The following text constitutes an attempt to present the French philosopher Gilbert Simondon's genetic ontology through an account of his reconfiguration of the problem of individuation in his doctoral thesis from 1958, L'individuation à la lumière des notions de forme, information, potentiel, métastabilité. The intention is to show how Simondon through this reconfiguration of a classical philosophical problem ? in which concepts and schemas from contemporary physics and technology is utilised in a critique of the bi-polar hylomorphic schema as its traditional, substantialistic solution ? becomes able to articulate an anti-substantialistic and anti-reductionistic ontogenesis as first philosophy. A systematic philosophical conception that according to Simondon precedes every critical investigation of the subject as well as every scientific ontology ? not by establishing a pre-critical position, but by exceeding Kant's critical position: that is, through a displacement toward a conception of the transcendental conditions for the genesis of being and thought as real conditions, rather than conditions of mere possibility.

WSP building physics in Stockholm has certified the preschool Temmelburken in Bromma with the system of certification Miljöbyggnad. The rating of the building became BRONZE. In this thesis the preschool has been investigated with respect to the three areas: thermal climate, use of energy and improving of the level of certification. The thermal climate at the preschool has been investigated by a questionnaire survey and by measurements in order to do comparisons between the results from the two investigations as well as with the results of the simulations that WSP has done at the certification of the preschool. The differences between the results from the simulations and the questionnaire survey for winter as well as from the measurement performed with a comfort meter the 19th of March are concidered to be reasonably small since they give rise to the same rating according to Miljöbyggnad.   Operational data for the use of energy for the preschool have been obtained in order to do comparisons with simulations performed by WSP and Svenska Besiktningar AB. The comparison shows that the simulated values for the specific use of energy are lower than what the real specific use of energy would be for the preschool, since just the operational data for the heat energy is higher than the simulated values. At the investigation of the possibility of improving the level of certification it was found that the rating of the preschool can be raised from BRONZE to SILVER by improving the ratings of the ?thermal climate summer? and the ?daylight?.

At SLU, Divison of Reproduction, Dept of Clinical Science, there is an ongoing project on the development and evaluation of new methods for the assessment of stallion semen quality. This EEF-study, which is a part of that larger project, has focused on the effects on motility and fertility of stallion semen of two different extenders and selection. Both an objective method and a subjective method for analysis have been used and compared in the study. The increase in the use of artificial insemination with cooled semen in Swedish horse breeding over the last decade is thought to play a part in declining foaling rates (Kareskoski et al, 2006, Kuisma et al, 2006). This calls for better evaluation methods of semen quality since cooling and transportation put higher demands on semen quality in order to maintain fertility (Aurich, 2005).

This article starts with a review of the literature regarding the normal reproductive physiology of the mare, normal luteolysis, different causes of prolonged luteal phase and theories behind these. The article also presents a study where it was examined if treatment with human choriongonadotropic hormone (hCG) during the luteal phase induces prolonged luteal phase in mares, thus preventing estrus. The study consisted of two parts: one intensive study of eight mares at the former Department of Obstetrics and Gynaecology at SLU, Uppsala, Sweden and one field study of seven mares at a stud farm 70 km north of Uppsala. The mares in the intensive study were divided in two groups: one with four mares that were injected with hCG in luteal phase when they had a follicle of minimum 30 mm and a second group with four mares that were injected with sodium chloride at the same time. These mares were examined with ultrasonography and blood samples.

Penicillin G (benzylpenicillin) is the most commonly used antimicrobial substance used in equine medicine today. Two forms of penicillin G are available for equine use; one form is the poorly soluble penicillin G procaine and the other is the very soluble sodium salt. Although penicillin has a wide safety margin and is considered to possess a good tolerance, reactions due to side effects are sometimes encountered, which commonly is named ?penicillin-shock?. The etiology behind penicillin shock in horses is not completely understood, but the most common reason is believed to be procaine toxicity.

