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11733 Uppsatser om Image-based screening assay - Sida 23 av 783
Neospora caninum hos köttdjur i Sverige :
Neospora caninum is an intracellular parasite that was first recognized in dogs in
1984. The parasite is now one of the most commonly diagnosed infectious causes
of abortion in cattle word wide. N. caninum is transmitted to cattle in two ways.
They may be infected from eating food contaminated with oocysts from a
definitive host or they may be infected in utero from an infected mother. The
infection is transmitted efficiently from cow to her offspring and this can occur
for generations.
Från frisk till sjuk på 4 minuter. Att få och leva med diagnosen abdominellt aortaaneurysm.
Bakgrund: Varje år dör cirka 1000 svenskar av brustet abdominellt aortaaneurysm (AAA), pulsåderbråck. Sjukdomen är ofta asymtomatisk och därför vet patienten i de flesta fall inte att hon eller han har en sjukdom förrän aneurysmet upptäcks. Sverige har på senare år infört screening på män över 65 år för att hitta eventuella AAA. AAA upptäcks även vid annan undersökning av buken. Mortaliteten är hög vid ruptur (bristning) och patienten opereras först när aneurysmet nått en viss diameter.
Why does trehalose not improve autophagy in the SOD1G93A transgenic mouse model of familial ALS?
Amyotrophic lateral sclerosis is one of the major neurodegenerative diseases, causing an ascending paralysis that usually kills the patient within a few years from disease onset. The motor neurons show aggregates of proteins which in approximately 20 % of cases of the familial form contain mutated SOD1 protein.
Trehalose is a disaccharide which has been shown to reduce protein aggregation and increase viability in cell models and alleviate symptoms in animal models of several neurodegenerative diseases associated with protein aggregation. When given orally to the SOD1G93A mouse model of ALS, trehalose failed to slow down the disease progression, which has led to questions about the uptake and distribution of the molecule in this mouse strain.
The aim of this study was to investigate whether significant levels of trehalose reach the central nervous system of the SOD1G93A mouse after oral administration. This was performed by a trehalose assay of the brain of trehalose treated animals. A glucose assay was optimised for use in small samples of brain lysate after the digestion of trehalose into glucose by trehalase, and the difference in glucose concentration before and after digestion represented the trehalose level.
Bältarbo tegelbruk och Sveriges tegelindustri under 1900-talet
This thesis is divided into two parts. Part one contains a general description of the flexographic printingtechnique. Part two contains a more detailed investigation in the areas substrate, inktransfer and trends, which are only briefly commented in part one, and conclusions and comments.The major problem concerning substrate is washboard. This phenomena can be limited if one can control and minimize the amount of glue applied in the single- and double facer, use high surface weight on liner, use low surfaceweight on fluting and control the humidity during the conditioning of the corrugated board. Corrugated board with a smooth surface radically increases the quality in print.
Shape from Silhouette Scanner
The availability of digital models of real 3D objects is becoming more and more important in many different applications (e-commerce, virtual visits etc). Very often the objects to be represented cannot be modeled by means of the classical 3D modeling tools because of the geometrical complexity or color texture. In these cases, devices for the automatic acquisition of the shape and the color of the objects (3D scanners or range scanners) have to be used. The scanner presented in this work, a Shape from silhouette scanner, is very cheap (it is based on the use of a simple digital camera and a turntable) and easy to use. While maintaining the camera on a tripod and the object on the turntable, the user acquires images with different rotation angles of the table.
Screening av nutritionsstatus hos kritiskt sjuka : en systematisk litteraturstudie
Syftet med denna studie var att kartlägga screeningsinstrument som mäter nutritionsstatus hos kritiskt sjuka samt se hur de används i vården. Studien genomfördes som en systematisk litteraturstudie. Artiklar söktes i databaserna Cinahl och Medline. Tretton artiklar identifierades, efter kvalitetsgranskning, till studien. I resultatet framkom flera nutritionsscreeningsinstrument och tre utav dessa; SGA, MUST och NRS 2002, var mer anpassade för screening av kritiskt sjuka.
Wermland Forever? : En underso?kning om hur Karlstads kommuns varuma?rkesidentitet avspeglas i Wermland Forever
Titel: Wermland Forever? En underso?kning om hur Karlstads kommuns varuma?rkesidentitet avspeglas i tv- serien Wermland ForeverSyfte: Syftet med uppsatsen a?r att belysa hur en stads image kan pa?verkas av en enskild marknadsfo?ringsa?tga?rd. I det ha?r fallet sponsring av tv-serien Wermland Forever som efterfo?ljdes av sa?va?l tittarstorm som la?ga tittarsiffror. Karlstads kommun mottog dessutom kritik fo?r sitt samarbete da? ma?nga ansa?g att tv-serien gick emot Karlstads kommuns va?rdegrund.Fra?gesta?llningar: Hur ser Karlstads kommuns varuma?rkesidentitet ut? Hur ser Karlstads kommuns varuma?rkesimage ut? Hur uppfattas bilden av Karlstad som visas upp i Wermland Forever? Hur ser fo?rha?llandet ut mellan Karlstads kommuns varuma?rkesidentitet kontra varuma?rkesimage ut i relation till Wermland Forever?Teori: Uppsatsen baseras till stor del pa? Simon Anholts fyra aspekter av ett varuma?rke samt Hart & Stachows ramverk fo?r att ma?ta Karlstads image.
