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1103 Uppsatser om Genetic disease - Sida 20 av 74
Upplevelser av att vara anhörigvårdare till en person med demenssjukdom : En litteraturstudie
The purpose of this study was to describe the experiences of being a family caregiver for aperson with dementia. A further aim was the inclusion criteria and data collection methods inthe studies presented, and how this may have affected the results of the studies. The methodwas a descriptive literature study with qualitative approach. Data were collected throughdatabases Cinahl and Pubmed using the words: dementia, knowledge, information, support,caregivers, coping, spouses, experiences and family caregiving. Keywords were combined indifferent ways in order to refine the search.
Livskvalitet hos vuxna patienter med astma :
Background: Quality of life is a concept of individual meaning which is perceived differently depending on the person experiencing it. To have a chronic disease in the lung, such as asthma, has an effect on the quality of life. Asthma affects people of all ages. It is a disease that causes a constriction in the patients? airways which leads to a feeling of suffocation which in turn produces a feeling of anxiety.Aim: The purpose is to illuminate which factors affect the quality of life in adult patients with asthma.Method: This is a literary review based on ten articles, both quantitative and qualitative, from four different continents.
Brucellosis in small ruminants : a seroprevalence study in peri-urban farming around the region of Dushanbe, Tajikistan
The mountainous Central Asian and former Soviet country Tajikistan is the least advantaged country economically among the former Soviet Union states. Approximately 6.5 % of the land is arable in a country where roughly 80 % of the households typically own small numbers of sheep and goats. Management practices and animal husbandry in the villages such as uncontrolled breeding, mixing of animals on pastures favor transmission of infectious diseases.
Brucellosis is a zoonotic bacterial disease caused by Brucella spp. The disease is endemic in Tajikistan. B.
Växtinventering och skötselåtgärder : en studie av Rektorsgårdens trädgård i Uppsala
The Bovine respiratory syncytial virus (BRSV) causes bronchiolitis and interstitial pneumonia, predominantly in calves, and is a major cause of bovine respiratory disease worldwide. In humans, BRSV is paralleled by the closely related Human respiratory syncytial virus (HRSV), an important cause of respiratory disease, most severe in infants.The clinical signs and pathology during RSV infection is caused, not only by the direct effects of viral replication, but also by the response of the host immune system. The immunopathology of RSV has long obfuscated our understanding of the disease, and development of effective treatment and vaccines will be very difficult until greater knowledge is gained.One of the components of the immune system that has come into focus in RSV research the last few years, is the Toll-like receptor 4 (TLR4). The TLR4 receptor is well known as the receptor that binds lipopolysaccaride (LPS), and initiates the host response to bacterial infection. Recently, it has been shown that the fusion protein of RSV also interacts with, and up-regulates the expression of, the TLR4 receptor.
Undersökning av retrobulbärområdet på hund med hjälp av ultraljud :
This study was performed in order to investigate the difficulty in diagnosing retrobulbar disease with ultrasound.
A retrospective study was accomplished to investigate the use of ultrasound in patients with suspected retrobulbar problems, and how often the examination is diagnostic. The computer based patient files, at the University of Agricultural Science in Uppsala, were searched for dogs with suspected retrobulbar disease. During 1999-01-01-2004-04-14, 14 patients fulfilling the search criteria were found. The patient records were studied, and the written reports from the ultrasound examinations were compared with the printed pictures from the examinations.
Surveillance of Geomyces destructans in Swedish bats and Bat Hibernacula
White-Nose Syndrome, WNS, is an emerging fungal disease in the Northern American bat population causing mass mortality in infected hibernacula. Geomyces destructans is a newly discovered psychrophilic fungus causing WNS but the pathogenesis and epidemiology of the disease is not yet fully clarified. Geomyces destructans has been found in Europe but has not been a cause of mass mortality there. This study is the first investigation done to see if G. destructans is present in Sweden.
