Mast cells have for a long time been known to accumulate around tumors (Maltby et al., 2009). Studies show that they may be important and sometimes essential in tumor angiogenesis, tumor growth and metastasis of tumors (Soucek, et al., 2007; Xiang et al., 2010). In an expression array study (Wensman et al, submitted manuscript) performed on mouse mast cells exposed to tumor conditioned medium, the gene 4-1BB was among the most up-regulated genes compared to control medium. 4-1BB codes for a membrane receptor protein of the tumor necrosis factor superfamily and has been shown to be important in T cell regulation in tumor diseases. This study was performed to investigate if human mast cells up-regulate 4-1BB when they get exposed to tumor conditioned medium.

The earmould acoustics affect the amplification that the hearing aid is programmed to give to its user. It is therefore important that the choices made for the earmould are correctly done. One choice is regarding the shape of the soundbore that affects the frequency response of the hearing aid above a certain cut-off frequency. The purpose of this project was to measure the frequency response when altering the shape of the soundbore in the earmould. Additionally, the aim was to examine how the frequency response is affected when the shape of the soundbore is not set or is not possible to set in the software when programming the hearing aid.

What if the emergency response directly knew exactly where to go and what to do if a road accident occured? During the last ten years the number of motorcyclists in Sweden has doubled. Every year, more than 300 riders are seriously injured and over 40 die in road accidents. Being found in time is critical to increase the chance of survival. The goal of this project is to use design methods to find a solution that enables a fast and adequate emergency response for motorcyclists and other unprotected road users..

ObjectiveThe objective of this study was to investigate differences between monotich and dichotic 40 Hz Auditory Steady-State Response (ASSR) with Interacoustics Eclipse.DesignThe aspects studied are test duration, relation be¬tween ASSR and behavioural thresholds (BT), reproducibility and correlation between rejects during Brainstem Response Audiometry (BRA) and differences between ASSR and BT. Monotic and dichotic ASSR-thresholds for eight normal hearing subjects (.

Purpose: The purpose of this thesis is to study the causal relationship between bank sector development and economic growth in four Nordic countries (Sweden, Finland, Denmark and Norway).Method: Our thesis is based on a quantitative method. The study consists of a compilation and analysis of key financial indicators that represent economic growth and bank sector development. A Granger causality test has been conducted on the time series in order to measure the causal link between economic growth and bank sector development.Theoretical framework: The study is based on the theory of endogenous growth and the causal relationship between bank sector development and economic growth also known as the demand following and supply leading hypothesis. Results: The results of the four countries are ambiguous. Except for Denmark, that follows the supply leading hypothesis, the remaining countries do not show a unanimous result..

The effect of methyl jasmonate on resistance against the large pine weevil (Hylobius abietis) in Scots pine and Norway spruce seedlings. A field experiment was conducted in order to determine the dose-response effects of methyl jasmonate (MJ) on growth and defence to pine weevils in Scots pine (Pinus sylvestris) and Norway spruce (Picea abies) and to compare the effect of MJ between pine and spruce. In addition a complementary greenhouse experiment was conducted with the same aims as above and to determine the amount of resin ducts and their correlation to the feeding of pine weevils. The field experiment was conducted on a fresh clear cutting in Garpenberg, southern Dalarna in central Sweden. The experiment consisted of 30 blocks with three kinds of containerized seedlings: 2-year old spruce, small pine (before shoot elongation) and 1-year old pine (already shoot elongated). They were all exposed to 4 treatments 14 days prior to the experiment: control, 25 mM/L MJ, 50 mM/L MJ and 100 mM/L MJ. Data on weevil damage and seedling growth were collected after the first and the second growing season. The seedlings in the greenhouse experiment were of the same kind and were exposed to the same treatment as the ones in the field experiment.

The aim ofthis study was to examine how economic growth affects the level of democracy inauthoritarian states. Some of these states have experienced high economicgrowth. However, one can discuss how it affects the country?s democratization-process.For that reason this study was needed to contribute to a clarification of howeconomic growth can affect authoritarian rule and democratization. This wasdone through an examination of the development in China.

The structures of organizations have gone through a dramatic change over the last years; as a result customer service is no longer a small side activity but a critical part in customer relationship management. Development in information technology has created opportunities as well as challenges for organizations when it comes to providing a customer service with capacity of sensing and responding to customers' needs. Previous research shows a relationship between customer response capability and customer knowledge processeses, this study investigates and confirms this relationship. However, findings show that dedication and understanding for customers needs has a direct impact on both customer response capability and customer knowledge processeses, this result indicates that customer knowledge processes and customer relationship management are difficult to differentiate. Furthermore, this study explores IT-related resources impact on customer response capability and customer knowledge processes.

