It generally takes 10 to 12 years for a new drug to hit the market. The pharmaceutical industry invests huge sums in these early stages of research and development. In spite of the rapidly rising research and development expenditures fewer and fewer blockbuster drugs are being developed. Longer lead times and aggressive generic post-patent competition have narrowed the timeframe for the pharmaceutical companies to profit on their investments.In the face of these threats the pharmaceutical industry has developed a battery of strategies to prolong market exclusivity and to maximize return on investment. These emerging strategies are commonly known as Life cycle management (LCM), which actually is more of a concept than a method.

This project aims at investigating if the use of UML as a support to small-scale development ofan embedded system is relevant. The investigation is conducted by using UML during the initialphase of the development ofTelfafill, a filling machine by the company ?Telfafill AB?. The aimof the development of Telfafill is to separate the user interface from the control unit. In additionto this main objective, Telfafill AB would like possible changes to, and additions of,functionality of the filling machine to be investigated.Within the boundaries of this project, the development of Telfafill reached a full requirementspecification of the proposed system, and contact was made with potential external developers.No prototype construction had been started when the project ended.

Rising complexity in the development of real-time systems has made it crucial to have reusable components and a more flexible way of configuring these components into a coherent system. Aspect-oriented system development (AOSD) is a technique that allows one to put a system?s crosscutting concerns into"modules"that are called aspects. Applying AOSD in real-time and embedded system development one can expect reductions in the complexity of the system design and development. A problem with AOSD in its current form is that it does not support predictability in the time domain.

At the Department of Technology and Built environment at the University of Gävle there was an interest to study GNU Radio, which is an "open source radio project. The project is based on that most of the radio signal processing is made in an ordinary PC. The idea behind this degree project was that in a laptop there are several radio transmitters/receivers that takes space, generates heat and transmit in varied frequency band etcetera. All these radio transmitters/receivers could be replaced with a Software Defined Radio system. It means that one common, general radio hardware is used to different communications such as: WLAN, Bluetooth, GPRS, 3G etcetera. The waveform is generated in the software, which makes the system very flexible.

Purpose: The objective of this study is to illustrate how participants in leaderless based projects communicate with each other. Several studies have focused on technology-supported projects, such as open source projects, with an established project manager and goal. There is a lack, to the best of our knowledge, in studies that deal with the communication pattern in a leaderless computer supported collaborative project.Method: We have chosen to use a quantitative method where we systematically group several messages according to their content. This method was used in a similar study to illustrate the communication between participants involved in an open source project. We have taken the same Kripendorff based method and adapted it to our study by adding more descriptive variables.Theoretical perspectives: Manuel Castell discusses the aspects of a new communication power that is rooted in the individual as part of a larger creative audience.

This bachelor thesis aims to explore the public?s personal connection and attachment to place, as well as their perception of changes in the built environment that has occurred in close proximity to the area. Based upon a questionnaire carried out in a public square in Gothenburg, namely J?rntorget, the study examines the impact of the construction of two high-rise buildings that was initiated roughly five years ago adjacent to the square. The essays theoretical framework is based on the concept sense of place, a concept which derives from the discipline of Geography. Sense of place encompasses the relationship between people and spatial settings, which includes e.g.

This study deals with the distinct difference in media attention the earthquake-disaster in Haiti and the flood-disaster in Pakistan got in 2010. There may be many reasons to this divergence, but this study focuses on how news articles can create compassion.   This study, with its critical perspective, examines how two daily papers in Sweden portray the suffering of the victims of the catastrophes in Haiti and Pakistan, and create compassion for them. Furthermore it asks the question who benefits from the newspaper?s description of human suffering in the third world.   The result shows that the manner of which Swedish daily newspapers report from the catastrophe in Haiti creates an emotional involvement, which most likely leads to compassion. Furthermore it shows potential to lead the readers to identify with the suffering people in Haiti.   The Swedish daily newspapers report of the catastrophe in Pakistan on the other hand, does not involve the reader on an emotional level, but gives them the role of a spectator.

In the current situation in the housing market and in particular the inner city much attention is directed towards achieved prices per square meter in sales. The indicator is as a principle an appropriate measure of the housing market?s health and development, and can to some extent be used to make approximations of the general economic health status of municipalities and counties. It occurs occasionally that questions about whether prices are based on fundamentals at all times.The thesis questions that very issue, not from a macro accompanying financial perspective but rather from a microeconomic perspective, where each tenant ownership in the study is a micro-object. Are the observed prices per square meter rational relative to housing cooperative?s assets or is there a lack in the observed prices anchoring the respective association's finances.

