Mast cells have for a long time been known to accumulate around tumors (Maltby et al., 2009). Studies show that they may be important and sometimes essential in tumor angiogenesis, tumor growth and metastasis of tumors (Soucek, et al., 2007; Xiang et al., 2010). In an expression array study (Wensman et al, submitted manuscript) performed on mouse mast cells exposed to tumor conditioned medium, the gene 4-1BB was among the most up-regulated genes compared to control medium. 4-1BB codes for a membrane receptor protein of the tumor necrosis factor superfamily and has been shown to be important in T cell regulation in tumor diseases. This study was performed to investigate if human mast cells up-regulate 4-1BB when they get exposed to tumor conditioned medium.

The purpose of this essay is to examine Swedish HR-managers who have either received, or been nominated for, the award ?HR-manager of the Year?. We investigate the managers? personalities, how they think about their own role and HR?s function in the organization, all in an environment that can be characterized by some skepticism towards HR. We find the HR-managers to be ?winners?; strong individuals that are confident, communicative, and driven.

Motivationsskapande åtgärder är avgörande för de anställdas nöjdhet inom organisationen. Vad som motiverar de anställda varierar från individ till individ. Vårt resultat visar att det existerar ett samband mellan de anställdas nöjdhet och hur väl organisationens strategi, struktur, utvärderingar och belöningar stämmer överens med olika karriärinriktningar och drivkrafter. Studien visar även att de anställdas nöjdhet påverkar kundernas nöjdhet med servicen..

Today's technology offers a variety of opportunities to interact with the interactive systems. Human-Computer Interaction in the last decade is the area of research that has contributed the most to this development. But how is this interaction perceived? The user experience is something that is formed by the interaction between human and the computer interactive systems. The objective of this thesis is to investigate how the user experience differs depending on how one interacts with a game.

Identity includes an individual´s self-image and the consciousness about their self. It is about being the same person despite changes in their life situation. The identity often get´s fragile because of the disease. Beacuse of the individual´s feeling of lost identity there may arise a conflict between the person and people in his or her surroundings. They may no longer see the sick person in the same way as they used to.

Most studies regarding wolf (Canis lupus) predation on moose (Alces alces) have focused on the total annual consumption of moose within a wolf territory but few have tried to describe the spatial impact of wolf predation on a local scale. In this study I have analyzed wolf movement data, wolf predation, moose hunting statistics and moose hunter observations to investigate how wolf predation affects the human harvest of moose in Scandinavia. Since wolves prey on mostly juvenile moose during summer, analysis of their summer movement patterns is crucial to understand its impact on the human harvest later during autumn. In this study both reproducing (n = 45) and non-reproducing wolves (n = 12) reduced their movement range during summer to 66% and 67% of their annual movement range, respectively. Reproducing wolves increased their movement range from early to late summer while non reproducing wolves did not.

Small business enterprises have escalated in Sweden during the last decade. However, new established companies are struggling to maintain their selves during the startup process and according to a survey from Tillväxtanalys, only 68 % of startup companies from 2008 were still active three years later. One of the main reasons is lack of capital and the most common approach to finance companies is to apply for a bank loan. In other words, commercial banks are of great importance for new businesses. Although, the problem arises when there is no previous history from the new businesses that the bank could base its credit assessment on.

The purpose of this thesis is to examine if the school's democracy project is successful. The objective is examined in relation to two specific questions. The first question is whether students, after completing their studies in civics A, understand the relationship between the concepts of human rights and democracy. The second is if the students understood the concepts of practical significance and impact on society and the individual. Variation theory comes from the phenomenographic theories and is central to this work. The approach to learning, in this essay, is a change in how a person experiences, understands or perceives a phenomenon. Variation theory focuses on a learning object and contextualization sees as crucial to how the individual perceives the object.The study is based on a quantitative research method in the form of a survey at a secondary school. A number of students may respond to valuation questions about how they perceive democracy and human rights in practical situations. The results are related to curriculum goals.The results of the study is not positive in relation to curriculum objectives, where many students respond negatively to questions..

