The aim of this master thesis was to examine a possible connection between chromatin functions and the DNA damage repair system, with the imprinted IGF2/H19 locus as a bait. Interactions can occur within and between chromosomes and it has been shown that H19 ICR on both alleles can communicate with alleles on other chromosomes. The methylation-sensitive insulator protein CTCF is bound on the maternal H19 ICR and acts as an insulator by blocking the IGF2 promoter to access its enhancers. This is possible by formation of loop structures by CTCF that enables intra and inter-chromosomal interactions. CTCF is poly(ADP-ribosyl)ated by PARP-1 when it is bound to H19 ICR.

Avyttringen och ombildningen av kommunala och privata bostadshyresfastigheter till bostadsrättsföreningar har blivit ett allt vanligare fenomen under de senaste decennierna. Främst sker avyttringen i Stockholms kommun. Syftet med denna uppsats är att mäta om prissättningen vid utförsäljning av bostadshyresfastigheter inom Stockholms kommun skiljer sig beroende på om säljaren varit privat eller ett allmännyttigt kommunalt bolag. För att undersöka detta har olika regressionsmodeller applicerats på data över fastighetsprisregistret under två mandatperioder. Resultatet visar en tydlig prisskillnad mellan kommunala avyttringar och privata inom samma områdesindelning.

With the increasing costs in concentrate the importance in producing ensilage with a high quality is becoming more and more important. To succeed with this goal it is of importance not only to harvest in the right period, but also to be able to store the ensilage without a decrease in quality and nutrional values. To maintain a good ensilage the covering of the ensilage must be carefully made. An unsuccessful covering causes mould to grow in the ensilage, which both increases the work load and also increases the amount of feed which is wasted. A bigger amount of spoiled feed also increases the risk of feeding spoiled feed to the cattle.

The purpose of this article is to explore the technologies of government that are created within gender disorder assessments as an institution. I have done so by utilizing Norman Faircloughs discourse analysing instrument ?communicative action?, which focus on the social institution as relational.The material is strategically chosen by gathering texts from the Swedish state, the psychiatric clinics, NGO:s and by performing interviews with transsexual patients.When analysing the communication of the main agents, I have concluded that practices highly are a result of repeating text and speech inside the institution. The psychiatric assessments can also be seen as an illustration in changes in how citizens are governed in advanced liberal societies, where the role of the state has been gradually reduced in favour of other agents.I consider that the change illustrates an ?acting at a distance?-mentality where the patient is introduced to participate in the definition of the care in what I call ?negotiation as a technology?.

The objective of this thesis was to get more knowledge about how to design a dairy farm reducing the working hours and the work tasks whit high work load. I will try to reduce the working hours and the tasks whit high work load on my own farm witch I am about inherit. Today, the old stanchion barn has room for about 60 cows and 74 young cattle and need two men to run it every day. The total acre is 188 hectare, 100 hectare forest, 65 hectare farmlands and 23 hectare natural pasture. I have studied two solutions. In the first solution, I will use my old barn for young cattle and build a new barn for the cows.

Today a trend can be seen towards fewer dairy farms and increasing number of cows per farm. Larger farms set a higher demand of more labour efficient milking systems. The time to enter and exit milking rotary platforms is crucial to maintain a high cow throughput. This study is a project initiated by DeLaval in order to evaluate the cow throughput and cow behaviour during entry and exit in two types of parallel external rotaries with different bail designs. The two rotaries compared were DeLaval parallel rotary PR2100 and PR3100HD.

Intelligent IT-based solutions, often called Smart Grids, are considered to be the future balancers of renewable energy sources. One area within the Smart Grid concept is called demand response, which is focused on making customers more consumption flexible by making them more active in their consumption. In this thesis the aim is to analyze a business model by investigating the income potential for a demand response solution as well as its market potential. This has been done through literature studies, interviews and development of a computational model.The use of 5000 households with flexible consumption can provide a cost reduction of 17.2% or 2.4 million SEK for a balance responsible party during an average year. If the solution is used to make strategic bids on the regulation markets the study indicates that the largest potential for revenues lies within this strategy.

The purpose of the study is to examine what effects the law has on principals? approaches to mandatory reporting of child maltreatment (Social Services Act 14:1§). Moreover, the aim is to study if the regulation gets the impact intended. To respond to the purpose, legal science methods in the form of sociology of law were employed aided by qualitative semi-structured research interviews. The interviews comprised six principals in six different schools in the Stockholm area.