We have different kinds of signal processing everywhere around us in our everyday life, in our cellphones, when we are listening to music, watching TV etc. This makes signal processing a very interesting and important technical area, where the demand of skilled engineers sets the limit of what is possible.Working with signal processing requires in-depth knowledge in areas such as mathematics, physics, electronics, and other related areas. For this, it has traditionally been demanded by a talented developer to also master the advanced programming languages such as C / C + + and Assembler.This has begun to change; today there are several companies that offer graphical development environments for signal processing, environments where programming skills are not needed anymore, and the focus can be on signal processing instead.The goal with this project is to build a corresponding graphical development environment to reach an understanding of what is required of these systems, and also to grasp what opportunities that are available within graphic programming. Inspiration for the work has partly arise from some of the tools available on the market, and partly from previous theses that have been written about graphic programming.The challenge lies in creating a program that can execute signal diagrams in real time from given signal blocks, and be able to handle feedback loops in an efficient way and to do so at the lowest "cost" in terms of clock cycles as possible. This should also be compared against to code, compile and run a complete signal diagram directly.To increase the usability it should also be possibility to externally manage in real time the parameters of the signal diagram during execution.The interface is a separate program, which is to some extent similar to Matlab Simulink, where a signal diagram is drawn up graphically by connecting wires between different signal blocks.

Constantly growing demands from the costumers in the Automotive industry forces the subcontractors to seek alternative ways to compete. One parameter of quality is the components tolerance against NVH(Noise, Vibraion & Harshness) aspects. Kongsbergs Automotive has developed a new gear shifter platform (Shift-by-Wire) that is sold to Alfa Romeo and used in of their car models. However, the company is not pleased with the components sound quality, therefore the main purpose of this thesis is to develope a number of concepts that is supposed to enhance these NVH-aspects.To get an understanding of the problem an analysis of the causes of the emitted sound has been done parallell to a product decomposition, function decomposition and a Ishikawa-diagram. Together with these methods has a litterature study been performed to get familiar with the physics of an impact and especially the emittment of noise.

Utifrån arbetsmodellen Learning study, med variationsteorin som utgångspunkt har forskning genomförts i två klasser i Sverige med syftet att försöka identifiera kritiska aspekterna för elever i årskurs nio inom ämnesområdet det vita ljuset och dess färgspektrum. Studien är en vidareutveckling av en tidigare genomförd studie i Hong Kong och har därför även haft till syfte att undersöka om de identifierade kritiska aspekterna är generaliserbara från en skolkontext till en annan kontext.Den svenska skolan styrs nationellt utifrån styrdokument, skollag, läroplan och kursplan för skolämnet och läraren har även riktlinjer för att få en yrkesetisk förankring. Dessa delar är viktiga att läraren tar i beaktning inför planering av undervisningen. Elevernas bakgrund och förkunskaper i ämnet är av stor vikt för läraren att ta hänsyn till för att de ska kunna ta till sig undervisningen om det som läraren har tänkt att de ska lära sig.I denna studie kunde åtta kritiska aspekter identifieras i de två klasser som undersökningen genomfördes i. Fem av de kritiska aspekterna var redan identifierade i Hong Kong.

Eutrophication of the Baltic Sea is a serious problem. A major contributing factor is diffuse losses of phosphorus (P) from agricultural land in surrounding countries. In order to estimate P losses, environmental monitoring of small agriculture-dominated catchments is being carried out in most of these countries. Evaluation of the risk of P leaching to waters is usually based on chemical tests originally developed to quantify the amount of soil P available for plant production. The tests are performed in different ways in the different countries and a number of different extraction agents are in use.

This report is the result of a degree project in building engineering, at an advanced level. The project evaluated a building from a technical and historical point of view, and focused on its energy consumption, particularly the energy used for heating. The building in question was a small apartment building in Strömsholm, Sweden. It was made in 1902, from vertical logs, a not so common form of the traditional log house. The goal of the project was to evaluate if the energy consumption could be reduced in accordance with building preservation regulations, that is without damaging any of the building?s cultural or historical values.The building was surveyed with the help of archive and literature studies, interviews and inspections.

Syfte: Syftet var att granska det vetenskapliga underlaget och analysera om det fanns effekter av bl?b?rsintag p? plasmaglukos (P-glukos), systoliskt blodtryck (SBP) och diastoliskt blodtryck (DBP) hos vuxna med normala niv?er av P-glukos, SBP och DBP. Metod: En systematisk litteraturs?kning gjordes i databaserna PubMed och Scopus d?r randomiserade kontrollerade studier efters?ktes. Inkluderad population var individer med normala P-glukosniv?er och blodtrycksniv?er samt utan funktionsneds?ttning eller diagnostiserad sjukdom. Interventionen var f?rska, alternativt frysta bl?b?r eller frystorkat bl?b?rspulver.

