The RECK gene is a relatively new discovered gene with important implications for cancer research. The research has been primarily concentrated on the human gene with the ultimate aim to identify the invasive characteristics. Up regulated RECK is linked to significantly prolonged survival rates in patients with severe forms of malignancies. RECK is normally expressed in all cells of the body and has an important role in the balance between destructive and constructive features of the extracellular matrix. The RECK protein is a membrane-bound glycoprotein that inhibit matrix metalloproteinases which has the function of breaking down the ECM. There is a significant correlation between RECK gene expression and the formation of new vessels, presumably via the mediation of VEGF which is an important and powerful inducer of angiogenesis.

This has been a thesis work for an bachelor degree at Umeå university. The work has been done at LKAB?s facilities in Kiruna and its main purpose has been to investigate and construct some conceptual designs for replacing a screen with magnetic separation in KA3 concentrator plant. First all information available about magnetic separation was gathered and studies of magnetic separation at the sorting plant and studies of the plant KA3 was conducted. Companies that manufacture magnetic separators were contacted.

This essay is a study of the portrayal of the theme of alienation in Eugene Ionesco's novel The hermit. In my study I examine the different ways in which the theme of alienation is portrayed and how the cause of the narrator's experience of alienation can be found in ideological, psychological and existential conflicts that the narrator has to face. The result is an experience of das unheimliche, a Freudian concept, which is a kind of uncanny detachment that the narrator experiences, when he is put up against an invisible force that lurks in the perifery of the world, which is portrayed in the story. The meaning of the ideological conflict is a portrayal of man's situation in a world that is ruled by capitalism, with marxism as a positive leveler and the meaning of the psychological conflict is a conflict in the narrator's own inner reality. The meaning of the existential conflict is a portrayal of man's situation in a world absent of God.

The Lugnetgymnasium in Falun has a graphic education that supplies a color printer, which is availablefor the students in their hall. The printer is a Ricoh AFC 6513 and it is a model that can handlevariable data. It was bought in the autumn of 2002. The teachers of the graphic education want to makeuse of the variable data function and procure a variable data software. The purpose of this project is toevaluate variable data software?s, so that the most suitable choice of software can be made for the graphiceducation.

The aim of this study was to examine how children in ages 3 to 4 use the public library with the research questions: What does children?s, in ages between 3 and 4, information behavior look like when they visit a public library in leisure time with a parent? What is the nature of interaction between child and parent, child and the staff of the library, and between child and other visitors? What is the function of the cultural tools in relation to the children?s information behavior? The theoretical frame of reference consisted of Lev Vygotsky?s ?the zone of proximal development? and Roger Säljö?s theory about using cultural tools. To answer the questions I have observed 4 children together with their mothers and siblings at a public library. From the result of the observations I found that every child had their own information behavior. Two of the children only used one kind of cultural tool ? books.

The purpose of this paper is to investigate when Swedish and English are used in English teaching and how the pupils view the importance of the classroom language for their language development. My research questions are ?In what situations is Swedish and English respectively spoken during the English lessons?? and ?What are the pupils' opinions concerning the significance of English and Swedish in the classroom for their language development??. To answer my questions, I have used relevant theoretical research and conducted two observations and two group interviews in a secondary school. The observations have given me an example of how it can function in the classroom and the interviews have given me the opportunity to hear the pupils' different perspectives on how it is done in the classroom and their different opinions concerning this matter. According to the research, it is of great importance that the pupils are offered the opportunity to use the English language as much as possible in the classroom.

The coproduct, dried distillers grains + solubles (DDGS) from ethanol production based on wheat contains much rumen degradable protein and fiber with low digestibility. To compliment this quality in an effective way a grass silage low in protein and much digestible fiber is needed. The aim of the study was to investigate the effects of adjusting the crude-protein concentration and fiber quality of the silage when feeding DDGS and of varying the inclusion level of DDGS, when feeding the adjusted grass silage, on intake, milk yield and composition, faecal traits and feed efficiency. Four different total mixed rations were compared. The normal grass-clover silage had a crude protein content of 17,8 % and an NDF content of 46,2 % of dry matter. The adapted grass silage had a crude protein content of 14,6 % and an NDF content of 52,9 % of dry matter. The diets were formulated to have similar nutritional content except for A + 4 which had a higher content of rumen degradable crude protein and a lower concentration of NDF.