Regulation of rivers by dams and reservoirs is a good example where anthropogenic impact could be considerable both in the local environment, but also has major implications upstream and downstream. This study was accomplished as a literature study of the river Nile, which is extremely important for water supply. The purpose of this study was to investigate the consequences of the construction of the Aswan High Dam, to obtain a consistent flow for water supply, irrigation and power generation in Egypt. Since Egypt has a very hot and dry climate large amounts of water in reservoir is lost to the Nubian aquifer system and by evaporation. The consequences from constructing the dam are considerable.

This thesis investigates the regulation of hybrid work environments by focusing on the implementation of rules by both management and employees. It examines the methods used to measure compliance and the consequences of non-compliance within organizations. The study also explores how flexibility in work arrangements and the balance between work and personal life affect employee well-being and productivity. Furthermore, it highlights the critical role of self-leadership in navigating the complexities of hybrid work, emphasizing how effective self-management can enhance organizational efficiency and employee satisfaction. We have adopted a qualitative research approach and interviewed employees, managers, and HR personnel with experience in hybrid work. The different perspectives are expected to provide insights into this area by including all levels within an organization It is evident that organizations that have clearly established rules and guidelines regarding hybrid work have achieved the best desired results.

Automatic trimmerhead is an examination project for making an automatic trimmerhead for grass trimmers with the user and functionality in focus. Our perception is that a happy user is a user who can pick up his or her trimmer, use it and put it back to its place when the job is done. It should not be necessary to interrupt work and perform maintenance on the machine just to make it work as promised.The project has been made in collaboration with the company Husqvarna, which is one of the biggest actors dealing with garden machinery on the market. Together we determined the project goal, ?To invent, construct and test a brand new concept for how an automatic trimmerhead can look and function?.At this day there are several different automatic trimmerheads on the market, both semi and fully automatic.

Forskning har sedan länge visat att oro dämpar upplevelsen av känslor och fysiologiskt påslag, men inte varför vissa personer har större behov av att dämpa sina känslor än andra. Nyare teorier om Generaliserat ångestsyndrom (GAD) indikerar att det är svårigheter med känsloreglering som är kännetecknande för diagnosen, då personer med GAD i högre grad än andra antas uppleva sina känslor som aversiva, och oro blir ett symptom på detta. Studien bekräftar en stark koppling mellan oro och svårigheter med känsloreglering i en studentpopulation , mätt med hjälp av tre självskattningsformulär, där det framkommer att ju större svårigheter med känsloreglering en person har, desto mer oroar sig denne. Den specifika känsloregleringssvårighet som i studien har störst koppling till oro och GAD är ?bristande strategier att handskas med känslorna?.

The high feeding value of red clover makes it into an important species in Swedish agriculture. There are three different maturity types grown in Sweden, early, medium late and late. The time for heading, regrowth and winter hardiness is affected by the maturity type, but there can also be other factors that are affected by the maturity type, for instance fiber content. In a greenhouse experiment three red clover varieties of different maturity types were compared; early Titus, middle late SW Nancy and late SW Torun. The features compared were fiber content and differences in development rates.

Syftet var att beskriva omvårdnaden kring nyfödda barns tillmatning på svenska BB-avdelningar, om föreskrifter följdes och om hänsyn togs till eventuell allergihereditet. Metod: Deskriptiv tvärsnittsstudie med kvantitativ ansats Resultat: Av alla nyfödda barn vid 26 barnkliniker i Sverige vecka 26 år 2009 (n=849) tillmatades 18 % . Moderns bröstmjölk gavs till 16% medan 78 % tillmatades med komjölksbaserad modersmjölksersättning. Den vanligaste orsaken till tillmatning av ersättning var att mammans egen mjölkproduktion inte hade kommit igång (24 %). Andra vanligt förekommande anledningar till tillmatning var lågt blodsocker (18 %) samt sugproblem hos barnen (16 %).

Denna studie undersökte om det fanns ett positivt samband mellan transformellt ledarskap och autonom motivation samt medierande effekter på, autonomi, relaterande och kompetens (Deci & Gagné, 2005). 104 personer har deltagit i studien, 54 kommer från en kyrka i Norra Sverige och 49 kommer från ett försäkringsbolag. 67 (64.4 %) av deltagarna är män och 37 (35.6 %) kvinnor. Det transformella ledarskapet mättes genom instrumentet (TLI) Transformellt Ledarskaps Inventorium (Tjärnberg, 2007). Den autonoma motivationen mättes genom en anpassad variant av (SRQ) Self Regulation Questionnare (Ryan & Connell, 1989).