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260 Uppsatser om Dose optimization - Sida 5 av 18

Does vaccination against Feline Parvovirus protect hospitalized raccoon kits from clinical outbreaks of parvoviral disease?

The Northern Raccoon (Procyon lotor) belongs to the Carnivore-family and is a species endemic to North America. Every year hundreds of orphaned raccoon cubs are admitted into the Wildlife Rehabilitation Center of Minnesota (WRCM), a non-profit organization where all injured or orphaned wild animals are admitted and receive quality health care with the goal of being released out into the wild. The WRCM routinely vaccinate all of the admitted raccoon cubs with a killed feline panleucopenia vaccine, but despite this there are outbreaks of parvovirus infection every year where up to 50% of the admitted cubs have been euthanized or died. The objective of this study was to determine whether vaccinating the admitted raccoon kits has any significant protective effect to developing clinical parvoviral disease. A single-blinded cohort study was designed with two parallel, independent groups. One group was given a dose of killed feline parvovirus vaccine at admission, and the other group was not given any vaccination at all. Assignment to the vaccinated or unvaccinated group was on a per-litter basis and done randomly by drawing lots out of a box.

Implementation of a Simulated Annealing algorithm for Matlab

In this report we describe an adaptive simulated annealing method for sizing the devices in analog circuits. The motivation for use an adaptive simulated annealing method for analog circuit design are to increase the efficiency of the design circuit. To demonstrate the functionality and the performance of the approach, an operational transconductance amplifier is simulated. The circuit is modeled with symbolic equations that are derived automatically by a simulator..

Hur påverkasogräsuppkomsten av jordbearbetning :

Today it is common to spray against most weeds by using very expensive weed-killers. The goal for every farmer is to have as low costs as possible for their use of machines and weed-killers. Therefore it is in everyones interest to find other methods to fight the weeds. Finding a way to reduce the rise and growth of weeds already at the preparation of the soil would lower the number of laps over the field and also decrease the amount of weed-killing dose. Tests show that by harrow in the dark it is possible to reduce the population of weeds with up to 60%, but the normal reduction would be about 20-30%. To verify the results above we made tests by using two different methods of preparing the soil. We tested ploughing and harrowing in daylight and during night. Later we checked the number of different weeds in areas prepared in daylight and during night. By studying the results from the different methods used we found a considerable reduction of some kinds of weeds in areas prepared during night..

Spolmaskangrepp är ett ökande problem hos värphöns

This literature review summarizes available data on infection with the parasitic roundworm, Ascaridia galli, as a cause of disease in poultry, including the consequences of a conversion to alternative production systems. Ascaridia galli has a direct life cycle with resistant eggs that survive and are easily spread in the environment, especially in systems with bedding materials where the faecal contact is high. The infection is usually subclinical but depending on the infection dose, the symptoms range from weight loss and diarrhea to mortality. Factors such as the feed composition and genetic variation among different hybrids clearly affect the establishment rate of the infection. Ascaridia galli will probably become an increasing problem, with a shift from the traditional battery cages to alternative systems where the risk of re-infection is high.

Digital Airsoftstyrning : DAC Mark.I

The Airsoft Community always search for realism and optimal performance.When the performance and/or the realism in your AEG1 aren?t enough you turn to modifications toimprove the weapon. But to manufacture such modifications isn?t that easy, hence you turn tocompanies that are specialized in creating such devices.The goal with this project is to create a prototype of a modification called ?Programmable MOSFET?and targets optimization of the electrical components within the AEG. This means that you digitalizethe control of your AEG thus entails new functions and more stability to the system that isn?t possiblewith its mechanical predecessor.A prototype has been manufactured and programmed with functions according to requirementspecificationsthen it was tested on an airsoft-gearbox with rewarding results.

Ställtidsoptimering

Emhart Glass AB är världsledande företag inom glasflasktillverkning. Dekonstruerar automatiserade maskiner som formar glasflaskor. I Sverige finns dettvå fabriker, en i Örebro och en i Sundsvall. I Örebro tillverkar man främstreservdelar och nya delar till maskinerna medan man i Sundsvall monterar ihopmaskinerna. Det finns totalt 15 olika fabriker och kontor över världen medhuvudkontor i schweiziska Cham.Eftersom Emhart Glass Örebro har för långa ställtider på några av deras maskinerska det undersökas hur omställningsarbetet går till i dagsläget och huromställningsarbetet skiljer sig åt mellan operatörerna.

Realisering och inställning av PID-regulatorer

Denna 5 poängs rapport behandlar realisering och inställning av mjukvarubaserade PID-regulatorer. Den tänkte läsaren är en ingenjör som är intresserad av hur en PIDregulator implementeras och trimmas med AMIGO (Approximate M-constrained integral gain optimization) metoden. Alla matematiska resonemang förklaras stegvis och utförligt. Huvudsyftet med rapporten är att inhämta kunskap från referenserna, och formulera denna kunskap så att den blir lättillgänglig för ingenjörer som praktiskt arbetar med PID-regulatorer. Målet med denna rapport är att svara på frågorna: ? Hur fungerar en PID-regulator? ? Hur kan en PID-regulator implementeras? ? Hur trimmas en PID-regulator med AMIGO-metoden?.

