Introduction The genetic skin disease epidermolytic ichtyosis is caused by mutations in either keratin gene 1 or 10 and leads to blisters and hyperkeratosis of the epidermis. At cellular level the disease is seen as aggregates in the keratin filaments. Since medicines are hard to investigate and produce mainly due to lack of reproducible model systems, there is no good treatment available for this disease today. In this article we describe how an in vitro model consisting of cells from a stable cell line transfected with expression plasmids to mimic patient cells, may be a possible alternative for screening compounds for therapies. The first step was to generate an expression plasmid required to complete the in vitro model.

Molar Incisor Hypomineralization definieras som ett specifikt tillstånd orsakat av störningar i den tidiga fasen av emaljbildning av en eller flera permanenta första molarer med eller utan involvering av permanenta incisiver. Tidigare studier har visat att standardiserad intraoral fotograferingsteknik kan vara användbar för epidemiologiska studier av emaljdefekter. Denna studies syfte var att utveckla och utvärdera en fotografisk klassificering av allvarlighetsgraden av Molar Incisor Hypomineralization genom att studera metodens validitet och reliabilitet. 164, 10-12 åriga svenska barn granskades fotografiskt avseende prevalensen av Molar Incisor Hypomineralization. Först granskades endast första molarens ocklusalyta, därefter ocklusal- och buckalyta.

Abstract Essay in political science, C-level, by Patrik Larsson, autumn semester 2007.Tutor: Susan Marton The battle over the agenda-Can media be regarded as an individual political actor? The purpose of this essay is to study to what extent media can be regarded to function as an individual political actor. In other words, do the media have more power over the political agenda than the politicians and do the media influence how the politicians make their decisions. This research is a case study and to be able to complete the intention of this study I have used Maxwell McCombs and Donald Shaws theory, the agenda-setting theory. From this theory I have used four aspects to analyse my material which has consisted of editorials from a Swedish newspaper, interpellations and debates that belong to the interpellations. The aspect I have worked with are, how the problem is defined, who is responsible for the problem, what values and which solutions are expressed.  I have used a qualitative text analysis as my methodological approach which means that the results of my study are my interpretation of the material. My conclusions are that the media in this case shouldn?t be regarded as an individual political actor because there is no tendency that shows that the media has influenced the government in their decisions concerning the real-estate tax.

Hägglunds Drives in Mellansel, Sweden, manufacture radial piston hydraulic motors foremostwithin applications in the industry. These motors have several sliding contacts, one of these, isthe contact between piston ring and cylinder bore. The radial piston hydraulic motors advantageis to produce high torque in very low rotation velocity, this result in that the maximum slidingvelocity between piston ring and cylinder bore, during the whole stroke, is very low. Theconsequence of this low sliding velocity is that the contact between piston ring and cylinderbore, during the whole stroke, is bound to the boundary lubrication regime. This result in, thatthe piston ring is exposed to wear, thus affect the service life of the complete hydraulic motor.To minimize wear of piston ring, it is essential to determine the oil film thickness between thepiston ring and cylinder bore.

The thesis was performed at Forsmarks Kraftgrupp AB in the department ofmechanical engineering, FTCM. Forsmark nuclear power plant has had problems with cracks in some of the controlrods which are placed in the reactor at Forsmark 3. To investigate the cause of this,material samples were taken from five of the damaged control rods. This sampling ofthe rods resulted too short rods to be transported in the shipping container to theinterim storage facility for used nuclear fuel in Oskarshamn. Control rods are crucial components in a nuclear reactor, regulating the reactoreffect by blocking or unblocking fuel rods. Control rods which have been in thereactor are always handled under water in order to protect against the radiation theyemit. The task was to design a control rod adapter that extends the control rod sotransport can be performed from Forsmark. The goal of the work was a complete setof blueprints so the control rod adapter can be manufactured and mounted on theshort control rods and then be transported to the interim storage facility. The work began with mapping of how control rods normally being handled from thereactor to the interim storage facility.

Discharge of inadequately treated waste water containing nutrients such as phosphorus and nitrogen as well as organic matter and bacteria is associated with a risk of eutrophication and contamination. The Swedish government has decided upon several Environmental Quality Objectives aiming to reduce the emissions of nutrients to water bodies.In Sweden, there are between 675 000 to 1 000 000 on-site sewage systems. Recent studies have shown that the function of small sewage treatment plants is in many cases insufficient. To prevent this regular service and supervision by a professional is needed. The focus of this study are small sewage treatment plants which use a technique where mechanical, chemical and/or biological reduction of pollutants is being used in the same facility to reduce nutrients in household wastewater.The aim of the study is to investigate how different municipalities ensure that small sewage treatment plants fulfill the requirements and reduce pollutants as efficient as the manufacturers claim.

