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357 Uppsatser om Cellular responses - Sida 6 av 24
Inneklimatet på ett kontor : Undersökning av inneklimatet vån. G4 stadshuset samt kontor på Ånghammargatan
This report describes an investigation of the indoor climate in two different workspaces. Since we a big part of our lives are staying indoors in artificial environments, and more particularly in our workplaces, we think it would be interesting to do this investigation. The technical solutions for air treatment systems began with simple natural systems without fans and where the thermal rise of the air applied. In modern time is technical air treating systems used to take care of the fresh air supply. This type of units can supply filtered air with the right temperature to the building. Well-functioning ventilation is essential to bring clean fresh air to the room and effectively remove impurities without sound- or draught problems. The indoor climate is relevant for the output capacity.
Generation of mutated expression plasmid KRT1 and comparison of HaCaT cells transfected with expression plasmid KRT1 or KRT10 concerning keratin aggregates
Introduction The genetic skin disease epidermolytic ichtyosis is caused by mutations in either keratin gene 1 or 10 and leads to blisters and hyperkeratosis of the epidermis. At cellular level the disease is seen as aggregates in the keratin filaments. Since medicines are hard to investigate and produce mainly due to lack of reproducible model systems, there is no good treatment available for this disease today. In this article we describe how an in vitro model consisting of cells from a stable cell line transfected with expression plasmids to mimic patient cells, may be a possible alternative for screening compounds for therapies. The first step was to generate an expression plasmid required to complete the in vitro model.
Samtal om texter för ökad läsförståelse : Introduktion av boksamtal i en F-3 skola
This study covers reading comprehension and the introduction of the "Tell me" approach as proposed by Chambers (1993) to a group of teachers in a Swedish F-3 school. Five teachers got to use the method for three weeks and were interviewed before and after the experiment to analyze their current ways of working and reactions to using the method in everyday tutoring. The result from the first interview showed that all of the participants had been using methods to improve the children?s reading comprehension prior to the study, but no one had tried the "Tell me" approach. After trying the method throughout the test period, all of the participants were positive about the methodology and showed an interest in continuing the use of it.
Det samiska språket : i det politsiak arbetet kring smaiska frågor
The aim of this study is to investigate oral peer review on argumentative speech and to study the attitudes towards this peer review. The investigation was performed in an up-per secondary school class, and it focused on the different types of oral responses students give each other. In addition, the study investigated in what way the students experience this type of peer review. The results show that students reflect on form and performance as well as content, but they place more emphasis on form and performance than content. Students are positive about peer review and its importance for their progress.
Påverkan av ackulturation på invandrares upplevelse av arbetets mening: en fenomenologisk studie
The purpose of this phenomenological study was to facilitate increased understanding of immigrant's experience of the meaning of work with focus on how that meaning can change as a part of the acculturation process. Participants (n=13) from eight countries answered an open question. The responses were analysed using Meaning Construction Analysis (MCA)-Minerva and the individual's life-worlds were made visible and discussed. The themes meaning of work, work, unemployment, education, adjustment, immigration, Sweden/country of origin, dreams, possibilities and self appeared as jointly shared important aspects. The results indicate that work is of central importance, and although the individuals share certain experiences, the meaning associated with the themes is of a complex and individual nature..
Utvärdering av ett kortare dehydreringsprogram för stansbiopsier från human hud och portio : Har storleken betydelse?
På histopatologiska laboratoriet vid Länssjukhuset Ryhov i Jönköping är dehydreringsprocessen i dagsläget förlagd över natt. För upprätthållande av god kvalitet på diagnos med förbättrat provflöde och utnyttjande av instrumentens fulla kapacitet önskas att ett kortare dehydreringsprogram implementeras och förläggs dagtid. Syftet med denna studie var således att utvärdera ett kortare dehydreringsprogram för stansbiopsier från human hud och portio. Detta har gjorts utifrån cellmorfologiska bedömningsgrunder och bedömning av färgkvalité av rutinfärgning med Hematoxylin och Eosin samt specialfärgningarna polykrommetylenblått enligt Unna, Periodic acid-Schiff och Giemsa. Ett material om 87 biopsier från human hud samt portio dehydrerades fördelat över gällande rutinprogram samt utvärderat kortprogram.
Reklamprat: effekter på upplevt reklamvärde och köpintention
This thesis provides the first test of the effects of ?advertising talk?, i.e. comments, discussions and opinions about advertising. Despite its prevalence quantitative research on advertising talk has been scarce and this study is thus an attempt to fill in some blanks. Hypothesizing that advertising talk will enhance consumer-perceived advertising value as well as purchase intentions and that the effects are more pronounced for talk generated by consumers as compared to marketers, I use a fictional campaign to measure responses in an experimental study.
