Alternative splicing is a process that partly rejects the common definition of a gene ? that one gene codes for one specific protein. By variable combination of coding regions (exons) and exclusion of non-coding regions (introns), formation of several different mRNA-transcripts, and consequently several different proteins, can derive from the same gene. Alternative splicing is an important condition for the development of complex life forms, but it is also a highly sensitive process and inaccurate splicing is the cause of approximately 15 % of mutations that cause genetic diseases. This article presents four genes, BRCA1, BRCA2, ER? and ER?, and inaccurate splicing of these genes increases the risk of developing cancer, particularly breast cancer and ovarian cancer.

The aim of this literature review was to suggest suitable index traits to use in the Swedish Sheep Recording Scheme for fertility and maternal traits. Since fertility and some of the maternal traits are not normally distributed advanced methodology is needed to calculate genetic parameters. Breeding is a tool to improve the economy of the farm and for the selection of breeders estimated breeding values (EBV) for important traits are of high value. In sheep breeding both lambs born and lambs weaned should be taken into consideration as well as the ewe?s maternal ability, which includes lambing ease, lamb survival, ewe behaviour as mother and the early growth of the lambs.

Inbreeding has become a problem in some horse breeds. Studies show that it may lead to inbreeding depression which affects e.g. reproduction traits. In the wild there are mechanisms that make horses avoid mating with close relatives. When selection is done by humans this mechanism is removed and intensive breeding for a few traits, for example good racing results, can become a problem.

The goal of this Master thesis has on the one hand been to create a simulation environment for robots, where not only the simulations in this work can be performed, but also similar robot simulations, and on the other hand to study regulators that can increase the possibilities of rejecting disturbances on an industrial robot. The robot model used has three degrees of freedom, corresponding to the three main links on ABB:s IRB7600. The simulation environment is created using Matlab, Simulink, and Robotics Toolbox. It is constructed in a general way and can be used for simulations of other robot objects created in Robotics Toolbox. A gain scheduling is added to the LQ-regulator, where the feedback matrix is varied depending on the arm position in the workspace.

An array of different retinal disorders is present as a threat in quite a number of dog breeds. These often lead to profound visual impairment or blindness. Many of the disorders are genetic, and they are, in Sweden as well as in other countries, subject to breeding programmes. The anatomy of the eye and the retina, as well as current examination techniques (ophthalmoscopy, electroretinography (ERG) and genetic analysis) are described. The more common retinal disorders encountered in dogs in Sweden are discussed: retinal dysplasia, generalized progressive retinal dystrophy, retinal pigment epithelial dystrophy, collie eye anomaly, sudden acquired retinal degeneration, retinal detachment and choroiditis. The possibly affected breeds are listed. The value of diagnostic findings is discussed and current advances on the subject in ophthalmologic research are accounted for..

ABSTRACT. In the late 1960?s all the wolves in Scandinavia went extinct in the wild due to extensive hunting. In 1983 two new wolves immigrated and founded, together with a third immigrant in 1991, the population that exists today. Due to the fact that the population originates from less than a handful of individuals, the genetic variation is small.

ABSTRACT Epilepsy describes a neurologically caused condition which involves seizures. Epilepsy can be classified according to different types of causes and the nature of seizures can vary. Medication for epilepsy in dogs is limited in comparison with human medicine. Idiopathic epilepsy is the most common neurological disease and one of the most common genetic diseases in dogs. Because epilepsy has a higher prevalence in certain breeds, there is reason to suspect that it is a hereditary disease. The inheritance of idiopathic epilepsy is for most breeds not determined, except for a few variants of the disease.

Sitka spruce (Picea sitchensis) is not considered to be a native species to Swedish forests. It´s origin is the pacific coast of Northern America, an area that is dominated by a coastal climate which makes it likely to believe that it would be well suited for growing in the south-west of Sweden. This study aims to investigate the gain in production that can be reached by growing sitka spruce instead of Norway spruce (Picea abies) in the county of Halland. A regression model based on data from forest experiments was produced to explain the gain in production. This model was based on elevation and annual precipitation. The model was then used to create a map layer in arcGIS that shows the gain of volume in comparison to Norway spruce in percent. An analysis was carried out to find what share of the forestland in Halland county that fell into four different classes of production gain.

