The purpose of this literature review was to describe the paths of exposure and accumulation of organic pollutants into the tissues of farm animals. Organic pollutants can be spread in the environment by air and rainwater. Farm animals can be exposed to these pollutants for example by eating soil or contaminated plants. Many of the pollutants can then accumulate in the fat tissues of the body because of their lipophilic character. Brominated flame retardants and perfluorolated compounds are both pollutants of current interest.

Phytoestrogens are secondary metabolites produced by plants. Among the plants that make phytoestrogens are soya, red clover and some types of grass. The name phytoestrogen is a collective term for compounds such as genistein, daidzein, biochanin A and formononetin. These compounds are similar to oestradiol-17? in their chemical structure.

A renewed application for environmental permit for the Hovgården landfill in Uppsala shall be submitted before December 2004, therefore the municipality of Uppsala needs improved knowledge of the contents, mostly organic compounds in the leachate and they also want to find a method to minimize the emissions of these compounds. The purpose of this study was to find a practical and economical method based on chemical oxidation using oxidants. The oxidants investigated are Fenton's reagent, hydrogen peroxide, Oxypro, potassium permanganate and potassium persulfate. The study was made on untreated leachate and leachate that has been treated in an aerated dam followed by sedimentation dams collected from the Hovgården landfill, and alson on sludge water from sludge storage cells. The effects of the five oxidants have been established by analysing the UV absorbance at the wavelengths 253,7 nm and 260,0 nm at different pH values. The UV absorbance was used to indicate the amount of aromatic hydrocarbons in the water. Also analyses of iron and manganese were done after the experiments with potassium permanganate, hydrogen peroxide and Fenton's reagent.

The process of drug discovery is very slow and expensive. There is a need for reliable in silico methods; however the performance of these methods differs.This work presents a targeted study on how the drug discovery methods used in OpenEye?s tools ROCS, EON and FRED perform on targets with small ligands. It was examined if 12 compounds (markers) somewhat similar to AMP could be detected by ROCS in a random data set comprised of 1000 compounds. It was also examined if EON could find any electrostatic similarities between the queries and the markers.

Introduction The genetic skin disease epidermolytic ichtyosis is caused by mutations in either keratin gene 1 or 10 and leads to blisters and hyperkeratosis of the epidermis. At cellular level the disease is seen as aggregates in the keratin filaments. Since medicines are hard to investigate and produce mainly due to lack of reproducible model systems, there is no good treatment available for this disease today. In this article we describe how an in vitro model consisting of cells from a stable cell line transfected with expression plasmids to mimic patient cells, may be a possible alternative for screening compounds for therapies. The first step was to generate an expression plasmid required to complete the in vitro model.

Oilseed rape crops are an important in southern Sweden because of the high intensity of wheat growing. Pollen beetles are the most important pest in oilseed rape and causes often economic losses. Therefore it?s of great importance that we can control the population density, e g by using insecticides if necessary, to avoid mayor yield losses. In year 2000 pollen beetles were numerous in the province of Östergötland. The farmers sprayed with insecticides several times, but with low effects on the beetles. Field trials and laboratory experiments showed that pollen beetles had developed resistance against pyrethroids.

The purpose of this study is to give an overview about iron fortification from the view of technique and health. Example of a technical aspect is different iron compounds which are used for fortification like ferrous sulfate, ferrous fumarate and elemental iron. In the aspect of health the big question is if iron fortification can improve the health in reducing the prevalence of anemia. The study focuses on flour fortification with iron in Egypt and Iran and involves a literature study with scientific articles. Also information from WHO (World Health Organization), FAO (Food and Agriculture Organization) and FFI (Flour Fortification Initiative) are used.Fortification means an intentionally increasing of the content of micronutrient in foods with the aim to improve the food quality and deliver a nutritional benefit to the consumer.

The search for antibiotic compounds from the natural environment has been going on for seven decades, ever since penicillin entered the market and antibiotic treatments became routine. The evolutionary pressure put on the pathogenic microorganisms induced a rapid spreading of naturally occurring resistance genes, leaving only the option of finding new antibiotics to treat the resistant pathogens. Microorganisms have been extensively mined for their biosynthetic abilities to produce biologically active compounds. To date, more than 23 000 microbial natural products have been discovered. The Actinomycetales are ubiquitous bacteria that have been used for antibiotic discovery for more than half a century, and over 10 000 natural products have been identified from the order.

