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1103 Uppsatser om Genetic disease - Sida 33 av 74

Blodtryck hos förskolebarn korrelerar med BMI redan från 12 månaders ålder

The purpose of this study was to describe how adolescents aged 12-18 years with inflammatory bowel disease experience their illness and what coping strategies they use to manage their illness and improve their wellbeing. The method used was a descriptive literature study, and the result of the study included 15 scientific articles. Our results showed that IBD affected the adolescent?s everyday life and social life with friends, family and activities. The adolescents also reported that they experienced a feeling of vulnerability, altered body image and that they saw themselves as different from healthy subjects.

Optimization of Lentivirus Production for Cancer Therapy

Vectors based on lentivirus backbones have revolutionized our ability to transfer genesinto many cell types. Lentiviral vectors integrate into the chromatin of target cells and do not transfer any viral genes causing vector replication. Both of these features arecommonly used in gene therapy and have been used clinically in individuals sufferingfrom cancer, infections and Genetic diseases. It has been discovered that T-cells can be genetically modified to be used as effective weapons against cancer: therefore virus mustbe produced to deliver the gene of interest into the T-cells. In this project, lentiviralvectors have been produced to transfer the gene coding for a chimeric antigen receptor(CAR) which is directed to CD19 on B-cells.

The perception of information among women with breast cancer

Background: Breast cancer is one of the most common cancer diseases among women worldwide. Breast cancer brings fear into many womens? life. It is a threat against life, but also to the psychological health, self-esteem and the female identity. Aim: The aim of this literature review was to describe newly breast cancer patient?s perception of information provided by healthcare personnel.

Mellan pekpinnar och retstickor : om mobbning bland barn på 1930 och 1940- talet

In what way were children in the 1930s and 1940s mean to each other, in which ways did theytease and bully one another? And what were the adults part, how did they react to thechildrens spite towards each other and did they do anything to stop it?These are the questions which have been addressed in this essay. In the answers given to us,by a survey in which 42 persons born in the 1920s and 1930s were asked, we have learned,that during the 1930s and 1940s when these children went to school, bullying did'nt occure asmuch. Not as they can remember today.We have also learned that it was mostly boys who were bullied, both mentaly and physical,with punches, being pushed, being laughed at and by being forced to do things they did notwant to do, such as stealing.The most common reasons for being bullied was that the children came from poor families,had ragged clothes, where dirty or had a physical disease such as cronical bronchitis.There where not many children who talked about being bullied with a teacher and the surveytells us that they didn't had any supervisors on the school yard.A number of the questioned answered that they thought that teachers had favourite students inthe classroom and they tell us stories in which teachers used corporal punishment, which waslegal at this time..

Transfetter från idisslare - och dess inverkan på blodlipidprofilen hos friska män och kvinnor

Sahlgrenska Academyat University of GothenburgDepartment of Internal Medicine and Clinical NutritionAbstractTitle: Trans fatty acids from ruminants - and its effect on blood lipidprofile in healthy men and womenAuthor: Sophie Berg and Sara KarlssonSupervisor: Henriette PhilipsonExaminer: Anna WinkvistProgramme: Dietician study programme, 180/240 ECTSType of paper: Examination paper, 15 hpDate: May 23, 2012BackgroundCardiovascular disease is the most common cause of death in Sweden. It is well known that thereis a link between high consumption of industrial trans fatty acids and cardiovascular disease, buthow natural trans fatty acids affect us remains uncertain.ObjectiveThe purpose of this article is to, based on the currently available scientific evidence, concludewhether an intake of trans fatty acids from ruminants generates an effect on the bloodlipid profile of healthy men and women.Search strategyRCT articles were obtained through searches in databases such as PubMed, The CochraneLibrary, and Scopus. Keywords used were "ruminants" AND "Cholesterol" AND "Trans FattyAcids" and "ruminants" AND "Blood Lipids" AND "Trans Fatty Acids".Selection criteriaInclusion criteria were RCT studies conducted on healthy people who did not receive medicationfor hyperlipidemia. Moreover, the results were to be based on fasting blood samples, where atleast ten hours of fasting preceded the analysis of the blood lipids.Data collection and analysisThe search generated eight studies. These were graded according to SBU:s Granskningsmall förrandomiserad kontrollerad prövning, after which four studies were selected.

Finns det ett samband mellan ökad mjölkproduktion och mastit?

The purpose of this study is to describe melanotic tumours and the pathogenesis of these tumours. The focus of this study is on differences between benign and malignant tumours as well as the prognosis one may expect when diagnosing this disease. The mechanisms responsible for the occurrences of the tumours are not yet fully understood. It is believed that factors such as chronic trauma, infections, medications and hormones affect the cell mechanisms in some way. Determinants of the malignancy of the tumour are not completely known.

