Transdermal drug delivery, besides painfulinjections with syringes, has long been associatedwith small size particle pharmaceuticals, which candiffuse through the skin. This method of drugadministration has only been applicable on a smallnumber of drugs, where active molecules are smalland delivery time should or can be long.Other drug delivery options are oral administrationand injection with hypodermic needles (ordinaryhospital syringes). In oral administration thestomach and liver tend to dissolve the drug and theeffect becomes more difficult to anticipate, anddrug delivery rates difficult to control. Hypodermicneedles are used as a mean of drug injectiondirectly into the bloodstream. This method ispainful and risks infection due to tissue damageand skin penetration.One way to get a painless non-damaging techniquewith high delivery rate that still can delivery largemolecules is to manufacture an array of microscopichollow needles and equip them with a pumping unitthat delivers the correct amount of drugs.This thesis shows the technique and possibility ofmanufacture micromachined needles using low costtechniques of Ion Track Technology (radiation ofheavy ions creates porous materials), electrolessdeposition (non-current activated wet chemistrymethod of depositing metal) and electroplating.

2013 a decision was made that all projects at the Swedish Transport Administration shoulduse BIM (Building Information Modeling) to some extent from 2015. BIM is an approachthat allows for streamlining of projects by the use of a 3D-model created in an early stage ofthe project. The 3D-model can carry information about the facility throughout its life cyclefrom planning to management. The use of a 3D-model can help the project to detect errors inearly stages of the project when it is easy and cheap to fix the error instead of finding theerror in the construction phase when it is costly and time consuming to fix it. 3D-models alsolead to improved communication both within the project groups and with the public.

A secondary and a pioneer tree species can with advantage be included in a mixed stand to increase the use of sunlight. Nitrogen-fixing plants have been shown to increase the supply of nitrogen in the soil by, for example, litter fall. This deposition acts as a biological fertilization, which may be used by non-fixing plants. Alder is a nitrogen-fixing, pioneer tree species that loses its nitrogen-rich leaves late in the autumn. The aim of this study was to examine the effect on the total volume of production, when different proportions of nitrogen-fixing Alder were part of spruce stands.

Snö och permafrost är två interagerande komponenter i Kryosfären. Studien undersökersnödjupets representativitet vid marktemperaturmätningar under snötäcket (BTS) föridentifiering av permafrost i Tarfala, norra Sverige. Snödjupsmätningar har utfördes itvå korsande 20 m transekter i nordsydlig (NS) samt östvästlig (ÖV) riktning utifrån enBTS-punkt. Totalt har 37 BTS (snödjup > 80 cm) med tillhörande snödjupsmätningarregistrerats och analyserats. Snödjupet varierar både lokalt kring mätpunkten ochregionalt i mättransekter men är ändå ett representativt snödjup för en punkt.Representativa BTS, sett ur ett snödjupsperspektiv, bör registreras på platser medmåttlig snödjupsvariation som på platser med homogent markunderlag, vindskyddadeområden, lä bakom ryggar och sluttningar vinkelräta mot den dominerandevindriktningen.BTS provplatser bör också ta hänsyn till de mest förekommande klasserna avparametrarna altitud, sluttning och slutningsriktning för att erhålla representativa BTS.Detta baserat på jämförelse mellan två strategier för insamling av BTS genompermafrostmodellering mellan två dataset.

Trafikverket vill ta reda på hur de skaimplementera BIM (Building information modeling) som ett arbetssätt i sinorganisation vid projektering, byggande och förvaltning. Syftet med det härexamensarbetet är att ta reda på hur Trafikverket kommunicerar med BIM-modelleridag och hur man kan utvecklas.Det är få människor i anläggningsbranschen som idag har erfarenhet av att arbeta med BIM. Även i de projekt som jobbar med BIM idag så behövs det alltid en BIM-samordnare som håller i trådarna. För att få ett bra slutresultat så måste kommunikationen i ett projekt fungera bra. En förutsättning för detta är att alla inblandade parter har samma mål med projektet, t.ex.

This thesis was performed at Indusec ABin Stockholm. Indusec AB is a companythat develops security solutions.Together with the Police of Sweden theyhave gotten the assignment to develop anapplication based on one of theiralready existing product Inferno soundbarrier. This application is supposed tobe mounted on a ballistic shield thatthe police use, the application consistsof a speaker box (the sound barrier) anda trigger with wire. The trigger withwire is the part that will be addressedin this thesis. The application willthen be used as a tool to surprise atarget at various skirmishes.The project consists of three majorphases, pre-study, concept generationand modeling.

EGR (Exhaust Gas Recirculation) är en teknik som används för att minska utsläppen av kväveoxider från förbränningsmotorer. Med EGR återcirkuleras delar av avgaserna till motorn vilket medför att sot och andra partiklar samt sura ämnen återförs. Därmed ställs det nya krav på motorns material och det gäller framförallt motorns cylinderfoder och kolvringar som detta arbete inriktar sig på. Syftet med arbetet är att med hjälp av en nötningsrigg sålla mellan olika material och ytbeläggningar under EGR-liknande förhållanden samt att undersöka olika faktorers inverkan på slitaget. En nötningsrigg av typen pinne-platta används där en del av en kolvring förs fram och tillbaka över en provbit från ett cylinderfoder.

