Rotavirus causes diarrhea in young mammals all over the world, including infant humans. The diarrhea leads to severe dehydration that can be fatal if left untreated. The dehydration can be treated with fluid therapy and the infection heals itself. Despite the relatively easy treatment half a million children under the age of five dies every year due to diarrhea caused by rotavirus. Rotavirus sorts into the family Reoviridae and is a double-stranded RNA virus with a segmented genome.

Rotavirus causes diarrhea in young mammals all over the world, including infant humans. The diarrhea leads to severe dehydration that can be fatal if left untreated. The dehydration can be treated with fluid therapy and the infection heals itself. Despite the relatively easy treatment half a million children under the age of five dies every year due to diarrhea caused by rotavirus. Rotavirus sorts into the family Reoviridae and is a double-stranded RNA virus with a segmented genome.

Background: The incidence of caesarean section for breech presentation has reached approximately 90 % in Sweden. In many of these cases, by means of specific selection criteria, it would be as safe to plan for vaginal breech delivery. Aim: The objective of this study was to investigate differences in management and to compare maternal and fetal outcomes according to delivery mode of breech presentation; vaginal vs. caesarian section. The study included breech presentation in full term singleton pregnancies at the UppsalaUniversityHospital, Uppsala, Sweden (UAS). Method: The study was based on medical record data with a retrospective, descriptive, comparative design with quantitative approach. The method for data collection was a manual review of patient records using a structured questionnaire. Results: Of the women with children in breech presentation during the period studied, 11 % gave birth vaginally.

Feline infectious peritonitis (FIP) is a feline viral disease with high mortality. There is no cure or any effective vaccine available today. Many questions are yet to be answered about this disease and the immune response in affected cats. The aim of the study is to evaluate two different techniques for the study of cytokine profiles in cats vaccinated with a vaccine concept against FIPV. More information about the immune response in these cats could give valuable information to better understand the pathogenesis of the disease and the development of an effective vaccine.

Laminitis is a debilitating disease causing much suffering to horses and ponies all over the world. It is manifested in the hooves as a mechanical failure of the suspensory apparatus between the hoof capsule and the distal phalanx. Due to the weight of the horse the disease may result in a dislocation of third phalanx. Six healthy standardbred trotters were used in this study on whether standardbreds tolerate forced recumbency as well as Shetland ponies. Recumbency was induced pharmacologically but maintained only by lowering the ceiling height of the box to a height of approximately 125 ? 140 % of the horse´s thoracic height.

Every spring you can see newborn foals running on fields among the mare. But some unfortunate end up visiting the equine hospital requiring surgery. This is a challenge for the anesthetist because of the neonatal foal?s unique physiology. Therefore you need to take these differences under consideration when you anesthetize foals.

Apart from recognizing and neutralizing threats, antibodies also have the ability to regulate immune responses against their specific antigen. IgG administered together with erythrocytes is well known to induce >99% suppression. This has been used to prevent haemolytic disease in new-borns since the 1960's, but the mechanism behind it is still not completely understood. The effect on the primary response is well established, but its influence on induction of immunological memory is still heavily debated. In this study adoptive cell transfer of splenocytes to irradiated mice was used to survey the effect IgG has on induction of immunological memory without disturbance from the primary IgG response.

Det saknas idag metoder för att med säkerhet fastställa diagnosen Bornasjuka intra vitum. För att få en så säker diagnos som möjligt krävs fortfarande histopatologiska belägg och påvisande av virus i material från centrala nervsystemet, vilket ej kan tas från levande djur. Trots det finns det en risk att det intracellulära viruset undgår detektion då infekterade celler ej är jämt fördelade i hjärnan. De kliniska symtomen är specifika enbart för infektion i centrala nervsystemet och inte för Bornasjuka. Att förlita sig på antikroppar är osäkert på grund av låg titer som kan göra testen mindre tillförlitliga.

Bovine milk is an excellent source of bioactive peptides. The bioactive peptides are in an inactive state in the protein and are released during enzymatic activity, e.g. during cheese ripening. Specific properties of bioactive peptides from ripened cheese has been reported, e.g. antihypertensive, antioxidative, antimicrobial, immunomodulatory and mineral binding.

Title: Are we born gifted or can we learn and teach our children to be musically interested? The aim of this study is to evaluate how we influence the development of musicality in children. The study included 30 persons divided into three groups (ten members in each group). Group 1 consisted of pregnant women. Group 2 consisted of parents of babies age 0 to 1 year old and group 3 teenage parents.

I denna studie har förekomst av progesteronreceptorer i olika typer av primära juvertumörer undersökts med hjälp av immunohistokemi. Dessutom har tumörceller från carcinomcellinjen CMT-U27 odlats i olika cellodlingsmedium och exponerats för olika testsubstanser som binder till progesteronreceptorn (progesteron och RU486/mifepristone). Cellernas receptoruttryck och progesteroninnehåll utvärderades med hjälp av ELISA och tumörcellernas viabilitet analyserades med Colorimetric Cell Viability Test. Av resultaten framgår att samtliga undersökta primära juvertumörer uttryckte progesteronreceptorer. De odlade cellerna hade högre cellviabilitet när de odlades utan fetalt bovint serum (FBS). Efter exponering med progesteron minskade tumörcellernas uttryck av progesteronreceptorer, vilket hämmades av mifepristone.

The genus Borrelia is a widespread, pathogenic pest and the causative of among others borreliosis or Lyme disease. The vector for the bacteria is the hard tick, Ixodes ricinus and the infection is transferred through a bite. Untreated, Borrelia may cause arthritis, heart damage or neuroborreliosis. Infection is made possible through different strategies for avoiding the body?s complement system.

Bakgrund:Den dominerande cancerformen hos män över 75 år är prostatacancer. Kosten har en påverkan på många sjukdomstillstånd och på senare tid har man undersökt misstankarna kring om höga nivåer av IGF-1 kan öka risken för att utveckla prostatacancer. IGF-1 finns naturligt i kroppen men hormonet finns bland annat också i vissa livsmedel så som mejeriprodukter. Syfte:Att granska tillgänglig evidens gällande samband mellan höga nivåer av IGF-1 och prostatacancer, samt att om ett samband går att finna, undersöka om en kostrekommendation kan göras för att sänka nivåerna av detta hormon i kroppen och på så vis minska risken för utveckling av prostatacancer. Metod:Systematisk litteraturstudie.

African swine fever, ASF, was first described 1921, in Kenya. The virus has thereafter spread through many African countries as well as in Europe, Asia, South- and Central America. The virus is spread via three different cycles, of which one is sylvatic and includes warthogs and soft ticks. The other two are between domestic pigs and the one most common one is caused by humans, who not always realize the seriousness of precautions. The infection manifests as hemorrhagic fever, but can also be more or less unnoticed. The aim of this study was to use molecular tools to detect and partly genetically characterize ASFV both in soft ticks and in serum from domestic pigs in Uganda. Comparing viruses detected in ticks with those detected in domestic pigs I also wanted to investigate possible links between the sylvatic and domestic cycle.

?Tollarsjuka? is a disease with a suspected immunopathological background seen in Nova Scotia duck tolling retrievers. Pyrexia, lameness, stiffness and joint- or musclepain are typical clinical signs. The purpose of this study is to describe case histories from dogs with a possible evidence of ?tollarsjuka?. 18 private dogs were included in this report. Generalised stiffness, lameness and fatigue were the most frequent manifestations of the disease.