Determination of serum thymidine kinase 1 (TK-1) activity is used as a tumour marker in both human and veterinary medicine. TK-1 is an intracellular enzyme involved in a salvage pathway of DNA synthesis. The expression of TK-1 is cell cycle dependent and the activity increases markedly after the G1 to S transition in the cell cycle and then declines rapidly in G2. The pronounced proliferative activity in tumour cells result in a higher TK-1 enzyme activity within the cell. The fact that the increased TK-1 activity can be measured in serum makes TK-1 a useful marker in diagnostics of neoplastic diseases and it provides information regarding prognosis and treatment effectiveness. In human medicine a radioactive based test is used to determine the TK-1 serum activity.

AbstractThe purpose of this essay was to investigate what thoughts children in preschool and preschool class have about friendship. We also want to investigate what characteristics and which strategies they look for in friendship relationships.  To perform this study we used the following questions as a starting point. Which characteristics do children see as attractive in their cultures?How are friendship relationships affected in different contexts?Can one see a difference in the most important characteristics and strategies between the children in preschool and the children in preschool class? To answer our questions and to reach our purpose we have held group interviews with children in preschool and in preschool class.  We have, in our study, used published scientific literature to get an understanding of what has been presented in relation to this topic in the past.The result shows that the children in preschool and preschool class do differ in certain aspects but also have some similarities on ideas about friendship. Both preschool children and the children in the preschool class are highly competent and skilled at integrating with other children. What divides them is their ways to plan their friendship.

This study examines the cultural factors which necessitated the establishment of The Music Archives of Småland in 1991 in the city of Växjö. I wanted to know the importance of the local music tradition and the role of those people who worked to create an institution such as this. In order to do this I interviewed the chief collector of early folk music, Magnus Gustafsson, and made use of literary sources to devise questions and evaluate the results of the exercise. In this study I have made use of a model of a musical culture in a society, created by Lundberg and Ternhag, based on the theory of cultural fields by Pierre Bourdieu. According to this model, the stature of a musical culture gives different forms of musical expression certain roles, but these roles can be remodelled, reflecting perhaps political or ideological influence.

This essay will discuss the Roman God Janus, as a figure of speech, in four different texts written by Publius Ovidius Naso, Michel de Montaigne, Francis Bacon and Elijah Fenton. The Janus figure could also illustrate the relationship between the past, the present and the future, because of the attributes of looking back and forward, in both space and time, that Janus was said to possess. Reinhard Koselleck's ideas of space of experience and horizon of expectation will be used as an analytical approach, thus creating a dual purpose for this essay. On one hand to understand texts about Janus, which implies an understanding of the changes over time associated with the history of ideas of Janus, and on the other the past's importance in relation to the future, which includes an understanding of Janus via Koselleck's thesis about the change in relationship between experience and expectation.The question formulations are as follows: How has the Janus motive changed over time in the researched texts? How can the literary use of Janus show the changed relationship between the space of experience and the horizon of expectation, and in a wider context between the past and the future? Janus has gone from being a physical presence, as the arcs of the Forum Romanum in ancient Rome, to becoming a tool for authors, one that spans many literary rooms.

Aim: The purpose of this study is to increase the knowledge around the location?s importance when rent setting office premises. Furthermore, I want to get broader knowledge about the real estate market as a whole when since it is of current interest.Method: The study is performed with the aid of qualitative interviews on persons with experience of office premises in Stockholm city. Theoretical dates mainly have been gathered via literature and the Internet. Then I have put together the interviews in order so that I finally can analyze empiric with theory.Result & conclusions: The results that have been achieved with this essay are how the concept location has been used within the real estate sector, also how important long-term thinking is when letting of premises, not only office premises.Suggestions for future research: Future studies can increase my study with more interviews, with for example real-estate owners.

The aim of this master?s thesis is to examine the discourses about Malmö public library that can be identified in several documents published by the library, articles, and various WebPages. Furthermore, our intention is to study the relation between the library?s identity, image and profile. The questions posed in the study are: Which identity discourses are Malmö public library giving expression for? What kind of conflicts between these discourses can we find? How is the identity, image and profile of the library in relation to one another? How does Malmö public library profile and market itself as a non-profit organization? Our theoretical and methodological building ground is in the discourse analytical field, with Enesto Laclau?s and Chantal Mouffe?s theories about discourse and society, as a starting-point.

Our everyday life is becoming more active and the activities we perform influence the way we dress. Due to an increase in activities undertaken in an urban environment, demands are changing and the need for active wear that meets the new demands follow suit. The four characters represented in the research can be seen as a reflection of the functional features needed, including base layer, mid layer/insulation and shell.Despite the increase in activities, most of our clothes are still constructed on static dummies or drafted on a table in 2D and the main developments within the active sportswear field is driven by material innovation. By creating garments on a body in movement, my aim is to develop new functions and expression in active sportswear through construction.Construction methods in active sportswear are examined and understood through observations and reconstructions and constitute the foundation of a study of movement for a design recovery.The movement and features required for leading an active urban life sets the direction of the development of new func- tional garments. A series of trial and error sessions and draping fabric on a live model in movement created the prototypes used in functionality tests to establish their feasibility.

