Porcine circovirus type 2 (PCV2) is a common virus present in most parts of the world. PCV2 has been pointed out as the major causative agent to post weaning multisystemic wasting syndrome (PMWS) that affects pigs after weaning. The clinical symptoms of PMWS are impaired growth, diarrhoea, respiratory problems and increased mortality. At autopsy enlarged lymph nodes with depletion of lymphocytes are commonly found. Since 1991 PMWS has spread all over the world and was first described among Swedish pigs in 2003. Although PCV2 is widespread, only some pigs develop PCV2-related diseases. Why this is and what other factors that are required in order for the disease to develop is yet unknown. The main theories involve other infections, for example PRRS, and management issues but also genetic differences between pigs and/or virus strains have been suggested.

I dag kan man oftast läsa om olika säkerhetshot och risker en datoranvändare måste tänka på för att inte ge någon utomstående möjlighet att komma åt känslig och/eller privat information. Här talas det om nya virus och nya typer av trojaner som sprids som epidemier över Internet, och i bland handlar det om ett spionprogram som följer med en nedladdad fil. Det är svårt att hålla reda på alla typer av skadlig kod som nämns fast med ökad förståelse ökar också chanserna för att klara sig från smitta. Det har visat sig att utvecklingen av skadlig kod är lika stark som den inom kommersiella mjukvaror. Från persondatorns uppkomst i början av 80-talet och fram till i dag, har utveckling skett i alla områden av den skadliga kod det handlar om strategi, syfte och framförallt ren kodkomplexitet.Dagens ledande leverantör av operativsystem och webbläsare, Microsoft, lovar allt mer sofistikerade säkerhetslösningar varje gång en ny version av ett program släpps.

The Bovine respiratory syncytial virus (BRSV) causes bronchiolitis and interstitial pneumonia, predominantly in calves, and is a major cause of bovine respiratory disease worldwide. In humans, BRSV is paralleled by the closely related Human respiratory syncytial virus (HRSV), an important cause of respiratory disease, most severe in infants.The clinical signs and pathology during RSV infection is caused, not only by the direct effects of viral replication, but also by the response of the host immune system. The immunopathology of RSV has long obfuscated our understanding of the disease, and development of effective treatment and vaccines will be very difficult until greater knowledge is gained.One of the components of the immune system that has come into focus in RSV research the last few years, is the Toll-like receptor 4 (TLR4). The TLR4 receptor is well known as the receptor that binds lipopolysaccaride (LPS), and initiates the host response to bacterial infection. Recently, it has been shown that the fusion protein of RSV also interacts with, and up-regulates the expression of, the TLR4 receptor.

Uganda anses vara ett högriskland för utveckling av nya plötsligt uppdykande sjukdomar (emerging infectious diseases, EID). Grisproduktionen i Uganda har ökat drastiskt de senaste åren och en stor del av Ugandas grisar är frigående. De kan därför lätt komma i kontakt med vilda djur i deras närområde. Porcint circovirus 2 (PCV2) är ett ubikvitärt virus och etiologiskt agens för bland annat porcine multisystemic wasting syndrome (PMWS). Förutom att infektera tamgrisar över hela världen så har PCV2 också visats kunna infektera vildsvin.

Flowcytometric technology has been widely used for measurement of the absolute numbers of T-lymphocytes subsets in Human Immunodeficiency virus (HIV), defining the disease state, monitoring antiviral treatment, and identifying any risk for opportunistic infections. A manual preparing of the samples is required. More recently an automated and enclosed blood cell counting, Celldyn Sapphire has been introduced. In this study the performance of the Flow cytometer EPICS XL as a reference method for analysis of CD3+, CD4+ and CD8 T-lymphocytes was evaluated with blood from 40 individual?s samples.

African swine fever, ASF, was first described 1921, in Kenya. The virus has thereafter spread through many African countries as well as in Europe, Asia, South- and Central America. The virus is spread via three different cycles, of which one is sylvatic and includes warthogs and soft ticks. The other two are between domestic pigs and the one most common one is caused by humans, who not always realize the seriousness of precautions. The infection manifests as hemorrhagic fever, but can also be more or less unnoticed. The aim of this study was to use molecular tools to detect and partly genetically characterize ASFV both in soft ticks and in serum from domestic pigs in Uganda. Comparing viruses detected in ticks with those detected in domestic pigs I also wanted to investigate possible links between the sylvatic and domestic cycle.

