Fibroblast growth factors are signaling peptides that controls important cellular processes such as proliferation, differentiation, migration, adhesion and survival. Through binding to different types of receptors on the cell surface, these peptides can have different effect on the target cell. Which effect that is achieved depends on many factors. Thus, each of the 24 known FGFs different biological responses. The FGF receptors (FGFR 1-4) initiates different intracellular pathways which in turn leads to different biological responses.

Scrapie is an infectious neurologic disease in sheep caused by prions, corresponding to transmissible spongiform encephalopathies (TSEs) in other species. The prion is presumably constituted of PrPSc, the misfolded form of the normal endogenous prion protein, PrPC, which is found in practically all cells in the body. PrPSc can induce a conformational change in PrPC and misfold it as an imprint of itself; this is how prions amplify and spread. The process of conformational change is poorly understood and there might exist intermediate forms between PrPC and PrPSc. Bioassay using mice has traditionally been the golden standard in prion studies but is limited by cost and time.

This thesis focuses on the testing activities at the stages of development and change regardingintegration brokers. The study aimed to examine the overall challenges that exist regarding thetesting activities within this context, and the thoughts towards the development method testdrivendevelopment (TDD). TDD emphasizes high level of test coverage and where the testprocess is well integrated with the development process. To seek answers to our question weapplied qualitative interviews with companies and respondents to try to understand the globalchallenges that are related to this work and processes. The main conclusions presented in thisstudy is that the overall challenges are involving and educating project participants in the testingprocess activities and the contributory effect test have on the end product.

Servicescape is a research area within service management which processes the effect that the environment has on the service experience. The purpose of this essay is to find out how servicescape, with focus on the ?background music?, affects customer behavior in a clothing retail store. Through manipulation of the background music?s tempo the essay aim to explore to what extent this part of the servicescape a) affect the customers approach and avoidance behavior, b) is affected by customers with a hedonic or utilitarian shopping behavior, c) affects pleasure, arousal and dominance perceptions for the customer, and d) how the servicescape is perceived.Key words: Servicescape, approach-avoidance behaviour, pleasure, arousal, dominance, hedonic-utilitarian behaviour..

I have done a theoretical essay and to find out the answer to my questions I used literature study as my method. You can kind of say that I have used the literature as my empirical material, so my essay is in one way a qualitative study. I choose to have a social psychologist perspective to approach my questions. To answer the questions I have used a couple of researchers who a find relevant to answer my questions. I found Meads symbolic interactionism together with Goffmans theatremeatphor as an important theory to explain the social interaction.

In this work an assessment of the compressed air system in the facilities of Vattenfall Heat Uppsala has been conducted. The facilities constitutes, among others, a combined heat and power plant, and two waste incineration plants. The compressed air is supplied primarily by seven rotary screw compressors and yearly electric energy consumption in these has been determined. Furthermore, the usage of compressed air has been mapped in order to find processes with energy savings potential. Several suggestions how to reduce the usage of compressed air have been presented, resulting in decreased need of electric energy and reduced CO2-emissions.The results show that total need of electric energy in the compressors, during a standard production year, amounts to 5.83 GWh.

Denna rapport syftar till att utreda och klargöra de allmänna lämplighetsvillkoren vid fastighetsbildning (som finns beskrivna i 3 kap. 1 § fastighetsbildningslagen) och hur denna paragraf ska tolkas vid lämplighetsprövning.Detta har gjorts genom en rättsfallsstudie, där fokus lagts på hur paragrafen har tolkats i rättspraxis. Rättsfallsstudien har sedan kompletterats med propositionsanalyser och litteraturstudier. I uppsatsen har de 58 rättsfall som legat till grund för rättsfallsstudien redovisats för sig för att sedan analyseras och tolkas.Slutsatserna av arbetet presenteras i form av riktlinjer för vad som ska beaktas vid lämplighetsprövning. Riktlinjerna bygger på observerade tolkningar i rättspraxis och är menade att underlätta tolkningen av paragrafen.

