Breast cancer is the most common tumor disease among women in Sweden. About 7000persons, having a median age of 65, are diagnosed each year with this disease. Withmammography screening, breast cancer can be detected in an early stage which improves theoverall survival (OS). 20-30 % of the breast cancer tumors are overexpressing humanepidermal growth factor receptor 2 (HER2), which is a protein that stimulates cell proliferation.Trastuzumab (Herceptin®) is a humanised monoclonal antibody that targets the HER2-proteinand prevent the signals for cell proliferation.Trastuzumab has earlier been used for treatment of metastatic breast cancer. In the year of 2007trastuzumab was approved for adjuvant treatment of patients who has been medicated withsurgery and/or radiation.The aim of this study was to investigate the effects of adjuvant treatment with trastuzumab inHER2-positive breast cancer patients.

Background: A Balanced Scorecard can be used as a tool for communicating and presenting the vision and strategic goals of an organisation in a way that is easy to understand. Implementing a scorecard will support the learning process and dialog concerning the strategy of the organisation. It will also increase the employees understanding of the organisation and motivate them to reach the strategic targets.Purpose: To evaluate and describe employees opinions of a Balanced Scorecard that has been created by the management group from a management point of view. From that, our aim is to recommend our case company, Swedish Tissue, how to implement their Balanced Scorecard. We will also give more general recommendations on how to implement a scorecard.Method: The conclusions in this thesis are the result of a case study.

Benthic invertebrates play important roles as feeding resources for many organisms in different food webs. Shifts in predation of these organisms can generate cascading effects and potentially lead to the disappearance of one or more species from a site. Cascading effects can bring impacts to organisms who aren?t even directly involved, why studies in this field are important for understanding sudden changes in ecosystems. I examined the predation from fish and waterfowl on benthic invertebrates in the shallow and eutrophic Lake Tåkern in the plains of Östergötland County, southern Sweden.

Ill health takes different expressions during different periods in life and habits during the early years affect the health during the rest of the lifetime. Bronfenbrenners ecological systems theory has been used as a theoretical starting point in this cross-sectional study. The aim of this study was to identify differences in self-rated health and health-related factors between boys and girls and between the compulsory school and the upper secondary school in Sundbyberg municipality as a basis for the planned activity in the Young Women?s shelter in Sundbyberg, as well as in other municipalities A questionnaire consisting of 24 questions based on different variables has identified disparities in health and health-related factors between boys and girls in Sundbyberg municipality (n=323). This paper found pronounced differences between the sexes in terms of sex and relationships, security, emotional support and psychosomatic complaints.

In Sweden it is of major concern to the society that every individual get the same possibilities to be able to complete and affect their education. Despite this some students with a foreign background have difficulties when it comes to homework?s. This is contrary to the goals that the government strives for, which is a more just society. The aim of this study is to analyze five elementary schoolteacher?s experiences and attitudes against the homework for students with two languages.

Dagens företag och organisationer måste ständigt förändra och förnya sig för att kunna överleva. Många av de studier som genomförts, visar att implementeringar av strategiska beslut i företag och organisationer ofta misslyckas och implementerings-arbetet beskrivs av många forskare som en konst snarare än en vetenskap. Förändringsarbetet och i synnerhet implementeringsfasen är det som fokuseras i detta arbete. Det finns många olika orsaker till varför implementeringsarbeten misslyckas, men genomgående så lyfts den interna kommunikationen fram som en ytterst kritisk faktor. Detta är orsaken till att vi på djupet studerat detta ämnesområde.

Background: Prediabetes is caused by relative insulin deficiency and insulin resistance in the body tissue which leads to abnormal blood glucose levels. Prediabetes can over time lead to type 2 diabetes mellitus. To prevent the onset of type 2 diabetes and its complications, it is important to identify early elevated blood glucose levels and thereby prediabetes.Objective: To describe nurses' knowledge and experience regarding the management of patients with prediabetes.Methods: Qualitative descriptive design with individual interviews. Three nurses, three community health nurses and three diabetes nurses were interviewed.Results: The result can be understood from the nurses' experiences of encountering patients with prediabetes. An overarching theme in the analysis was that the nurses are working or aspiring to work preventively.

A reforming trend is captured showing that countries are shifting from defined benefit pension systems towards defined contribution systems. The reforms have been justified through predictions that the defined benefit systems will not manage to provide good enough pensions to members in the future. The newer defined contribution pension plans often include individual financial accounts where individuals have the possibility to choose how a part of their pension savings should be invested. Sweden was early to introduce such a system, which at the moment provides more than 800 funds to choose from. The aim of this thesis is to capture the market risk associated with these individual investments and does so by using Monte Carlo simulations for six selected pension funds.

