Stabilization of subgrade is an internationally common technique to improve the characteristics of a soft soil. Improving the stiffness and bearing capacity of the subgrade enables the pavement to be designed with reduced depths of subbase and basecourse aggregates. This makes the stabilization technique both economically and environmentally interesting. Both natural and stabilized soils have high inherent property variability that should be considered when the characteristic value is derived. By analyzing the spatial variability in stabilized and natural subgrades it is possible get the parameters needed for reliability?based modeling of soil properties.

Målet med Brunnsviken Brief Quality of Life Inventory (BBQ) är att skapa en kortfattad och lättadministrerad skattningsskala för självupplevd livskvalitet med goda psykometriska egenskaper vilken är gratis för alla att använda. I framtagningen av BBQ har data insamlad med Quality of Life Inventory (QOLI) i tidigare studier använts för att identifiera de livsområden med störst betydelse för självupplevd livskvalitet. I aktuell studie har normvärden tagits fram för den i studien ingående undersökningsgruppen bestående av 167 psykologistudenter. Studien har visat att BBQ har utmärkt reliabilitet (test-retest), 0,89. Vidare hade BBQ lika god validitet för undersökningsgruppen som QOLI.

Tidigare studier har visat att bristen på strukturell empowerment på vårdavdelning ofta leder till försämrad personalhälsa, sämre arbetsmiljö och mindre samarbete med kollegor samt högre grad av utmattningssymtom. Syftet med studien var att beskriva vårdpersonalens upplevelse av strukturell empowerment vid en akut kirurg- och ortopedavdelning, samt att undersöka om det finns några skillnader mellan sjuksköterskors och undersköterskors skattning av strukturell empowerment. Ytterligare ett syfte var att beskriva vårdpersonalens upplevelse av arbetstillfredsställelse samt att reliabilitetstesta ett instrument som mäter strukturell empowerment. Data gällande strukturell empowerment samlades in med instrumentet Condition of Work Effectiveness Questionnaire (CWEQ och CWEQ II) och data gällande arbetstillfredsställelse samlades in med en studiespecifik fråga. Femtioen enkäter delades ut, 43 personer svarade vid första mätningen och 39 personer vid andra mätningen.

Duchenne Muscular Dystrophy (DMD) is a hereditary X-linked fatal disease that affects 1 in 3500 male births. It is the most common kind of muscular dystrophy in children and leads to death in the late teens or early 20s for many patients. The mdx mouse is a model of DMD that can be used to investigate experimental therapies. Overexpression of a glycosyltransferase, CT GalNAc, in mdx mice has been demonstrated to prevent the development of muscular dystrophy. Overexpression of another glycosyltransferase, LARGE, is currently being investigated as a treatment for another group of muscular dystrophies, the dystroglycanopathies. In this study, we overexpressed LARGE in mdx mice in order to investigate its effect on the development of muscular dystrophy.

The ability to tackle NP-hard problems has been greatly extended by the introduction of Metaheuristics (see Blum & Roli (2003)) for a summary of most Metaheuristics, general problem-independent optimisation algorithms extending the hill-climbing local search approach to escape local minima. One of these algorithms is Iterated Local Search (ILS) (Lourenco et al., 2002; Stützle, 1999a, p. 25ff), a recent easy to implement but powerful algorithm with results comparable or superior to other state-of-the-art methods for many combinatorial optimisation problems, among them the Traveling Salesman (TSP) and Quadratic Assignment Problem (QAP). ILS iteratively samples local minima by modifying the current local minimum and restartinga local search porcedure on this modified solution. This thesis will show how ILS can be implemented for MSA.

The ability to tackle NP-hard problems has been greatly extended by the introduction of Metaheuristics (see Blum & Roli (2003)) for a summary of most Metaheuristics, general problem-independent optimisation algorithms extending the hill-climbing local search approach to escape local minima. One of these algorithms is Iterated Local Search (ILS) (Lourenco et al., 2002; Stützle, 1999a, p. 25ff), a recent easy to implement but powerful algorithm with results comparable or superior to other state-of-the-art methods for many combinatorial optimisation problems, among them the Traveling Salesman (TSP) and Quadratic Assignment Problem (QAP). ILS iteratively samples local minima by modifying the current local minimum and restartinga local search porcedure on this modified solution. This thesis will show how ILS can be implemented for MSA.

