In vitro-test för upptäckt och behandling av tumör eller mikrometastaser har de senaste 30 åren gjort stora framsteg tack vare immunokemi och nya framgångsrika cellodlings- tekniker som bättre reproducerar celltillväxt i tre dimensioner (3D) och det omgivande stromat (multicellulär tumörsfäroidodling). TS1-218 scFv (single chain variable fragment) är en monoklonal antikropp som har affinitet till ett protein tillhörande cytoskelettet (cytokeratin). Av TS1-218 har skapats olika varianter (en dimer TS1-2182 och en mutant HE1-Q) med syftet att öka affinitet och retentionstid på platsen för dess verkan. I det här projektet försökte vi att testa och jämföra egenskaper hos alla 3 joderade antikropparna genom att inkubera odlade Hela Hep 2 tumörcellssfäroider med dessa antikroppar. Alla tre antikroppsvarianter visade god förmåga att penetrera sfäroider och att binda deras epitop i cytokeratin 8.

The aim of this Masters thesis is to examine the library discourses concerning the phenomenon and concept of digital libraries in Swedish library press 1980-2002. What changes can be identified? The questions are: what is said about the conditions for the phenomenon; how is the concept of digital libraries used; who makes these statements; what are the relations between these discussions and the library context in which they are made? Five Swedish library journals, BBL/Biblioteksbladet, DIK-forum, Human IT, Svensk biblioteksforskning and Tidskrift för dokumentation, were examined. The method used was discourse analysis. The theoretical starting-point was Foucaults discourse theory.

Many species and hence biodiversity depend on old, large oaks (Quercus robur) with hollow trunks. The populations of oak-living organisms have to migrate to a nearby old oak in order to survive the death of the host. The oak district south of Linköping, Sweden, is unique in area and the number of old oaks. It is anyway doubtful whether regeneration of oak will secure future continuity. Oaks are light-demanding and thrive in open pastures.

The purpose of this Bachelor?s thesis is twofold. Firstly it aims to make a contribution to the understanding of how five Swedish Diocesan libraries have carried out the digitizing of their rare book and manuscript collections. Problem areas related to this activity are also investigated. Secondly, it aims to examine the relative guidelines and standardization norms, which have been formulated on a national basis.

The most common form of hair loss in young and old people is androgenic alopecia. Hereditary hair loss affects both men and women. Hereditary hair loss in some women begins at the age of 30, but as a rule hair loss begins in post-menopausal women. In women the hair thins out in an oval portion of the front part of the scalp. In men, hair loss can start as early as at the age of 20.

In 2010, Airwatergreen AB started testing their new technology, the Airwaterwell, an atmospherical water generator of their own design that is running on solar heat, with a production capacity of three litres of water per day and m2. The purpose was to focus on foreign aid organizations as main purchasers for project investments towards rural communities in developing countries that suffer from lack of, or compromised quality of drinking water. In order to further understand if this technology would bring a positive impact in the developing countries, the company contacted the Swedish University of Agriculture for a socio-economic study of the Airwaterwells? potential. The authors elected Cost benefit analysis as the appropriate method for conducting the study and India became the study region because of its many problems with water related issues such as diseases as well as insufficient water supply for households. The regions that this study is based on are Gujarat, Haryana and Uttar Pradesh given their differences in income, health situation and poverty rate.

Hemoglobin is an oxygen binding protein in erythrocytes. Hemoglobin is composed of four polypeptide chains. During the fetal stage the type of hemoglobin called fetal hemoglobin (HbF) dominates. After birth HbF is replaced by adult hemoglobin (HbA). HbF persists in concentrations less than 1%.

Denna rapport beskriver skapandeprocessen av webbsidan aiducate.se, vars syfte är att stötta, motivera och vägleda gymnasieelever i sin utbildning. Projektet genomfördes självständigt utan någon uppdragsgivare och pågick under en tidsperiod om tio veckor. Till grund låg en förundersökning som visade på bristande motivation hos gymnasieelever. I en kompletterande enkätundersökning fastställdes det att eleverna önskade en modernisering av utbildningen med utrymme för nutida undervisningsmetoder. Som ett komplement till gymnasieutbildningen framställdes därför innovationen Aiducate som i framtiden ska omfatta olika verktyg för studierna.

