The RECK gene is a relatively new discovered gene with important implications for cancer research. The research has been primarily concentrated on the human gene with the ultimate aim to identify the invasive characteristics. Up regulated RECK is linked to significantly prolonged survival rates in patients with severe forms of malignancies. RECK is normally expressed in all cells of the body and has an important role in the balance between destructive and constructive features of the extracellular matrix. The RECK protein is a membrane-bound glycoprotein that inhibit matrix metalloproteinases which has the function of breaking down the ECM. There is a significant correlation between RECK gene expression and the formation of new vessels, presumably via the mediation of VEGF which is an important and powerful inducer of angiogenesis.

My essay begins with a story in which I portray different communicative situations at the preschool unit Myran. The children in my story are at an Early stage of development and they all suffer from multiple disabilities which inhibit their ways of communicating. Through my story, I describe how I perceive different communication dilemmas in my work place. A difficulty I cover in my essay is how the educator knows if he or she has interpreted a child correctly when it does not have a verbal communication and therefore is completely dependent on the educators? interpretations of its communication efforts.

The aim with this study was to investigate mortality in older respectively younger beech stands (Fagus sylvatica), the different types of dead wood in the forest and the availability of coarse woody debris (CWD). The research was carried out in previously managed and seminatural stands in Biskopstorp and Frodeparken, located north of Halinstad in Halland,Sweden. Data were collected from 22 stands with at least 50 % beech and with a minimum age of 5 1 years, ranging in size from 0,67 to 19,9 ha. A transect was placed in each stand, in which the diaineter on both dead and living trees with a minimum diameter of 50 mm was recorded. On seven to 13 dead trees, depending on the size of each stand, decomposition stage, primary and secondary cause of death, amount of fungi and the type of the dead wood was noted.

Introduction: The work process of a consultant can be divided into five different stages, where the entry stage is the most important when linking the subject to legitimacy. A great deal of research regarding legitimacy exists, although within areas outside of consulting. Through examining consultant's and potential client's perception of what legitimacy is and how it is created we can determine the importance of the phenomena in building a business relationship between these parties. Research question: How does legitimacy arise between a consultant and a client in the entry stage of a work relationship? Purpose: The purpose of this study is to develop a deeper understanding of how legitimacy is created in the initial stage of a new consultant/client relationship. We also intend to examine the qualities and circumstances which lead to a consultant to acquire an assignment. Method: We have, from an inductive approach of research, collected empirical data in order to gain a deeper understanding of legitimacy in the initial stage of a consultant/client relationship.

This thesis intends to examine the role of the city, Dublin, in the Irish economic growth during the 1990s. It is a case study where Dublin is compared with current theories on post modern cities as growth machines and increasingly prominent actors in the global context. The study has an interdisciplinary approach but focuses on political science issues such as power distribution, global-local governance and local political organisation. It is a theory driven study that also intends to add aspects to the understanding of the cities of our time. I argue that Dublin has faced a lot of changes during the last decades in accordance with the post modern city.

Typically, when Faurecia in Torsås are planning a new assembly line, one of the steps is to build a full-scale model of the line in card board, a form of mock-up planning. Faurecia has shown interest in finding an alternative methodology. The purpose was to explore the possibility of replacing today's cardboard based mock-up planning with models in a digital simulation environment.The purpose of the thesis has been to answer some of these complex questions; What are the benefits of using a simulation tool? In what way can we use it? If we choose to use a simulation tool, in what way does it affect our way of planning an assembly line? What are the advantages and disadvantages? Are there any economical and social aspects?Our results made us realize that a digital simulation tool does not replace the card board. On the other hand simulation could be used as a complement.

Stage Design is design for action and contains décor, side-scenes and properties, as well as costume and grease-paint. The one responsible for this is the Stage Designer, who together with the Director, creates the best conditions for the actors to perform in. The stage, where the play takes place, could be either in a theater, an auditorium, or in another sort of room, at another place, inside or outside, and where the place itself inspires to theatrical performance and expressions. This type of theater is called Site-specific theatre. Two examples of this is the workshop ?Skogen sjunger? (eng.

The purpose of this thesis was to investigate how an industrial company can increase customer value by offering added services to their core products. Theses added services can be categorized into the three different parts of the buying process. The company that was investigated is Smurfit Kappa Kraftliner in Piteå, a large international industrial company active on a business to business market. We have conducted a case study and made interviews with three respondents within the company. The result of the study show that the company offers value added services in each stage of the buying process.