Alfa-linolensyra från linfröolja och dess påverkan på blodtrycket -En systematisk översiktsartikel
Sahlgrenska Academy at University of Gothenburg Department of Internal Medicine and Clinical NutritionAbstractTitle: Alpha-linolenic acid from flaxseed oil and effects on blood pressure ? A systematic reviewAuthor: Christine Hårdfelt och Liduina van SitterenSupervisor: Helen LindqvistExaminer: Anna WinkvistProgramme: Dietician study programme, 180/240 ECTSType of paper: Examination paper, 15 hpDate: April 9th, 2014Background: High blood pressure is strongly associated with an increased risk of developing cardiovascular disease, particularly stroke. ALA-fatty acids have previously been associated with decreased blood pressure. Flaxseed oil is very rich in these fatty acids and has also been highlighted as an affordable and sustainable source.Objective: To investigate whether ALA-fatty acids from flaxseed oil may affect blood pressure in people with high risk for cardiovascular disease.Search strategy: Two searches in PubMed and Scopus were performed. The sample was specified by using specific keywords.Selection criteria: The criteria for inclusion of studies required that flaxseed oil was compared with a control and that blood pressure was measured as an endpoint.
Undersökning av Brenneria salicis förekomst i pilar i Skåne : Är ?Watermark Disease? nära?
Bakterien Brenneria salicis lever i xylemet hos bland annat arter av Salix. Under vissa omständigheter ger den upphov
till en vissnesjuka, internationellt känd som Watermark Disease. Utbrott av denna har aldrig rapporterats från Sverige,
men då forskning visat att bakterien ofta uppträder som endofyt och inte patogen uppstår frågan om själva bakterien
ändå inte finns i Sverige utan att orsaka vissnesjuka. Samma forskning visar nämligen att yttre faktorer kan förmå
bakterien att övergå från en endofytisk till en patogen livsstil. Under antagandet att klimat och markanvändning är
sådana faktorer och vetskapen att de är i förändring blir det angeläget att undersöka B.
A retrospective study of bitches with pyometra and mucometra medically treated with aglepristone
Pyometra is a common and life threatening disease of intact bitches. The disease is caused by a hormonal influence on the uterus in combination with a bacterial infection. The most common treatment is ovariohysterectomy, but several medical options are available to maintain fertility or avoid surgery and anaesthesia. Drugs that can be used for medical treatment are for example progesterone-receptor antagonists, prostaglandins and dopamine agonist. The present study focused on treatment with the progesterone-receptor antagonistaglepristone in combination with antimicrobial therapy.
Kronisk mitralisinsufficiens hos hund : samband mellan graden av klaffinsufficiens och det arteriella blodtrycket
Myxomatous mitral valve disease is a common disease in older dogs of small- to medium-size breeds. The mitral valve, and less commonly the tricuspid valve may be affected which causes them to leak blood from the ventricle to the atrium of the heart during systole. With increasing severity of mitral valve leakage the forward stroke volume ejected into the aorta decreases, which may lead to an increase in blood pressure in the pulmonary vein resulting in pulmonary edema. A decrease in cardiac output may lead to a decrease in blood pressure, but the body may respond in order to normalize the blood pressure. Franzén showed in 2007 that the systolic blood pressure was increased in dogs with severe mitral insufficiency.
Höftledsdysplasi och armbågsledsartros hos labrador retriever med känt radiologiskt status av höftleder och armbågar : en tredje uppföljande studie
Joint-related diseases including hip dysplasia (HD) and elbow arthritis (ED) can in advance cases lead to that the dog has to be put down, and these diseases are also the cause to expensive veterinary treatments of many large breeds, including Labrador Retrievers. The aim of this study was to make a follow-up study on the 271 Labradors, who previously participated in a study on the effect of nutrition and exercise on hip and elbow status in a birth cohort born year 2000. That study investigated the relationship between nutrition, exercise, and HD and ED. A follow up study on the same dogs at 5-6 years of age investigated the clinical effects of the radiological hip and elbow status at 1 years of age and if was effected by body condition score. This study took place in 2011-2012 and 187 Labrador retrievers participated.