The reason why I choose the subject ?Warts on teats of Dairy Cows? was because the herd I work with has big problems with skin-complaint on teats and udder. So I found it interesting to try to find the reason why the cows look like they do and even to find a way to relieve the trouble. The examine work included both a literature research, an experimental test, concerning a comparison of different teat sprays and also an inquiry-research about the occurrence of warts in practical herds in order to collect as much facts as possible. Three companies, selling different types of teat disinfectants, were willing to sponsor the teat dipping experiment. The aim of the experiment was to see if any special disinfectant had more pronounced healing effects on teat warts. The date for the experiment was 18th December 2004 to 22nd January 2005, which was going to be 5 weeks.The experiment was carried out in the herd of Ola and Eskil Carlsson in Fjärlöv, Hässleholm. The three compared teat spray chemicals were; Nova Viri Sun, Nardosept, and BlockadeTM. These chemicals were compared to one control group, which teats were treated with the ordinary chemical normally used in the herd, i.e.

Rabies kills about 55 000 people every year and more than 90% of infected humans are considered getting the disease from dog-bites. To control the disease and eventually eliminate human rabies, the most efficient and economic method is to keep the dog population vaccinated. The objective of this thesis was to evaluate the situation of canine rabies in two urban areas in Lilongwe, Malawi, where canine rabies is enzootic. In each area 200 household-interviews were conducted in September and October 2013. Focal points were awareness of the disease, human incidence as well as vaccination coverage in the dog population.

Rotavirus causes diarrhea in young mammals all over the world, including infant humans. The diarrhea leads to severe dehydration that can be fatal if left untreated. The dehydration can be treated with fluid therapy and the infection heals itself. Despite the relatively easy treatment half a million children under the age of five dies every year due to diarrhea caused by rotavirus. Rotavirus sorts into the family Reoviridae and is a double-stranded RNA virus with a segmented genome.

Rotavirus causes diarrhea in young mammals all over the world, including infant humans. The diarrhea leads to severe dehydration that can be fatal if left untreated. The dehydration can be treated with fluid therapy and the infection heals itself. Despite the relatively easy treatment half a million children under the age of five dies every year due to diarrhea caused by rotavirus. Rotavirus sorts into the family Reoviridae and is a double-stranded RNA virus with a segmented genome.

Stick- och skärskador utgör den största risken för överföring av blodsmitta i sjukvården. De vanligaste smittämnena är hepatit B-virus, hepatit C-virus och HIV, som kan åstadkomma kronisk sjukdom och t o m vara letala. Därför måste förebyggande arbete för att undvika sådana skador prioriteras. Åtgärder vid tillbud eller skada finns beskrivna i arbetarskyddsstyrelsens regelverk. Riskbedömningar är gjorda för dessa virus och rutiner är utarbetade för upp-följning efter stickskada med provtagning och i vissa fall profylaktisk behandling.

The dog is unique in the way that the adult weight can vary 100 folds between the different breeds. Despite this, most of the breeds reach adult size before two years of age. For the large-breed dogs this means a very rapid growth when some of them can have a weight gain of up to 150 times their birth weight. The most rapid growth occurs when the puppies are between three to six months old and that kind of rapid growth during such a short period of time makes these large-breed puppies very sensitive to deficits and excesses of energy, nutrients and minerals. Some examples can be excess of energy, excess or deficit of minerals such as calcium and phosphorus or deficits of protein. The rapid growth can also make the large-breed puppies predisposed to some diseases affecting the skeletal and joints.

Japanese encephalitis virus (JEV) is one of the leading causes of acute encephalitis in humans. The virus is spread by mosquitoes, mainly belonging to the Culex species. The main reservoirs are considered to be birds and pigs, with pigs constituting the most important reservoir in regard to human infection. During the last few decades the production of pork has increased significantly in Vietnam. With 90% of pigs being kept in households owning 10 pigs or less, pigs are widely spread across most parts of the country.

Middle East respiratory syndrome coronavirus (MERS-CoV) är ett virus som först observerades hos en patient år 2012 på ett sjukhus i Saudiarabien. Viruset orsakar luftvägssymptom och ibland gastrointestinala symptom. Dödligheten hos människa är över 30%. Eftersom tidigare erfarenhet har visat att nya coronavirus ofta har sitt ursprung i en djurpopulation har många studier gjorts för att undersöka spridningen av MERS-CoV och förekomsten av en eller flera reservoirer. Denna litteraturstudie har som mål att undersöka vilka bevis det finns för dromedarens roll i smittspridningen av MERS-CoV. Då flera seroepidemiologiska studier gjorts som visar att MERS-CoV eller ett nära besläktat virus har cirkulerat i dromedarpopulationen i över 20 år har man gått vidare och undersökt bl.a.

This study had two different aims. The main aim was to investigate the dynamics and impact of African swine fever (ASF) on a farm in Uganda during a recent outbreak through a case study. The second aim was to estimate the presence of two important differential diagnoses of ASF: Classical swine fever (CSF) and Porcine Reproduction and Respiratory syndrome (PRRS).The field and laboratory based case study of the farm level dynamics of ASF virus during a recent outbreak (October-December 2010) on a farm in the district of Mityana, Uganda, was conducted, using interviews, ELISA and RT-PCR. The financial impact on the farm was also estimated. The impact of the outbreak was profound.