This project has as main goal to study the influence of the coating thickness, deposited by arc-PVD- technology, on the wear resistance of coated cemented carbide inserts in three different turning operations. An additional effort has also been made to develop a new test method for evaluating flank wear resistance. Three different coating types (Coating A, Coating B and Coating C) have been studied in three distinctive thicknesses (2, 4 and 6 µm) for each type. For two of the coating types (Coating A and B) special studies has been done with the thickest coating, creating two additional coating versions of the thickest coating, by changing various deposition parameters, with the aim to enhance the cohesive properties of the coating and lower the residual stresses at the cutting edge. The results show increased crater wear resistance with increased coating thickness for all coating types, but the amount of increase changes with coating type (Coating A>B>C).

The purpose of this study was to examine young offenders? attitudes towards crime, and to the penalty they have been sentenced to as juveniles. More specifically its aim was to examine an intervention program called Galaxen, specifically used  to deal with  juveniles  in Växjö. This intervention program consists mainly of conversations with social workers from social services,  aiming  towards  better  self-awareness  and  the  ability  to  understand  the  consequences  of one?s actions.

Denna rapport tar upp teorier och metoder kring användbarhet i skapandet av en Flash-applikation. Rapporten beskriver steg för steg i skapandeprocessen, hela vägen från att ta fram behov och användningsområde till att skapa innehållet och slutligen en utförlig redogörelse för hur applikationen sammansätts. Metoderna som använts är huvudsakligen ITK (Identity Tool Kit) och scenarier enligt Alan Cooper. Vidare har metoder för hopsättning och visualisering av applikationen använts med stöd av Nielsen och Raskins användbarhetsprinciper. Resultatet visar att för att använda ITK i syfte att kartlägga en verksamhet, kräver detta en stor förståelse och modifikation av denna.

The company Olofsfors AB manufactures drive belts for forest machinery, known as ECO-Tracks, and abrasion-resistant steel and cutting edges for graders, excavators and tractors, known as Bruxite and SharqEdges. Manufacturing these products requires the steel to be heated and molded, then submerged in water and hardened. The water used in the hardening of steel is pumped to the process from pits below the floor and then pumped back to the pit after it?s been used. Since the temperature of this water rises after being used to harden the steel the temperature of the pumping pit needs to be adjusted to maintain its setpoint of 21°C.

Mathematical models possible to simulate are of great importance in order to make successful projects in the aircraft manufacturing industry. An aircraft fuel system is very complex, containing pipes, tanks, orifices, valves and pumps. The principal of this thesis is using the tool Easy5, which no longer is considered reliable enough in terms of development and support. This thesis tries to evaluate the Modelica language as a possible alternative to Easy5. To make this evaluation, the components concerned in the fuel library in Easy5 are implemented to the Modelica language.

A lot of mine waste rock and tailings arise from all mining processes and have to be stored in an appropriate way. Tailings are deposited in impoundments retained by tailings dams. The objective of tailings dams is to retain the slurry from the mining process and in that way prevent spill into the surroundings that might be harmful for the environment. Tailings dams are often constructed as staged embankments so that construction costs and demand of materials are spread more evenly over the period of deposition.The objective of this thesis has been to compile information about and evaluate events at Swedish tailings dams and also to develop a collective database for all Swedish mining companies for all tailings dams and all events that occur at tailings dams.Information about 60 events at Swedish tailings dams has been gathered and evaluated. The evaluation has been performed by comparison between and analysis of individual parameters and also by use of a multivariate statistical method called PLS.

With numerous applications in both military and civilian life, the demand for accurate 3D models of real world environments increases rapidly. Using an airborne laser scanner for the raw data acquisition and robust methods for data processing, the researchers at the Swedish Defence Research Agency (FOI) in Linköping hope to fully automate the modeling process.The work of this thesis has mainly been focused on three areas: ground estimation, image segmentation and classification. Procedures have in each of these areas been developed, leading to a new algorithm for ground estimation, a number of segmentation methods as well as a full comparison of various decision values for an object based classification. The ground estimation algorithm developed has yielded good results compared to the method based on active contours previously elaborated at FOI. The computational effort needed by the new method has been greatly reduced compared to the former, as performance, particularly in urban areas, has been improved.

The system tungsten-oxygen has potential of being suitable for decorative coatings since ceramic coatings are often hard and wear resistant, and since modulations in oxygen content or incorporation of small ions could give bright colours. The aim of this report was to investigate the relationship between process parameters and  the properties of the films, with the wear resistance being of special interest.Samples with tungsten to oxygen ratios in the range of 100:0 to 25:75 at% were made using reactive sputter deposition, either with constant gas flow, or gas flow controlled by optical emission of the plasma. The hysteresis of the system, which means that a certain gas flow will cause different pressure and/or target voltage depending on in what way the flow is reached, makes it interesting to control the process where the system makes the steep change from metallic tungsten to ceramic tungsten oxide. This is difficult and thus requires precise control equipment.The samples were analysed using X-ray diffraction, X-ray photoelectron spectroscopy and an empirical wear test suitable for small components like cell phone cover for example, in order to characterize the structure, composition and wear resistance of the coatings. The results could be divided into three groups: (I) tungsten-like, with very low oxygen content; (II) mixed phase and (III) tungsten oxide like, with oxygen content close to 75 at%.