The aim of this master thesis was to examine a possible connection between chromatin functions and the DNA damage repair system, with the imprinted IGF2/H19 locus as a bait. Interactions can occur within and between chromosomes and it has been shown that H19 ICR on both alleles can communicate with alleles on other chromosomes. The methylation-sensitive insulator protein CTCF is bound on the maternal H19 ICR and acts as an insulator by blocking the IGF2 promoter to access its enhancers. This is possible by formation of loop structures by CTCF that enables intra and inter-chromosomal interactions. CTCF is poly(ADP-ribosyl)ated by PARP-1 when it is bound to H19 ICR.

This work is about the expanded conception of text and takes off in the use of this expression in the high school curriculum. The work begins with a theory chapter, where a few different definitions of text are the basis for reasoning about factors which can have contributed to an expansion of the conception. Hereby other important expressions, related to the expanded conception of text, as hypertext, multimedia and intermediality, are brought up. Further, is examined empirically how the expanded conception of text is interpreted, rhetorically and practically, by a few teachers in the High School. Finally, covered scientist?s theories are discussed and compared with the concluded empiric data.The study shows however, that the expanded conception of text in the curriculum has not become a conception for the teachers who were interviewed.

Det talas idag mycket om Sveriges satsningar på en skola för alla. Samtidigt mår många elever dåligt. Det är något som inte stämmer. Syftet med denna studie är att undersöka hur elevernas självbild påverkas av specialpedagogiskt stöd. Avsikten är att beskriva självbild, självkänsla och självförtroende, ur den enskilde elevens synvinkel.

The problem presented in this report is that of finding a method to calculate the lift force from a single-element airfoil of arbitrary shape. A number of restrictions are used in order to simplify calculations while retaining reasonable accuracy. The problem is solved for the two-dimensional case only and no finite-wing effects are taken into account. Furthermore, inviscid and incompressible flow is assumed. The method used to solve the problem is the vortex panel method, with vortex singularities distributed over simplified airfoil geometry.

In a complex and turbulent world, several companies begin to realize the value of information as a strategic resource and try to find strategies to manage this. This master thesis aims to describe the information management at Axis Communications AB. Axis is a fast growing company and due to this they have not been able to manage the flow of information whitin the company. To find out how the information was managed at this time we made a survey and employee interviews at three Axis business units. By analyzing the surveys and interviews we found several problems.

Avyttringen och ombildningen av kommunala och privata bostadshyresfastigheter till bostadsrättsföreningar har blivit ett allt vanligare fenomen under de senaste decennierna. Främst sker avyttringen i Stockholms kommun. Syftet med denna uppsats är att mäta om prissättningen vid utförsäljning av bostadshyresfastigheter inom Stockholms kommun skiljer sig beroende på om säljaren varit privat eller ett allmännyttigt kommunalt bolag. För att undersöka detta har olika regressionsmodeller applicerats på data över fastighetsprisregistret under två mandatperioder. Resultatet visar en tydlig prisskillnad mellan kommunala avyttringar och privata inom samma områdesindelning.

Communication, information and marketing are three of the main prerequisites for companies that want to increase their turnover. The everyday work for a Forest Manager within the forest owners? association Mellanskog consists to a large part of interpersonal communication, either by close vicinity contact or by phone calls. Interpersonal communication is time consuming and resource intensive. If the flow of information, communication and marketing does not function well then there is a lack of a base for development.

This project started when LIC Audio AB wanted help with development of a hearing aid for public rooms. The problem is that a lot of people suffer from some sort of hearing impairment. In places with a lot of people and background noise the problem becomes bigger and the sound seems to flow together. During the project we found the solution for the problem in the shape of a headphone. The headphone receives a signal from a preinstalled hearing loop.

