The purpose of this essay is to try to understand the relationship between the structures of modern working life and the development of burnout. By using the method of qualitative interviews we wanted to see if the Effort-Reward Imbalance Model could be applied to the data we had collected. Two questions have been highlighted in our research:        ? Is it possible to establish a relationship between the structures of modern working life and the development of burnout among the subjects interviewed?  ? Is it possible to explain the development of burnout among our interviewed subjects through the Effort-Reward Imbalance Model?    Our theoretical frames are the general theories of the modern society and the modern working life as developed by Anthony Giddens, Ulrich Beck and Zygmunt Bauman. We have also used Johannes Siegrist?s medical-sociological Effort-Reward Imbalance Model (ERI-Model).

The aim of this study about wind power planning in forest was to examine the factors and restrictions, which represent technical limitations, biodiversity, tourism and amount of energy for wind farms in Kronoberg County. Suitable areas for wind power were identified from the collected information about planning principles and potential conflicts. From the suitable areas the potential energy gain is calculated. Methods used were mainly a literature review, interviews with experts and practitioners, GIS analysis and a rough calculation of the energy gain. The section of information and facts describes in general wind power planning and possible conflicts.

The purpose of this study was to find out how special needs users ' autonomy and influence in their daily routines is described by their assistants. What interpretations of the concepts of self-determination and influence on special needs users' daily routines emerge from the assistants statements and what conditions can be seen? To reach a conclusion, focus group as a method was used. The focus group met twice to discuss this topic. The diamond method was used as stimulus material to support the discussion in the focus group.

To introduce a standardized component assortment takes a lot of effort in order to make real cost savings. The rationalization effect itself is important, but perhaps even more important is to state the aim of the standardization efforts in a well-defined way. How can an organization assure that they are working in a proper way? How do they know that their efforts are being interpreted into the whole organization? And, how do they know that the standardization efforts actually save money? Different components differ heavily e.g. in technical complexity and quality issues.

Transportation of pigs might be a welfare problem. Stress during and after transportation can negatively affect the meat quality or cause carcass damages, which leads to major economic losses every year. The transportation chain can be divided into several stages; loading, transport and unloading. This literature review focuses on unloading of pigs from a transport. When arriving at an abattoir pigs can be fatigued and need to be as smoothly unloaded as possible.

Vid starten av idrottsundervisningen på 1800-talet fanns en problematik gällande lokalbrist. Denna problematik fortsatte och aktuell forskning visar att endast 70 % av Sveriges skolor i början av århundradet hade regelbunden tillgång till en gymnastiksal eller idrottshall. Kopplat till denna problematik saknas forskning kring huruvida det finns tillfredsställande redskap till förfogande eller ej. Därför syftar denna studie till att undersöka vilka lokaler samt redskap, fasta och lösa, som idrottslärare har till sitt förfogande i undervisningen och i vilken utsträckning de har det. Denna studie baseras på en webbenkät som har skickats ut till idrottslärare för att uppfylla syftet.

Transportation of pigs might be a welfare problem. Stress during and after transportation can negatively affect the meat quality or cause carcass damages, which leads to major economic losses every year. The transportation chain can be divided into several stages; loading, transport and unloading. This literature review focuses on unloading of pigs from a transport. When arriving at an abattoir pigs can be fatigued and need to be as smoothly unloaded as possible.

Introduction: Breast pain, mastalgia, is a common problem for many women. The pain can cause so much concern that the woman seeks help in health care. The cause of concern is often that that the pain may be due to breast cancer. Women with mastalgia are referred for mammography to investigate the cause of the pain. Experience says that the mammography is mostly normal.Aim: The aim of the study was to get an overall picture of the results of the mammograms performed on Mammography SU / Sahlgrenska in 2011.

Project Safe Sleeping Position (SSP) contains all parts in a product development phase. The project comprises the whole cycle from idea to a complete product where all aspects are included. The scope is to develop an innovative solution for a common known problem and work with all parts within the man-machine-way. The result is an inflatable product which secures a child in the correct way for the seatbelt to work properly in the rearseat of a car. Ergonomics, technical extent, usability, design, construction, product solutions and market potential are some of all parts witch the project includes.

The graduation essay has been carried out in co-operation with Kalmar Industries in Lidhult, Sweden. The purpose of our essay was to develop a complete construction solution on a hoist that could lift a laying wheel, lift it up and then turn it 90 degrees. After that the wheel shall be placed in a special holder.The background of the essay is a record of reports of damage wheels when they been incorrect lifted with a forklift. The hoist shall be used together with the same forklifts that manage the wheels today. Together with our instructor at Kalmar Industries we developed a requirement specification and from that we got free hands.However this was not the main task from the beginning, then a simular hoist should be develop but used directly in the assembly workshop without using a forklift.We started to find principle solutions that later was evaluated against the requirement specification.

The purpose of this paper is to describe how librarians andusers think of electronic books in libraries. My questions are:-What are electronic books, and how do they work?-How has electronic books been implemented by librariansin the libraries and on the libraries? websites?-How do users describe their view of electronic books?-How do the librarians and users think of electronic book inthe future?To be able to answer these questions I have studied relevantliterature, made qualitative interviews with two librarians attwo similar libraries and I had dialogues with several usersElectronic books were introduced 2002 at the two libraries.In the beginning the libraries made different types ofmarketing, but today they only have the website withinformation. Their purpose was to try this out and offer theusers a new media. So far, there are few users who borrowthese books, and maybe it depends on technical conditions.According to the dialogues I had, most of the users have noidea what electronic books are.

Background: Breast cancer is one of the most common types of cancer in the world and it usually affects elderly women. However, there are between 600-700 cases per year in Sweden where women under the age of 45 are diagnosed. Removal of the breast or part of the breast, hair loss, fatigue and nausea as a result of the breast cancer treatment has an emotional and physical impact on the women?s lifeworld. The nurse should build a relationship with the women to identify and meet their needs. Aim: To describe younger women?s experiences of getting a breast cancer diagnosis and life afterwards.Method: Four biographical books were analyzed to match the aim of the study.Result: The findings were that the women experience similar thoughts and feelings when it comes to living with a cancer diagnosis.

The implementation of large IT-systems is a complex area where many aspects have to be taken into account.KSU, Kärnkraftssäkerhet och Utbildning AB, is a small company in the Vattenfall group that is increasingly being urged to implement SAP, one of the largest ERP-systems on the market. Vattenfalls purpose with SAP is to centralize certain processes within economy that are common to all the companies in the group, this to gain benefits with economics of scale. However, KSU is not convinced that SAP is a suitable system and that the common processes apply to them.The purpose of this degree project is to investigate if SAP is a suitable system and if KSU will benefit from a transition to SAP. Three perspectives were applied to further specify important areas of the main question. From a technical point of view KSU:s demands on a system was mapped against SAP.

Syftet med uppsatsen var att studera hur Försvarsmakten bör organisera, utbilda och träna ett skyttekompani i framtiden inom några områden. Den skall med hjälp av några av de grundläggande förmågorna ge svar på hur vi organiserar, utbildar och tränar idag samt analysera om några förändringar bör ske för att skapa ett bättre förband.Den teoretiska grunden för uppsatsen har varit de grundläggande förmågorna; ledning, rörlighet och uthållighet. Uppsatsen har tagit sin utgångspunkt i bland annat Arméns utvecklingsplan och studien Verkan Mot Markmål. Litteraturstudier har även genomförts av andra studier och dokument. Även två stycken intervjuer har genomförts för att belysa dagsläget respektive framtiden för ett skyttekompani.