The WT1 gene is a complex gene originally known to suppress cancer in kidneys. Studies of WT1 knockout mice have confirmed the important role of WT1 in the pathogenesis of Wilms? tumour, a tumour which counts for 95% of all childhood renal tumours. In that case the WT1 gene acts as a tumour suppressor gene. Subsequent research has shown that the WT1 gene in many other cases acts as an oncogene, e g in leukemia or lung cancer (even though these cancer forms can emerge as a result of many other aetiological factors).

AbstractThe purpose of this thesis is to describe and analyse Europol. The research questions are:- How would increased powers for Europol impact on the cooperation between Europol and police authorities in EU-member states?- Which one of the two theories transactionalism and neofunctionalism can best create an understanding of Europol and its integration with the police of the member states?In so doing the study applies a qualitative method.Europol is the European Police Office and it was established through the Maastricht treaty in 1992 with the purpose of making the integration between police of the EU member states more efficient. In order for Europol to make integration between the police of member states more efficient it can be suggested that it needs for Europol to develop into having executive powers.One conclusion of this study is that Europol is an important tool for integration in the EU but there are at least three issues that are influencing the level of effectiveness in the integration work between the police of the member states; possible mistrust, that Europol has no executive powers and that it is voluntary for member states to participate in assisting Europol with information. Another conclusion is that Europol can be understood through an integration perspective when transactionalism and neofunctionalism are complementing each other..

Diabetes mellitus type 2 and chronic obstructive pulmonary diseases (COPD) are two of the most common diseases in the world and the amount are increasing. The treatments of these diseases are self care and a change of lifestyle. For this to be successful there is a need for the person to have knowledge about the diseases and a motivation for making changes in his or her lifestyle. Most of this information is given by the district nurse at the health centre. It is important to get a better knowledge of these persons experiences and how they used the information given to them.

The students are usually eager to develop their mathematical learning. However, the Skolverket can see that this eagerness passes in the early years of school. A study shows that a varied mathematical education creates enthusiasm to learn, which can decrease the negative view of mathematics.The purpose of this study is to see how five pedagogues use laboratory mathematics, their approaches to laboratory mathematics as well as to find out their role in the laboratory education. The result of the study is based on interviews with the pedagogues, who are all teachers for students in year F-3. All of the pedagogues work in a laboratory way, but to different extents.The study shows that the pedagogues aim to make the mathematics as concrete and everyday as possible.

CSR is a far reaching concept and practice, whose popularity and diffusion has increased rapidly in recent years. Research indicates that CSR has made an evolutionary journey from primarily being characterized by reactiveness to develop into a risk minimizing and proactive competitive advantage and should be looked upon as an answer to heightened societal pressure and awareness. Based on a review regarding different relevant theoretical perspectives, this master thesis discusses CSR as a concept and practical matter in relation to various strategically chosen representatives of a selection of professions.Moreover, the data were collected through in-depth semi structured interviews. The findings show that CSR is a contemporary and highly context dependent phenomenon whose inherent multiplicity brings a distinct aspect of uncertainty to it, in terms of both meaning and practice. And in some parts there is a reluctance to communicate CSR due to a fear of missing out of important aspects.

All companies wants? to be as profitable as possible. The company in question is one of the leaders in it´s field in Sweden. In order to increase profits as much as possible it is important to identify and eliminate eventual quality defect cost as far as possible.This study was performed in Huddig AB, and the purpose of this study is to try to develop a routine for monitoring the quality defect costs, and to improve communication and create feedback between production and aftermarket.In addition to an extensive literature review on quality defect costs most of the work have been conducted at the company. Own observations and interviews have been done with the staff to get a picture of the current situation and to try to come up with improvement proposals.During the study it was proved that much of the quality defect costs in essence, derived from the production, which is seen as positive because it is the easiest part of the company to improve.

