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885 Uppsatser om Alzheimer´s disease - Sida 11 av 59

Aktivitet som sjukdomsmarkör på kalvar i gruppsystem :

Since long, Sweden has had exceptionally low calf mortality compared to most other countries. The tradition has been to keep calves in individual pens. With increasing number of cows per herd there is now a larger interest in more efficient and economical group systems for housing calves. However it has been noticed that bigger herds have more health problems and higher calf mortality than smaller herds. The early signs of disease are harder to detect when the animals are not fed manually.

Otitis externa hos hund ? förebyggande åtgärder och råd till djurägare

Otitis externa is a disease regularly encountered in veterinary practice. It is estimated to be the most common disease in the external ear canal of dogs and treatment is often delayed due to unfortunate pet owner ignorance. Owners tend to assume that scratching of the ears and head shaking are natural behaviours in their dog and may be neglecting the problem unknowing of how severe it actually is. A literature study has been carried out to examine the causes of otitis externa in order to present a collection of measures that can be used in the treatment and prevention of the disease. In turn these measures can be advised to the dog owner and used in the home environment to make the best qualifications for healthy ears in the dog. The causes of otitis externa have been divided into predisposing, primary, secondary and perperuating causes.

Vattenjärnhaltens betydelse för mjölkkors hälsa och produktion :

Drinking water from drilled wells has a high content of iron and other minerals in many places in Sweden. Questions about the association between the quality of drinking water and the health of dairy cows are regulary asked both by advisers and dairy farmers. There are so far not many studies published about the relevance for high iron content in water and dairy cow health and production. Therefore, the aim of this study was to investigate if there is a connection between the iron content in water and the health of dairy cows. Initially a literature study was made about iron and it´s function in ruminants.

Att leva med en familjemedlem med kronisk obstruktiv lungsjukdom

BACKGROUND: Chronic Obstructive Pulmonary Disease (COPD) is a slow progressive disease affecting the family caregivers by limiting their lifestyle. Subsequently the situation can be experienced as stressful for both the afflicted and the relatives. To easier understand the needs of the caregivers of family members suffering from COPD have, it is important to get an insight into their experience of every-day life, so that medical staff can help, support and promote their health according to their needs. AIM: To illustrate caregivers? experiences of living with a family member suffering from Chronic Obstructive Pulmonary Disease.

Äldre mäns erfarenheter när sexualiteten påverkas vid prostatacancer : En litteraturbaserad studie

Background: Prostate cancer is the fourth most common cancer disease in the world and affects mainly older men. While having prostate cancer the treatment can be both medical and surgical and both these treatments can give side effects like erectile dysfunction, lost libido and hot flushes. Sexuality among elderly is often associated with taboo, but sexuality exists among elderly and is important for their wellbeing and quality of life. It is common that nurses don?t address and discuss questions concerning sexuality with patients, even though they know that sexuality often is affected while having a disease or experiencing illness.

Tuberkulos : En studie av vården av patienter med tuberkulos på Lugnets sanatorium i Växjö mellan åren 1920-1926 avseende köns- och klasskillnader

The topic of this paper is tuberculosis, especially in regard to the sanitarium movement and the efforts that were made to cure, ease and stop the spreading of the disease. The sanitarium movement was established in the late 19th century before any effective cure for the disease had been found. At this time the only treatment for the patients were fresh air, rest and good food. The paper analyses the case books for some of the patients at the sanitarium Lugnet which was situated close to the Swedish town Växjö in order to see if the treatment of the patients differed depending on gender. The result of the inquiry suggests that there were no difference in the treatment of men and women..