Syftet med denna studie är att titta på det vi vet om dopamins roll i aptitreglering idag, både generellt och med ett veterinärmedicinskt intresse specifikt på hund. Dopamin är transmittorsubstans i flera nervbanor i hjärnan och dess frisättning har traditionellt kopplats starkt till att positivt förstärka nyttosamma upplevelser eller handlingar i det som kallas kroppens ?belöningssystem?. I relation till föda och födorelaterade beteenden har man dock på senare tid sett att dopamin har en bredare betydelse än att enbart förstärka själva födointaget. I litteraturen syns därför ett fokusskifte mot ett vidare perspektiv med hänsyn till dopamins alla, nu kända roller ? något som väckt insikten om det dopaminerga systemets komplexitet och frågan om det ens är möjligt att få en helhetsbild över alla dess funktioner. Denna litteraturstudie har undersökt delar av ett stort litteraturmaterial fram tills idag och konkluderar att trots mycket forskning är dopamins exakta funktioner i aptitregleringen fortfarande inte klarlagda utan det verkar fortfarande råda ovisshet och oenigheter.

AbstractA master thesis in business administration 30 hp, Jönköping International Business School, Spring semester 2012.Authors: Sarah Henningsson & Jim BörefeltSupervisor: Urban ÖsterlundTitle: Commercial real estate investment ? Factors from an investor perspectiveBackground and problem: In this study, we focused on the real estate investor and the factors and issues that may arise and affect real estate investment decisions. It has been put in relation to the other parties in the process of assessing and affecting real estate investment decision. The parties that we studied are real estate investors, banks, brokers and appraisers.Purpose: This study aims to describe and explain the factors that affect commercial real estate investments for investors, credit assessment conducted by the bank and valuation made by the broker and appraiser.Delimitations: We have chosen to limit the study to commercial real estates including residential, retail and office properties, industrial properties and combinations thereof. Agriculture buildings and forestry plots are not examined.

The purpose of this article is to explore the technologies of government that are created within gender disorder assessments as an institution. I have done so by utilizing Norman Faircloughs discourse analysing instrument ?communicative action?, which focus on the social institution as relational.The material is strategically chosen by gathering texts from the Swedish state, the psychiatric clinics, NGO:s and by performing interviews with transsexual patients.When analysing the communication of the main agents, I have concluded that practices highly are a result of repeating text and speech inside the institution. The psychiatric assessments can also be seen as an illustration in changes in how citizens are governed in advanced liberal societies, where the role of the state has been gradually reduced in favour of other agents.I consider that the change illustrates an ?acting at a distance?-mentality where the patient is introduced to participate in the definition of the care in what I call ?negotiation as a technology?.

As of 2013, around 51 million people were living on the run, classified as refugees. One of the reasons the number has increased so much during the last years can be explained by the war in Syria. The aim of following study is to evaluate the impact the Syrian refugee flow has had on the Turkish society up until today, seeing the consequences of economic, political and social impact made on the Turkish society. Due to these chosen aspects the study will be concentrated only on the changes in the Turkish society brought about accordance with economic, political and social effects. What is desirable is to achieve greater understanding of the positive and negative aspects of refugee flows on host countries.

Intelligent IT-based solutions, often called Smart Grids, are considered to be the future balancers of renewable energy sources. One area within the Smart Grid concept is called demand response, which is focused on making customers more consumption flexible by making them more active in their consumption. In this thesis the aim is to analyze a business model by investigating the income potential for a demand response solution as well as its market potential. This has been done through literature studies, interviews and development of a computational model.The use of 5000 households with flexible consumption can provide a cost reduction of 17.2% or 2.4 million SEK for a balance responsible party during an average year. If the solution is used to make strategic bids on the regulation markets the study indicates that the largest potential for revenues lies within this strategy.

The aim of this thesis is to describe how service companies through adjustment of the customer?s zone of tolerance can influence customer?s perception of the service during the processes of service delivery and create customer satisfaction. The method used was case study approach utilizing personal interviews, which were conducted at two service companies. The study showed that the aspects of the service that have greatest importance for the customer?s assessment of the service and customer satisfaction among others are personal treatment and that personel behave in the way that makes the customer feel itself taken good care of and unique.

Today evidence exist that environmental chemicals deteriorate male sperm quality and that testicular cancer is increasing. Bisphenol A (BPA) is a chemical with estrogenic effects used in the manufacture of polycarbonate plastic and are found in, for instance, plastic boxes, feeding bottles and food containers. Much of the research on how men's reproductive ability is influenced are performed on rats. This review article complies how male rat reproduction is affected by BPA as a model for humans. Studies have investigated how sperm are affected, hormonal changes during reproduction and how reactive oxygen species (ROS) affects sperm.