The Swedish industrial society has left several areas with contaminated soil and water which today is of danger for the environment and human health. One of these areas with contaminated soil and water is the region where the former Glava glassworks operated during 1859 to 1939. The main object in this study has been to study the responsibility for the contaminations according to the Environmental Code. The method used is a qualitative content analysis of relevant literature to answer the following questions:What types of contaminations can be found in the area of Glava glasswork and what health issues can these cause?What kind of activity has been conducted in the area that have caused the contaminations in soil and water?According to law, what are the responsibilities for the contaminations in soil and water at Glava glassworks?The contamination in the region has been confirmed to originate from the glasswork due to the environmental engineering survey made in the area in 2009.

This study focuses on the development of methods for sexual determination of human skeletal remains, mainly between the years 1981 to 2007. By comparing an older analysis from 1983 (Persson and Persson) with my own on the same material, a difference of 40% was shown, which indicates that the methods has changed through time, and that these should not be used for newer conclusions about a population if the method is not throughoutly described.The main cause of the difference was identified as a change in the reliability of the sexual indicators, rather than a total change of method. Any general tendencies did not show, it is however considered that the pelvic bones are able to make a better conformity between the analyses as opposed to using the cranium..

Background: As Porter?s diamond (1990) suggested, the business environment highly influences firms? strategies. Today, most of the companies have to decide their strategy depending from a worldwide business environment. Yet, strategy researches and the growing importance of marketing for business success also show that customer dimension must be taken into consideration. On some markets and in certain industries, the offer is much higher than the demand and then, companies need to attract customers.

This paper discusses an osteological- and archeological analysis of a cairn from the Bronze Age on Gotland. The osteological material consists of both burnt and and unburnt bones from both human and animal. The objective of this paper is to shed light on the individuals who were buried in the cairn. It is also to generate information about continuity in its use and patterns of distribution of the bones and grave-goods in the cairn. The osteological analysis show that a minimum of five human individuals is present in the osteological material.

Syftet med detta arbete är att studera finansialiseringens spridning och kopplingen mellan processer och strukturer inom finansialiserings-teori och Human Resource Management (HRM). Detta genom att studera en organisation och dess HR-praktik i jämförelse med ovan nämnda teorier. De två teoretiska perspektiven används för att illustrera vilka konsekvenser som kan tydliggöras för arbetstagare och organisation. I studien undersöks en HR-verksamhet på den svenska arbetsmarknaden där det empiriska materialet består av kvalitativa intervjuer med representanter från organisationens HR-funktioner. Studien har ett abduktivt förhållningssätt där underlaget bygger på en teoretisk förförståelse samtidigt som en lägre grad av standardisering i intervjuerna används för att låta det studerade fältet styra den empiriska bilden.

The main aim of this study is to examine the political debate in Sweden around a potentionalcriminalization of buying sex abroad. A second additional aim is to analyze the debate from anintersectional feminist gender perspective, by bringing attention to ideas about gender, ethnicity andpower expressed in the empirical material.The questions at issue are:What are the arguments for and against the potentional criminalization of buying sex abroad andwhich central discursive battles can be discerned throughout the debate?What impact do ideas about gender and power have on the construction of a general advocatediscourse versus a general antagonist discourse?The methodological point of departure is Critical Discourse Analysis, drawing on the theories ofNorman Fairclough, Ernesto Laclau and Chantal Mouffe. The empirical material consists of 27articles and editorials publicized in Swedish newspapers between January 2011 and November2014.The result shows that the polemics manifested in the debate are based on different ideas aboutgender, ethnicity and power. A crucial discursive battle stands between human rights andinternational law as a superior principle.

En av barnmorskans uppgifter under förlossningen är att ge kvinnan stöd. Det finns lite forskat kring vad som ärstärkande för en kvinna i samband med förlossning. Syftet med studien var att undersöka vad kvinnor upplevdesom stärkande under normal förlossning. Fyra kvinnor intervjuades och de transkriberade intervjuernaanalyserades genom innehållsanalys med en induktiv ansats. Resultatet består av fyra kategorier: tillit till sigsjälv och sin kropp, förberedelse, stöd från partnern, och stöd från barnmorskan.