Suicide is the ultimate outcome of mental illness and is a big and serious problem in society. About 1500 persons commit every year suicide in Sweden and many more engage in suicidal behaviour. This review aims at, from research studies from the 21th century, find out the knowledge of riskfactors regarding the risk for committing suicide among adolescents. The research questions are: What does research say, from a psychobiological perspective, about riskfactors among adolescents regarding the risk for suicidal behaviour? How much does genetic factors have an effect on the risk for suicidal behaviour among adolescents? and : What is the importance of environmental factors such as family connections, friends and school environment concerning suicidal thoughts among adolescents?The method that is used in order to answer these questions is a researchreview including ten research-studies.

Among the Indigenous cattle breeds in Indonesia, the Bali cattle is the most preferred by small farmers. The Bali cattle is a beef breed, and is considered to have several advantageous characteristics and to be well adapted to the country?s harsh environmental tropical conditions with drought and rain. The main aim of this project was to phenotype of Bali cattle from different locations in order to identify and document diversity within the Bali cattle breed based on their observable characteristics, to compare cattle from different areas and production systems to see the effect of management on phenotype. In this study, 107 cows and bulls of the breed Bali cattle, from Kalimantan, Sumatra, Lombok and Bali were phenotyped.

When cows in Sweden are inseminated the heat strength is reported to the Swedish milk-recording scheme and AI scheme. Cows that show strong signs of estrus are desirable and the trait is included in the Swedish breeding goal. A strong heat makes it easier to inseminate at the right time and to avoid long and expensive days open. Since ten years the heat strength is scored from one to five by the farmer and reported to the milk-recording scheme and AI scheme. Earlier the score was from one to three and the decision was made by the AI technician.

This paper examines how the ideal of manhood is portrayed and constructed and how the participation of Swedish soldier volunteers are motivated and legitimatized. The purpose of this examination is to gain understanding and knowledge about the Swedish soldiers in the Swedish brigade, how they legitimatize and motivate their participation and how the ideal of manhood is portrayed and constructed. The study is based on material from the war archive in Stockholm. The empirical material is composed by letters and propaganda material. In the analysis of the empirical study, there have been two theories used which are Eric Hobsbawms historical method and theory about invented traditions and Peter Aronssons historical method and theory about ?historiebruk? and legitimacy.

The purpose of this masters thesis is to evaluate the retrieval effectiveness of three different search engines on the Internet: Google, Yahoo! and MSN Search. We have constructed 25 topics and queries with varying contents, in order to test the width of the search engines as much as possible. In every search we have evaluated the first 20 hits in each of the search engines. The measures we have used are precision and cumulated gain. Precision is based on a binary scale and cumulated gain is calculated by means of a non-binary relevance scale.

The aim of my bachelor?s thesis is to investigate, through a literature review, changes in the distribution of filamentous algae as well as the general species composition of macroalgae and diatoms in Swedish eelgrass meadows. I have also studied the possibility of tracking these algae and diatoms in eelgrass meadows using eDNA methodology. The focus has been on linking these changes to climate change factors such as eutrophication, temperature increase, and anthropogenic emissions, and how these affect the health of eelgrass meadows and their ecosystem services, such as a carbon sink and biodiversity support. The results show that filamentous algae have increased markedly in coverage in Swedish coastal areas between 1980 and 2021, especially in sheltered bays, indicating that altered environmental conditions favor these fast-growing species. Genetic tracking using eDNA demonstrated that there are functional primers for many species, particularly among brown algae and red algae, whereas green algae require more specific primers due to greater genetic variation.

More than 1000 Swedish Warmblood foals are shown every year at foal inspections which are arranged around the country. Six traits are evaluated at these inspections: type, head-neck-body, correctness of legs, walk, trot and canter. No previous genetic studies have been done on the data from these evaluations. The purpose of this study was to do genetic analyses of the traits which are evaluated at foal inspections. The purpose was also to see if there are any correlations between the results of the foal inspections and the results from the tests of three-year-old horses.