Syftet med studien är att skapa förståelse för hur kvinnor på kvinnodominerade arbetsplatser upplever kritik. Studien kommer att vara en fältstudie vari man granskar kvinnor som är verksamma inom förskolan, då tidigare forskning visat på en klar majoritet av kvinnor inom denna yrkeskår.Avsikten med studien är inte att uppnå någon objektiv sanning av verkligheten, dock avser denna studie tolka eventuella fenomen som rör ämnet, samt skapa en förståelse för individens syn på begreppet.Informanterna har valts ut strategiskt, vidare präglas informanternas deltagande av självselektion. Man kommer inte att ta hänsyn till andra variabler än kön vad gäller urvalet.Teorier som studien vilar på är den symboliska interaktionismen där bland annat dess syn på rationalitet behandlas. Vidare tas Johan Asplunds teori om social responsivitet i beaktning och avslutningsvis Erving Goffmans teori om identitetsskapande.De slutsatser som kan dras i och med denna studie är att relationerna mellan individerna i en grupp verkar ha stor betydelse för hur man upplever kritik. För att undvika missförstånd kring det valda ämnet verkar allmän mening råda att "definitionen av situationen" är något man bör ta i beaktande, detta då kritik till en början upplevs som någonting negativt..

What psychologial processes are activated in experiencing mourning after a loss of a belovedperson? How is death described in other authors? novels and short stories compared to mine?This essay aims at analysing my two short stories The follower and The price for love fromdifferent aspects. I discuss the psychological realism and the spirituality using the method ofclose reading, interpreting and applying ideas of texts from other authors in my short stories.Death is a central phenomenon in both of my texts. Therefore I discuss death frompsychological and philosophical aspects in this essay. To get a philosophical frame of death Iturn to Jacques Derrida, Emmanuel Levinas and Martin Heidegger.

The Swedish production of biogas was 1,5 TWh 2011. About half of the production was used as vehicle fuels. The cost for upgrading biogas depends on the size of the biogas plant and its gas production. If the gas flow is low the cost will be high. However, further development of existing upgrading technologies or development of new ones, have good potential to decrease the upgrading cost for small scale biogas plants.

The purpose of this study has been to examine the unit manager?s perspective on making Lex Sarah-notifications. The study has been carries out by six semi structured interviews with persons in leading positions of the elderly from three different municipalities. They were asked about different circumstances that affects the problems with Lex Sarah. The results indicates that the unit manager?s act on elder abuse from the complex mechanisms that exist within the organization.

This study was built on the concept of Emotional Intelligence (EI) as an ability with four branches, to effectively: (1) perceive (2) reason (3) understand and (4) manage emotions. By closely studying the four processes of EI through eight semistructured interviews with psychologists, counselors, CBT-therapists and psychotherapists, a study of participants' stories from real practice was done and then analyzed and interpreted. The purpose of this study was to get the participants to describe and put words on practical experiences that occur with clients that correspond to the four domains that define the concept of EI according to Mayer et al. (2008) and find out about if their way of "doing" EI gets trained and developed after several years of professional activity. The results shows that the practitioners used all four branches of EI in dialog with the client, both intra- and interpersonal.

The study focuses on the use of poetry in language teaching in the lower grades in the Swedish school. Poetry has a reputation of being an art form with such specific rules and structures that children and teachers think that it is something that they do not have the ability to work with.  The purpose of this study is to get an understanding of how poetry is used in educating children. My research is based on the following questions. To which extent is poetry being used in schools and how is it being used?Can you as a teacher see any effects on childrens language development by using poetry?As a part of my study I have met with and interviewed four different people, who in one way or another is involved in teaching children. Two working teachers in the lower grades, one pedagogical resource and one artist that work with teachers in reaching different goals through the help of aesthetic processes.

This reportcommunicates the processes and results of my degree work in industrial design at candidate level at Umeå Institute of Design.During my degree work I had a cooperation with Svenska Jägareförbundet (Swedish Hunters Assosiation).The aim for my project has been to explore how I could make hunting a safer hobby and undertaking. Every year people get seriously injured and in average 2 people a year dies  due to hunting accidents. My goal is to identify problems within the hunters communication and approach. Through a creative design process I will find a valid  nd realistic solution to these problems. My project will be presented as a conceptual solution  hat will be based on currently existing technology.

Hammarby Sjöstad is a new district in southern Stockholm. A main objective with the Sjöstad project was to halve the environmental impact compared to other construction work. The environmental goals involve a halved water consumption rate, a local treatment of storm water and trials aiming to extract nutrients from the waste water. Sjöstadsverket is an experimental treatment plant used for testing new treatment processes for domestic waste water from Hammarby Sjöstad. The results are to be compared with the conventional process used at Henrikdals treatment plant today.