Könsselektering av spermier från lantbrukets husdjur

Millions of preselected progeny have been born since the development of The Beltsville Sperm Sexing Technology 1986. The method is based on flow cytometry and sorting is done on the basis of DNA difference of the X- and Y-chromosomes. Preselection of progeny provides an opportunity to obtain genetic gain and increased production as well as increased animal welfare and decreased environmental impact. However, the method is associated with low fertility, high costs and uncertainty whether the sorting process contributes to DNA damage and thereby results in genetically impaired progeny. Today, sex sorted sperm is only commercially available in the bovine industry, due to the fact that bull sperm is more suitable for selection than sperm from other species.

Prevention of diabetes type 2 among children and adolecents : Literature rewiew

The objective of this literature study was to describe the nurse?s preventive actions to prevent diabetes type 2 among children and adolescents in school age. It emerged from the analysis that the nurse is working according to three pillars; screening, lifestyle changes and counselling/education. This result showed that what often increase difficulties when working with screening are: undefined guidelines, lack of time and resources. Overweight/obesity is one of many indicators to develop diabetes type 2, therefore it is important that both BMI and waist are measured.

Aortic Body Tumors in Dogs

The purpose of this essay was to review the literature and describe the patophysiology, diagnosis, microscopic and macroscopic appearance of aortic body tumors in dogs. The tumors originate from the chemoreceptor organs situated at the base of the heart. The chemoreceptor organs are neuroendocrine cells responsible for surveillance of changes in e.g. the blood pH. Aortic body tumors are rare and represent 7 % of the total cases of primary cardiac tumors in canines.

Utmattningssyndrom och KASAM. En möjlighet till en ökad känsla av sammanhang?

Some people who recovered from exhaustion disorder report that their lives feel more meaningful after the disease than before, despite residual symptoms and difficulties. This experience of increased meaningfulness has been linked to sense of coherence, SOC. The research question was whether individuals with exhaustion disorder at onset has a weak SOC, and if there is a general increase towards a higher SOC value ??during the recovery process. In a cross-sectional study, data were gathered on the SOC value via the SOC 29 form.

En jämförelse mellan versionerna 1.2 och 2.0 av WAP

The ability to tackle NP-hard problems has been greatly extended by the introduction of Metaheuristics (see Blum & Roli (2003)) for a summary of most Metaheuristics, general problem-independent optimisation algorithms extending the hill-climbing local search approach to escape local minima. One of these algorithms is Iterated Local Search (ILS) (Lourenco et al., 2002; Stützle, 1999a, p. 25ff), a recent easy to implement but powerful algorithm with results comparable or superior to other state-of-the-art methods for many combinatorial optimisation problems, among them the Traveling Salesman (TSP) and Quadratic Assignment Problem (QAP). ILS iteratively samples local minima by modifying the current local minimum and restartinga local search porcedure on this modified solution. This thesis will show how ILS can be implemented for MSA.

GSM-baserat larm

The ability to tackle NP-hard problems has been greatly extended by the introduction of Metaheuristics (see Blum & Roli (2003)) for a summary of most Metaheuristics, general problem-independent optimisation algorithms extending the hill-climbing local search approach to escape local minima. One of these algorithms is Iterated Local Search (ILS) (Lourenco et al., 2002; Stützle, 1999a, p. 25ff), a recent easy to implement but powerful algorithm with results comparable or superior to other state-of-the-art methods for many combinatorial optimisation problems, among them the Traveling Salesman (TSP) and Quadratic Assignment Problem (QAP). ILS iteratively samples local minima by modifying the current local minimum and restartinga local search porcedure on this modified solution. This thesis will show how ILS can be implemented for MSA.

Familjens situation då barnet insjuknar i Diabetes typ 1 - Litteratursammanställning

Background: Diabetes mellitus Type 1 is one of the most common chronicle diseases in childhood. This signifies big changes in the daily life for the child and its family. Aim: The aim of the study was to illustrate the family?s situation when the child falls ill in Type 1 diabetes. Method: The search for literature has been done both manually and in databases.

Hygien, städning och desinfektion inom smådjurssjukvården :

The aim of this report is to create an easily accessible guide to basic hygiene, cleaning and disinfection within the small animal practice. It is based on a literature study, using mainly research from the public health sector, due to the lack of relevant scientific reports within the veterinary field. To prevent the spread of infectious diseases it is important that the staff understands the importance of basic hygiene. Hand hygiene and disinfection and cleaning with water and detergent combined are the most important routines to prevent spreading of disease. In conclusion the differences between the veterinary and the public health sector are small, but some basic differences exist due to the nature of the patient?s needs.

Genetiska och epigenetiska samband mellan näringsförsörjning och fertilitet hos mjölkkor

The dairy cow?s ability to resume estrus after calving and to conceive is affected by their metabolic status after calving. For high yielding cows there is a high risk that the feed intake will not be sufficient to cope with the increased energy demands after calving, and the cow will end up in a state of negative energy balance. Energy balance can be measured in various ways, for example by body condition score or by plasma concentration of several metabolic hormones and metabolites. After calving, endocrine pathways stimulate tissue mobilization; insulin signaling is blocked, the concentration of insulin-like growth factor-1(IGF-1) and leptin decreases, and the concentration of growth hormone (GH) increases.

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