Feta kontra magra mejeriprodukter vid primärprevention av hjärt- kärlsjukdom. En systematisk översiktsartikel

Sahlgrenska Academyat University of GothenburgDepartment of Internal Medicine and Clinical NutritionAbstractTitle: Whole fat versus low-fat dairy products for primary prevention of cardiovascular disease. A systematic review.Author: Josefine Lindqvist, Robin Järnmark, Mathilde OhlinSupervisor: Mette AxelsenExaminer: Anna WinkvistProgramme: Dietician study programme, 180/240 ECTSType of paper: Examination paper, 15 hpDate: 2014-04-09BackgroundResearch indicates that dairy products seems to have a protective impact on the incidence of cardiovascular disease regardless fat content. Paradoxically the Nordic nutrition recommendations recommend an exchange of full fat dairy product to low-fat dairy products.ObjectiveThe aim of this review is to investigate whether the variation in fat content of dairy products have any bearing on the onset of cardiovascular disease. With regard to common risk markers for cardiovascular disease the outcome measures hypertension, hyperlipidemia and weight gain is examined.Search strategyThe searches were made in the databases Medline (23/1-14) and Scopus (6/2-14).Selection criteriaRestrictions: Human Studies, Adults, Randomized Controlled Trials, English.Data collection and analysisTwo RCTs were included. Validation of the separate studies was performed with SBU's review template for individual studies and GRADE was used for summarizing the evidence of outcome measuresMain resultsThe two included studies examined the outcome measures blood pressure, weight and blood lipids.

Preoperativ SWAL-QOL och sväljningsfunktion hos Parkinson patienter selekterade till Deep Brain Stimulation

AbstractObjectivePatients with Parkinson?s disease often have symptoms of dysphagia. These swallowingproblems have consequences for quality of life as well for the physical wellbeing of thepatients. AimThe aim of this study was to describe and correlate Swallowing Quality of Life (SWAL-QOL)scores, self-assessment of swallowing function using a visual analogue scale and the resultsfrom a fiber endoscopic evaluation of swallowing function in patients who had been selectedfor Deep Brain Stimulation in caudal zona incerta. A secondary aim was to correlate diseaseduration with results from SWAL-QOL and the fiber endoscopic evaluation of swallowingfunction.MethodTen male Parkinson?s patients (age 45-69 yrs, median 61.5 yrs) who were selected for DeepBrain Stimulation completing the Swallowing Quality of life form, as well as rating theirswallowing function using a visual analogue scale and undergoing a fiber endoscopicevaluation of their swallowing function.    ResultsThe median total SWAL-QOL score was 94% while the mean was 91%.

Att genomföra livsstilsförändringar vid Diabetes mellitus typ 2 : Sjuksköterskor och patienters perspektiv

Diabetes mellitus type 2 is a rapidly increasing disease worldwide. The disease is connected to lifestyle. Making lifestyle changes is hard. When suffering from Diabetes mellitus type 2 it is necessary to live healthy to prevent secondary diseases. Lifestyle changes includes for example changing dietary habits, become psychically active or losing weight.

Validation of a tetraplex assay for detection of antibodies in poultry serum using Luminex 200 platform.

Background: As a part of a national health control program, Statens VeterinärmedicinskaAnstalt performs diagnostics to screen flocks for certain pathogens causing high mortality,morbidity and/or serious economical losses. There are several viruses in the programincluding IBDV (infectious bursal disease virus), IBV (infectious bronchitis virus) and NDV(Newcastle disease virus). Method: 96 serum samples were collected from different poultryflocks in Sweden and analyzed by ELISA, which are currently used in the health controlprogram as well as by a commercial prototype of a multiplex immunoassay manufactured byLuminex Corp., which is currently under evaluation at the United States Department ofAgriculture USDA. This 4-plex assay detects antibodies for the three above-mentionedviruses as well as antibodies of avian reovirus. In the context of this study the ELISAs run inroutine diagnostics as well as a REO ELISA were used as the standard for comparison.Result: The antibody concentration in serum from vaccinated chickens was high while theantibody concentration level in serum from not vaccinated chickens was low.