The present study aims to investigate the phonological development of typically developing monolingual Swedish speaking children aged three to four years. The result could be used in the standardization of a new phonological test material for clinical speech and language pathology assessments. One-hundred and thirty four children aged three and four years (73 girls and 61 boys) were assessed with the new material. The children were tested in kindergartens in three communities in southeastern Sweden. Their assessments were audio recorded, transcribed phonetically and analyzed with Percentage Phonemes Correct (PPC) and Percentage of Words Correct (PWC).

The ability to tackle NP-hard problems has been greatly extended by the introduction of Metaheuristics (see Blum & Roli (2003)) for a summary of most Metaheuristics, general problem-independent optimisation algorithms extending the hill-climbing local search approach to escape local minima. One of these algorithms is Iterated Local Search (ILS) (Lourenco et al., 2002; Stützle, 1999a, p. 25ff), a recent easy to implement but powerful algorithm with results comparable or superior to other state-of-the-art methods for many combinatorial optimisation problems, among them the Traveling Salesman (TSP) and Quadratic Assignment Problem (QAP). ILS iteratively samples local minima by modifying the current local minimum and restartinga local search porcedure on this modified solution. This thesis will show how ILS can be implemented for MSA.

The ability to tackle NP-hard problems has been greatly extended by the introduction of Metaheuristics (see Blum & Roli (2003)) for a summary of most Metaheuristics, general problem-independent optimisation algorithms extending the hill-climbing local search approach to escape local minima. One of these algorithms is Iterated Local Search (ILS) (Lourenco et al., 2002; Stützle, 1999a, p. 25ff), a recent easy to implement but powerful algorithm with results comparable or superior to other state-of-the-art methods for many combinatorial optimisation problems, among them the Traveling Salesman (TSP) and Quadratic Assignment Problem (QAP). ILS iteratively samples local minima by modifying the current local minimum and restartinga local search porcedure on this modified solution. This thesis will show how ILS can be implemented for MSA.

The ability to tackle NP-hard problems has been greatly extended by the introduction of Metaheuristics (see Blum & Roli (2003)) for a summary of most Metaheuristics, general problem-independent optimisation algorithms extending the hill-climbing local search approach to escape local minima. One of these algorithms is Iterated Local Search (ILS) (Lourenco et al., 2002; Stützle, 1999a, p. 25ff), a recent easy to implement but powerful algorithm with results comparable or superior to other state-of-the-art methods for many combinatorial optimisation problems, among them the Traveling Salesman (TSP) and Quadratic Assignment Problem (QAP). ILS iteratively samples local minima by modifying the current local minimum and restartinga local search porcedure on this modified solution. This thesis will show how ILS can be implemented for MSA.

The ability to tackle NP-hard problems has been greatly extended by the introduction of Metaheuristics (see Blum & Roli (2003)) for a summary of most Metaheuristics, general problem-independent optimisation algorithms extending the hill-climbing local search approach to escape local minima. One of these algorithms is Iterated Local Search (ILS) (Lourenco et al., 2002; Stützle, 1999a, p. 25ff), a recent easy to implement but powerful algorithm with results comparable or superior to other state-of-the-art methods for many combinatorial optimisation problems, among them the Traveling Salesman (TSP) and Quadratic Assignment Problem (QAP). ILS iteratively samples local minima by modifying the current local minimum and restartinga local search porcedure on this modified solution. This thesis will show how ILS can be implemented for MSA.