Until the beginning of the 1900:th century the paper making process was handicraft. The paper machines that have been developed since then are as impressing in size as fascinating when it comes to the technique. The process has always been improved to give a better paper for lower costs, with as short manufacture time as possible. Stratified forming has been a reality since 1830. From the beginning it was applied to board and paperboard.

The problem of separating a non-rectangular foreground image from a background image is a classical problem in image processing and analysis, known as matting or keying. A common example is a film frame where an actor is extracted from the background to later be placed on a different background. Compositing of these objects against a new background is one of the most common operations in the creation of visual effects. When the original background is of non-constant color the matting becomes an under determined problem, for which a unique solution cannot be found. This thesis describes a framework for computing mattes from images with backgrounds of non-constant color, using Bayesian statistics.

The primary purpose of this essay is to study and describe what single adoptive mothers believe to be significant motives when considering adoption. This essay also describes how single adoptive mothers experience parenthood in relation to their expectations. The theoretical perspectives applied to analyse the empirical data are existentialism, the identity making process, and social constructionism. The method of this study is qualitative based on seven interviews. The material has been analysed by condensed meaning units and themes with a phenomenological approach.

Syftet med studien är att undersöka om en geografiskt begränsad marknad inom byggbranschen underlättar en implementering av Lean Construction. För att undersöka detta har jag utgått från två forskningsfrågor: vilken inställning de tillfrågade byggföretagen har till Lean Construction och hur de arbetar utifrån ett Lean-perspektiv? Utifrån ett antal grundprinciper från Lean Construction formades en enkät för datainsamling. Resultaten från undersökningen visade att respondenterna som bestod av platschefer/arbetsledare och underentreprenörer överlag tyckte att de områden som tagits upp var viktiga för en lyckad byggprocess och en stor del av respondenterna även arbetade utifrån ett Lean-perspektiv. Enkätundersökningen tog upp nio områden: samarbete, Visible Planning med detaljerade veckoplaner, Just-In-Time, slöseri, standardisering, Kaizen, innovationer, Last Planner med arbetsplanering och Percent Plan Complete från Last Planner konceptet.

One of ABB Power Systems´s business areas is HVDC (High Voltage Direct Current) technology. HVDC is used for transmissions for both short and long distances. One of Power Systems?s products is called HVDC Light. HVDC Light is a relatively new technology for power transmission, but have before only been used for motor drives applications.

The aim of this Master?s thesis is to examine how the literature criticism are in the Swedish media in the reception of the novel Mosquitoes and tigers from 2007 written by the Swedish author Maja Lundgren. A second aim is to examine how master suppression techniques have been used by the literature critics in the newspaper debate. This qualitative study is based upon a total of 52 articles and reviews from five big Swedish newspapers. The theoretical approach, literature criticism, mainly originates from the Swedish professor in Literature Science Tomas Forser and the literature scholar Gunnar Hansson.

This thesis discuss the matter of non-profit-making associations as a self regulatory technique out of a theoretical concept of power. The object for the study is the non-profit-making association Ditt Nya Hageby, which work in the neigborhood of Hageby, a suburb to Norrköping. In the study the association is placed in a contemporary postmodern social context and analyzed through semi- structured qualitative interviews, accordingly to hermeneutical method, with five active members of the association as informants. The association consists of members who lives in the neighborhood. Together with a hired organizer they realizes their own ideas in to projects which unquestionably improves the social and physical enviroment in Hageby.

The Swedish government has made the decision to transform the talking book system from an analogue system to a digital system called DAISY by the end of 2004. The purpose of this Masters thesis is to examine how public libraries are affected by this system change. This is carried out by studying the current situation in public libraries concerning the transition to DAISY. This qualitative oriented study is primarily based on interviews with four librarians and three library managers at six public libraries. Management by objectives is here seen as a suitably theoretical framework since public municipal libraries are partly regulated by the governments goals and laws.

The main purpose of this Masters thesis is to examine how Braille users needs are satisfied by The Library of Talking Books and Braille TPB. The other issues are: How do some of the library workers at TPB experience that the needs of Braille users are satisfied? Is it possible to make the service better in the future for Braille users and in that case, how? The study is based upon interviews with five persons, who have defective vision and read Braille. I have also interviewed two employees at TPB who have defective vision. To build up a complete background presentation of the subject I have chosen a book about hermeneutic interpretation to understand how historic facts influence the function of the subject today and in the future.