Modellering av delvis kända objekt med hjälp av bilder
Today many different types of lock systems are used all over the world. Passwords, finger prints and magnetic strips are a few examples. When the key is a three dimensional object, lika a physical metal key, the security depends, in a high degree, on that you can?t copy the object without access to it. One approach to copying the object is photographing the object, and from these photographs create a copy.
Normering av Nordiskt Orofacialt Test- Screening (NOT-S) för barn 6:0- 8:0 år.
Andning, sväljning, tuggning, mimik och artikulation är delar av orofacial funktion (Bakke, Bergendal, McAllister, Sjogreen, & Asten, 2007). Oralmotoriken är viktig för talproduktion och födointag (Lundeborg Hammarström, 2010). Nordiskt Orofacialt Test- Screening (NOT-S) är ett screeningtest som används för att bedöma avvikande orofacial funktion (Bakke et al., 2007). Syftet med studien är att undersöka hur barn med typisk utveckling mellan 6:0- 8:0 år presterar på NOT-S, samt om det föreligger någon ålder- eller könsskillnad i utförandet av uppgifterna. I studien deltog 80 barn och deras föräldrar.
SMÅORTSHOTELL - En undersökning om imageskapande.
Problem: Småortshotell har andra förutsättningar än storstadshotell för att kunna överleva. Det gäller både distansen till samt utbudsnivån i hotellen. Den geografiska placeringen gör att resenärer inte passerar dem utan gästerna kommer till småortshotellen för att uppleva deras utbud. Syfte: Vårt syfte är att undersöka hur småortshotell strategiskt arbetar med imageskapande ur marknadsföringsperspektiv. Frågeställningar: Vilken image vill småortshotellen förmedla?Vilka samarbetsformer har småortshotellen?Vilka underliggande betydelser förmedlar småortshotellen? Metod: Vi har använt oss av kvalitativa metoder som består av två delar, datainsamlingsmetoder och semiotikdokumentanalys.
Flexorafiskt tryck på wellpapp
This thesis is divided into two parts. Part one contains a general description of the flexographic printingtechnique. Part two contains a more detailed investigation in the areas substrate, inktransfer and trends, which are only briefly commented in part one, and conclusions and comments.The major problem concerning substrate is washboard. This phenomena can be limited if one can control and minimize the amount of glue applied in the single- and double facer, use high surface weight on liner, use low surfaceweight on fluting and control the humidity during the conditioning of the corrugated board. Corrugated board with a smooth surface radically increases the quality in print.
Med kulturen som redskap : En fallstudie om kulturell representation och dess möjligheter att stärka Sverigebilden utomlands
AbstractIn the heart of Paris, you will find Sweden?s only cultural center abroad. Since the early 70?s a wealth of cultural activities has been offered, and every year the center receives more than 100,000 visitors. The center is a branch of the Swedish Institute (Si), a public authority which promotes mutual relationships between Sweden and other countries through culture, education, science and business.
En berg- och dalbana av genusstrategier : En studie om den normativa genusbildens konsekvenser för kvinnor med erfarenhet av narkotikamissbruk.
A qualitative interview study how the normative gender images affects on women, their roles and positions in a drug abuse. The purpose of this study aims to shed a light at the consequences that the normative gender scenario inflicts on women with drug abuse and how these prejudices affects these women. Based on interviews with four different women who all lived with a drug abuse we have problematized how the gender system and the normative gender images affected them. We have used gender perspectives and social constructivism theories while analyzing the empirical basis. More specifically we use the theories of Butler about how gender constructs through performative actions and Hirdmans theories of the gender system.
A targeted evaluation of OpenEye?s methods for virtual ligand screens and docking
The process of drug discovery is very slow and expensive. There is a need for reliable in silico methods; however the performance of these methods differs.This work presents a targeted study on how the drug discovery methods used in OpenEye?s tools ROCS, EON and FRED perform on targets with small ligands. It was examined if 12 compounds (markers) somewhat similar to AMP could be detected by ROCS in a random data set comprised of 1000 compounds. It was also examined if EON could find any electrostatic similarities between the queries and the markers.
Varumärkesbyggande inom småföretag: en fallstudie om hur småföretag skapar värde genom sitt företagsnamn
This thesis intended to examine how small enterprises within the retail industry work with brand building of their corporate name. More specifically it intended to examine how they do to choose corporate name and corporate logotype, and how they work to create a desired corporate image. A case-study was performed with three case-companies from different industries. The method was deductive as the empirics were brought in with starting-point in the theoretical frame of reference. The study showed that there are differences in the way small enterprises within the retail industry work with the brand-building of their corporate name.