Transdermal drug delivery, besides painfulinjections with syringes, has long been associatedwith small size particle pharmaceuticals, which candiffuse through the skin. This method of drugadministration has only been applicable on a smallnumber of drugs, where active molecules are smalland delivery time should or can be long.Other drug delivery options are oral administrationand injection with hypodermic needles (ordinaryhospital syringes). In oral administration thestomach and liver tend to dissolve the drug and theeffect becomes more difficult to anticipate, anddrug delivery rates difficult to control. Hypodermicneedles are used as a mean of drug injectiondirectly into the bloodstream. This method ispainful and risks infection due to tissue damageand skin penetration.One way to get a painless non-damaging techniquewith high delivery rate that still can delivery largemolecules is to manufacture an array of microscopichollow needles and equip them with a pumping unitthat delivers the correct amount of drugs.This thesis shows the technique and possibility ofmanufacture micromachined needles using low costtechniques of Ion Track Technology (radiation ofheavy ions creates porous materials), electrolessdeposition (non-current activated wet chemistrymethod of depositing metal) and electroplating.

This literature study describes the ways in which the spread of rabies can be prevented in India, what guidelines are set and also which methods have proved most effective. Every year rabies causes the death of around 20 000 people in India, which makes the prevalence in the country the highest in the world. The main source for human infection is bite wounds from infected dogs. People and animals can be vaccinated both prophylactic and post-exposure prophylactic (PEP), despite this the disease continues to claim high number of victims. The majority of those dying are young men and children from the poorer part of the population. Knowledge among the Indian population on rabies and its transmission routes, wound care and vaccinations is very limited.

Trees in urban environment are exposed to extreme conditions, foremost the ones that grow in the hard packed soil along our streets. They are also exposed to damaging insects and fungal diseases both local and new ones spreading from South Europe. The global warming with warmer temperatures provides a longer growing season, making it easier for insects and fungus to establish a habitat. Based on these facts new tree species need to be available for future urban plantings.To determine what these trees would be an interview study began. Six people were selected who have experience in the field of urban environment planting.

Alien plants that have intentionally been introduced to an area for cultivation in public or private gardens constitute the primary pathway of introduction for invasive alien species that spread into nature. Garden owners want species that have satisfying characteristics, these characteristics are often also linked to plant invasiveness. Thus, the horticulture industry plays an important role by making scientifically based decisions and phasing out invasive plants and replacing them with alternative species with satisfying characteristics, but low risks of becoming invasive. This thesis aimed to examine the sale of and the attitudes towards alien plants in the horticulture industry in Sweden. Alien terrestrial plants identified to have a severe risk, high risk or potentially high risk of spreading and becoming invasive according to ArtDatabankens assessment, were examined to see if they were for sale.

This study had two different aims. The main aim was to investigate the dynamics and impact of African swine fever (ASF) on a farm in Uganda during a recent outbreak through a case study. The second aim was to estimate the presence of two important differential diagnoses of ASF: Classical swine fever (CSF) and Porcine Reproduction and Respiratory syndrome (PRRS).The field and laboratory based case study of the farm level dynamics of ASF virus during a recent outbreak (October-December 2010) on a farm in the district of Mityana, Uganda, was conducted, using interviews, ELISA and RT-PCR. The financial impact on the farm was also estimated. The impact of the outbreak was profound.

Syfte: Att undersöka hur patienter på ett universitetssjukhus uppfattar information gällande preoperativ dusch samt patientens genomförande av duschen på avdelningen. Introduktion: Vårdrelaterade infektioner är vanliga och kan leda till ökade kostnader, långvarig sjukhusvistelse och ökad lidande för patienter. Ett sätt att förhindra detta är att duscha med klorhexidin före operation. Det är sjuksköterskans ansvar att informera patienten om den preoperativa duschen, kontrollera att patienten uppfattat informationen och har möjlighet och resurser att följa den. Metod: En kvalitativ deskriptiv intervjustudie med semistrukturerade frågor.

African Swine Fever (ASF) is one of the most serious transboundary swine diseases because of its high lethality for pigs, socioeconomic consequences, rapid and international spread and the absence of either treatment or vaccine. This Sida Minor Field Study (MFS) was carried out during fall 2010, as part of a larger collaborative research project called ASFUganda, focusing on the epidemiology of the disease in Uganda. The aim with this study was to get more knowledge about the pathology in cases of ASF in Uganda, by studying macroscopic and microscopic lesions in pigs with acute and chronic ASF and to detect the ASF virus (ASFV) in tissues by immunohistochemistry. The pigs were selected from the two different geographical locations in Uganda, Mityana and Gulu district, both with on going confirmed outbreaks of ASF. Necropsies were performed in the field, and the laboratory procedures at the JICA (Japan International Cooperation Agency) Veterinary Pathology Laboratory, Entebbe, Uganda, and at the Department of BVF, SLU, Uppsala, Sweden. Three pigs from an outbreak of ASF in Mityana district showed both the history and the clinical symptoms typical for ASF.

