Syfte: Syftet med studien var att beskriva unga människors upplevelser av att leva med en inflammatorisk tarmsjukdom (IBD), samt att beskriva hur sjukdomen påverkar livskvaliteten. Vidare var syftet att beskriva artiklarnas kvalitet utifrån den metodologiska aspekten urval.Metod: Beskrivande litteraturstudie baserad på 14 vetenskapliga artiklar, som söktes i databaserna Cinahl och PubMed via Högskolan i Gävle. Sökorden som användes var: Inflammatory bowel disease, Quality of life, Chronic disease, Experience och Adolescents. Sökningarna var begränsade inom publiceringsåren 2009 - 2013.Huvudresultat: De unga människorna upplevde många olika besvärande symtom som sågs som ett hinder till ett ?normalt? liv, och symtomen visade sig ha ett samband med ungdomarnas sömnkvalitet samt ångest och depression.

Användningen av biomarkörer inom medicin är ett viktigt verktyg för att ställa diagnos och fatta terapetiska beslut. Surfaktant protein D (SP-D) har visat sig vara en lovande biomarkör för perifera lungsjukdomar på humansidan och har därför även börjat studeras inom veterinärmedicinen. Surfaktant protein D är ett relativt lungspecifikt protein och produceras främst i perifera delar av lungorna, f.f.a av claraceller i bronkioler och typ II pneumocyter i alveoler. Det fungerar som ett akutfasprotein med liknande egenskaper som kollektiner och är därför viktigt för medfödda immunförsvaret. Förutom detta har det också visat sig vara grundläggande för normala lunghomeostasen genom att utgöra en beståndsdel i surfaktant. Mekanismerna bakom dess funktion i lungan är dock inte helt klarlagda. Eftersom SP-D är så basalt för lungan påverkas det ofta kraftigt vid perifera lungskador.

Rheumatoid arthritis is an autoimmune disease, where joints are attacked by the own immune system, leading to chronic inflammation and destruction of bone and cartilage. Inflammation is a complex process, controlled by many different substances. One of them is adenosine, which has anti-inflammatory properties. In this project, three polymorphisms in different genes, involved in synthesis and signaling of adenosine, were genotyped for 188 patients with RA and 362 controls without RA. The results shows that for the polymorphism in A2a, a gene coding for an adenosine receptor, there was no significant difference in genotype distribution between the groups.

Borna disease virus (BDV) is a virus with capability to cause neurological disease in several species of mammals and of ostriches. Also humans are suspected to be susceptible to the virus, as the viral RNA and antibodies against BDV have been found in some humans with psychiatric diseases, like schizophrenia and depression. In Sweden there is a disease called staggering disease in cats, associated to BDV-infection. This disease often has a fatal progress. Definite diagnosis is reached by histo-pathological and immunohistochemical examination of the central nervous system.

The aim of the study was to investigate how a significant other of threepersons with Parkinson?s disease experienced the communication in conversation. Astructured interview and analysis of a video recorded conversation was performed.The questions in the interview were aimed at mapping the significant others?experience of communicative problems, their frequency, degree and conversationstrategies used by a significant other in conversation. The result showed that thesignificant others? experienced problems in communication related to the disease inseveral different areas for two of three participants with Parkinson?s disease.

Lower urinary tract diseases are a common problem in cats all over the world. The symptoms are for example dysuria, pollakuria, stranguria, periuria and hematuria. In approximately two thirds of these cats the underlying cause is not known and the disease is therefore called feline idiopathic cystitis (FIC). We need to know more about the disease to get a consistently effective treatment and prevention. A retrospective study was performed in 50 cats with symptoms of FIC and where other causes of inflammation were ruled out. Data like breed, age, sex, body weight, feeding, therapy and therapeutic results were collected, also if it was an indoor or outdoor cat, duration of the symptoms, if there was any stress and if the cat was living with another cat.

Ear disease and hearing loss in preschool children can be difficult to discover and diagnose. This paper investigates ear disease in 20 children controls from 1 to 5 years of age. The aim of the study was to map prevalence and incidence for ear disease, and prevalence of hearing loss in a group of children.Twenty children wide aged 1, 1½, 3 and 5 were included and investigated according to a set protocol with psychoacoustic tests, tympanometry, ear microscopy and a parental questionnaire. The majority of the children could be evaluated by age adequate psychoacoustic tests and otoscopy. Tympanometry was the investigation method that was most difficult to perform.

Background: Alzheimer?s disease belongs to the largest group of dementia and stands for the half of those 37 millions persons whom are affected of dementia in the entire world. Alzheimer?s disease affects the patients with changes on their behaviour. It is important as a nurse to prevent that the symptoms increase.

Diseases associated with monocytosis in Swedish dogs - a retrospective study. The purpuse of this retrospective study is to determine which diseases are associated with pronounced monocytosis in Swedish dogs. Records of 153 dogs with monocytosis were evaluated. The most common cause was infectious diseases (49%) of which pyometra was seen in 23% of the cases, cystitis and fever of unknown origin each in 13% and gastroenteritis in 12%. Cortison treatment was the second most common cause with 29%. A sixth of the dogs had non inflammatory diseases such as neoplasia, renal- and heartfailure.