This thesis aims to develop proposals and models for a modular electronics construction to a future D250S Dual battery charger. The aim also includes investigation of possibilities to use some of Texas Instruments C2000 microprocessors. The reason for this is that CTEK SWEDEN AB wants to renew the present D250S Dual battery charger and lower the manufacturing costs. The thesis work has involved gathering theoretical facts for the development of a design on the modular electronic construction, the choice on which microprocessor to use, the choice of electronic components and facts about peripheral equipment to the D250S Dual. With the theoretical there has been developed different solutions to the proposed hardware and software solutions with comparisons in aspects of positive and negative.

The study aims to shed light on the phenomenon of employeeship at a Swedish Staffing Agencise . This has been done on the basis of two questions. How can employeeship look like in a service? What is the role given employeeship in developing contexts? In order to answer the purpose and issues have a quantitative approach been used. Based on the theoretical frame of reference has the form of surveys created.

This has been a practical innovation graduation project withthe focus of studying the impacts of downsizing on a learningorganization. The study took place at Karlsson Spools in Sala.This has been a part of an ongoing EU project funded by theEuropean Social Fund, ESF. We have, with the help ofinterviews and surveys, gathered information on the presentsituation and with the help of theoretical studies built aframework on how a learning organization is viewed intheory.During our study we found that there are many componentsto a learning organization. The company in question hasdisplayed some qualities that characterize a learningorganization such as a plan to train and further develop theiremployees. The problem we found was lack of communicationand how this has resulted in a less successful outcome of theongoing courses.

The aim of the study is to find out what pre-school teachers perceived of the curriculum, regarding esthetic subjects. The study is built on the teachers thoughts and ideas about the esthetic work, and how it is supposed to help all children develop. How the teachers has interpreted the curriculum points on how they have chosen to work with the esthetic subjects. The study is based on interviews with six teachers, from two pre-schools. The material from the interviews has then been analyzed with theories and earlier research.The result shows that the teachers think that the esthetic expressions are a language, and that the pre-school is supposed to give the children the opportunity to experience different types, for example dance, music, drama and art.

During twelve weeks of practice experience at the company Sydved AB, I received the mission to develop a structure for the company?s internal communication. A part of this mission was to find out what the company?s employees thought of Sydveds internal communication and the most important; Sydveds intranet called ?Outlook?. Due to Sydveds plans of developing the intranet I designed and accomplished an inquiry-study to find out about the employee?s opinions on the company´s internal communication and in particular their intranet.The answers I want from this study are if I shaped the inquiry-study correctly the first time.

The aim of this bachelor?s thesis is to develop knowledge about how librarians experience their professional identity, argue for their competence and describe their profession based on their professional skills, tasks, and status. The method that is used to answer the questions of the study is semi-structured interviews with five public librarians. The theory used in this essay is Ørom?s six librarian identities plus Schreiber?s experience intermediate identity.

The youth of today grow up with all the new ways to communicate that new technology provides. A lot of young people chat on the Internet. Adults often lack experience and knowledge about this way to communicate. This is a study of teenagers and adults values and views on teenagers online chatting. It focuses on area of use, meaning and effects on young people.

During spring 2007, I Matilda Lindblom, undertook my Bachelor Degree project in Furniture Design. The supervisors were Agneta Stake at Nola in Stockholm and Leo Jóhannsson, teacher and examiner at Carl Malmsten CTD in Stockholm.The project was based on three elements:? Cooperate together with a producer for professional supervision? Learn to work from a given design brief.? To learn more about industrial production? Learn more about furniture for public areasI contacted a furniture producer called Nola AB, in Stockholm, who became my work partner during this project. The asked me to design a piece of furniture where you can sit and work with a laptop on. The target was for public areas, for example in parks, malls, or at airports.In cooperation with Nola, my ambition was to develop this piece of furniture that was the answers on their wishes and demands.

In order to understand user behaviour and navigation patterns, user logging is today widely used in analysis and development of user interfaces. These user logs tend to be quite many and can contain a lot of different data. A big issue is how to process and display this data in a perspicuous way to the stakeholder. This study is about how to develop a prototype to handle this issue. It was solved by various methods from human-computer interaction.