This study is a degree project in environmental engineering at Mälardalens university. Its purpose has been to perform a risk assessment on whether or not any contaminations are present in the soil at two properties in Köping. The assessment was to be done accordingly to a method that has been set up by The Swedish Environmental Protection Agency (Naturvårdsverket). The method for investigation of contaminated sites is called MIFO. MIFO consists of two stages.

Medieföretaget AB is a Swedish Media Company that covers several different business areas.The company daily produces one of the biggest newspapers in Sweden and publishes editorialnews on one of the country?s most visited news homepage. The company also has smallerfirms that produce new business models. Due to big changes in the media climate over theworld and a new company management team the company in November 2008 started adepartment for innovation. The main purpose of the department was to create a structuredway for managing ideas and to promote innovation.

Scrapie is an infectious neurologic disease in sheep caused by prions, corresponding to transmissible spongiform encephalopathies (TSEs) in other species. The prion is presumably constituted of PrPSc, the misfolded form of the normal endogenous prion protein, PrPC, which is found in practically all cells in the body. PrPSc can induce a conformational change in PrPC and misfold it as an imprint of itself; this is how prions amplify and spread. The process of conformational change is poorly understood and there might exist intermediate forms between PrPC and PrPSc. Bioassay using mice has traditionally been the golden standard in prion studies but is limited by cost and time.

Title: ?We become like a little ambassador in the country of Facebook? ? an essay on the pres-ence of Swedish National Radio on Facebook. (?Vi blir som en liten ambassador I Facebooklan-det? ? En uppsats om Sveriges Radios närvaro på Facebook)Number of pages: 34 (46 including enclosures)Author: Nina WillénTutor: Christian ChristensenCourse: Media and Communication Studies CPeriod: Fall 2010University: Department of Informatics and Media, Uppsala UniversityPurpose/Aim: My purpose is to examine what the presence of the Swedish National Radio on a commercial network like Facebook means and how the editors themselves argue about it. For the analysis I use critical political economy as a theoretical point of view.Material/Method: The material consists of interviews made from a qualitative method.

Bakgrund: MRSA, metcillinresistenta staphyloococcus aureus, ökar idag i Sverige och i hela världen och bidrar till längre vårdtider, kostsamma behandlingar och mycket lidande för de drabbade patienterna och deras anhöriga. Syfte: Studien syftar till att undersöka hur patienter med MRSA upplever sin livssituation.Metod: Litteraturstudie  baserad på tio kvalitativa vetenskapliga artiklar.Resultat: Resultatet presenteras i tre teman benämnda ?Att vårdas?, ?Upplevelse av social förändring? och ?Att vara smittad med MRSA? med tillhörande subteman. Patienterna beskriver att bristfällig eller utebliven information om MRSA, dess symtom och effekter var ett problem. De beskriver också rädsla för att smitta sina närstående och vänner.

Höft- och knäprotesoperationer är idag en vanlig operation vid artros i höft- och knäled. Trotsminutiösa infektionsförebyggande förberedelser inför operationen drabbas ändå en delpatienter av postoperativa infektioner. Vid ortopedisk proteskirurgi är postoperativainfektioner ett direkt hot mot den nya inopererade leden och kan leda till långabehandlingstider som påverkar patientens livskvalitet under lång tid.Syftet med studien var att utforska patienters möjlighet till delaktighet i tidig upptäckt avpostoperativ infektion utifrån given information vid operation för höft- eller knäprotes.Semi-strukturerade intervjuer genomfördes med tio patienter med diagnostiserad postoperativinfektion efter höft- eller knäprotesoperation. Transkriberade intervjuer analyserades medinnehållsanalys. Journaler granskades för att beskriva patientens tidigare sjukdomar.Resultatet visade att första tecknen på infektion kan beskrivas med temat: Vad är normalt ochvad är inte normalt.

Uganda has the largest pig population in east Africa, and most of the animals are owned by smallholders. Infectious diseases among pigs have a devastating impact on the livelihood of these farmers, which are dependent on the proceeds from pig rearing. In a metagenomics study of the wild pig species bushpig (Potamochoerus larvatus), the porcine viruses Torque teno sus virus (TTSuV) 1and 2 and Porcine parvovirus 4 (PPV4) were detected. TTSuV1 and 2 are ubiquitous in the world?s swine population, and PPV4 has been found in USA and China, but neither of them has been studied in Africa previously.

Based on laboratory studies with lysimeters, the concentrations of dissolved reactive phosphorus(DRP) and particulate phosphorus, which is the main part of other P (OVRP), has been studied inpercolating water. The experiment was conducted through irrigation of small soil columnscontaining clay topsoil from an experimental field in Västergötland. Three rain simulations wereconsecutively performed. DRP concentrations in the percolating water ranged between 0.2 - 0.3mg·Lclearly related to the phosphorus concentration in the soil, measured in a soil extract ofammonium lactate (P-AL). Concentrations of OVRP were relatively low and ranged between0.12 and 0.16 mg·Lwas not proven and the experiment may reflect how a relatively slow percolation of water mayrelease DRP.