Background: Nurses´daily has to face death and dying in their work with patients in a palliative state.  This means both emotionell and workrelated challenges. However nurses in this context are not experiencing more stress then others.Aim: The aim is to describe nurses´experiences of caring for patients in a palliative state.Method: A litterature review based on ten qualitative articles published between 2006- 2012. To collect data we used the databases Cinahl, PubMed, Nursing Allied Health Source and Medline. We worked with Fribergs (2006) model ?Contribute to evidensbased care with a base in analyses of qualitative science? in the analysis.Result: Four main themes were identified; The meaning of the nurses´ spirituality in the care, Why the nurse choose to work in this field, To be certain in the professional role and The meaning of the caring relationship.

Stress-related diseases in Sweden have doubled since 1997. Even longterm sickness related tostress has increased over the last decade. In future there is a need of alternative methods todecrease the amount of people being affected to gain a better population health. Natureassisted therapy (NAT) was shown to be a successful method as part of the therapy of stressand burnout likewise was nature an important factor to prevent people from mentaldisorders. The aim of this study was to analyse the latest research concearning nature and itshealth effects with focus on stress and burnout patients in order to plan health promotingactivities outdoors for these patients.

This study examines how the media reports on the Pride Festival in Stockholm and what news topics and themes it prioritizes. The purpose of this paper is to examine whether the media coverage of Pride highlights political questions related to social and societal problems. One of the main focuses of the study is on how the media covers male and female homosexuality. The newspapers examined are the tabloids Aftonbladet and Expressen and the respected dailies Dagens Nyheter and Svenska Dagbladet. The study extends over three periods: 19-07-2010 to 07-08-2010, 25-07-2011 to 14-08-2011, and 24-07-2012 to 11-08-2012.Several key theories and themes frame the study.

Background: There have been doping usage as far back as as ancient Greece and around the early 1900s started the doping we have today. In 2008 it was 22,000 men aged 15-54 years old who had any kind of experience with doping in Sweden. The problem of doping use are all over the world and to overcome this problem, we need to work across borders.Objectives: The purpose of this study is to investigate whether there is any connection between the use of supplements and attitude to doping. The study is based on the questions: is there any connection between the use of supplements and positive attitude to doping? is there any connection between the use of supplements/doping substances and high training frequency? and is there different use of supplement/doping substances between girls and boys?Method: A survey in form of a cross-sectional study and a waiting room survey was conducted with 63 respondents of whom 57,1% were women.

Mussel meal is a potential source of protein, with a good composition of amino acids, for laying hens and broiler chickens, and may replace the use of fish meal in organic poultry production. Lead and cadmium are heavy metals which occur in the environment and can be accumulated in mussels. When poultry are exposed to heavy metals, the metals are absorbed in the small intestine and distributed in the body in the form of ions, complexes or bound to proteins. In poultry, lead accumulates in bone tissue, liver and kidneys, while cadmium accumulates in liver and kidneys. Generally very low concentrations of these heavy metals occur in muscles of broilers which have been exposed to feed contaminated with cadmium or lead.

AimThe aim of this study was to investigate and describe qualified nurses? worries related to handling chemotherapeutic drugs, further is the aim to explore if the nurses comply with the guidelines at a haematological ward. MethodThe cross-sectional study uses a descriptive design and a quantitative approach to analyze nurses? worries at a haematological ward. The data has been collected through questionnaires which were handed out to 42 nurses at the haematological ward. The questionnaires included 17 questions that were designed by the authors of this study, and 32 nurses returned the questionnaire. ResultsThe majority of the nurses declared that they handle chemotherapeutic drugs once or more a week. The results of the study show that the nurses´ comply with the available guidelines are relatively good.

I detta arbete har uppfattningen av känslor via ambiensljud, effektljud och röst undersökts i en ljudberättelse. Detta har gjorts för att få en ökad uppfattning om hur ljud påverkar en situation och om det går att ersätta musiken som känslomässig anknytning till berättelsen.Ljudberättelserna är designade med tre olika känslor i fokus, glädje/lycka, stress/ spänning samt ilska. Analysen av dessa gjordes genom att intervjua 12 personer som sedan svarade på frågor baserade på Tuuris m.fl. tabell om ljuduppfattning. Därefter analyserades resultaten utifrån Michel Chions Semantic och Causal för att se var varje informant fokuserade.