The RECK gene is a relatively new discovered gene with important implications for cancer research. The research has been primarily concentrated on the human gene with the ultimate aim to identify the invasive characteristics. Up regulated RECK is linked to significantly prolonged survival rates in patients with severe forms of malignancies. RECK is normally expressed in all cells of the body and has an important role in the balance between destructive and constructive features of the extracellular matrix. The RECK protein is a membrane-bound glycoprotein that inhibit matrix metalloproteinases which has the function of breaking down the ECM. There is a significant correlation between RECK gene expression and the formation of new vessels, presumably via the mediation of VEGF which is an important and powerful inducer of angiogenesis.

Bakgrund: Målet med den palliativa vården är att med hjälp av behandlingar och vård bibehålla eller förbättra den livskvalité som personen har. Dock upplever de flesta personer med cancer svår smärta i det palliativa skedet. Dessutom kan personer med cancer uppleva olika former av smärta samtidigt. Smärta kan uttryckas genom både verbal och icke verbal kommunikation. Genom öppen och god kommunikation minskar risken för missförstånd och detta kan leda till ökat välbefinnande för personer med cancer.

Background: Stroke is one of the leading causes for longlasting sequelae, among themloss in cognitive function, like aphasia. Aphasia effects the patients ability to understandand express themselves in speaking and writing. To be able to reach a good level of care,the careproviders and patients ought to have the same goals and values. This requires agood communication between the careproviders and patients. Which can be problematicfor the caregivers when they don't feel secure in their way of getting close to these patients.Aim: The purpose of this study was to illuminate caregivers experience of caring forpatients with the diagnosis aphasia following stroke.Method: This is a literature study where nine studies, with qualitative design, has beenanalyzed and compiled.

Background: Heart failure is a complex condition which means that the hearts capacity topump blood is reduced. The aim of this study was to investigate how patients with heartfailure considered their knowledge and the information they received about their disease andself-care.Method: Patients suffering from heart failure, hospitalized at section 30 E (n=13), andpatients visiting the nurse led heart failure clinic (n=4) at Akademiska sjukhuset in Uppsala,were requested to participate in the study. The patients answered questions about knowledgeand information concerning self-care and their disease. Data were analyzed using SPSS 15.0.Results: The patients valued their knowledge about the disease as lower than their knowledgeabout self-care. The study showed that all the patients found the information they hadreceived about their self-care better than the information they had received about theirdisease.

Talking about sexuality -Medical staffs´ experiences of conversations about sexuality with patients at a cardiology unit The background of this essay is the taboo to talk about sexuality among people who suffer from some kind of illness. When a person gets ill and need medical attention, his or her life changes dramatically. The patients get treatment for their symptoms. The illness and treatment have often an influence on the patient?s sexuality.

AbstractThe aim of the study was to examine the relation between estimated fluidintake and real fluidintake among dialysis patients. The data were collected through study specific questionnaire and data from the medical record. Patients attached to eleven Swedish dialysis units were asked to participate. The number of patients that fulfilled the inclusion criteria were 222 persons of whom145 (65%) chose to participate in the study. The dialysis patients estimated their fluid intake for a day in average 9,06 deciliter.

Patients with COPD (chronically obstuctive pulmonary disease) often experience acute episodes of the disease. On these occasions it is usual that the ambulance nurse is the patients first contact in the care. The purpose of this study is to describe patients' experiences in acute condition of the disease COPD and the Pre-hospital nursing. The method was systematic literature review with content analysis. The results show four prominent themes on the basis of patients' experiences.

Citizens? freedom of choice has been a subject of debate in Sweden for over 30 years. This study focuses on decision making processes among patients within the Swedish healthcare system. The main conclusions are that in contrast to how patients? freedom of choice is described within governmental bills and governmental inquires and reports, patients are not following the steps included in the rational model of decision making.

The aim of the study was to describe how patients experienced communication, treatment and costs at the dental hygienist program at Högskolan Kristianstad. The study was based on a questionnaire that was made at the patient clinic. The questionnaire was conducted by the treating dental hygienist student after the treatment. The questionnaire was answered in the waiting room. Collection of the material occurred during the month of March in 2009.

Sleep has a recreating, health promotive and regenerative function. Research shows that intensive care patients suffer from sleep deprivation and bad sleep quality with considerable negative consequences.The aim of the report was to examine how much nocturnal sleep patients without ventilator treatment get and to observe factors that may influence sleep.Methods: An observation chart was used to collect data. The staff?s observation of the patients? night sleep and estimated nocturnal noise- and light levels in the patients? rooms were documented. The patients? answers to questions about pain and possible causes for their awakenings were noted.

2800 kvinnor i Sverige insjuknar i gynekologisk cancer årligen. Vanliga behandlingsmetoder är kirurgi, strål- och cytostatikabehandling. Behandlingarna har visat fysisk och psykisk påverkan och att kvinnor med gynekologisk cancer oroar sig i större grad än andra patienter med andra cancerformer. Syftet var att beskriva kvinnors upplevelser efter avslutad behandling av gynekologisk cancer. Uppsatsen genomfördes som en litteraturstudie där 12 artiklar analyserades.

Bakgrund: Målet med den palliativa vården är att med hjälp av behandlingar och vård bibehålla eller förbättra den livskvalité som personen har. Dock upplever de flesta personer med cancer svår smärta i det palliativa skedet. Dessutom kan personer med cancer uppleva olika former av smärta samtidigt. Smärta kan uttryckas genom både verbal och icke verbal kommunikation. Genom öppen och god kommunikation minskar risken för missförstånd och detta kan leda till ökat välbefinnande för personer med cancer. Syfte: Syftet med studien var att belysa hur samspelet mellan personer med cancer i ett palliativt skede och sjuksköterskan påverkade personens upplevelse av smärta. Metod: En litteraturstudie har genomförts med hjälp av åtta artiklar som har analyserats med kvalitativ ansats. Resultat: Genom kommunikation och relation mellan personer med cancer och sjuksköterskan kunde smärta lindras.

Cancer is one of the most common diseases and it affects not only adults but also many adolecents and children every year. Those who are affected of disease face many challenges that will affect their lives. The aim of this literature review was to illuminate adolecents experience of cancer and how it affects them in their daily living. The result showed that the adolecents experience many physical and mental side-effects from disease and treatment. They expressed the need of information, support and understanding from their families, friends, school and care givers.

Bakgrund: Gynekologisk cancer är en särskilt intim form av cancer och drabbar ca 2900 kvinnor i Sverige varje år. Syfte: Att beskriva upplevelser och behov hos kvinnor som har gynekologisk cancer och sjuksköterskans stödjande roll. Metod: En litteraturstudie baserad på tio vetenskapliga artiklar med kvalitativ metod. Resultat: Analysen resulterade i fyra huvudteman; förändrad sexualitet, en osäker framtid, relationer samt sjuksköterskans roll. Kvinnorna upplevde en förändrad kroppsbild, ett förändrat sexliv samt en rädsla för recidiv.

ABSTRACT Background: The ward round is a collaboration between nurse, doctor and patient. A good collaboration and communication is essential to their interrelation. Aim: The aim of this study was to investigate patients' comprehension in regard to integrity, information and participation during round. We also looked at differences about comprehension between men and women.  Methods: A questionnaire was answered by 34 patients in three wards at the University hospital in Uppsala. Results: The patients believed they could talk openly ?quite well? but they experienced it ?sometimes? disturbing to talk openly if other patients were in the room.