Depression och psykisk ohälsa är idag ett stort hälsoproblem. Trots att motionens positiva hälsoeffekter är välkända är det få inom sjukvården som använder fysisk aktivitet som  kompletterande behandling vid depressionstillstånd. Syftet med denna kvalitativa studie var att identifiera och beskriva personalens erfarenhet och syn på fysisk aktivitet som en del av den psykiatriska omvårdnaden vid depressionstillstånd. Studien var en kvalitativ studie med strukturerande fokusgrupp intervjuer som analyserades med hjälp av innehållsanalys där ett huvudtema; Att ha kunskap och idéer men att inte få till det, två teman och sju subteman utgjorde resultatet. Resultatet från studien visade att vårdpersonalen upplevde att det var bättre förr då det var en mer strukturerad tillvaro med motion och planerade aktiviteter på varje avdelning som patienterna skulle delta i.

The purpose of this essay is to examine how health care staff, in dementia care, feel that their work situation is affected by using two methods which are specifically designed for use in work with elderly persons suffering from dementia: validation and reminiscense.To examine this, we used a qualitative research method in the form of semistructured interviews with 6 assistant nurses/nurses. These nurses work in a living with dementia targeting which have recently applied the above two methods. Of the results reveals that nursing staff feel positive effects in their work through the use of validation and reminiscense. Examples of these positive effects are greater inclusiveness and strengthen relations in the staff group, strengthen relations between staff and residents, reduced medication of soothing medicine and improved communication with the persons suffering from dementia. The results show that nursing staff feel that it can be difficult to absorb the working methods, the importance of sufficient time and continuous guidance in the exercise of the methods and the need for a genuine interest for them to generate positive effects.

This thesis describes the redesign ofequipment designed for drying bags thatis used in Fresenius Kabis´manufacturing of their nutritionmedicine in Uppsala. The need of thistask arise during the start of thedevelopment of a new packaging line werethis equipment were meant to be used. Anevaluation of the bagdryers capacity andcapability was necessary.The work started with gathering ofinformation from suppliers of the usedcomponents and from the responsibleengineers for this equipment. Aneducation to learn how the equipmentworked and how to operate it were taken.That was followed by the creation of astudy plan were the tests were plannedto test different parameters effect onthe drying result and to see if thebagdryer managed to handle the bags ofthe correct format in the pace that theequipment should be designed for.The test results detected a need ofdesigning a unit with a function thatholds the bags in place while passingthrough the dryer in order to attainhigh quality results. The results werelater used for optimization of thedesign.

Många studier har påvisat en skillnad mellan förmågan att benämna verb respektive substantiv hos patienter med hjärnskada samt hos kontrollgrupper (Caramazza & Hills, 1991; Mätzig, Druks, Masterson &Vigliocco, 2009; Szekely et al., 2005). Samtidigt bedöms aktivitetsord utifrån vissa studier vara mer krävande att tolka, vilket kan vara en bidragande orsak till skillnader i benämningsförmåga (Liljeström et al., 2008; Mätzig et al., 2009).Action Naming Test (ANT) är ett verbbenämningstest utformat av Obler och Albert 1979 (Barth Ramsay, Nicholas, Au, Obler & Albert, 1999), vilket översattes till svenska och normerades av Lindahl och Oskarsson inom ramen för ett magisterarbete i logopedi (2011). I normeringen genererade vissa ord många felsvar och sågs som problematiska, och en reanalys av det insamlade materialet efterfrågades. Syftet med föreliggande studie är att genomföra en förnyad analys av insamlade data och ta fram en ny normering för ANT i en population svenska vuxna, efter exkludering av problematiska ord.I syfte att undersöka vilka ord som gav upphov till många felsvar och orsaker till detta, gjordes en ny genomgång av 120 tidigare insamlade testprotokoll, samt en felsvarsanalys baserad på Barth Ramsays och medarbetares utvecklade modell (1999). Efter genomgång av angivna svar, analys av felsvar och ordens användningsfrekvenser i svenska språket, exkluderades tolv ord.  Jämförelse av resultat mellan tre åldersgrupper (20-30år, 31-65år, 66-83år), två utbildningsnivåer (?12 år, ?13 år) och kön gjordes både före och efter borttagning av de tolvorden.