Development of a real-time RT-PCR for quantification of bovine TLR4 mRNA and evaluation of its use during a BRSV vaccine challenge
The Bovine respiratory syncytial virus (BRSV) causes bronchiolitis and interstitial pneumonia, predominantly in calves, and is a major cause of bovine respiratory disease worldwide. In humans, BRSV is paralleled by the closely related Human respiratory syncytial virus (HRSV), an important cause of respiratory disease, most severe in infants.The clinical signs and pathology during RSV infection is caused, not only by the direct effects of viral replication, but also by the response of the host immune system. The immunopathology of RSV has long obfuscated our understanding of the disease, and development of effective treatment and vaccines will be very difficult until greater knowledge is gained.One of the components of the immune system that has come into focus in RSV research the last few years, is the Toll-like receptor 4 (TLR4). The TLR4 receptor is well known as the receptor that binds lipopolysaccaride (LPS), and initiates the host response to bacterial infection. Recently, it has been shown that the fusion protein of RSV also interacts with, and up-regulates the expression of, the TLR4 receptor.
Selen och incidens av typ 2-diabetes - en systematisk översiktsartikel
Background: Type 2 diabetes is a disease which causes vascular damage, stroke and premature death.Oxidative stress may play a role in the development of insulin resistance and diabetes. Selenium is amineral involved in the protection against oxidative stress, and has been thought to be favorable in theprevention of the disease. However, this has changed since trials observed positive correlationsbetween high selenium levels and incidence of type 2 diabetes.Objective: To examine the studies that investigates seleniums effect on the incidence of typ 2 diabetesSearch strategy: Searches have been done in PubMed and Scopus.Selection criteria: Included studies were human studies in English/Swedish with RCT or cohortdesign with the aim to investigate the correlation between selenium and incidence of type 2 diabetes.Excluded studies were studies whose aim was to investigate the role of selenium in patients withexisting diabetes. Studies regarding pregnant women, animals or children and with in vitro design werealso excluded. Of the studies found in Scopus where MeSH terms were available, the ones who did notinclude relevant terms were excluded.Data collection and analysis: Studies were collected according to the aforementioned criteria.
En utvärdering av avelsprogrammet mot kronisk hjärtklaffsdegeneration hos Cavalier King Charles spaniels :
Chronic valvular disease (CVD) is the most common cardiac disease in dogs, which account for 75% of all the cardiac cases. Cavalier King Charles spaniel (CKCS) is the most affected breed and it´s 13th times more likely that a CKCS, between the age of 7-10 years, will die or be euthanized for cardiac disease, compared with other breeds. The prevalence has been proven to bee independent of coat color and weight but highly dependent on age and gender in CKCS.
In 2001 the Swedish Kennelclub and the Special club for cavalier King Charles spaniel created a breeding program against CVD in CKCS. In this program dogs are not allowed to breed until 4 years of age and have to have a heart auscultation without murmurs.
Yngre kvinnors upplevelser av att få en bröstcancerdiagnos och livet därefter
Background: Breast cancer is one of the most common types of cancer in the world and it usually affects elderly women. However, there are between 600-700 cases per year in Sweden where women under the age of 45 are diagnosed. Removal of the breast or part of the breast, hair loss, fatigue and nausea as a result of the breast cancer treatment has an emotional and physical impact on the women?s lifeworld. The nurse should build a relationship with the women to identify and meet their needs. Aim: To describe younger women?s experiences of getting a breast cancer diagnosis and life afterwards.Method: Four biographical books were analyzed to match the aim of the study.Result: The findings were that the women experience similar thoughts and feelings when it comes to living with a cancer diagnosis.