Background: Heart failure is a complex condition which means that the hearts capacity topump blood is reduced. The aim of this study was to investigate how patients with heartfailure considered their knowledge and the information they received about their disease andself-care.Method: Patients suffering from heart failure, hospitalized at section 30 E (n=13), andpatients visiting the nurse led heart failure clinic (n=4) at Akademiska sjukhuset in Uppsala,were requested to participate in the study. The patients answered questions about knowledgeand information concerning self-care and their disease. Data were analyzed using SPSS 15.0.Results: The patients valued their knowledge about the disease as lower than their knowledgeabout self-care. The study showed that all the patients found the information they hadreceived about their self-care better than the information they had received about theirdisease.

Establishing a reference interval for plasma fibrinogen in foals Fibrinogen concentrations were analysed in EDTA preserved blood plasma samples from 34 thoroughbred foals born in 2001 and 2002 at one stud farm. The foals were between 0 and 240 days old at the time of the sampling, and there were 19 fillies and 12 stallions in the group. The foals were examined for clinical symptoms of disease and their body temperature was measured before blood was sampled from the jugular vein. From totally 156 blood samples, 31 were selected as originating from clinically healthy foals, and used to determine a reference range for thoroughbred foals. Samples originating from foals showing clinical symptoms of disease or an abnormal body temperature at the time of sampling, were classified as coming from unhealthy animals.

The purpose of this study was to explore nurses' experiences of obstructed airways in the prehospital work.A qualitative interview study with a descriptive and explorative design was used. The sample consisted of nine registered nurses whereof three were women and six were men, with or without further education and varying length of experience in the ambulance service.Prehospital personnel builds up a vast plan of action based on the emergency information provided by SOS. Simple methods for managing obstructed airways were stated often enough. Problems with obstructed airways are considered so unusual that it never becomes a routine. Several factors affect the identification and managing of obstructed airways, both external factors and the different patient categories are considered important.

SUMMARYThis work consists of a review of the medical records of 142 horses that visited the Equine dermatology clinic, at the University Animal Hospital, UDS, at Ultuna, Uppsala, Sweden, between January 2007 and June 2010. The study answers certain main questions like clinical signs responsible for the visit, the most common diagnoses, their diagnostic procedures, treatment modalities and finally, the outcome of treatment.Among 50 diagnoses, four were predominant followed by additional 46 diagnoses, each presenting by few or, in many cases, only one horse. The most common dermatological problem diagnosed was Equine Sarcoid representing 18,3 % of the cases (26/142), which probably reflects the initiation of a Sarcoid treatment-trial in 2007, that resulted in an accumulation of sarcoid horses in the clinic .The second most common diagnosis was Atopy 12 % (17/142) followed by Allergy with skin affection 9,2 % (13/142) and Acute superficial pyodermia 4,9 % (7/142). If the horses were divided into diagnostic groups, the majority (34,5 %) belonged to HA5 group, (Immunological skin diseases), followed by group HA4, (Infectious and inflammatory conditions of the skin) (22,5 %) and HA6, (Neoplasia) (21,8 %). Traumatic skin injuries represented only 2,1 % of the cases, compared to 80 % of horses in the Agria insurance statistics for veterinary care.The most common clinical sign and reasons for veterinary consultation was pruritus (35,9 %), suspected sarcoids (17,6 %), alopecia (12,7 %), nodules (12 %), seborrea, scaling and crusts (9,2 %) and excoriations (5,6 %), respectively, followed by a scattered number of more uncommon symtoms.The diagnostic methods most frequently applied were cytology and biopsy, used in 41,5 % and 36,6 % of the cases, respectively.

The purpose of this study was to describe how adolescents aged 12-18 years with inflammatory bowel disease experience their illness and what coping strategies they use to manage their illness and improve their wellbeing. The method used was a descriptive literature study, and the result of the study included 15 scientific articles. Our results showed that IBD affected the adolescent?s everyday life and social life with friends, family and activities. The adolescents also reported that they experienced a feeling of vulnerability, altered body image and that they saw themselves as different from healthy subjects.

Studiens målsättning var att besvara tre frågeställningar. Skiljer sig andningsfrekvensmönstret efter ansträngning hos varmblodstravare med prestationsnedsättning från normalpresterande hästar? Påverkas andningsfrekvensmönstret efter ansträngning av en ökad slemansamling i luftstrupen? Är koncentrationen surfaktantprotein D i blodet en relevant analysparameter vid utvärdering av nedre luftvägsproblem? Hypotesen var att travhästar med subkliniska luftvägsproblem i de nedre luftvägarna har en längre återhämtningsperiod efter ansträngning jämfört med friska hästar. Kopplingen mellan ökad slemansamling i luftstrupen och prestation undersöktes också. 24 varmblodstravare deltog i försöket. Innan försöket undersöktes varje häst kliniskt inkluderande vilo-EKG och luftvägsendoskopi.