The purpose of this Master?s thesis is to examine the function of public libraries on the social web, focusing on reading promotion and reading stimulation. For an understanding of the larger context regarding public libraries on the social web, we conducted online interviews via email with people in the Swedish library profession, together with a content analysis of various texts on the subject found in library journals and on the Internet. Furthermore to identify the public library's practice on reading promotion and reading stimulation on the social web, we did interviews with librarians at a public library on their use of a blog for this purpose, together with a questionnaire handed out to the library's users on their use and conceptions of the blog.The conceptual framework of this study consists of four key aspects in the theoretical and empirical definition of Library 2.0 presented by Holmberg, Huvila and Widén-Wulff. The results showed that the public library can create a substantial value through its use of the social web, but it?s necessary to have a clear vision of the desired outcome.

National libraries hold large, valuable repositories of often unique materials. How can we ensure that the knowledge is accessible without endangering the materials that hold the knowledge? Digital preservation is meant to solve this problem. With more and more material being accessible digitally, users are expected to do more and more of the finding on their own, instead of being guided by librarians. What kind of knowledge do the librarians have, that cannot be mediated through a system? How is the knowledge of experienced librarians passed on to new librarians? What is the difference between physical and digital materials? I have interviewed senior and junior librarians of Det Kongelige Bibliotek in Copenhagen, Nasjonalbiblioteket in Oslo, the National Library in Helsinki, and Kungliga Biblioteket in Stockholm to learn about their journey to knowledge of their collections.

This is a literature study of learning mathematics in general and algebra in particular. The goal is to explore and investigate the learning procedure and the difficulties pupils have with their understanding. Furthermore, to understand what qualities is requested of pupils in their effort to be successful in mathematics and algebra. I have also explored different pupil thinking styles in mathematics and what consequences that has on their learning and understanding. Moreover, I have investigated some different learning styles and how they can be addressed in teaching of mathematics in general and algebra in particular.

Ett Film som projekt, en film om ljud, en film om ljudet i film. En film inspelad professionellt med professionella medarbetare. Kandidatarbetet gick ut på både skapa en film inriktad på ljud och skapa ett fungerande filmteam. Arbetet tar upp både det tekniska inom filmljud men även processen i ett filmteam. I arbetet följer vi processen från dess början till dess slut.

As the ability to computerize processes and tasks increase, the proliferation of complex systems in our society continues. How these systems are deployed in the organizations where they are meant to be utilized has been shown to have a large impact on how well they function.In January of 2011 the Enköping hospital initiated the deployment of an IT-support for drug management, a module in the general health care system Cambio COSMIC. Other health care providers in the county, and in the rest of Sweden, have had mixed feelings toward the module. Some have outright refused the module, claiming that it is detrimental to patient safety. One of the arguments for deploying the module in Enköping, however, was that it was needed to improve patient safety.The Enköping hospital is considered to be a well organized institution with good leadership and earlier good experiences regarding IT-systems.

The use of history is the concept of people using and analyzing history in the society for various purposes. Study in this area has largely emerged because there are many different reasons for people and societies to be interested in history. To investigate the use of history, a historical material needs to be present in some form. With this study, I intend to show how older tourist guidebooks can provide such materials of study and therefore I use travel guidebooks about Tallinn released under the USSR (Estonian SSR) between the years 1960 to 1990. The analysis is based on Klas-Go?ran Karlsson's (Professor of History) typology of seven different uses of history: scientific, existential, moral, ideological, political, educational, non-use of history and a commercial use of history.

This thesis has been made in cooperation with Forsheda Stålverktyg AB which develops and manufactures injection moulds and diecasting tools. The main concern has been their Trading-system which provides them with considerable amount of quality lost function.Focus has to however be put on the analysis of the Trading-system due to the fact that this has previously meant various quality issues for the company.This thesis treats quality assurance of the Trading-system, identification of the problems in the process and improvements of these problems.Quality assurance is carried out when a company detects that their quality based costs become too high. Quality based cost are? the costs that would disappear if a company's products and its different operational processes were absolute? (Sörqvist, 2001 p.30, free translation from Swedish). High quality based costs often result in increased quality problems, which can lead to substantial economic loss for the company.This work has resulted in a thorough review of the Trading-system whereupon problems have been identified.

This study is an attempt to investigate religious perceptions and its development, function and connection to religious practise within the Swedish extreme metal scene. This is performed mainly by a qualitative method of investigation, studying lyrical content published on a number of extreme metal albums, thereafter relating the lyrical progression to the progession of the scene as a whole and also to the development of individual religious belief and practise.The lyrically expressed manifestations of religiosity within the extreme metal scene prove to be related to religious practise in some cases, most visibly in the Christian parts of the scene.The study also indicates that development of religious expression often is evident regardless of religious preference. This development also regularly relates to an increase in musical evolution and prowess often achieved with increased age and maturity.Musically and lyrically, the extreme metal scene displays transgressive attributes which assist both individual and group in the process of creating identity, meaning and individuality.Experiencing extreme metal, in concert or in the privacy of one´s own home, can be one way of perceiving spirituality in this modern age..