Use of oxytocin to improve diagnosis of subclinical mastitis caused by Staphylococcus aureus

Mastitis, inflammation in the udder tissue, caused by S. aureus is a big problem in dairy cattle production. It causes suffering for the cow and curing or replacing the infected cow is costly for the farmer. It is known that beef cattle also suffer from mastitis caused by S. aureus.

Etiologi och patogenes för benign prostatahyperplasi hos hund

This literature review summarizes available data on infection with the parasitic roundworm, Ascaridia galli, as a cause of disease in poultry, including the consequences of a conversion to alternative production systems. Ascaridia galli has a direct life cycle with resistant eggs that survive and are easily spread in the environment, especially in systems with bedding materials where the faecal contact is high. The infection is usually subclinical but depending on the infection dose, the symptoms range from weight loss and diarrhea to mortality. Factors such as the feed composition and genetic variation among different hybrids clearly affect the establishment rate of the infection. Ascaridia galli will probably become an increasing problem, with a shift from the traditional battery cages to alternative systems where the risk of re-infection is high.

Vad kostar en förlorad apotekskund - en estimering av bristkostnaden för receptbelagda läkemedel på ett konkurrensutsatt apotek i Sverige

After the deregulation of the Swedish pharmacy market customers can be lost due to stock-outs. Optimization of pharmacy inventory levels has thus become increasingly important. To minimize inventory costs while considering the cost of shortages the latter must be estimated. However, the shortage cost is very difficult to compute. Thus, the aim of this paper is to estimate the pharmacy-specific shortage cost parameter and its relation to other inventory costs.

SETUP TIME OPTIMIZATION

Sammanfattning Emhart Glass AB är världsledande företag inom glasflasktillverkning. De konstruerar automatiserade maskiner som formar glasflaskor. I Sverige finns det två fabriker, en i Örebro och en i Sundsvall. I Örebro tillverkar man främst reservdelar och nya delar till maskinerna medan man i Sundsvall monterar ihop maskinerna. Det finns totalt 15 olika fabriker och kontor över världen med huvudkontor i schweiziska Cham.    Eftersom Emhart Glass Örebro har för långa ställtider på några av deras maskiner ska det undersökas hur omställningsarbetet går till i dagsläget och hur omställningsarbetet skiljer sig åt mellan operatörerna.

Inokulmmängdens betydelse för utveckling av vetets stråbasröta orsakad Fusarium graminearum : utvärdering av ett biotest

Fusarium graminearum is one of the most important pathogens on cereals and causes major crop losses around the world. The most cultivated cereal in Sweden is winter wheat. F. graminearum produces both sexual and asexual spores for dispersal. Multiple factors affect the production of these spores.

A porcine type 1 Diabetes Mellitus model, for non-invasive in vivo imaging of the glucagon-like peptide-1 receptor in the pancreas, using [68Ga]Ga-DO3A-VS-Cys40-conjugated synthetic exendin-4 in PET-CT

Diabetes mellitus is a rising epidemic throughout the world and there is currently great interest in quantifying the beta-cell mass (BCM) in vivo non-invasively. In the present experiment, the feasibility of in vivo imaging of the glucagon-like peptide-1 receptor (GLP-1R) in beta-cells was examined, using the positron emission tomography (PET) tracer [68Ga]Ga-DO3A-VS-Cys40-exendin-4 as a marker, in native pancreatic beta-cells of a porcine diabetic animal model and healthy controls. Eight Swedish high-health domestic pigs were randomly assigned to be either controls or made diabetic using streptozotocin (STZ). The experiment proceeded during eight weeks, starting with an acclimatisation period. Once the pigs had been socialised they underwent surgery for the insertion of a jugular vein catheter, allowing induction of diabetes with STZ, intravenous (i.v.) injections and stress-free blood sampling. Development of diabetes was confirmed by clinical examinations, blood glucose values and insulin-staining of pancreatic sections post mortem. The diabetic pigs were insulin treated and responded well.

Opioder som smärtlindring till häst

Opioids are considered the "golden standard" in pain management for both humans and small animals, but is used less often in equine medicine - probably for fear of side effects. Are there any studies that suggest that side effects are a major problem, or is it lack of experience which is the greatest obstacle to use? As early as 1937 it was shown that morphine and morphine derivatives provide analgesia in horses. For species other than horses used opioids often both pre-, intra-and postoperatively. They relieve pain effectively and are often included in the anesthesia protocol.

Kostnadsoptimering av singelfrekvensnät för marksänd
digital-tv med Simulated Annealing

I det här arbetet har algoritmen Simulated Annealing undersökts med avseende på dess möjlig att användas för att minimera av kostnaden för ett singelfrekvensnät för digital tv. Undersökningen är gjord genom att simulera ett antal testfall för att utreda hur olika ingående optimeringsparametrar inverkar på slutresultatet. Alla försök har genomförts i ett egenkonstruerat simuleringsverktyg, gjort i Matlab. En jämförelse av resultaten för två olika sätt att hantera täckningskraven har också gjorts, Simulated Annealing med- respektive utan straff metod. Alla genomförda försök har genererat en betydande kostnadssänkning jämfört med startkonfigurationen.

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