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538 Uppsatser om Gene expression - Sida 6 av 36
Early immune responses to an adjuvant (AbISCO-100) tested in porcine peripheral blood mononuclear cell
Immune stimulating complex (iscom) matrix is a formulation that is used as anadjuvant within research. The capability of the iscom matrix to elicit an immuneresponse when not present together with an antigen has not been extensivelyinvestigated. One way to evaluate the status of the immune system is to measure theamount of cytokines that usually are produced by various cell types during an immuneresponse. The aim of the present study was to evaluate the early immune responses inporcine peripheral blood mononuclear cells (PBMC) after stimulation in vitro with theiscom matrix, AbISCO®-100. The immune response was evaluated by measuring themRNA expression for various cytokines, a chemokine receptor (CXCR4) andregulator of G-protein signaling (RGS16) in porcine PBMC after stimulation withAbISCO®-100 or other inducers like a lipopolysaccharide (LPS) and a CpGoligodeoxynucleotide (ODN 2216) used as controls.
Expression and Purification of Murine Tripeptidyl Peptidase II
Tripeptidyl peptidase II (TPPII) is an exopeptidase which cleaves tripeptides from theN-terminus of peptides. The exact functional role of TPPII is still a matter of investigation. Itis believed that the enzyme is primarily involved in intracellular protein degradation, where itcooperates with the proteasome and other peptidases to degrade proteins into free aminoacids. These amino acids can subsequently be used in the production of new proteins. The aimof this work was to express murine wild type TPPII using E.
Göteborg International Film Festival Fund - Internationell kulturpolitik och strategiskt utvecklingsarbete
The aim of this research is to examine the Göteborg International Film Festival Fund (GIFFF, 1998?2011) as a part of the festival's overall operations, to provide answers to questions about if/how the Fund can be understood as an expression of the festival's fundamental values, and how the Fund can be recognized within the festival's strategic development. The GIFFF is also discussed in relation to contemporary academic studies that interpret Western film funds for the developing countries ? such as Hubert Bals Fund and Fond Sud Cinéma ? as an expression of Eurocentrism.The investigation is based on the contemporary film festival research, previous academic studies on Göteborg International Film Festival, the festival?s printed material ? such as programs and press releases ? as well as interviews with the former festival director Gunnar Bergdahl, who initiated the Fund, and festival editor Ulf Sigvardson, who ran the Fund during its final years of existence.The conclusions are: The Fund's objectives ? such as to support filmmakers and film schools in the developing countries, and also to screen their films at the festival ? can be seen as a broader interpretation of the vision that was determined by the festival founders, that the festival should be a platform for independent filmmaking and also help screen the films that otherwise would not reach the Swedish audience. Also, the Fund was a significant part of the festival's expansion strategies during the 1990s.
Genetiska studier på fågelinfluensa :
In the spring of 2006 we had our first outbreak of avian influenza of highly pathogenic H5N1 (HPAI) among wild birds in Sweden. This disease have impact on poultry industries world wide. Sporadically the virus infects other species than birds and we now know it can even cause fatal infection of humans. There are not yet any confirmed cases of transmission of the disease between humans though a suspected case in an Indonesian family is under investigation. If a mutation occurs that changes the pathogenicity and host affinity to humans we are at a risk of a new pandemia, perhaps like the Spanish flu in 1918-1920.
Fine-Mapping of Equine Multiple Congenital Ocular Anomalies on horse chromosome 6
Multiple Congenital Ocular Anomalities (MCOA) is a genetic disease that affects primarily Silver coloured horses of breeds such as the Rocky and Kentucky mountain horses. In these breeds the Silver dapple colour is very popular leading to an increase of affected horses. The major feature of the disease is ocular cysts of variable size. Large cysts also lead to a variety of secondary syndromes, for example retinal detachment. In previous studies the locus for MCOA has been mapped to an interval of 420 kb on equine chromosome six.
Lactobacilli in the gastrointestinal tract of dog and wolf : isolation, identification and characterization of L. reuteri
Since the first wolf was taken as a companion animal a lot have happened with the biology of these animals. Is it possible that changes in the gut microbiota of the domestic dog are involved in the increasing numbers of animals with gastrointestinal disorders? Probiotics have been proven to promote the immune system of dogs by increasing concentrations of neutrophils and monocytes, decreasing the fragility of erythrocytes and increasing the serum IgG concentrations. Probiotics have also been shown to improve the fecal consistency, fecal dry matter and defecation frequency of dogs. The aim of this study was to find out if the bacterial counts in the gut of dogs differed from the gut of wolves, with the focus on lactobacilli.