Poly, to live in several loving and intimate relationships at the same time, is one alternative to the mono norm. In Sweden polygamy is illegal yet in recent years poly has slowly started to enter the hetero normative political agenda and raise debate in the media. But what does poly mean, and how do those who identify with this type of relationship describe it in contrast to mono? The theoretical framework is based on a structural viewpoint of the changes in the organisation of the family and the growing de-traditionalism of society. Amongst other I use a Foucauldian perspective to explain the structural shift (yet not replacement) between an Alliance pattern and a Sexuality pattern.

Denna kvalitativa studie behandlar matematiska uttryck hos förskolebarn. Syftet med studien är att undersöka och beskriva flickors och pojkars matematiska uttryck i förskolan samt vilka eventuella skillnader som kan iakttas i deras uttryckssätt. Detta mot bakgrund av att matematiken har fått ett allt större utrymme i förskolans verksamhet efter att förskolan fick sin första läroplan, Lpfö 98, med uttalade mål att sträva mot. Tidigare forskning visar att pedagoger bemöter flickor och pojkar olika i förskolan. Kan det ha att göra med att de uttrycker sig olika? Med detta som grund ville vi undersöka om det finns skillnader i flickors och pojkars matematiska uttryck.Matematik är ett språk och barn i förskolan utvecklar matematisk förståelse genom upplevelser i lek och sociala sammanhang.

Should libraries first and foremost be a source of free informationwhere the citizens can find whatever information they want, or dothe librarians have a responsibility for what kind of works theypresent to people on their shelves? A wild debate broke out inSwedish media in September 2012, after the artistic leader ofKulturhuset in Stockholm; Behrang Miri decided to weed out allthe Tintin albums from the children´s library Tiotretton. Hewanted to start a debate on stereotypes in children´s fiction, andwhat damage they do to children who face them. The purpose ofthe thesis is to carry out a discourse analysis of this media debate,and to identify the different views that are expressed on thedemocratic mission of the libraries, what media they shouldpresent. The method and theory is based on the discourse theory ofErnesto Laclau and Chantal Mouffe and their concepts are used toarrange the analysis around certain themes that build up twodifferent discourses; ?Freedom of information discourse? and the?Weeding out discourse?.The two main questions are: What views of the public librariesselection of works are expressed in the Tintin debate in Tiotretton,and how do the views relate to each other? What concepts arespecific for the debate, and what meanings do they get in thesedifferent views?In the concluding chapter I discuss which consequences theseopposing opinions can have for the future selection processes ofthe library..

The Swedish state and educational system are secular, so to say they do not depend on the former protestant state church anymore. Many people in Sweden are also secular. Even so, in school teachers meet students with a religious faith. The purpose of this study is to examine how teachers without a religious belonging experience the encounter with religious students. The method used was semistructured interviews with five teachers in a upper secondary school in a multicultural suburb of Stockholm.

This essay aims to explore the philosophical meaning of the expression ?present and real? in Clara ? or, On Nature?s Connection to the Spirit World by F. W. J. Schelling.

The governance and control of healthcare organizations has traditionally been run byprofessions inside the organization (Fölster et al., 2003). During the last decades Swedishhealthcare has undergone an institutional transformation where the governance has changedfrom professional governance to a more market like one (Sahlin-Andersson, 2006). Governingof healthcare can however be problematic as professional work is characterized by a highlevel of autonomy and tacit knowledge (cf. Tsoukas, 1997, Freidson, 2001). An expression ofthe new kind of governance is the annually published report ?Öppna jämförelser av hälso- ochsjukvårdens kvalitet och effektivitet?.

The aim of this study is to describe and analyze how the European union relates to the different dimensions of abortion. What kind of problem is abortion and whose right is it? Does difference framings of the problem enable different solutions?By analyzing debates from the European parliament through Carol Lee Bacchis method ?What?s the problem approach? I have come to see that different representations of a problem changes the problem it self. This emphasis that a problem is a problem in one context, but not in an other.Depending on the work of, among others, Barbara Hobson and Ailbhe Smyth I have focused upon the European union as a economical project, leaving social issues to national competence. This makes the EU a patriarchal project that fails to guarantee women?s rights.

The aim of this thesis is to investigate how purchasingmanagers in bookshops and public librarians reason withregards to their selection of fiction literature. Nineinterviews have been conducted in this qualitative studymade in the spring of 2013; four librarians, four bookmerchants, as well as a market director of a major chain ofbookstores. Our focus has been particularly directed toascertaining what influence the cultural-political mission oflibraries have had on the process of selection, as well as theextent to which factors such as demand and quality play apart in both organizations. We have been interested inseeing how libraries and bookstores compare with regards tothese factors, because of obvious differences in their goalsand purposes. Librarians see both the benefits and flaws intheir way of working, as well as in the way in whichbookstores conduct their business, and vice versa, that theyare often successful in cooperating, like when arrangingvisits from authors etc.