Aim: The purpose of this work is to investigate what differences there are between a credit union that is connected to Sweden?s Credit Association and an independent association, and how these differences have affected the union?s success. Method: A qualitative study has been made by means of email and telephone interviews. Respondents were chosen from Sweden?s Credit Association, Credit Guarantee Association in Gävleborg and Övre Norrland Guarantee Association. The interviews were then analyzed in the light of our theoretical studies. Result and conclusions: We have found that there are three major differences between the unions.

In the fluidized bed furnace at Rönnskärsverken, Skelleftehamn, sulphur-containing ore concentrates are roasted in order to remove about 50% of the sulphur in the incoming ore concentrate. This occurs in order to reach the goal of a matte containing 55% of copper in the following smelting process. At the same time as the ore concentrate is partially roasted pollutions as arsenic, antimony and bismuth are expelled. Earlier made thermodynamic calculations of equilibrium suggested that calcium and magnesium form stable compounds with arsenic and thereby inhibit expellation of arsenic in the fluidized bed furnace, an element that is undesired. The purpose of this thesis work was to gain knowledge of the mechanisms behind the formation of these stable arsenic compounds.

In this project a LC-MS-method for the analysis of gamma-hydroxybutyrate, gamma-butyrolactone, 1,4-butanediol, amphetamine and methadone was developed.Initially, the efficiency of the ionisation of the analytes was evaluated with respect to the ionisation technique (ESI, APCI and APPI) and the composition of the mobile phase. In the next step a number of different columns was tested in order to find the one with the greatest potential for separation of the substances in question. Using the selected column, the separation was optimised by means of experimental design and the software The Unscrambler 7.8. The parameters studied were the flow rate, the column temperature and the mobile phase composition. The response variables were the resolution between the target compounds and the retention time of the last eluting compound.These experiments showed that, in order to obtain the best ionisation, the mobile phase should consist of 5 mM formic acid in water and acetonitrile.

In Sweden more than 400 000 private households have not yet sufficient wastewater purification. These effluent is considered as an increasing problem and many onsite purification methods have been studied. In this investigation, the method of reactive bed filters have been tested by column and batch experiments. Five different kinds of filter materials with reactive surfaces have been studied concerning their capacity to absorb ammonium and phosphorus from wastewater. The materials that were examined are Filtra N, wollastonite Filtra P, blast furnace slag and Polonite®.

There are around 855 000 on-site sewage systems in Sweden and some 1 800 of these are located in the municipality of Sigtuna. The Sigtuna local authority has set the goal that all sewage systems with insufficient function should be improved before the end of year 2010. A malfunctioning on-site sewage system may cause three main problems: spreading of diseases, discharge of eutrophicating compounds and wastage of resources. The municipality strives to reduce these problems already at the stage of granting permits for installation of on site sanitation systems. The municipality has recently adopted new guidelines, which demands certain minimum reductions for different compounds. The guidelines also state that it is preferred that neighboring house-owners cooperate in jointly built and operated sewage systems and that the system should be able to recycle plant nutrients.

The aim of this thesis is benchmarking of the program, based on dynamic programming, that earlier was written to imitate the production planning at TSS.This thesis starts with a chapter about the construction of the DP-program, a shorter description of one and each of the program parts and also a list over the in- and output data in each program part. The DP-program consists of six linked MATLAB-files that together produce an optimized production plan for the different planning groups at TSS. The program reads in and reformat the given data and optimize the production of the articles in one group. Finally it compounds all article production plans and give us a production alternative.After running the program with new data the result shows, resembling with previous results, that TSS could be able to make some distinct cost-savings. According to the program, a 50 % decrease of TSS production costs is possible. .

Denna studie har skrivits för att skapa en förståelse för vad deltagande i handikappidrott betyder för skapandet av identitet och självbild påverkas hos personer med intellektuellt funktionshinder. Att genom idrott lära sig vem jag är och vad jag kan. Ett ämne som är viktigt att belysa i en samhällsgrupp som ofta känner sig orättvist bedömda av andra. Det är även en samhällsgrupp som är eftersatt inom den kvalitativa forskningen och idrottspedagogiken. För att studera detta användes deltagande observationer och intervjuer.