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314 Uppsatser om Genetic ontology - Sida 2 av 21

Privatiseringen av de växtgenetiska allmänningarna : Konsekvenserna av regimkomplexet kring växtgenetiska resurser för bönders rättigheter och matsäkerhet

This thesis discusses the global regime complex concerning the management of plant genetic resources for food and agriculture, and how different regimes concerning these resources cooperate or stand in opposition to each other. Because of changes in US patent law and the establishment of TRIPS, patent claims over plant genetic resources has increased dramatically globally. This, amongst other things, in turn has lead to the development of CBD which in turn lead to the creation of access and benefit laws in many countries. To create a free flow of genetic resources for food and agriculture the ITPGRFA, with its multilateral system, were negotiated. The aim of this thesis is to investigate which consequences the regime complex concerning plant genetic resources for food and agriculture can have on the rights of small farmers, agricultural research and food security in the global South.

Bevarande av de svenska lantraserna, populationsgenetiska och molekylärgenetiska metoder

Today?s community requires an increase in food production. Animals are today bred so that they produce more than their ancestors did. Production has been the most important and breeds with the highest production levels have therefore become popular. Many of the old local breeds have become extinct or are about to become extinct because of this trend.

Felaktig alternativ splicing: Vissa mutationer i BRCA1, BRCA2, ER? och ER? är starkt förknippade med bröstcancer

Alternative splicing is a process that partly rejects the common definition of a gene ? that one gene codes for one specific protein. By variable combination of coding regions (exons) and exclusion of non-coding regions (introns), formation of several different mRNA-transcripts, and consequently several different proteins, can derive from the same gene. Alternative splicing is an important condition for the development of complex life forms, but it is also a highly sensitive process and inaccurate splicing is the cause of approximately 15 % of mutations that cause genetic diseases. This article presents four genes, BRCA1, BRCA2, ER? and ER?, and inaccurate splicing of these genes increases the risk of developing cancer, particularly breast cancer and ovarian cancer.

Mätegenskaper för fruktsamhet och modersegenskaper i fåraveln :

The aim of this literature review was to suggest suitable index traits to use in the Swedish Sheep Recording Scheme for fertility and maternal traits. Since fertility and some of the maternal traits are not normally distributed advanced methodology is needed to calculate genetic parameters. Breeding is a tool to improve the economy of the farm and for the selection of breeders estimated breeding values (EBV) for important traits are of high value. In sheep breeding both lambs born and lambs weaned should be taken into consideration as well as the ewe?s maternal ability, which includes lambing ease, lamb survival, ewe behaviour as mother and the early growth of the lambs.

Näthinnesjukdomar hos hund :

An array of different retinal disorders is present as a threat in quite a number of dog breeds. These often lead to profound visual impairment or blindness. Many of the disorders are genetic, and they are, in Sweden as well as in other countries, subject to breeding programmes. The anatomy of the eye and the retina, as well as current examination techniques (ophthalmoscopy, electroretinography (ERG) and genetic analysis) are described. The more common retinal disorders encountered in dogs in Sweden are discussed: retinal dysplasia, generalized progressive retinal dystrophy, retinal pigment epithelial dystrophy, collie eye anomaly, sudden acquired retinal degeneration, retinal detachment and choroiditis. The possibly affected breeds are listed. The value of diagnostic findings is discussed and current advances on the subject in ophthalmologic research are accounted for..

Idiopatisk epilepsi hos hund

ABSTRACT Epilepsy describes a neurologically caused condition which involves seizures. Epilepsy can be classified according to different types of causes and the nature of seizures can vary. Medication for epilepsy in dogs is limited in comparison with human medicine. Idiopathic epilepsy is the most common neurological disease and one of the most common genetic diseases in dogs. Because epilepsy has a higher prevalence in certain breeds, there is reason to suspect that it is a hereditary disease. The inheritance of idiopathic epilepsy is for most breeds not determined, except for a few variants of the disease.

Genomisk selektion inom köttraser

Genomic selection (GS) is used for selection of breeding animals of dairy cattle. GS is though not as extensively used within the beef industry. One reason for that is the low accuracy (rTI) of the breeding value that is of great importance for the final genetic gain. Causes to the low accuracy are high effective population size, a small reference population and a genetically differentiated population. There is however a market for genomic selection with High Density (HD) tests for beef cattle.

Självmord : en forskningsöversikt

Suicide is the ultimate outcome of mental illness and is a big and serious problem in society. About 1500 persons commit every year suicide in Sweden and many more engage in suicidal behaviour. This review aims at, from research studies from the 21th century, find out the knowledge of riskfactors regarding the risk for committing suicide among adolescents. The research questions are: What does research say, from a psychobiological perspective, about riskfactors among adolescents regarding the risk for suicidal behaviour? How much does genetic factors have an effect on the risk for suicidal behaviour among adolescents? and : What is the importance of environmental factors such as family connections, friends and school environment concerning suicidal thoughts among adolescents?The method that is used in order to answer these questions is a researchreview including ten research-studies.