Recent years there has been discussed how the critical situation in the housing market threatens the Stockholm region's growth. The thesis objective is to examine whether there is a scientific link between the lack of housing supply and growth. The thesis also intends to identify solutions for increased housing construction, for instance by examining the conditions for a greater regional perspective and influence on the region's housing supply. The thesis empirical study is based on semi-structured interviews with representatives from the Government, municipalities and the housing industry.In Sweden, research on the relationship between housing shortages and growth has not been conducted to that extent it can be said to exist scientific evidence regarding the growth threat. However, in Britain and the U.S, empirical studies show that a lack of housing supply has hindered growth through negative impact on countries' gross domestic product.

Recent years there has been discussed how the critical situation in the housing market threatens the Stockholm region's growth. The thesis objective is to examine whether there is a scientific link between the lack of housing supply and growth. The thesis also intends to identify solutions for increased housing construction, for instance by examining the conditions for a greater regional perspective and influence on the region's housing supply. The thesis empirical study is based on semi-structured interviews with representatives from the Government, municipalities and the housing industry.In Sweden, research on the relationship between housing shortages and growth has not been conducted to that extent it can be said to exist scientific evidence regarding the growth threat. However, in Britain and the U.S, empirical studies show that a lack of housing supply has hindered growth through negative impact on countries' gross domestic product.

As well as other politic fields, the cultural politics adapt to changes in society. The development in society has brought attention to the interaction between the cultural field and the economic field. One of the main goals within Swedish Cultural Policies today is the development of cultural and creative economics. Politicians and researchers claim that culture can be a significant part in economic growth in cities and making a place attractive to live in.I became interested in the discussion around the cultural experience as a factor of economic growth when I participated in a seminar at Karlstad CCC during Kulturparlamentet 2012. When I then started working at the music festival Putte i Parken during the spring of 2013 I thought about making this study.The main aim is to investigate in which way Putte i Parken can be a factor of growth and a factor of making Karlstad an attractive place to live in by analyzing documents, reports and literature in a qualitative way of working.

The purpose of this study is to make a close and critical scrutiny of the EU Lisbon Strategy and the assumption of `sustainable growth´. A basic question is to clarify what is meant by `sustainability´ in the economic and the environmental dimension respectively, and also, to analyse the meaning of `sustainable growth´. Secondly, I try to investigate the relationship between the economical and environmental dimensions of the strategy. Are the goals of the dimensions compatible and mutually supporting or are they conflicting? By illuminating these issues the study moves towards a final set of questions: What are the arguments that encourage or counteract the Lisbon assumption of `sustainable growth´? Is the European Union approaching `sustainable growth´ looking at different economical and ecological indicators? What are the prospects for the Lisbon Strategy as a way towards global `sustainable development´?.

Development of morphs within European whitefish (Coregonus lavaretus), might be considered as a beginning of a sympatric speciation process. Unpublished data suggests that presence of the keystone piscivore northern pike (Esox lucius) is the main driver of sympatric divergence in European whitefish (Coregonus lavaretus). Using introduced whitefish populations as controlled experiments, it is possible to determine when different characters diverge in the speciation process. In this study, I analysed age and growth within European whitefish populations of different age to assess if these characters change over time in absence of pike. With using otoliths from whitefish populations of different age, I was possible to determine individual age, and by measuring the length of the fish, growth was calculated.

Many sources point to the same conclusion; throughout the history the research sphere, mass media, governmental industry policies and public life in common have not paid the same attention to medium-sized companies as to small, new or large companies in Sweden. Yet, there are some researchers claiming the need for the medium-sized companies to grow, becoming tomorrow?s Swedish new large companies. Hence, the need for understanding the specific growth conditions of the medium-sized companies are definitely clear. This study aims firstly to identify whether there are specific requirements and obstacles for growth in connection to being a medium-sized company.

ObjectiveThe objective of this study was to investigate the clinical application to use ASSR in anesthetized childrenDesignOne main ambition of the investigation was to compare hearing threshold using ABR with estimated hearing threshold using ASSR. Another aim was to examine if the duration of an ASSR measurement could be reduced by only using the frequencies 1, 2 and 4 kHz and exclude the frequency 0.5 kHz. This is a retrospective study using electrophysiological measurement from a database.ResultResults showed a high correlation between hearing threshold using ABR and estimated thresholds using ASSR, with the frequency 0.5 kHz showing a slightly lower correlation. Result also showed that the test duration was increased when using all test frequencies in ASSR-measurement compared to when 0.5kHz was excluded. ConclusionThe study showed a high correlation when comparing hearing threshold using ABR and ASSR.