I SLUTET AV 1980-talet och början av 90-talet skedde stora omvälvningar i svensk skolpolitik som fick följder för den lokala skolan. Detta kom att bli införandet av fristående skolor. En nya era i svensk skolpolitik hade börjat. En era där konkurrens mellan skolor skulle bli vardag. I Sverige har det gjort väldigt lite forskning om konkurrens mellan skolor och den forskning som gjorts har uteslutande handlat om huruvida konkurrens är något positivt eller negativt för skolor.

This study examines the cultural factors which necessitated the establishment of The Music Archives of Småland in 1991 in the city of Växjö. I wanted to know the importance of the local music tradition and the role of those people who worked to create an institution such as this. In order to do this I interviewed the chief collector of early folk music, Magnus Gustafsson, and made use of literary sources to devise questions and evaluate the results of the exercise. In this study I have made use of a model of a musical culture in a society, created by Lundberg and Ternhag, based on the theory of cultural fields by Pierre Bourdieu. According to this model, the stature of a musical culture gives different forms of musical expression certain roles, but these roles can be remodelled, reflecting perhaps political or ideological influence.

Moisture damage in kitchens is an area that many people believe to be irrelevant andnot a subject to concern, however the problems encountered might be larger thananticipated.The purpose of this essay is to get a view of how problematic moisture damagecurrently is as well as what can be done to prevent damage during the constructionand building of new housing.Statistics regarding moisture damage as well as several tools for damage preventionhave been studied and investigated. Industrial regulations have been reviewed tounderstand the requirements construction companies must legally follow during theconstruction and building of new kitchens. Home manufacturers and largerentrepreneurs have been contacted in order to get their point of view regarding theproblems with moisture damages in kitchens.The knowledge of moisture safe constructions is prevalent by home manufacturers,insurance companies and entrepreneurs. Despite this knowledge, the constructioncompanies predominately follow the industries regulations, which normally onlyimplement the minimum requirements.In order to get construction companies to design and build kitchens with increasedmoisture security, stricter industrial regulations might be needed to be implemented.Unlike bathrooms and laundry rooms, kitchens are not defined as a ?wet room? andthe regulations for the construction of kitchens are more lenient.It is difficult to detect water leaks in an early state and the moisture damage is usuallyextensive before it is discovered and repaired if the kitchen lacks moisture securedconstruction and water security.

I am in this essay to find out how to successfully combine new development with preservation of natural values, mainly large scale vegetation and ground formations.This is done by studies of three developments. The first development, Engeltofta backe, lies 7 km northeast of Gävle. The expectations of natural preservation were not fullfilled when this area, after the explotation, did not have any vegetation of value left. The second example, Östra Kvarnskogen in the community of Sollentuna, shows, as far as one can tell at the moment, a sucsessful combination of new development and preserved nature. The third example is a development in the community of Kullön. In this area the ambition of combining preservation and development was fullfilled. After studying vital documentation in each planning process, I made interviews with different actors in each of the three processes. I thereafter compared the different documents and answers from the interviewed persons to find out if there were any significant similarities or differences which could be of importence when natural values is to be preserved in new developments. My conclusion of this study is that it is of great importence to define key expressions often used in the process, such as natural values and preservation.

The purpose of this study is to examine political crimes in and women?s political activity in 18th century Sweden. The cases of political crimes which has been used range from 1700- 1789 and they form an outline of the patterns of political crime in this century. These cases contain different types of political crimes, but most common ar defamation of the royal family, defamatory writings, rumor-spreading and treason. To study women?s political activity, seven cases ranging from 1749 to 1758 have been more closely studied.

Syftet med denna studie är att bidra med en ökad förståelse för hur genus kan påverka barnets identitetsskapande. Studiens forskningsfråga är: hur kan genus påverka barnets identitetsskapande? I litteraturgenomgången belyses studiens forskningsfråga utifrån olika aspekter, såsom vilka förväntningar det finns på flickor och pojkar, språkets betydelse för barnets identitetsskapande och hur genus och identitet skapas. Studiens problemprecisering är: hur beskriver barnskötare och förskollärare verbalt att deras genusperspektiv kan påverka barnets identitetsskapande? För att besvara studiens problemprecisering har två barnskötare och fyra förskollärare intervjuats utifrån en kvalitativ intervjuform.

The aim of this study is to review the commercial quail production for eggs and meat in the world. Another aim is to review the potential for increased production. Globally the quail production is very small, except in China where it is the second largest poultry industry. The production globally is small despite the quail's rapid growth, early sexual maturity and its high feed efficiency. The quail is also used as a laboratory animal and can be reared to be released in hunting areas.