Clopidogrel is an antiplatelet substance that prevents blood coagulation in the arteries. It is an inactive pro drug that becomes activated after first-pass metabolism by the liver. The active metabolite of clopidogrel is 2-oxoclopidogrel, which is unstable therefore pharmacokinetic data is obtained by measuring the inactive metabolite clopidogrel acid in plasma. Clopidogrel is taken orally in tablet form. The aim of this project was to develop a LC-MS/MS method for quantification of clopidogrel and its metabolite in plasma. The method has been developed by optimizing the sample preparation.

An increasing number of applications are becoming more or less network based today.The traditional architecture for network based applications is client-server, but as usageof download services are going up, so is the Peer-to-Peer architecture. This report is acomparison between the Peer-to-Peer and client-server model, and can serve as a basiswhen a decision between them needs to be taken. In the report, the performancebetween the different architectures is compared in different contexts. Our basis is ageneral implementation of both architectures in a test that is derived from a previousreport. On top of this, the performance of the different architectures are measured,implemented in a gaming-context.

Älander, Eva (2011): De nationella proven i svenska ? hur påverkar de undervisningen i årskurs 9? Examensarbete i didaktik. Lärarprogrammet. Akademin för utbildning och ekonomi. Högskolan i Gävle. SammanfattningDetta är en studie om det nationella provet i svenska för årskurs 9.

The state of health in Sweden demonstrates a high average length of life at the same time as diseases, due to luxurious living, grew into more and more widespread public health problems. Finding out that information is not enough to get man to live healthy has been conducive to a pedagogic based health education. An illustration of such an education is Public health pedagogy at the University of Kristianstad. The question is, does this education correspond to the new claims that society lays to health work? Our purpose was to throw light upon how individuals, qualified as public health pedagogues, look upon their work on one hand and how different clusters of thought from their study programme are conceived as activated in their professional exercise on the other.

Inom offentlig sektor blir det allt viktigare med marknadsföring och varumärkesbyggande. Viktiga kommunikationsfrågor handlar om att informationsspridning har en stor roll i hur pass bra en kommun kan uppfylla kraven från invånarna. För att uppfylla kraven kan kommunens förvaltningar samarbeta i frågan om information, kommunikation och marknadsföring valet av kanal för dessa är en viktig del. Syftet med uppsatsen blir därmed att ge rekommendationer för kommunikation, information och marknadsföring till Emmaboda kommun. Rekommendationerna ska ge marknadsgruppen för Emmaboda kommun en bild av vilka kanaler som är mest lämpliga att använda i arbetet kring informationsspridning.

The security solutions used in wireless home networks are examined in this report. Thegrowing number of wireless units have increased the need for reliable security solutions.This report aims to enlighten the reader about the fundamental technology used inwireless security solutions and inform about the existing flaws. A recommendationabout how to achieve a high level of security in the home network is also given to thereader.Several flaws in the security solutions in use have been reported. Of these the mostsevere has been examined in a test network using highly accessible tools to get aperception of how vulnerable the user is.The tests showed that several attacks were efficient and easily carried out. We have alsoseen that several of the home networks in our sample are susceptible to these attacks.Our survey revealed that the Internet service provider's technical support in many caseslacked the knowledge necessary to inform the user about reliable security solutions..

A number of studies have been made to examine several aspects of voice production in individuals with different types of hearing impairments. Most of the studies were made to explore the impact that hearing aids have for people with severe or congenital hearing impairment. So far it has been confirmed that there are changes regarding voice production in these individuals. A group that has not been investigated regarding voice production to a larger extent are hearing aid users with an acquired hearing impairment. In the present study the voice production of seven individuals, four men and three women, with a moderate acquired hearing impairment is examined.

According to some researchers, dyscalculia is at least as prevalent as dyslexia. Somewhere between 3.6-6 % of all pupils have specific mathematics difficulties named dyslexia. If this be true, it should present the most complex special education predicament by far in schools today. Despite the statistics, dyscalculia is still a rather unknown concept.The cause of dyscalculia is not yet fully analyzed. There are several theories and many researchers see similarities between dyscalculia and the special educational problem of reading and writing, dyslexia.

Syftet med studien var att genom en kvalitativ metod i form av fokusgruppsintervju undersöka högstadielärares upplevelser av elevers möjlighet till att förändra deras självförmåga (SE). Samt om lärarna bedömer att de genom sitt agerande kan påverka elevers SE. Som teoretiskt ramverk har Banduras (1986) teori om självförmåga använts. Resultaten visade att eleverna kunde både stötta och sänka varandras SE. Feedbackens utformning var stor påverkansfaktor för elevers SE samt hur den förmedlades.

Nimo Verken AB is the leading producer in the Scandinavia of drying cabinets. The construction has, with small changes, been the same since the 70s with a thermostat and a timer as controlling system. There was a wish to develop a modern cabinet which showed remaining time on a display and with energy saving functions.In this report we go through how it is possible to implement a digital controlling system, where remaining time is shown on a display and where it is possible to choose a preset ?program?.The report first presents the fundamental theory for a PIC, where we describe the different registers, how interrupts are handled, the internal clock function and how data is sent to control the different parts of the construction.Next the report presents and describes the new hardware that is needed, such as the encoder, the temperature sensor and the display.After the theory we describe how the program in the PIC may be drafted. Last in the report we have the result of the tests of the temperature variations and the accuracy of the time..

Marknaden för sökmotorer växer och förutspås under 2006 att öka med 41 % till en mångmiljardindustri. Informationsmängden är i nuläget så pass stor att en enskild sökmotor inte kan indexera allt. Detta medför att behovet av specialiserade sökmotorer ökar. Vi föreslår i denna uppsats en specialiserad sökmotor för att hitta information med anknytning till en viss geografisk position. Vi kontaktade företag inom två branscher för att undersöka vilka framgångsfaktorer som skulle öka företagens acceptans av detta verktyg.

The design process of an interaction design student is mostly collaborative and computer oriented. Based on this, it?s hard to believe that we have not yet found a tool that will facilitate our needs. With this in mind, which elements do we need to promote collaboration in a virtual design process? This thesis will include design processes, collaboration, creativity and virtual awareness, amongst others.

This Master Thesis documents the development of an On Board Diagnosis (OBD-II) interface for remote diagnosis of vehicles. The Master Thesis is part of a project at the company Wayfinder Systems in Lund. The purpose of this thesis was to design a scantool that communicates with a vehicle through its OBD-II port using relevant standards. In order to make the OBD-II interface development easier, a car simulator was first built. Both the car simulator and the OBD-II interface were implemented using a linux computer running a C-program with serial communication with an external electrical interface.

Genomic selection (GS) is used for selection of breeding animals of dairy cattle. GS is though not as extensively used within the beef industry. One reason for that is the low accuracy (rTI) of the breeding value that is of great importance for the final genetic gain. Causes to the low accuracy are high effective population size, a small reference population and a genetically differentiated population. There is however a market for genomic selection with High Density (HD) tests for beef cattle.

Sammanfattning Syfte och frågeställningarSyftet med denna studie är att genom en systematisk litteraturstudie undersöka hur prepubertala barn rekommenderas att styrketräna och hur detta motiveras.1. Vilken träningsmodell ger enligt de genomgångna studierna störst styrkeutveckling hos barn?2. Skiljer sig de rekommenderade styrketräningsmodellerna åt för pojkar resp. flickor?3.