Ovarian stimulation in assisted reproduction often leads to the production of a high number of oocytes. After fertilization of these oocytes, the resulting embryos can be cryopreserved for later use. Vitrification is a recently introduced method for cryostoring embryos, showing high survival rates for both cleavage stage embryos and blastocysts. Characteristic of vitrification are high concentrations of cryoprotectants and ultra fast freezing which makes the material glassily. A major concern with vitrification has been the direct contact of the cryo-solutions with liquid nitrogen.

Purpose and aimThe purpose of this thesis has been to create a deeper understanding about the impact that the digitalization of the music business in the early 2000s and also the latter change, that in this paper is referred to as the sociodigital change, has had on artist brands. We will also analyze the positive and negative effects that this development may have had on the already existing brand environment and lastly also review the true importance of the professional industry?s competence. We have chosen the following research question in relation to the purpose; In what way has the basic conditions for artist brands within the music industry changed since the digitalization of the music industry in the early 2000s? MethodFor this study we initially took an inductive approach as we formed hypotheses based on experiences and previous knowledge which we then corroborated with theories.

Early intervention is important on different levels and must be justified as a social and economic long-term investment. There is no doubt about the importance of early detection when helping children/students in need of support. What kind of support that is deemed suitable and who provides the support can be viewed from different perspectives and with different approaches. Seen from a relational perspective the special education process is a long-term process and affects not only the individual but the whole school culture and systems may need changing. This study intends to describe the importance of the learning environment and what efforts are initiated early for students in need of support from the special education point of view.

There are about 3 500 churches protected under the Heritage Conservation Act in Sweden today. These churches still belong to living congregations that want to be able to adapt them to the needs of today, just like people have done throughout history. But since the churches are protected, the congregations have to apply for a permit and that is not always given. This can lead to frustration, and you can sometimes hear representatives of the church express the view that antiquarian authorities are enemies that oppose the church. On the other hand we have the antiquarian authorities that, in a way, have to act as advocates for generations to come and make sure that there is a cultural heritage preserved for them when they grow up.

Uppsatsens titel: Ekonomistyrning av FoU-verksamhet, med fokus på styrning av utvecklingsprocessen Seminariedatum: 2007-01-18 Ämne/kurs: FEK 582 Kandidatuppsats, 10 poäng Författare: Oscar Danefors, Frank Fagerlund, Joakim Puusaari, Fredrik Rubin Handledare: Per-Magnus Andersson, Peter Jönsson Fem nyckelord: Produktutveckling, FoU, stage-gate-system, styrning, management style Syfte: Syftet med uppsatsen är att gå djupare i utvecklingsdelen av FoU-verksamheten genom att beskriva samt analysera styrningen av utvecklingsprocessen. Metod: I uppsatsen används ett hermeneutiskt perspektiv och en kvalitativ forskningsstrategi som med en jämförande design leder till att en multipel fallstudie används för att uppnå syftet. Teoretiska perspektiv: Management style, projekt styrning, stage-gate-system, resultat styrning Empiri: Studien baseras på intervjuer med ansvariga inom FoU på följande fem företag: Akzo Nobel Decorative Coatings Europe, Alfa Laval, Ericsson Mobile Platforms, Procordia Food och Tetra Pak. Resultat: Följande har funnits i uppsatsen: ? Funnit att stage-gate-system är har en stark koppling till centraliserade organisationer.? Att det finns andra system än stage-gate-system som fungerar i en decentraliserad organisation? Att risken i våra fallföretags utvecklingsprocess inte skiljer sig åt mellan olika branscher.? Att det finns ett generellt mönster i våra fallföretags stage-gate-systems produktutvecklingsprocess.? Att det kan finnas ett samband mellan bransch, utvärderingsenhet och utvecklingsprocess..

My thesis is a combination of theory and practice, where theory is meant to create a context and a background for my interpretation proposal. I wanted to ?access? the ideas that are always in the background of the reasoning which underlies both planning in a larger scale, and the design of a place. I wanted to make a ?work of ideas.? In the process of shaping the proposal, I wanted to be deleted from the site itself.

When planning new wind farms, the cost for the internal electrical grid is estimated to account for 8-9 % of the total investment cost. On top of that, the cost for accumulated reduced income over several years (due to electrical losses), has to be added. The economic lifespan is relatively long (about 20 years) which means that an error in the loss calculation could lead to a bad decision basis. The accumulated reduced incomes due to electrical losses can be higher than the initial investment cost for the internal electrical grid.Today, Statkraft Sweden is using a template number when estimating the electrical losses in a wind farm. The actual losses are probably lower than the template number which could lead to an unnecessary high loss cost when planning a new wind farm.The aim of this M.Sc.