Phenotyping of Bali cattle and interviewing farmers in Indonesia - a minor field study

Among the Indigenous cattle breeds in Indonesia, the Bali cattle is the most preferred by small farmers. The Bali cattle is a beef breed, and is considered to have several advantageous characteristics and to be well adapted to the country?s harsh environmental tropical conditions with drought and rain. The main aim of this project was to phenotype of Bali cattle from different locations in order to identify and document diversity within the Bali cattle breed based on their observable characteristics, to compare cattle from different areas and production systems to see the effect of management on phenotype. In this study, 107 cows and bulls of the breed Bali cattle, from Kalimantan, Sumatra, Lombok and Bali were phenotyped.

Genetisk variation i brunststyrka hos svenska mjölkkor :

When cows in Sweden are inseminated the heat strength is reported to the Swedish milk-recording scheme and AI scheme. Cows that show strong signs of estrus are desirable and the trait is included in the Swedish breeding goal. A strong heat makes it easier to inseminate at the right time and to avoid long and expensive days open. Since ten years the heat strength is scored from one to five by the farmer and reported to the milk-recording scheme and AI scheme. Earlier the score was from one to three and the decision was made by the AI technician.

Centrum för lättläst : Ur ett domänanalytiskt perspektiv

The aim of this two years master thesis in Library and information science is to study the foundation Centrum för lättläst and its work regarding information use with focus on information structures and information needs. The aim is also to examine how Centrum för lättläst cooperate with Swedish libraries to promote the work concerning people with reading disabilities. This master thesis applies a domain analytic theory and method inspired by Birger Hjørland. The domain analysis is confined to examine ontology, epistemology, sociology, empirical user studies, document and genre studies and studies of structures and institutions in scientific communication. The main source material consists of information from the homepage of Centrum för lättläst.

Genomisk selektion och uppbyggnaden av avelsprogram hos mjölkkor

During the last decade a new technique in animal breeding has developed called genomic selection. It is based on estimations of the effect from genetic markers on traits that are calculated in a reference population. By genotyping individuals, genomic breeding values can then be estimated without phenotypic observations. The aim of this essay is to investigate the response of genomic selection on breeding schemes for dairy cattle. The accuracy of the genomic breeding values is affected by the proportion of observations included in the validation set and how often the equation for estimating breeding values is reevaluated.

SAMMANS?TTNING AV MAKROALGER I SVENSKA ?LGR?S?NGAR eDNA sp?rning och klimatf?r?ndringar

The aim of my bachelor?s thesis is to investigate, through a literature review, changes in the distribution of filamentous algae as well as the general species composition of macroalgae and diatoms in Swedish eelgrass meadows. I have also studied the possibility of tracking these algae and diatoms in eelgrass meadows using eDNA methodology. The focus has been on linking these changes to climate change factors such as eutrophication, temperature increase, and anthropogenic emissions, and how these affect the health of eelgrass meadows and their ecosystem services, such as a carbon sink and biodiversity support. The results show that filamentous algae have increased markedly in coverage in Swedish coastal areas between 1980 and 2021, especially in sheltered bays, indicating that altered environmental conditions favor these fast-growing species. Genetic tracking using eDNA demonstrated that there are functional primers for many species, particularly among brown algae and red algae, whereas green algae require more specific primers due to greater genetic variation.

Genetisk analys av data från fölbesiktning och jämförelse med resultat vid treårstest :

More than 1000 Swedish Warmblood foals are shown every year at foal inspections which are arranged around the country. Six traits are evaluated at these inspections: type, head-neck-body, correctness of legs, walk, trot and canter. No previous genetic studies have been done on the data from these evaluations. The purpose of this study was to do genetic analyses of the traits which are evaluated at foal inspections. The purpose was also to see if there are any correlations between the results of the foal inspections and the results from the tests of three-year-old horses.

Kalvningsintervall hos svenska köttkor : finns det genetisk variation som kan användas i avelsarbetet?

The Swedish beef cattle population is growing when the dairy cattle become fewer. The fertility of the beef cows is important for the profitability in beef cattle production. Today there is no genetic evaluation for female fertility in Swedish beef cows. The purpose of this study was to see if calving interval can be used in the genetic evaluation as a measure of female fertility in beef cows. For this purpose the variation in calving interval for beef cows of different breeds and ages registred in KAP was studied.

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