Hundens roll i omvårdnaden av personer med demenssjukdom

Bakgrund: Idag lever minst 150 000 personer med demens i Sverige, år 2050 beräknas antalet ha fyrdubblats. Insatserna för personer med demens ska ge dem den hjälp de behöver i det sociala samspelet och ge dem en känsla av trygghet. Att som människa bli sedd och bekräftad ökar chansen för god hälsa, och eftersom hunden är expert på att tolka kroppsspråk och subtila signaler som människor lätt missar erbjuder den ett speciellt sällskap.Syfte: Beskriva hundens roll inom demenssjukvård.Frågeställningar: Hur kan hunden användas i omvårdnaden av personer med demenssjukdom? Vilka effekter har interventioner med hund på personer med demenssjukdom?Metod: Systematisk litteraturstudie.Resultat: Det finns i huvudsak två olika sätt att använda intervention med hund inom demenssjukvård, Animal Assisted Activity (AAA) och Animal Assisted Therapy (AAT). AAA fokuserar på trivsel och social samvaro medan AAT har fokus på individuell behandling.

Hand i hand i mörkret : En studie av de närståendes livsvärld när partnern drabbats av Alzheimers sjukdom

Studien utforskade de närståendes livsvärld när partnern drabbats av Alzheimers sjukdom. Deras livsvärld och existentiella villkor var i fokus. Studien utgick från ett existentiellt fenomenologiskt tolkande perspektiv. Den teoretiska grunden bestod av ett tänkande kring de närståendes livsvärld utifrån fyra existentialer: det levda rummet, den levda tiden, den levda kroppen och den levda relationen. Datainsamling skedde utifrån Max van Manens utforskande intervjuer med tio närstående, fem kvinnor och fem män i yrkesverksam ålder 40 till 64 år, de levde alla tillsammans med en partner som fått sin diagnos för ett år sedan eller längre.

Initial evaluation of the Meritas Troponin I test for measurement of equine cardiac troponin I

Cardiac troponin I (cTnI) is considered a specific and a sensitive biomarker of cardiac disease, and due to a high inter-species sequence homology; human cTnI assays can often be used in veterinary medicine. The main aim of this study was to perform an initial evaluation of a human cTnI test, the Meritas Troponin I test, for measurement of equine plasma cTnI, in order to investigate whether the test could be a possible subject for a more comprehensive validation. The hypothesis was that the test could measure equine cTnI, as there is a good homology between equine cTnI and human cTnI. The evaluation included a dilution parallelism, an intra-assay precision study and measurement of plasma cTnI healthy horses. In the dilution parallelism and the intra-assay precision study, equine plasma with previously established high cTnI concentration, according to another cTnI assay, was used. In addition, cTnI concentration was measured in plasma, collected from 19 horses, without signs of disease at physical and ECG examinations. The obtained curve in the dilution parallelism was linear, indicating that the Meritas Troponin I test can be used to measure different concentrations of equine cTnI in plasma.

Infectious bronchitis in Brazil : a minor field study in Bastos municipality, Sao Paulo

Infectious Bronchitis (IB) is a highly contagious viral respiratory and productiondepressant disease distributed world wide. The disease is caused by the InfectiousBronchitis Virus (IBV), a positive RNA strand Avian Coronavirus within thegenus Gammacoronavirus. Due to a combination of high mutation rate and atendency of recombination a constant emergence of new genotypes and serotypesis seen. In Brazil, a country with an extensive poultry production and majorproblems with disease control, the diversity of circulating strains are wide andoutbreaks of clinical disease despite intensive use of vaccines are common. Theaim of this study was to investigate the presence of IBV and to identify genotypesof isolated IBVs in a limited number of layer flocks in Bastos, São Paulo, as partof the screening for circulating genotypes in the country.

Amyloid beta inducerad klyvning av NG2 medierad via LRP-1 receptorn

Bakgrund: Deposition av fibrillär amyloid beta 1-42 (A?) i hjärnan är ett välkänt kännetecken för den neurodegenerativa sjukdomen Alzheimer?s (AD). Dessa ansamlingar påverkar pericyter, en celltyp involverad i blodkärlsfunktion och upprätthållande av blodhjärnbarriären (BBB). Pericyter uttrycker både receptorn low density lipoprotein receptor related protein 1 (LRP-1) till vilken A?1-42 binder, och proteoglykanet NG2.

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