I dagens samhälle finns inbyggda system i allt från vattenkokare till rymdraketer. För att möta användarnas ständigt ökande krav på prestanda och funktionalitet måste hårdvaran i dessa system utnyttjas optimalt. Detta kan göras genom att konstruera hårdvara specifikt för den aktuella uppgiften eller att använda en mer generell hårdvara, där istället mjukvaran är anpassningsbar. I många fall kan det vara lämpligt, och i vissa fall även nödvändigt, att blanda dessa metoder för att lösa en given uppgift. En kraftfull processor kan exempelvis kompletteras med en accelerator uppbyggd av specifik hårdvara.

The main purpose of this essay is to study how classroom interaction can take place in a class for Second Language Learners (SLL).1 I have applied a case study methodology on a linguistic method used by a Teacher in Swedish as Second Language working on a primary school situated in the Southern suburbs of Stockholm. The learning method is based on extensive reading of books which comprehend several learning techniques organized into a process that support the development of linguistic skills such as discussing in a group, writing, reading and thinking in a second language. The methodology applied is based on observations, on an interview with a Teacher in Swedish as Second Language and on a questionnaire answered by 11 students that participated on ?Boksamtal?.Based on a theoretical framework about socio cultural theories on learning and scaffolding,2 I attempt to integrate theory and practice to investigate how the Teacher succeed on applying effective methods for second language learning. Through the analyses of the data is also my intention to emphasize the advantages and disadvantages of such a method.

En aktiv databas reagerar automatiskt på händelser som genereras internt eller externt i databasen. Det aktiva beteendet i ett databassystem kan ses som övervaknings-funktioner för databasen. Det innebär att kritiska system som stridsledning, sjukvård och kärnkraftverk har stor förtjänst i att använda aktiva databaser. En passiv databas, vilket är det vanligaste idag använder sig av polling och embedded code för att åstadkomma aktiviteter som finns i den aktiva databasen. Dessa lösningar genererar dock redundans, överbelastning av systemet och tidvis inkorrekt information.Vid ett systemutvecklingsarbete används oftast en eller ett antal bestämda metoder som tillför riktlinjer och tekniker till utförandet av arbetet.

This essay aims to explore the philosophical meaning of the expression ?present and real? in Clara ? or, On Nature?s Connection to the Spirit World by F. W. J. Schelling.

Beräkningskluster används exempelvis till vädersimuleringar eller produktsimulering. Microsoft HPC-kluster tillhandahåller två olika typer av beräkningsnoder var av den ena är Computenod, som körs med operativsystemet Windows Server 2008 R2, och den andra är Workstationnod, som körs med operativsystemet Windows 7.Arbetets syfte är att jämföra operativsystemen Windows 7 och Windows Server 2008 R2 för att se om de presterar likartat som en beräkningsnod. Detta avgörs med avseende på energieffektivitet samt hur de presterar i Linpack. Linpack är ett prestandaverktyg som mäter ett beräkningsklusters beräkningsförmåga i flyttalsoperationer per sekund. Studien utförs genom en experimentell metod.

The main purpose of this essay is to study how classroom interaction can take place in a class for Second Language Learners (SLL).1 I have applied a case study methodology on a linguistic method used by a Teacher in Swedish as Second Language working on a primary school situated in the Southern suburbs of Stockholm. The learning method is based on extensive reading of books which comprehend several learning techniques organized into a process that support the development of linguistic skills such as discussing in a group, writing, reading and thinking in a second language. The methodology applied is based on observations, on an interview with a Teacher in Swedish as Second Language and on a questionnaire answered by 11 students that participated on ?Boksamtal?.Based on a theoretical framework about socio cultural theories on learning and scaffolding,2 I attempt to integrate theory and practice to investigate how the Teacher succeed on applying effective methods for second language learning. Through the analyses of the data is also my intention to emphasize the advantages and disadvantages of such a method.

Abstract D Level Essay in Political Science, Spring Semester 2010 by Sangrid von Zedtwitz-Liebenstein. Tutor: Malin Stegmann McCallion. ?Democratic Accountability in Networks? The aim of this study is to highlight the problem of the democratic deficit in the private-public partnerships in Sweden. This is a comparative case study with four ideal types.