Frihet till hat? : Hatbrott, rasistiska organisationer och inskränkningar av yttrandefriheten
The present paper is part of a project carried on by the Swedish Section of the International Commission of Jurists. Sweden has ratified several major international human rights instruments. Most of the rights are covered by national law, and only in exception is there a discrepancy between national and international law. Such a discrepancy is found in the UN Convention on the Elimination of all forms of Racial Discrimination, in which the State parties agree on penalizing and prohibiting the founding of and participation in racist organizations. Sweden is not complying with this statute, despite the fact that the government has ratified the convention.
Bris - ett golv
The aim with the project was to portray something to step on. Its purpose has been to experiment and explore the interaction between pattern, structure, material and colour for something to be applied on a floor. Focus has been on esthetic expression and not the creation of some¬thing for a specific environment or audience. My goal was also that this project would illustrate the importance of the floor to create a certain atmosphere in a room.The project was divided into three phases. The first one was the experimenting and exploring phase, where the goal was to find an expression.
Tapetmönster - en kollektion av form & färg i rum
The character of a pattern carries through to the context in which it is placed. Each pattern tells a story. By interpreting our surroundingenvironments we become inspired, and the patterns in turn can become part of our own narratives. This project was fuelled by my fascination and desire to explore patterns. My method of exploration was based on prior knowledge of patterns and interior design.The question became how can I apply my knowledge of interior design to pattern design and how could I best translate the brief intoa language of colour and shapes? The aim was to develop my knowledge of pattern design as well as to use this opportunity to combine my design methods with those of a professional designer.
Stig Dagerman - Existentialisten : En jämförande studie mellan De Dömdas Ö och fem existentialistiska tänkare
Is the Swedish author Stig Dagerman an existentialist? This work takes a close look at Dagerman?s novel Island of the Doomed to see if it is possible to consider it an expression of existentialist thinking and to see if it interacts with any specific existentialist tradition. Dagerman?s novel was compared with select works of five existentialist thinkers ? Søren Kierkegaard, Martin Heidegger, Jean-Paul Sartre, Albert Camus and Karl Jaspers, all read in the light of the four categories of existentialistic thinking identified by the Swedish scholar Lennart Koskinen. All the four categories appeared to be central themes within the novel and a few subcategories were identified.
"Vem har sagt att man ska tro?" : En kvalitativ studie av religiositet på svenska landsbygden
AbstractThe aim of this study is to examine how individuals, part of a rural Christian parish,express their religiosity and beliefs in a Swedish context. Furthermore this study seeksto understand these religious expressions through different views on social construction,secularization and the privatization perspective, such as lived religion, in particular. Byusing qualitative interviews with 8 individuals analyzed with the theories mentionedabove my results show that secularization has provided many individuals with aChristian identity, however, not necessarily a Christian faith. Instead several of theparticipants show a self-developed religious expression not automatically connectedwith Christian religious practices. One of the participants has, despite a Christiansocialization, developed a non-religious identity.
Flygfänas skog. Illustration möter rumslighet på barn och ungdomssjukhuset i Lund
Flygfänas skog is a project where illustration meets spatiality. The work is about how section 62of the Children and Youth Hospital (BUS), at Skåne University Hospital, in Lund can useillustration as a compliment to their premises. Today, the hospital has difficulties to deal with theolder children patients at the hospital in a good way because the expression that is there today,mostly only appeals to the younger patients. Previously, there has been some kind of decorationon the department and the staff thought that this is boring, is a problem in that in many placesthere are stickers of child characters posted on the walls. This and other installations that cut outletters, face off, and symbols have made sense in the department becomes fragmented, ill andchildish.
Importance of epigenetics in animal breeding : genomic imprinting
ABSTRACTThe aim of this study was to give an overview of the evidence for genomic imprinting in livestock and other mammals as well as outline the potential use of gene imprinting in livestock breeding. Epigenetics is the mitotical and meiotical partial hereditary variation in genomic activity without any alterations of the DNA sequence. An example of epigenetic regulation is genomic imprinting where one allele?s expression differs depending on which parent it was inherited from. These parent-of-origin effects are currently overlooked in livestock production.
Är prostitution ett uttryck för brist på jämställdhet? : En studie av den unika sexköpslagen
Our purpose with this essay is to find explanations to the genesis of the Swedish law against prostitution now in power, known as Sexköpslagen 1998:408. We enter deeply into the official reports behind the law. This Swedish law implies that in a sex trade a crime is committed only by the consumer, and not by the seller. Our essay will result in an analysis of what sexköpslagen is an expression for. Our assumption is that the so called ideology of (gender) equality in Sweden might be a part of the explanation to the genesis of sexköpslagen.
Ordning och reda i skolan : En diskursanalys av uttrycket ordning och reda
In media the debate about discipline and order in school is widely heard. A politician, some teacher or a representative from the teacher´s union, most often speaks these words. The interest for these issues seems to be persistent.This study is primarily about the expression ?discipline and order?. The aim is to find out how the expression ?discipline and order? is used in the investigated material.