Uppdraget - en skola för alla. Omöjligt eller möjligt? : En studie av fem lärare
This study is about what teachers in primary schools say that they are doing to create a school for all.The purpose of this study is to find out what teachers in primary schools say that they do on their mission to create a school for everyone and how they organize teaching to achieve this. The study was conducted as an interview of five teachers from elementary school of different gender and with a qualitative method because it provides a great opportunity to problematize, interpret and understand the responses of the interviewees.The results show that all the teachers think that their mission is to teach so that they can give each student what they need to achieve the goals. This may not be every day but over time, they hope that all students feel that they get so much of the teacher's time that they need..
Missilstyrning med Model Predictive Control
This thesis has been conducted at Saab Bofors Dynamics AB. The purpose was to investigate if a non-linear missile model could be stabilized when the optimal control signal is computed considering constraints on the control input. This is particularly interesting because the missile is controlled with rudders that have physical bounds. This strategy is called Model Predictive Control. Simulations are conducted to compare this strategy with others; firstly simulations with step responses and secondly simulations when the missile is supposed to hit a moving target.
Klinisk termografi som diagnostiskt hjälpmedel vid rörelsestörning hos häst :
Thermography is the assesment of the surface temperature of the horses body and it falls into the categori of physiological imaging. Thermography allows us to portray inflammation and changes in sympathetic tone in a graphical manner.
The purpose of this study was to review thermography in equine medicine and to evaluate thermography as an aid in the diagnosis of lamness in horses.
Thermography has been helpful to identyfy sprains, stress fractures, shin splints and soft tissue, tendon, ligamentous and nerv injuries and to monitor healing processes during rehabilitation. Routine thermography may reveal inflammatory responses prior to clinical signs.
In present study thermograpy gave especially valuabel information in two cases. In one horse reduced blood flow in a. saphena due to a thrombosis were visualised and in the other horse bilateral thoracolumbal radiculopati was diagnosed.
Tuta i lurendrejeri
Purpose: Exploring the relatively new technology of convolution reverb, to gather knowledge on its limitations when used practically in the production of pop music, and from these findings to learn about applications in other performing arts and sound design.
Methodology: This is a case study of creating convolution reverb by doing impulse responses (IR) and then applying them to studio recorded pop music. The empirical data consists of the final song results, notes and journals from during the process and the comparisons, as well as established litterature on acoustics, psycho-acoustics and music production.
Results: Convolution reverb can widely and freely be used in the production of music and other audio-based art forms, since our study shows that the result of a well-made impulse response from a particular room is indistinguishable from music that is actually played and recorded in the same space..
Dogs' behavioural responses to repeated positive events
Assessing the emotional state in animals is important in order to establish the quality of their welfare, therefore it is important to investigate under what circumstances animals experience these emotions and to find indicators of their existence. The aim of this thesis was to detect possible behavioural indicators for positive emotions in dogs. These behavioural indicators could be helpful to increase both dogs? and humans? overall well-being in today?s society since they could help e.g. dog owners and caretakers to interpret behaviours displayed by dogs and their intentions so they can respond accordingly.The subjects used were 9 research beagles and each dog participated in three different treatments, assumed to be experienced as positive situations, where communicative interaction was initiated with the dog by engaging in 1) physical contact (P), 2) verbal contact (V) or 3) both physical and verbal contact simultaneously (PV).
The screening for novel proteasome inhibitors as a treatment of cancer using IncuCyte FLR and fluorometric microculture cytotoxicity assay.
The problem of finding targeted medicine is a central problem in chemotherapy. From this point of view the ubiquitin-proteasome system is a highly promising object in the pharmaceutical approach. Proteasome plays a critical role in cellular protein degradation, cell cycle and apoptosis regulation.Proteasome inhibitors are substances blocking the actions of proteasome. Cancer cells are more sensitive to inhibition of the ubiquitin-proteasome system than normal cells. Therefore proteasome inhibitors have the potential to be successfully used in the cancer treatment.The study aimed to test various substances to identify possible proteasome inhibitors with the IncuCyteTM FLR image system and fluorometric microculture cytotoxicity assay.
Fankultur på folkbibliotek ? ett redskap för delaktighet
The aim of this essay is to examine fan culture?s role in Swedish public libraries. I have interviewed, via email, six librarians who encounter and use fan culture in their daily work. The theoretical elements of my essay are based on a modified set of theories by Dorte Skot-Hansen that identifies six ideal types of cultural political rationalities. My study reveals that fan culture is used in Swedish libraries as a tool in increasing user participation in library activities.
Fallet Linné : Påverkan av motivation och arbetsglädje i anslutning till organisationsförändringar
This empirical study aims to determine whether Linnaeus University's formation in 2010 and subsequent reorganization has affected the employees' perceived motivation and job satisfaction.A combined approach was used in which both quantitative and qualitative questions were asked in the survey form. 101 survey responses is the basis for the analysis and these have been associated with SDT-theory in order to draw further conclusions.The study shows that among the respondents, there is a frustration that is possibly related to the two organizational changes. They feel that they have lost confidence in management as a result of not being part of decision making. The study also conveys a very fragmented picture, members of the organization perceive that they have very different possibilities to peform well, participate and have clear goals to work towards..