Hjärtsvikt är en vanlig orsak till ohälsa i Europa inklusive Sverige och har en prognos som liknar andra dödliga sjukdomar. Vanliga bakomliggande orsaker är kranskärlsjukdomar, diabetes och högt blodtryck. Hjärtsvikt karaktäriseras av att hjärtat inte kan pumpa runt blod i kroppens vävnader på ett tillfredsställande sätt och detta ger upphov till att plasma läcker ut i omkringliggande vävnader. Symtomen varierar från lindriga till livshotande besvär beroende på var ödemen uppträder i kroppen. År 2007 vårdades cirka 218 000 personer för problem relaterade till hjärtsvikt i Sverige.

The development within the textile industry is always ongoing with development of new andbetter textiles, which often mean the use of non-natural materials like polyester. This doesn?t lineup with the work shared around the world against an improved environment, so the idea came touse a form of linen fibers instead of polyester as the reinforcing material together with cotton.The idea was to use flax, linen of low quality, which is seen as a waste product and garbage inthe production of high quality linen and flax seed oil. This flax of low quality needs to beseparated before it can be used in cotton spinning machines. Fireball 2 is just that, a process toseparate flax fibers through the treatment of a technique called electrohydraulic discharge.The thesis works goal is to evaluate the Fireball 2 process ability to separate flax fiber.

Tumörmarkörer är substanser som frisätts i kroppsvätskor från cancerceller. Markörerna används inom sjukvården för att upptäcka och följa upp maligna sjukdomar med analyser av markörerna i serum/plasma. Tre av dessa är cancerantigenerna CA 125, CA 15-3 och CA 19-9. Syftet med studien var att verifiera analysmetoden för tumörmarkörerna CA 125, CA 15-3 och CA 19-9 på två Roche Cobas e411 instrument (instrument 1 och 2) inför införandet av dessa vid avdelningen för klinisk kemi och transfusionsmedicin, Lnadstinget Kalmar län. De av företaget rekommenderade cut-off värdena på Roche Cobas e411 (Roche Diagnostics) är för CA 125 <35 kU/l, för CA 15-3 ?25 kU/l och för CA 19-9 <27 kU/l.

Antalet läkemedel som lanseras på marknaden har minskat under mer än ett decennium, vilket väcker frågan om huruvida det finns brister i de metoder och resonemang som används vid utvecklingen av ett nytt läkemedel. Syftet i den här litteraturstudien var att utreda delar av frågan kring eventuella brister med hjälp av följande frågeställningar: Vilka in vitro potenser kan man hitta vid en litteratursökning för några på marknaden etablerade humana och/eller veterinära läkemedelssubstanser? Hur förhåller sig in vitro potensen för dessa substanser till den terapeutiska plasmakoncentrationen/det terapeutiska intervallet som har fastställts för dem? Vad finns det i dagsläget för teorier kring eventuella brister i den rådande läkemedelsutvecklingsprocessen? In vitro potens-data för nio etablerade läkemedelssubstanser samlades in och jämfördes med respektive substans terapeutiska plasmakoncentration och en kvot erhölls som sedan relaterades till det resultat som presenterades i en mastersuppsats i farmaci av Fabian Göransson där motsvarande kvot genererades för 150 etablerade läkemedelssubstanser. Det sammanvägda resultatet, med tyngdpunkt på Fabians Göranssons resultat, visar att antagandet att den terapeutiska plasmakoncentrationen är minst tre gånger högre än in vitro potensen kan leda till främst överestimering men också underestimering av den terapeutiska plasmakoncentrationen och att substanser tenderar att vara mer potenta in vivo än in vitro. Därför behövs en högre grad av flexibilitet när ovan nämnda antagande praktiseras under läkemedelsutvecklingsprocessen. Efter en kortare utblick över några teorier kring brister i dagens läkemedelsutvecklingsprocess verkar det som att läkemedelsindustrin behöver revidera samt ifrågasätta lämpligheten hos de principer som idag praktiseras inom området. .